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The map label for this gene is hppA [H]

Identifier: 121609947

GI number: 121609947

Start: 3349856

End: 3351934

Strand: Direct

Name: hppA [H]

Synonym: Veis_3003

Alternate gene names: 121609947

Gene position: 3349856-3351934 (Clockwise)

Preceding gene: 121609928

Following gene: 121609948

Centisome position: 60.18

GC content: 66.96

Gene sequence:

>2079_bases
ATGGCTGCAGGTTCAGCACTGACATCCCCTCTCATCCTGGCCCTGGTCTGCGCCCTGGCTGCCGTGGCTTACGGCATCTG
GGCCAGGGGCTGGATTCTTGCCCAAGACCCGGGCAATGCCCGCATGCAGGAGATCGCGGCCGCCATCCAGGCCGGCGCTG
CCGCTTACCTGGCGCGCCAGTACAAGACCATTGCCATGGTGGGCCTGGTGCTGGCGGTTTTGATCGGCCTGTTTCTCGAT
ACCACCACGGCCGTCGGCTTTGTCCTGGGGGCCTTGCTCTCGGGCGCCTGTGGTTTCATCGGCATGAACGTCTCGGTGCG
CGCCAATGTGCGCACCGCGCAGGCCGCAACCGCAGGCATAGGCCCGGCGCTGACGGTGGCGTTTCGTGGCGGCGCGATCA
CCGGCATGCTGGTGGTCGGGCTGGGCCTGCTCGGCGTGACCGCCTGTTACTGGTTTCTGGCCGGCGGCAACCCCGCGCCC
ACGGGCCAACTGGCCGGTTTGCTCGATCCGCTGATCGGCTTCGCCTTTGGCTCGTCGCTGATTTCCATCTTTGCGCGCCT
GGGCGGCGGCATCTTCACCAAGGGCGCCGACGTGGGCGCCGACCTGGTGGGCAAGGTCGAGGCCGGCATCCCCGAAGACG
ACCCGCGCAACCCGGCGGTGATCGCCGACAACGTGGGCGACAACGTGGGTGACTGCGCGGGCATGGCGGCCGACCTGTTC
GAGACCTATGCCGTGACACTGATCGCCACCATGGTGCTGGGCGCATTGCTGGTCACCACCGCTGCGCCCGATGCCGTGGT
CTACCCGCTGGCATTGGGGGCCGTGTCCATCATCGCCTCGATCATCGGCTGCTGCTTCGTCAAAGCCACGCCCGGCATGA
GGAACGTGATGCCCGCGCTATACAAGGGCCTGGCGATTGCCGGCATTTTGTCGCTGATCGCGTTCTACTTCGTCACGCTC
TGGATCATGCCGGACAACGCCATCACCGCCACCGGCAGCCAGTTGCGGCTGTTTGGCGCCTGCGCCACCGGGCTGGTGTT
GACCGCAGCACTGGTGTGGATCACCGAGTACTACACCGGCACGCAGTATGCGCCGGTGCAGCATATCGCCCAGGCCTCGA
CCACCGGCCATGGCACGAACATCATCGCCGGCCTGGGCGTGTCGATGCGCTCGACCGCCTGGCCGGTGATTTTCGTCTGC
CTGGCCATCCTGTCGGCCTACCAACTCGCCGGCCTGTATGGCATTGCGGTGGCGGCCATGTCCATGCTGAGCATGGCCGG
CATCGTGGTGGCGCTGGACGCCTATGGCCCGATCACCGACAACGCCGGCGGCATTGCCGAAATGGCCGAATTGCCCAGCA
GCGTGCGCGACATCACCGACCCGCTCGACGCCGTGGGCAACACCACCAAGGCCGTGACCAAGGGCTACGCGATCGGCTCT
GCGGGCCTGGCCGCCCTGGTGCTGTTTGCCGACTACACCCACAAGCTCGAAAGCCATGGCCGCGCGGTCAGCTTCGAGCT
GAGCGACCCGCTGGTGATCGTGGGACTGTTCATCGGCGGCCTGATCCCCTACCTGTTCGGCGCCATGGCCATGCAAGCCG
TGGGCCGCGCCGCCGGTGCCGTGGTGGTCGAAGTGCGCCGCCAGTTCAGCACCATCGCGGGCATCATGGACGGCAGCGGC
AAGCCCGAATACGGCAAGGCCGTGGACATGCTGACCAGCGCCGCGATCAAGGAGATGGTCCTGCCCAGCCTGCTGCCGGT
GGTCGTGCCCATTGCCGTCGGTCTGCTGCTCGGCCCGAAGGCGCTGGGCGGCCTGCTGATGGGCACCATCGTCACCGGCC
TGTTCGTGGCCATCAGCATGTGCACCGGCGGCGGCGCCTGGGACAACGCCAAGAAGTACATCGAAGACGGCCACCATGGC
GGCAAGGGCAGCGAGGCGCACAAGGCGGCCGTGACCGGCGACACCGTGGGCGACCCCTACAAAGACACGGCAGGCCCGGC
GATCAACCCGCTGATCAAGATCATCAACATCGTGGCGCTGCTGATCGTGCCGCTGGTGGTCAGATTCCACGGCGGGTGA

Upstream 100 bases:

>100_bases
ATCGGCCCTGCTTGGGGCAGGGCACGAGGAAGCAACGCAACGGGGCCACCACCGATGCGTTGGCGCCCCACCGTGCAACA
CCCCCCCCAAGGAGAACCCA

Downstream 100 bases:

>100_bases
TGTGCAACGCCGCCCCCCAGGCCGCCTGCGGCCGCGCGCCCCCGAACGGGCGACGGGGGGCGGCGCCAGCGGCTTGGCGC
GGGCCGCGCCCGGCGCATGT

Product: membrane-bound proton-translocating pyrophosphatase

Products: NA

Alternate protein names: Membrane-bound proton-translocating pyrophosphatase; Pyrophosphate-energized inorganic pyrophosphatase; H(+)-PPase [H]

Number of amino acids: Translated: 692; Mature: 691

Protein sequence:

>692_residues
MAAGSALTSPLILALVCALAAVAYGIWARGWILAQDPGNARMQEIAAAIQAGAAAYLARQYKTIAMVGLVLAVLIGLFLD
TTTAVGFVLGALLSGACGFIGMNVSVRANVRTAQAATAGIGPALTVAFRGGAITGMLVVGLGLLGVTACYWFLAGGNPAP
TGQLAGLLDPLIGFAFGSSLISIFARLGGGIFTKGADVGADLVGKVEAGIPEDDPRNPAVIADNVGDNVGDCAGMAADLF
ETYAVTLIATMVLGALLVTTAAPDAVVYPLALGAVSIIASIIGCCFVKATPGMRNVMPALYKGLAIAGILSLIAFYFVTL
WIMPDNAITATGSQLRLFGACATGLVLTAALVWITEYYTGTQYAPVQHIAQASTTGHGTNIIAGLGVSMRSTAWPVIFVC
LAILSAYQLAGLYGIAVAAMSMLSMAGIVVALDAYGPITDNAGGIAEMAELPSSVRDITDPLDAVGNTTKAVTKGYAIGS
AGLAALVLFADYTHKLESHGRAVSFELSDPLVIVGLFIGGLIPYLFGAMAMQAVGRAAGAVVVEVRRQFSTIAGIMDGSG
KPEYGKAVDMLTSAAIKEMVLPSLLPVVVPIAVGLLLGPKALGGLLMGTIVTGLFVAISMCTGGGAWDNAKKYIEDGHHG
GKGSEAHKAAVTGDTVGDPYKDTAGPAINPLIKIINIVALLIVPLVVRFHGG

Sequences:

>Translated_692_residues
MAAGSALTSPLILALVCALAAVAYGIWARGWILAQDPGNARMQEIAAAIQAGAAAYLARQYKTIAMVGLVLAVLIGLFLD
TTTAVGFVLGALLSGACGFIGMNVSVRANVRTAQAATAGIGPALTVAFRGGAITGMLVVGLGLLGVTACYWFLAGGNPAP
TGQLAGLLDPLIGFAFGSSLISIFARLGGGIFTKGADVGADLVGKVEAGIPEDDPRNPAVIADNVGDNVGDCAGMAADLF
ETYAVTLIATMVLGALLVTTAAPDAVVYPLALGAVSIIASIIGCCFVKATPGMRNVMPALYKGLAIAGILSLIAFYFVTL
WIMPDNAITATGSQLRLFGACATGLVLTAALVWITEYYTGTQYAPVQHIAQASTTGHGTNIIAGLGVSMRSTAWPVIFVC
LAILSAYQLAGLYGIAVAAMSMLSMAGIVVALDAYGPITDNAGGIAEMAELPSSVRDITDPLDAVGNTTKAVTKGYAIGS
AGLAALVLFADYTHKLESHGRAVSFELSDPLVIVGLFIGGLIPYLFGAMAMQAVGRAAGAVVVEVRRQFSTIAGIMDGSG
KPEYGKAVDMLTSAAIKEMVLPSLLPVVVPIAVGLLLGPKALGGLLMGTIVTGLFVAISMCTGGGAWDNAKKYIEDGHHG
GKGSEAHKAAVTGDTVGDPYKDTAGPAINPLIKIINIVALLIVPLVVRFHGG
>Mature_691_residues
AAGSALTSPLILALVCALAAVAYGIWARGWILAQDPGNARMQEIAAAIQAGAAAYLARQYKTIAMVGLVLAVLIGLFLDT
TTAVGFVLGALLSGACGFIGMNVSVRANVRTAQAATAGIGPALTVAFRGGAITGMLVVGLGLLGVTACYWFLAGGNPAPT
GQLAGLLDPLIGFAFGSSLISIFARLGGGIFTKGADVGADLVGKVEAGIPEDDPRNPAVIADNVGDNVGDCAGMAADLFE
TYAVTLIATMVLGALLVTTAAPDAVVYPLALGAVSIIASIIGCCFVKATPGMRNVMPALYKGLAIAGILSLIAFYFVTLW
IMPDNAITATGSQLRLFGACATGLVLTAALVWITEYYTGTQYAPVQHIAQASTTGHGTNIIAGLGVSMRSTAWPVIFVCL
AILSAYQLAGLYGIAVAAMSMLSMAGIVVALDAYGPITDNAGGIAEMAELPSSVRDITDPLDAVGNTTKAVTKGYAIGSA
GLAALVLFADYTHKLESHGRAVSFELSDPLVIVGLFIGGLIPYLFGAMAMQAVGRAAGAVVVEVRRQFSTIAGIMDGSGK
PEYGKAVDMLTSAAIKEMVLPSLLPVVVPIAVGLLLGPKALGGLLMGTIVTGLFVAISMCTGGGAWDNAKKYIEDGHHGG
KGSEAHKAAVTGDTVGDPYKDTAGPAINPLIKIINIVALLIVPLVVRFHGG

Specific function: Proton pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for proton movement across the membrane. Generates a proton motive force [H]

COG id: COG3808

COG function: function code C; Inorganic pyrophosphatase

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the H(+)-translocating pyrophosphatase (TC 3.A.10) family. K(+)-insensitive subfamily [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004131 [H]

Pfam domain/function: PF03030 H_PPase [H]

EC number: =3.6.1.1 [H]

Molecular weight: Translated: 70197; Mature: 70066

Theoretical pI: Translated: 6.10; Mature: 6.10

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAAGSALTSPLILALVCALAAVAYGIWARGWILAQDPGNARMQEIAAAIQAGAAAYLARQ
CCCCCHHHHHHHHHHHHHHHHHHHHHHHCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHH
YKTIAMVGLVLAVLIGLFLDTTTAVGFVLGALLSGACGFIGMNVSVRANVRTAQAATAGI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHEECCEEEEECCHHHHHHHCCC
GPALTVAFRGGAITGMLVVGLGLLGVTACYWFLAGGNPAPTGQLAGLLDPLIGFAFGSSL
CHHEEEEECCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHH
ISIFARLGGGIFTKGADVGADLVGKVEAGIPEDDPRNPAVIADNVGDNVGDCAGMAADLF
HHHHHHHCCCEEECCCCCCHHHHHHHHCCCCCCCCCCCEEEECCCCCCHHHHHHHHHHHH
ETYAVTLIATMVLGALLVTTAAPDAVVYPLALGAVSIIASIIGCCFVKATPGMRNVMPAL
HHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHH
YKGLAIAGILSLIAFYFVTLWIMPDNAITATGSQLRLFGACATGLVLTAALVWITEYYTG
HHHHHHHHHHHHHHHHHHHHHCCCCCCEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHCC
TQYAPVQHIAQASTTGHGTNIIAGLGVSMRSTAWPVIFVCLAILSAYQLAGLYGIAVAAM
CCCCHHHHHHHHCCCCCCCCCCEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SMLSMAGIVVALDAYGPITDNAGGIAEMAELPSSVRDITDPLDAVGNTTKAVTKGYAIGS
HHHHHHHHHEEEECCCCCCCCCCCHHHHHHCHHHHHHHHHHHHHHCCCHHHHHHCCCCCH
AGLAALVLFADYTHKLESHGRAVSFELSDPLVIVGLFIGGLIPYLFGAMAMQAVGRAAGA
HHHHHHHHHHHHHHHHHHCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VVVEVRRQFSTIAGIMDGSGKPEYGKAVDMLTSAAIKEMVLPSLLPVVVPIAVGLLLGPK
HHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHH
ALGGLLMGTIVTGLFVAISMCTGGGAWDNAKKYIEDGHHGGKGSEAHKAAVTGDTVGDPY
HHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHCCCCCCCCCCCCHHEECCCCCCCCC
KDTAGPAINPLIKIINIVALLIVPLVVRFHGG
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
AAGSALTSPLILALVCALAAVAYGIWARGWILAQDPGNARMQEIAAAIQAGAAAYLARQ
CCCCHHHHHHHHHHHHHHHHHHHHHHHCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHH
YKTIAMVGLVLAVLIGLFLDTTTAVGFVLGALLSGACGFIGMNVSVRANVRTAQAATAGI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHEECCEEEEECCHHHHHHHCCC
GPALTVAFRGGAITGMLVVGLGLLGVTACYWFLAGGNPAPTGQLAGLLDPLIGFAFGSSL
CHHEEEEECCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHH
ISIFARLGGGIFTKGADVGADLVGKVEAGIPEDDPRNPAVIADNVGDNVGDCAGMAADLF
HHHHHHHCCCEEECCCCCCHHHHHHHHCCCCCCCCCCCEEEECCCCCCHHHHHHHHHHHH
ETYAVTLIATMVLGALLVTTAAPDAVVYPLALGAVSIIASIIGCCFVKATPGMRNVMPAL
HHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHH
YKGLAIAGILSLIAFYFVTLWIMPDNAITATGSQLRLFGACATGLVLTAALVWITEYYTG
HHHHHHHHHHHHHHHHHHHHHCCCCCCEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHCC
TQYAPVQHIAQASTTGHGTNIIAGLGVSMRSTAWPVIFVCLAILSAYQLAGLYGIAVAAM
CCCCHHHHHHHHCCCCCCCCCCEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SMLSMAGIVVALDAYGPITDNAGGIAEMAELPSSVRDITDPLDAVGNTTKAVTKGYAIGS
HHHHHHHHHEEEECCCCCCCCCCCHHHHHHCHHHHHHHHHHHHHHCCCHHHHHHCCCCCH
AGLAALVLFADYTHKLESHGRAVSFELSDPLVIVGLFIGGLIPYLFGAMAMQAVGRAAGA
HHHHHHHHHHHHHHHHHHCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VVVEVRRQFSTIAGIMDGSGKPEYGKAVDMLTSAAIKEMVLPSLLPVVVPIAVGLLLGPK
HHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHH
ALGGLLMGTIVTGLFVAISMCTGGGAWDNAKKYIEDGHHGGKGSEAHKAAVTGDTVGDPY
HHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHCCCCCCCCCCCCHHEECCCCCCCCC
KDTAGPAINPLIKIINIVALLIVPLVVRFHGG
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA