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The map label for this gene is pyrR [H]

Identifier: 123966844

GI number: 123966844

Start: 1408430

End: 1408969

Strand: Reverse

Name: pyrR [H]

Synonym: P9515_16111

Alternate gene names: 123966844

Gene position: 1408969-1408430 (Counterclockwise)

Preceding gene: 123966848

Following gene: 123966842

Centisome position: 82.68

GC content: 33.15

Gene sequence:

>540_bases
ATGTCCAATCAAGATAAAAGAATCACAATACTTACTGAAGATGAGTTAAGAAAAACTCTCTCGCGCTTAACTTTTGAAAT
TATTGAAAAGATCTCAAATTTAGAAAATCTCTTATTGGTTGGTATCCCTACGAGAGGAGTTCATCTCGCTGAAGTTTTGA
GAAAAGACATGTTTGATAAAACTGGGATTAATGTAAATAAAGGAATAATAGATCCGACTTTCTATAGAGATGATCAAAAT
AGAGTTGGAACTCGTCTAATTGAGGCAACTGATTTTCCTACTTCAATAGAAAAAAAAGATATTGTTTTAATTGATGATGT
TATTTATACAGGAAGAACAATTCGAGCTGCGATTGAGGCTCTTCTTTTATGGGGAAGACCGAAAAGAGTAATGTTATTAG
TAATGATTGATAGAGGACATAGAGAACTACCAATTCAGCCTGATTTTTGTGGAAGAAAAGTTCCTACTAACAAAAAAGAA
ACTGTTCATTTATGTTTAAAGCAAGTGGACGGGGAAGAGGGTATCTTCTTGGATCGTTAA

Upstream 100 bases:

>100_bases
AATTTAGCTGTAAAAGCAGTTCCATACAATTTATATTTAATTTAGTTAGCTTTTGCTAATTTAAATAGGATGTTGAATAA
AGTTAATTTTCATGTGAGTC

Downstream 100 bases:

>100_bases
TGTTTAAAAGATATTTCCTAAATTAGATTCGCCTAATTCTTTTTCATTAATATCTAGATATTTTACATAAAGAGATGAAT
CCTTCGTAATACTGAAATAG

Product: bifunctional pyrimidine regulatory protein PyrR uracil phosphoribosyltransferase

Products: NA

Alternate protein names: Pyrimidine operon regulatory protein; Uracil phosphoribosyltransferase; UPRTase [H]

Number of amino acids: Translated: 179; Mature: 178

Protein sequence:

>179_residues
MSNQDKRITILTEDELRKTLSRLTFEIIEKISNLENLLLVGIPTRGVHLAEVLRKDMFDKTGINVNKGIIDPTFYRDDQN
RVGTRLIEATDFPTSIEKKDIVLIDDVIYTGRTIRAAIEALLLWGRPKRVMLLVMIDRGHRELPIQPDFCGRKVPTNKKE
TVHLCLKQVDGEEGIFLDR

Sequences:

>Translated_179_residues
MSNQDKRITILTEDELRKTLSRLTFEIIEKISNLENLLLVGIPTRGVHLAEVLRKDMFDKTGINVNKGIIDPTFYRDDQN
RVGTRLIEATDFPTSIEKKDIVLIDDVIYTGRTIRAAIEALLLWGRPKRVMLLVMIDRGHRELPIQPDFCGRKVPTNKKE
TVHLCLKQVDGEEGIFLDR
>Mature_178_residues
SNQDKRITILTEDELRKTLSRLTFEIIEKISNLENLLLVGIPTRGVHLAEVLRKDMFDKTGINVNKGIIDPTFYRDDQNR
VGTRLIEATDFPTSIEKKDIVLIDDVIYTGRTIRAAIEALLLWGRPKRVMLLVMIDRGHRELPIQPDFCGRKVPTNKKET
VHLCLKQVDGEEGIFLDR

Specific function: Displays also a weak uracil phosphoribosyltransferase activity which is not physiologically significant [H]

COG id: COG2065

COG function: function code F; Pyrimidine operon attenuation protein/uracil phosphoribosyltransferase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrR subfamily [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000836
- InterPro:   IPR023050 [H]

Pfam domain/function: PF00156 Pribosyltran [H]

EC number: =2.4.2.9 [H]

Molecular weight: Translated: 20580; Mature: 20449

Theoretical pI: Translated: 8.23; Mature: 8.23

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSNQDKRITILTEDELRKTLSRLTFEIIEKISNLENLLLVGIPTRGVHLAEVLRKDMFDK
CCCCCCEEEEEEHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCHHHHHHHHHHHHHH
TGINVNKGIIDPTFYRDDQNRVGTRLIEATDFPTSIEKKDIVLIDDVIYTGRTIRAAIEA
CCCCCCCCCCCCCEEECCCHHHHHEEEECCCCCCCCCCCCEEEEECHHHCCHHHHHHHHH
LLLWGRPKRVMLLVMIDRGHRELPIQPDFCGRKVPTNKKETVHLCLKQVDGEEGIFLDR
HHHCCCCCCEEEEEEECCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCCEEECC
>Mature Secondary Structure 
SNQDKRITILTEDELRKTLSRLTFEIIEKISNLENLLLVGIPTRGVHLAEVLRKDMFDK
CCCCCEEEEEEHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCHHHHHHHHHHHHHH
TGINVNKGIIDPTFYRDDQNRVGTRLIEATDFPTSIEKKDIVLIDDVIYTGRTIRAAIEA
CCCCCCCCCCCCCEEECCCHHHHHEEEECCCCCCCCCCCCEEEEECHHHCCHHHHHHHHH
LLLWGRPKRVMLLVMIDRGHRELPIQPDFCGRKVPTNKKETVHLCLKQVDGEEGIFLDR
HHHCCCCCCEEEEEEECCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCCEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA