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The map label for this gene is pelA

Identifier: 124027768

GI number: 124027768

Start: 896555

End: 897637

Strand: Reverse

Name: pelA

Synonym: Hbut_0894

Alternate gene names: 124027768

Gene position: 897637-896555 (Counterclockwise)

Preceding gene: 124027777

Following gene: 124027765

Centisome position: 53.84

GC content: 52.91

Gene sequence:

>1083_bases
ATGAAAATCCTAGCGGTCGACACTAAGCGAGGCCTTGTAAGAGTTGTACCAGAGACCACCGATGACATCTGGCTACTATC
AACAGTTATACAGCCAGGTGATCTTGTCCGCGCGAAGACACTGCGCGAGATACATTTCGGGGATCGCGGATCCGGTAGAA
GTAGCCGCATACCAATGGTTCTCACCGTGCGAGTAGAGGCTGTAGAGTTCCAGGCCTTTACGACGAGGCTGCGTATCCGC
GGCATAGTCATTGAGGGCCCGGAAAAGTATGGCGTAGTGGGTAAGTACCATACACTTAGTATCGAGCCTGGCCGTGAGTT
AGACATAGTAAAGCCTAGTGGTTGGCCTCAAGTCCTCATAGAGAAGCTCAAGCGAGGCTCCTACAACGTGGCGGCTGTAG
TCGTAGCGGTAGACTATGACGACTATGCTGTTGCCGTTGTGCGGGGACAAGGGGTCAAGATACTTGCTAGTGGCGGTTTA
CATCTCCCAGGGAAAGATGATCCTACGAGGGAGGATAAGCTCCGCGAAGCAGTAACAGTAATTGCCAAGACTACAGCTGA
TGTTGCTAGAAGAGAGAATGCCCTCCTGGTGGTGGCGGCAGGGCCTGGCACAGTCAAGAACCTTGTCGCAGAAAAGCTGC
GGGGACTAGTGCAAGGCGTAAAGATACTCGTTGACAATGTTTCTATGGGCGGCGAGGCAGGTGTGTTTGAGGAGGTTAGA
CGTGGCATTATGAGACAAGCGCTCCAGGATGCCGCTGTTGTTGAGGCTGAGAGGATACTCGAGGAGTTTGAGAGGAGGCT
GGCAAAGGAGCCGGGAAGGATTGCTTACACGTTGGAACAGGTTTACAGGGCTGCCGAGATGGGCGCAGTAGAAGAGCTGC
TAATTCTTGACGAGACGTTACATCATCCTGATCCCGAGGTTAGGGCTAGGGTTGACGAACTGCTAAGACTTGCAGACGCT
ACACGTGCAAAAATACACTTTGTCAGCGTTGAGTCACCCGTGGGGTATAAGGTTAAGGCGCTAGGTGGCGTTATCGCATT
ACTCCGCTATGCTATCAACTTCGCTGGGGAGACGGGAGGCTAG

Upstream 100 bases:

>100_bases
GACTTGCCCCAGCTCACGACGCTCCACTGGACGTACTTTTACGCAGCAGTTCAAGGAGTAATTTACCCCATACCCCATAC
CGTGTGGTAGAGGGTGCATT

Downstream 100 bases:

>100_bases
TCTACGGGATGGGTAGACGCGCACTATTCTTGCACTGGGCACCATCTCTGCCAGCGAGGCGGGACCAGCATATCCCACCT
TTAGCCTTTCTAGAAGCTCG

Product: RNA-binding protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 360; Mature: 360

Protein sequence:

>360_residues
MKILAVDTKRGLVRVVPETTDDIWLLSTVIQPGDLVRAKTLREIHFGDRGSGRSSRIPMVLTVRVEAVEFQAFTTRLRIR
GIVIEGPEKYGVVGKYHTLSIEPGRELDIVKPSGWPQVLIEKLKRGSYNVAAVVVAVDYDDYAVAVVRGQGVKILASGGL
HLPGKDDPTREDKLREAVTVIAKTTADVARRENALLVVAAGPGTVKNLVAEKLRGLVQGVKILVDNVSMGGEAGVFEEVR
RGIMRQALQDAAVVEAERILEEFERRLAKEPGRIAYTLEQVYRAAEMGAVEELLILDETLHHPDPEVRARVDELLRLADA
TRAKIHFVSVESPVGYKVKALGGVIALLRYAINFAGETGG

Sequences:

>Translated_360_residues
MKILAVDTKRGLVRVVPETTDDIWLLSTVIQPGDLVRAKTLREIHFGDRGSGRSSRIPMVLTVRVEAVEFQAFTTRLRIR
GIVIEGPEKYGVVGKYHTLSIEPGRELDIVKPSGWPQVLIEKLKRGSYNVAAVVVAVDYDDYAVAVVRGQGVKILASGGL
HLPGKDDPTREDKLREAVTVIAKTTADVARRENALLVVAAGPGTVKNLVAEKLRGLVQGVKILVDNVSMGGEAGVFEEVR
RGIMRQALQDAAVVEAERILEEFERRLAKEPGRIAYTLEQVYRAAEMGAVEELLILDETLHHPDPEVRARVDELLRLADA
TRAKIHFVSVESPVGYKVKALGGVIALLRYAINFAGETGG
>Mature_360_residues
MKILAVDTKRGLVRVVPETTDDIWLLSTVIQPGDLVRAKTLREIHFGDRGSGRSSRIPMVLTVRVEAVEFQAFTTRLRIR
GIVIEGPEKYGVVGKYHTLSIEPGRELDIVKPSGWPQVLIEKLKRGSYNVAAVVVAVDYDDYAVAVVRGQGVKILASGGL
HLPGKDDPTREDKLREAVTVIAKTTADVARRENALLVVAAGPGTVKNLVAEKLRGLVQGVKILVDNVSMGGEAGVFEEVR
RGIMRQALQDAAVVEAERILEEFERRLAKEPGRIAYTLEQVYRAAEMGAVEELLILDETLHHPDPEVRARVDELLRLADA
TRAKIHFVSVESPVGYKVKALGGVIALLRYAINFAGETGG

Specific function: May function in recognizing stalled ribosomes, interact with stem-loop structures in stalled mRNA molecules, and effect endonucleolytic cleavage of the mRNA. May play a role in the release non-functional ribosomes and degradation of damaged mRNAs. Has end

COG id: COG1537

COG function: function code R; Predicted RNA-binding proteins

Gene ontology:

Cell location: Cytoplasm (Potential)

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the eukaryotic release factor 1 family. Pelota subfamily

Homologues:

Organism=Homo sapiens, GI31880783, Length=369, Percent_Identity=28.1842818428184, Blast_Score=119, Evalue=6e-27,
Organism=Caenorhabditis elegans, GI17554648, Length=373, Percent_Identity=23.0563002680965, Blast_Score=80, Evalue=2e-15,
Organism=Drosophila melanogaster, GI17136914, Length=382, Percent_Identity=26.7015706806283, Blast_Score=107, Evalue=1e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): PELO_HYPBU (A2BL82)

Other databases:

- EMBL:   CP000493
- RefSeq:   YP_001013088.1
- ProteinModelPortal:   A2BL82
- SMR:   A2BL82
- STRING:   A2BL82
- GeneID:   4781990
- GenomeReviews:   CP000493_GR
- KEGG:   hbu:Hbut_0894
- eggNOG:   arNOG04486
- HOGENOM:   HBG646058
- OMA:   GVKGRRH
- BioCyc:   HBUT415426:HBUT_0894-MONOMER
- GO:   GO:0005737
- GO:   GO:0006412
- HAMAP:   MF_01853
- InterPro:   IPR005140
- InterPro:   IPR005141
- InterPro:   IPR005142
- InterPro:   IPR004405
- PANTHER:   PTHR10853
- TIGRFAMs:   TIGR00111

Pfam domain/function: PF03463 eRF1_1; PF03464 eRF1_2; PF03465 eRF1_3

EC number: NA

Molecular weight: Translated: 39374; Mature: 39374

Theoretical pI: Translated: 8.69; Mature: 8.69

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
1.4 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
1.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKILAVDTKRGLVRVVPETTDDIWLLSTVIQPGDLVRAKTLREIHFGDRGSGRSSRIPMV
CEEEEEECCCCEEEECCCCCCCEEEHHHHCCCCCHHHHHHHHHHCCCCCCCCCCCCCCEE
LTVRVEAVEFQAFTTRLRIRGIVIEGPEKYGVVGKYHTLSIEPGRELDIVKPSGWPQVLI
EEEEEEEEEHHHHHEEEEEEEEEEECCCCCCCEEEEEEEEECCCCCEEEECCCCCHHHHH
EKLKRGSYNVAAVVVAVDYDDYAVAVVRGQGVKILASGGLHLPGKDDPTREDKLREAVTV
HHHHCCCCCEEEEEEEEECCCEEEEEEECCCEEEEECCCEECCCCCCCCHHHHHHHHHHH
IAKTTADVARRENALLVVAAGPGTVKNLVAEKLRGLVQGVKILVDNVSMGGEAGVFEEVR
HHHHHHHHHHCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHH
RGIMRQALQDAAVVEAERILEEFERRLAKEPGRIAYTLEQVYRAAEMGAVEELLILDETL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEHHHHHHHHHHHCCHHHHHHHHHHHH
HHPDPEVRARVDELLRLADATRAKIHFVSVESPVGYKVKALGGVIALLRYAINFAGETGG
CCCCHHHHHHHHHHHHHHCCCCEEEEEEEECCCCCEEHHHHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure
MKILAVDTKRGLVRVVPETTDDIWLLSTVIQPGDLVRAKTLREIHFGDRGSGRSSRIPMV
CEEEEEECCCCEEEECCCCCCCEEEHHHHCCCCCHHHHHHHHHHCCCCCCCCCCCCCCEE
LTVRVEAVEFQAFTTRLRIRGIVIEGPEKYGVVGKYHTLSIEPGRELDIVKPSGWPQVLI
EEEEEEEEEHHHHHEEEEEEEEEEECCCCCCCEEEEEEEEECCCCCEEEECCCCCHHHHH
EKLKRGSYNVAAVVVAVDYDDYAVAVVRGQGVKILASGGLHLPGKDDPTREDKLREAVTV
HHHHCCCCCEEEEEEEEECCCEEEEEEECCCEEEEECCCEECCCCCCCCHHHHHHHHHHH
IAKTTADVARRENALLVVAAGPGTVKNLVAEKLRGLVQGVKILVDNVSMGGEAGVFEEVR
HHHHHHHHHHCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHH
RGIMRQALQDAAVVEAERILEEFERRLAKEPGRIAYTLEQVYRAAEMGAVEELLILDETL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEHHHHHHHHHHHCCHHHHHHHHHHHH
HHPDPEVRARVDELLRLADATRAKIHFVSVESPVGYKVKALGGVIALLRYAINFAGETGG
CCCCHHHHHHHHHHHHHHCCCCEEEEEEEECCCCCEEHHHHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA