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The map label for this gene is cinA [C]

Identifier: 124025048

GI number: 124025048

Start: 309216

End: 310508

Strand: Reverse

Name: cinA [C]

Synonym: NATL1_03351

Alternate gene names: 124025048

Gene position: 310508-309216 (Counterclockwise)

Preceding gene: 124025049

Following gene: 124025047

Centisome position: 16.65

GC content: 33.64

Gene sequence:

>1293_bases
GTGAAAACATCTAAAGAAATTACTATTAACAAAAAAAATAAATTTGGAGCAGAGATTTTATGCATTGGAAGTGAAATACT
TCTAGGAAATATTGTAAATACAAATTCTCAATGGATAGCAGAGCAATTAGCAATTTTAGGAATACCACATTTCAGACAAA
CCGTTATTGGAGATAACCCTGCAAGACTAGAAGAAGCAATACTTGAAGCATCTAATAGATCTGAAATTCTAATAACAACT
GGTGGGCTTGGCCCAACTCCAGATGATATAACAACGAAGGTGATTGCTGATACTTTCAAAACACCTCTAGAACAAAGAAA
TGATATATTGATTGACTTAAGAAACAAGTCAAAAGATAAGGATAGTAAATTATCCGATAGTCAAAAGAAGCAATCATTAG
TCCCAAAAGGGGCTAAAATTATAAACAATTACTCCGGCACAGCTCCTGGTATTTACTGGAGCCCAAAGGAAAATTTTACA
ATACTTACATTCCCTGGCGTCCCGAGTGAATTAAAAGAAATGTGGGCTAAAGAAGCATCAAAATTATTAATTAGTAATAA
TTTATCAAAAGAAGTTATCTCTAGCAAAGTTTTACATTTTGCTGGGATAAGTGAATCATTACTAGCAGACAAAATTCCTC
ATTTACTTATCTCTAAAAACCCAACTGTTGCAACTTATGCAAGAACTGGAGAAGTAAAGGTAAGAATCACAGCCAAAGGA
GAGAATTCGGAAGAAACCAATAGATTGATAGAACCTATTAAAAAAGAATTAACTCAAATCACTGGATTAAAATGCTTTGG
TATAGACAATGAAACTCTTGAAGAAATTGTATTTAAATTATTACTGAAAAGAAAAGAAACTATTGCTGTTGCAGAATCTT
GTACTGGAGGCGGAATAGGTTCTAAACTTACAAAAATCCCTGGATCTTCAAAAATTTTCCATGGAGGTGTCATCGCATAT
AACAATTCAATTAAACAGAGATTACTAGGGGTACCTGAGGAAATAATTAATACCCATGGTGCAGTTTCAAAGCCAGTTGT
CGAATCAATGGCGAGAGGCGTCCAAATAAAATTCAAAGTTAACTGGGCTATCTCTGTCAGTGGAATTGCAGGACCCACCG
GAGGAAGCAAATCAAAACCAGTTGGTCTAGTCAATTTTTGTATTAAGGGTCCAAAAACCCTTATTACATGGGAAGAAAAT
TTTGGATCTAATAAGACAAGAGAAGATATTCAAAAATTAAGCGTTTTAAATGCTCTTGATAGATTACGTTTATCTATAAT
CATGGCAAATTAA

Upstream 100 bases:

>100_bases
AATATCATTGCAGATAGACTACTTAACCCTAACGATGAAGATATAAAGGAAAATTCAATCAATAAAGTATCTGAACTTTG
CAATAAGTTTCCTTTATATA

Downstream 100 bases:

>100_bases
GTCCTCATTATTGGATTTGAAAGTTGAGTTCTAGAACCCTCTACGACAAAGTTTGGAACTTCCATCAGGTAAAAGAATTA
CCTGGAGGATCAACTCAACT

Product: molybdenum cofactor biosynthesis protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 430; Mature: 430

Protein sequence:

>430_residues
MKTSKEITINKKNKFGAEILCIGSEILLGNIVNTNSQWIAEQLAILGIPHFRQTVIGDNPARLEEAILEASNRSEILITT
GGLGPTPDDITTKVIADTFKTPLEQRNDILIDLRNKSKDKDSKLSDSQKKQSLVPKGAKIINNYSGTAPGIYWSPKENFT
ILTFPGVPSELKEMWAKEASKLLISNNLSKEVISSKVLHFAGISESLLADKIPHLLISKNPTVATYARTGEVKVRITAKG
ENSEETNRLIEPIKKELTQITGLKCFGIDNETLEEIVFKLLLKRKETIAVAESCTGGGIGSKLTKIPGSSKIFHGGVIAY
NNSIKQRLLGVPEEIINTHGAVSKPVVESMARGVQIKFKVNWAISVSGIAGPTGGSKSKPVGLVNFCIKGPKTLITWEEN
FGSNKTREDIQKLSVLNALDRLRLSIIMAN

Sequences:

>Translated_430_residues
MKTSKEITINKKNKFGAEILCIGSEILLGNIVNTNSQWIAEQLAILGIPHFRQTVIGDNPARLEEAILEASNRSEILITT
GGLGPTPDDITTKVIADTFKTPLEQRNDILIDLRNKSKDKDSKLSDSQKKQSLVPKGAKIINNYSGTAPGIYWSPKENFT
ILTFPGVPSELKEMWAKEASKLLISNNLSKEVISSKVLHFAGISESLLADKIPHLLISKNPTVATYARTGEVKVRITAKG
ENSEETNRLIEPIKKELTQITGLKCFGIDNETLEEIVFKLLLKRKETIAVAESCTGGGIGSKLTKIPGSSKIFHGGVIAY
NNSIKQRLLGVPEEIINTHGAVSKPVVESMARGVQIKFKVNWAISVSGIAGPTGGSKSKPVGLVNFCIKGPKTLITWEEN
FGSNKTREDIQKLSVLNALDRLRLSIIMAN
>Mature_430_residues
MKTSKEITINKKNKFGAEILCIGSEILLGNIVNTNSQWIAEQLAILGIPHFRQTVIGDNPARLEEAILEASNRSEILITT
GGLGPTPDDITTKVIADTFKTPLEQRNDILIDLRNKSKDKDSKLSDSQKKQSLVPKGAKIINNYSGTAPGIYWSPKENFT
ILTFPGVPSELKEMWAKEASKLLISNNLSKEVISSKVLHFAGISESLLADKIPHLLISKNPTVATYARTGEVKVRITAKG
ENSEETNRLIEPIKKELTQITGLKCFGIDNETLEEIVFKLLLKRKETIAVAESCTGGGIGSKLTKIPGSSKIFHGGVIAY
NNSIKQRLLGVPEEIINTHGAVSKPVVESMARGVQIKFKVNWAISVSGIAGPTGGSKSKPVGLVNFCIKGPKTLITWEEN
FGSNKTREDIQKLSVLNALDRLRLSIIMAN

Specific function: Unknown

COG id: COG1058

COG function: function code R; Predicted nucleotide-utilizing enzyme related to molybdopterin-biosynthesis enzyme MoeA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CinA family

Homologues:

Organism=Escherichia coli, GI1789052, Length=151, Percent_Identity=41.7218543046358, Blast_Score=111, Evalue=1e-25,
Organism=Escherichia coli, GI1788583, Length=290, Percent_Identity=27.9310344827586, Blast_Score=105, Evalue=4e-24,
Organism=Escherichia coli, GI1787818, Length=128, Percent_Identity=30.46875, Blast_Score=70, Evalue=2e-13,
Organism=Saccharomyces cerevisiae, GI6323832, Length=184, Percent_Identity=28.2608695652174, Blast_Score=75, Evalue=2e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): CINAL_PROM1 (A2C089)

Other databases:

- EMBL:   CP000553
- RefSeq:   YP_001014164.1
- ProteinModelPortal:   A2C089
- SMR:   A2C089
- STRING:   A2C089
- GeneID:   4779190
- GenomeReviews:   CP000553_GR
- KEGG:   pme:NATL1_03351
- eggNOG:   COG1058
- HOGENOM:   HBG449871
- OMA:   NPTVAPY
- ProtClustDB:   CLSK716108
- BioCyc:   PMAR167555:NATL1_03351-MONOMER
- HAMAP:   MF_00226_B
- InterPro:   IPR008136
- InterPro:   IPR008135
- InterPro:   IPR001453
- Gene3D:   G3DSA:3.40.980.10
- PIRSF:   PIRSF006728
- SMART:   SM00852
- TIGRFAMs:   TIGR00199
- TIGRFAMs:   TIGR00200

