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The map label for this gene is moaC [H]

Identifier: 124027780

GI number: 124027780

Start: 914818

End: 915270

Strand: Reverse

Name: moaC [H]

Synonym: Hbut_0907

Alternate gene names: 124027780

Gene position: 915270-914818 (Counterclockwise)

Preceding gene: 124027781

Following gene: 124027778

Centisome position: 54.9

GC content: 46.8

Gene sequence:

>453_bases
ATGAGCAGAAAACCCTCCATGGTTGATATAACTGCTAAGAATGTTATTGTACGCGAAGCAGAAGCTTACGGCAGAATAAA
GCTACGCCCAGAAACAATAAGTCGTATACTTGAGGGTAAAATTGAGAAGGGCGACCCCTTAACCGTGGCGTCGATAGCAG
GTATACAAGCTGCGAAGCTTACGCCATTACTGCTGCCCATGTGTCACCCCATAGAGATAACTAAGGTTGACGTCGAATGC
AGGGTTGAGGATAACGAGCATGTAGGCTGTCGTGCCTACGTAAAAGCTGTAGCACGCACTGGCGTCGAAATGGAGGCCTT
GACAGCTGTTACTGTGGCCTTACTCAATGTATGGGATATGGTTAAGAAGTACGAGAAAGATGAGCGTGGGCTATACCCGC
ACACTGTTATAGAAGAGGTAAAGGTTACAAGCAAAGTCAAACACGGCTCATAA

Upstream 100 bases:

>100_bases
AGGAGACACGTGTCGGAAGAGCTAGGCTTTACAGCTTAAAGCTCAACAACCCAAGGACACTAGTACTGGTTGAAACACTG
AGACTCCTAGGTGAGTCTCT

Downstream 100 bases:

>100_bases
AAGGAGTCTAGAATAGTGTTGTTTGAGTACCGCTACCCTTACCTCTCCTTCTAGACTTACTAGTTCTACGGCGAGATGTA
CTAGTTCTCTTAGCCGCTCT

Product: molybdenum cofactor biosynthesis protein C

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 150; Mature: 149

Protein sequence:

>150_residues
MSRKPSMVDITAKNVIVREAEAYGRIKLRPETISRILEGKIEKGDPLTVASIAGIQAAKLTPLLLPMCHPIEITKVDVEC
RVEDNEHVGCRAYVKAVARTGVEMEALTAVTVALLNVWDMVKKYEKDERGLYPHTVIEEVKVTSKVKHGS

Sequences:

>Translated_150_residues
MSRKPSMVDITAKNVIVREAEAYGRIKLRPETISRILEGKIEKGDPLTVASIAGIQAAKLTPLLLPMCHPIEITKVDVEC
RVEDNEHVGCRAYVKAVARTGVEMEALTAVTVALLNVWDMVKKYEKDERGLYPHTVIEEVKVTSKVKHGS
>Mature_149_residues
SRKPSMVDITAKNVIVREAEAYGRIKLRPETISRILEGKIEKGDPLTVASIAGIQAAKLTPLLLPMCHPIEITKVDVECR
VEDNEHVGCRAYVKAVARTGVEMEALTAVTVALLNVWDMVKKYEKDERGLYPHTVIEEVKVTSKVKHGS

Specific function: Together with moaA, is involved in the conversion of a guanosine derivative (5'-GTP) into molybdopterin precursor Z [H]

COG id: COG0315

COG function: function code H; Molybdenum cofactor biosynthesis enzyme

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the moaC family [H]

Homologues:

Organism=Escherichia coli, GI1787001, Length=122, Percent_Identity=45.9016393442623, Blast_Score=107, Evalue=3e-25,
Organism=Caenorhabditis elegans, GI32566331, Length=116, Percent_Identity=45.6896551724138, Blast_Score=91, Evalue=3e-19,
Organism=Drosophila melanogaster, GI28574492, Length=122, Percent_Identity=43.4426229508197, Blast_Score=91, Evalue=4e-19,
Organism=Drosophila melanogaster, GI28574490, Length=125, Percent_Identity=43.2, Blast_Score=90, Evalue=5e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR023045
- InterPro:   IPR023047
- InterPro:   IPR002820 [H]

Pfam domain/function: PF01967 MoaC [H]

EC number: NA

Molecular weight: Translated: 16636; Mature: 16505

Theoretical pI: Translated: 8.47; Mature: 8.47

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
5.3 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSRKPSMVDITAKNVIVREAEAYGRIKLRPETISRILEGKIEKGDPLTVASIAGIQAAKL
CCCCCCEEEEECCCEEEEEHHHCCEEEECHHHHHHHHCCCCCCCCCEEEEHHCCCCHHHC
TPLLLPMCHPIEITKVDVECRVEDNEHVGCRAYVKAVARTGVEMEALTAVTVALLNVWDM
CHHHHCCCCCCEEEEEEEEEEECCCCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHH
VKKYEKDERGLYPHTVIEEVKVTSKVKHGS
HHHHHHHCCCCCCHHHHHHHHHHHHCCCCC
>Mature Secondary Structure 
SRKPSMVDITAKNVIVREAEAYGRIKLRPETISRILEGKIEKGDPLTVASIAGIQAAKL
CCCCCEEEEECCCEEEEEHHHCCEEEECHHHHHHHHCCCCCCCCCEEEEHHCCCCHHHC
TPLLLPMCHPIEITKVDVECRVEDNEHVGCRAYVKAVARTGVEMEALTAVTVALLNVWDM
CHHHHCCCCCCEEEEEEEEEEECCCCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHH
VKKYEKDERGLYPHTVIEEVKVTSKVKHGS
HHHHHHHCCCCCCHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Involved in molybdopterin biosynthesis [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10701121; 11427726 [H]