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The map label for this gene is yugS [H]

Identifier: 123965542

GI number: 123965542

Start: 282505

End: 283773

Strand: Reverse

Name: yugS [H]

Synonym: P9515_03071

Alternate gene names: 123965542

Gene position: 283773-282505 (Counterclockwise)

Preceding gene: 123965545

Following gene: 123965541

Centisome position: 16.65

GC content: 31.05

Gene sequence:

>1269_bases
ATGAAAATAACTTTACTTTTTTTACTTTTGATGTTTCCAGCTTTTTTTGCTGCAAGTGAACTTTCATTTTTATTAATAAG
ACCAAGTAAAGTTTTAAGACTGATAGAAGAGAAAAGAAAAGGGGCATTTTCAATTTTAAAAATTCAAAAAAGATTCATAT
CTTCCTTAATAGCTTCTCAATTTGGAGTAACAATTTCTCTAATAGCTATTGGTTGGTTAAGTAAAGGTTTAGCTAATGAT
TTTTGGAACGAAAATAAATTTTCAAATCGAATATATGATCTCTTAATGTTTTTATTTATAGTACTTATCGTCACCCTCAT
ATCAGGTCTTATTCCTAAAGCATTAGTAATTAATAATCCAGAGTCAGCTGCTTTGAGATTAACTACAATTTTTGATGCTG
TTCGTAAAGGAATGCAACCTATTGTTTCTGTAATTGAATTTTTTGCAAGCGCTTGTTTAAGGTTATTTCATCTAAACAAC
AAATGGGATTCATTAAATTCAGTATTATCAGCGGGTGAATTAGAAACTTTAATAGAAACAGATAATGTCACAGGATTAAA
ACCTGATGAGAAAAATATCTTAGAAGGTGTTTTTGCTTTAAAAGATACTCAAGTCAAAGAAGTAATGATTCCAAGATCTG
AAATGGTAACTTTGCCAAAAAATATTACGTTTGCTGAACTTATGAAACAAGTTGATAAAACAAGGCATGCTCGTTTTTTT
GTGATTGGTGAATCACTAGATGATGTTTTAGGGGTTTTAGATTTACGTTACTTAGCAAAACCAATATCCAAAAGCGAAAT
GGAAGCAAATACATTATTAGAACCTTTCCTTTTACCTGTGACAAAAGTCATTGAGACATGCTCGTTAGCAGAGATATTGC
CTCTCGTTAGAGACTATAATCCATTTTTGCTTGTTGTTGATGAACATGGTGGAACTGAGGGGCTCATAACTGCCGCTGAT
CTTACTGGAGAAATTGTTGGAGAAGAAAGACTGAGTAGCAGGATATATTCTGATATGAAAATGTTAGATAATTTCTCCAG
AAAGTGGTCAATTGCAGGAAAAGCAGAAATAATAGAAATCAATAAAAAGTTGGGATGTTTTCTTCCAGAAGGAGCTGATT
ACCATACACTAGCAGGATTTCTTCTTGAAAAATTTCAAATGGTTCCCAAAATTGGAGATAGTTTAGATTTCAAAAATATT
AAATTTGAAATAATTTCAATGTCAGGTCCCAAAATTGATCGTGTAAAAATATTTCTGCCAAAAAGTTAA

Upstream 100 bases:

>100_bases
GCAAAATCCGGGGGTGTAGCAATCTGGTGAATGCACCAAACTCATAATTTGGCTAAGGCGAGTTCGATCCTCGCCACCCC
CATCACTAATTTGTTAACGA

Downstream 100 bases:

>100_bases
AATTGACATCCAATGAAGGATAATAACTTAATATACATGGACTATAAGATATGAAACCAACCTCATCTTCAGTAAAGGTT
GGAGTAATCGGGATAGGAAA

Product: hemolysin-like protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 422; Mature: 422

Protein sequence:

>422_residues
MKITLLFLLLMFPAFFAASELSFLLIRPSKVLRLIEEKRKGAFSILKIQKRFISSLIASQFGVTISLIAIGWLSKGLAND
FWNENKFSNRIYDLLMFLFIVLIVTLISGLIPKALVINNPESAALRLTTIFDAVRKGMQPIVSVIEFFASACLRLFHLNN
KWDSLNSVLSAGELETLIETDNVTGLKPDEKNILEGVFALKDTQVKEVMIPRSEMVTLPKNITFAELMKQVDKTRHARFF
VIGESLDDVLGVLDLRYLAKPISKSEMEANTLLEPFLLPVTKVIETCSLAEILPLVRDYNPFLLVVDEHGGTEGLITAAD
LTGEIVGEERLSSRIYSDMKMLDNFSRKWSIAGKAEIIEINKKLGCFLPEGADYHTLAGFLLEKFQMVPKIGDSLDFKNI
KFEIISMSGPKIDRVKIFLPKS

Sequences:

>Translated_422_residues
MKITLLFLLLMFPAFFAASELSFLLIRPSKVLRLIEEKRKGAFSILKIQKRFISSLIASQFGVTISLIAIGWLSKGLAND
FWNENKFSNRIYDLLMFLFIVLIVTLISGLIPKALVINNPESAALRLTTIFDAVRKGMQPIVSVIEFFASACLRLFHLNN
KWDSLNSVLSAGELETLIETDNVTGLKPDEKNILEGVFALKDTQVKEVMIPRSEMVTLPKNITFAELMKQVDKTRHARFF
VIGESLDDVLGVLDLRYLAKPISKSEMEANTLLEPFLLPVTKVIETCSLAEILPLVRDYNPFLLVVDEHGGTEGLITAAD
LTGEIVGEERLSSRIYSDMKMLDNFSRKWSIAGKAEIIEINKKLGCFLPEGADYHTLAGFLLEKFQMVPKIGDSLDFKNI
KFEIISMSGPKIDRVKIFLPKS
>Mature_422_residues
MKITLLFLLLMFPAFFAASELSFLLIRPSKVLRLIEEKRKGAFSILKIQKRFISSLIASQFGVTISLIAIGWLSKGLAND
FWNENKFSNRIYDLLMFLFIVLIVTLISGLIPKALVINNPESAALRLTTIFDAVRKGMQPIVSVIEFFASACLRLFHLNN
KWDSLNSVLSAGELETLIETDNVTGLKPDEKNILEGVFALKDTQVKEVMIPRSEMVTLPKNITFAELMKQVDKTRHARFF
VIGESLDDVLGVLDLRYLAKPISKSEMEANTLLEPFLLPVTKVIETCSLAEILPLVRDYNPFLLVVDEHGGTEGLITAAD
LTGEIVGEERLSSRIYSDMKMLDNFSRKWSIAGKAEIIEINKKLGCFLPEGADYHTLAGFLLEKFQMVPKIGDSLDFKNI
KFEIISMSGPKIDRVKIFLPKS

Specific function: Unknown

COG id: COG1253

COG function: function code R; Hemolysins and related proteins containing CBS domains

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 CBS domains [H]

Homologues:

Organism=Homo sapiens, GI310128564, Length=384, Percent_Identity=23.4375, Blast_Score=106, Evalue=5e-23,
Organism=Escherichia coli, GI1790664, Length=442, Percent_Identity=23.3031674208145, Blast_Score=100, Evalue=3e-22,
Organism=Escherichia coli, GI1786879, Length=276, Percent_Identity=27.536231884058, Blast_Score=99, Evalue=6e-22,
Organism=Escherichia coli, GI145693175, Length=424, Percent_Identity=22.6415094339623, Blast_Score=98, Evalue=9e-22,
Organism=Escherichia coli, GI87082033, Length=261, Percent_Identity=24.904214559387, Blast_Score=85, Evalue=7e-18,
Organism=Escherichia coli, GI1788119, Length=233, Percent_Identity=22.7467811158798, Blast_Score=68, Evalue=9e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016169
- InterPro:   IPR000644
- InterPro:   IPR002550
- InterPro:   IPR005170 [H]

Pfam domain/function: PF00571 CBS; PF03471 CorC_HlyC; PF01595 DUF21 [H]

EC number: NA

Molecular weight: Translated: 47430; Mature: 47430

Theoretical pI: Translated: 7.50; Mature: 7.50

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKITLLFLLLMFPAFFAASELSFLLIRPSKVLRLIEEKRKGAFSILKIQKRFISSLIASQ
CHHHHHHHHHHHHHHHHHCCCEEEEECHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHH
FGVTISLIAIGWLSKGLANDFWNENKFSNRIYDLLMFLFIVLIVTLISGLIPKALVINNP
HCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEECCC
ESAALRLTTIFDAVRKGMQPIVSVIEFFASACLRLFHLNNKWDSLNSVLSAGELETLIET
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCHHHHHHCC
DNVTGLKPDEKNILEGVFALKDTQVKEVMIPRSEMVTLPKNITFAELMKQVDKTRHARFF
CCCCCCCCCHHHHHHHHHHHCCCHHHHHHCCCHHHEECCCCCCHHHHHHHHHHHHCCEEE
VIGESLDDVLGVLDLRYLAKPISKSEMEANTLLEPFLLPVTKVIETCSLAEILPLVRDYN
EECCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
PFLLVVDEHGGTEGLITAADLTGEIVGEERLSSRIYSDMKMLDNFSRKWSIAGKAEIIEI
CEEEEEECCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEE
NKKLGCFLPEGADYHTLAGFLLEKFQMVPKIGDSLDFKNIKFEIISMSGPKIDRVKIFLP
CCHHCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEEECCCCCCCEEEEEEC
KS
CC
>Mature Secondary Structure
MKITLLFLLLMFPAFFAASELSFLLIRPSKVLRLIEEKRKGAFSILKIQKRFISSLIASQ
CHHHHHHHHHHHHHHHHHCCCEEEEECHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHH
FGVTISLIAIGWLSKGLANDFWNENKFSNRIYDLLMFLFIVLIVTLISGLIPKALVINNP
HCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEECCC
ESAALRLTTIFDAVRKGMQPIVSVIEFFASACLRLFHLNNKWDSLNSVLSAGELETLIET
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCHHHHHHCC
DNVTGLKPDEKNILEGVFALKDTQVKEVMIPRSEMVTLPKNITFAELMKQVDKTRHARFF
CCCCCCCCCHHHHHHHHHHHCCCHHHHHHCCCHHHEECCCCCCHHHHHHHHHHHHCCEEE
VIGESLDDVLGVLDLRYLAKPISKSEMEANTLLEPFLLPVTKVIETCSLAEILPLVRDYN
EECCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
PFLLVVDEHGGTEGLITAADLTGEIVGEERLSSRIYSDMKMLDNFSRKWSIAGKAEIIEI
CEEEEEECCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEE
NKKLGCFLPEGADYHTLAGFLLEKFQMVPKIGDSLDFKNIKFEIISMSGPKIDRVKIFLP
CCHHCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEEECCCCCCCEEEEEEC
KS
CC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9274030; 9384377 [H]