Pfam domain/function: PF02464 CinA; PF00994 MoCF_biosynth; SSF53218 MoCF_biosynth

EC number: NA

Molecular weight: Translated: 46889; Mature: 46889

Theoretical pI: Translated: 10.02; Mature: 10.02

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKTSKEITINKKNKFGAEILCIGSEILLGNIVNTNSQWIAEQLAILGIPHFRQTVIGDNP
CCCCCEEEEECCCCCCCEEEEECCCEEEEEEECCCHHHHHHHHHHHCCCHHHHHHCCCCH
ARLEEAILEASNRSEILITTGGLGPTPDDITTKVIADTFKTPLEQRNDILIDLRNKSKDK
HHHHHHHHCCCCCCEEEEEECCCCCCCHHHHHHHHHHHHHCHHHCCCCEEEEECCCCCCC
DSKLSDSQKKQSLVPKGAKIINNYSGTAPGIYWSPKENFTILTFPGVPSELKEMWAKEAS
CHHCCHHHHHHHCCCCCHHHHCCCCCCCCCEEECCCCCEEEEECCCCCHHHHHHHHHHHH
KLLISNNLSKEVISSKVLHFAGISESLLADKIPHLLISKNPTVATYARTGEVKVRITAKG
HHHHHCCCHHHHHHHHHHHHCCCCHHHHHHHCCCEEECCCCCEEEEEECCEEEEEEEECC
ENSEETNRLIEPIKKELTQITGLKCFGIDNETLEEIVFKLLLKRKETIAVAESCTGGGIG
CCCHHHHHHHHHHHHHHHHHCCEEEECCCHHHHHHHHHHHHHHCCHHHEEHHCCCCCCCC
SKLTKIPGSSKIFHGGVIAYNNSIKQRLLGVPEEIINTHGAVSKPVVESMARGVQIKFKV
CHHHCCCCCCCEEECCEEEECCHHHHHHHCCCHHHHHCCCCCCHHHHHHHHCCEEEEEEE
NWAISVSGIAGPTGGSKSKPVGLVNFCIKGPKTLITWEENFGSNKTREDIQKLSVLNALD
EEEEEECCCCCCCCCCCCCCCEEEEEEECCCCEEEEECCCCCCCCHHHHHHHHHHHHHHH
RLRLSIIMAN
HHEEEEEEEC
>Mature Secondary Structure
MKTSKEITINKKNKFGAEILCIGSEILLGNIVNTNSQWIAEQLAILGIPHFRQTVIGDNP
CCCCCEEEEECCCCCCCEEEEECCCEEEEEEECCCHHHHHHHHHHHCCCHHHHHHCCCCH
ARLEEAILEASNRSEILITTGGLGPTPDDITTKVIADTFKTPLEQRNDILIDLRNKSKDK
HHHHHHHHCCCCCCEEEEEECCCCCCCHHHHHHHHHHHHHCHHHCCCCEEEEECCCCCCC
DSKLSDSQKKQSLVPKGAKIINNYSGTAPGIYWSPKENFTILTFPGVPSELKEMWAKEAS
CHHCCHHHHHHHCCCCCHHHHCCCCCCCCCEEECCCCCEEEEECCCCCHHHHHHHHHHHH
KLLISNNLSKEVISSKVLHFAGISESLLADKIPHLLISKNPTVATYARTGEVKVRITAKG
HHHHHCCCHHHHHHHHHHHHCCCCHHHHHHHCCCEEECCCCCEEEEEECCEEEEEEEECC
ENSEETNRLIEPIKKELTQITGLKCFGIDNETLEEIVFKLLLKRKETIAVAESCTGGGIG
CCCHHHHHHHHHHHHHHHHHCCEEEECCCHHHHHHHHHHHHHHCCHHHEEHHCCCCCCCC
SKLTKIPGSSKIFHGGVIAYNNSIKQRLLGVPEEIINTHGAVSKPVVESMARGVQIKFKV
CHHHCCCCCCCEEECCEEEECCHHHHHHHCCCHHHHHCCCCCCHHHHHHHHCCEEEEEEE
NWAISVSGIAGPTGGSKSKPVGLVNFCIKGPKTLITWEENFGSNKTREDIQKLSVLNALD
EEEEEECCCCCCCCCCCCCCCEEEEEEECCCCEEEEECCCCCCCCHHHHHHHHHHHHHHH
RLRLSIIMAN
HHEEEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA