Click here to switch to the map view.

The map label for this gene is ligC [H]

Identifier: 121639647

GI number: 121639647

Start: 4155326

End: 4156402

Strand: Direct

Name: ligC [H]

Synonym: BCG_3791

Alternate gene names: 121639647

Gene position: 4155326-4156402 (Clockwise)

Preceding gene: 121639645

Following gene: 121639648

Centisome position: 94.99

GC content: 64.72

Gene sequence:

>1077_bases
ATGCAGTTACCCGTCATGCCGCCGGTGTCGCCGATGCTGGCCAAATCGGTCACCGCAATCCCGCCGGACGCGTCGTATGA
ACCCAAATGGGACGGATTCCGCTCCATCTGCTTTCGCGACGGTGATCAGGTCGAACTGGGTAGCCGCAACGAGCGGCCGA
TGACCCGCTACTTCCCCGAGCTGGTCGCCGCGATCAGGGCCGAGCTGCCGCATCGCTGTGTGATCGACGGGGAGATCATC
ATCGCCACCGACCACGGCTTGGACTTCGAGGCGCTGCAACAGCGCATCCATCCTGCCGAGTCGAGGGTGCGAATGCTTGC
CGACCGCACACCAGCCTCCTTCATCGCATTCGACCTGCTGGCCCTCGGCGACGACGACTACACCGGGCGACCGTTCAGCG
AAAGACGAGCCGCTCTGGTCGATGCCGTAACTGGTTCGGGGGCCGACGCTGACCTGTCGATCCACGTCACCCCGGCAACC
ACCGACATGGCGACCGCACAACGATGGTTCTCCGAGTTCGAGGGGGCCGGTCTAGACGGTGTCATCGCCAAACCGCCGCA
CATCACCTATCAACCGGACAAACGCGTTATGTTCAAGATCAAACACCTGCGGACCGCCGATTGCGTGGTGGCCGGCTACC
GGGTGCACAAGTCCGGCAGTGACGCGATCGGCTCACTGCTGCTAGGGCTTTACCAGGAGGACGGCCAACTCGCGTCGGTC
GGCGTGATCGGCGCGTTCCCCATGGCCGAACGACGCCGGCTATTAACCGAGCTGCAGCCGCTGGTCACCAGCTTCGACGA
CCACCCATGGAACTGGGCCGCCCACGTTGCCGGCCAGCGCACCCCACGTAAGAACGAGTTCTCCCGCTGGAATGTCGGCA
AAGACCTGTCGTTCGTGCCGCTGCGACCCGAGCGGGTGGTCGAGGTCCGCTACGACCACATGGAAGGCGCGCGGTTCCGC
CACACCGCACAGTTCAACCGGTGGCGCCCCGACCGCGACCCACGCTCATGCAGCTATGCCCAGCTCGAACGCCCGCTCAC
CGTCAGCCTCTCCGACATTGTGCCGGGCCTACGCTAA

Upstream 100 bases:

>100_bases
GTCCGGGCTAGTCAACCGCACCGCGATGCCGTCGACGTCGAGTTCCTCAGCTGCCGCCGCCATATCGGAATTCCAGCATG
CCGCACGCAAGAATGAGCAC

Downstream 100 bases:

>100_bases
GGTGCGACCCTCTTCGGTCAGTTGATCCCCGGTGGGCCGATCGGCTCGGGCGCCACATCCGGGTCGGTTCGTTGCGTTCG
GCCGCGTAACATCTGCGGCA

Product: ATP-dependent DNA ligase

Products: NA

Alternate protein names: Polydeoxyribonucleotide synthase [ATP] [H]

Number of amino acids: Translated: 358; Mature: 358

Protein sequence:

>358_residues
MQLPVMPPVSPMLAKSVTAIPPDASYEPKWDGFRSICFRDGDQVELGSRNERPMTRYFPELVAAIRAELPHRCVIDGEII
IATDHGLDFEALQQRIHPAESRVRMLADRTPASFIAFDLLALGDDDYTGRPFSERRAALVDAVTGSGADADLSIHVTPAT
TDMATAQRWFSEFEGAGLDGVIAKPPHITYQPDKRVMFKIKHLRTADCVVAGYRVHKSGSDAIGSLLLGLYQEDGQLASV
GVIGAFPMAERRRLLTELQPLVTSFDDHPWNWAAHVAGQRTPRKNEFSRWNVGKDLSFVPLRPERVVEVRYDHMEGARFR
HTAQFNRWRPDRDPRSCSYAQLERPLTVSLSDIVPGLR

Sequences:

>Translated_358_residues
MQLPVMPPVSPMLAKSVTAIPPDASYEPKWDGFRSICFRDGDQVELGSRNERPMTRYFPELVAAIRAELPHRCVIDGEII
IATDHGLDFEALQQRIHPAESRVRMLADRTPASFIAFDLLALGDDDYTGRPFSERRAALVDAVTGSGADADLSIHVTPAT
TDMATAQRWFSEFEGAGLDGVIAKPPHITYQPDKRVMFKIKHLRTADCVVAGYRVHKSGSDAIGSLLLGLYQEDGQLASV
GVIGAFPMAERRRLLTELQPLVTSFDDHPWNWAAHVAGQRTPRKNEFSRWNVGKDLSFVPLRPERVVEVRYDHMEGARFR
HTAQFNRWRPDRDPRSCSYAQLERPLTVSLSDIVPGLR
>Mature_358_residues
MQLPVMPPVSPMLAKSVTAIPPDASYEPKWDGFRSICFRDGDQVELGSRNERPMTRYFPELVAAIRAELPHRCVIDGEII
IATDHGLDFEALQQRIHPAESRVRMLADRTPASFIAFDLLALGDDDYTGRPFSERRAALVDAVTGSGADADLSIHVTPAT
TDMATAQRWFSEFEGAGLDGVIAKPPHITYQPDKRVMFKIKHLRTADCVVAGYRVHKSGSDAIGSLLLGLYQEDGQLASV
GVIGAFPMAERRRLLTELQPLVTSFDDHPWNWAAHVAGQRTPRKNEFSRWNVGKDLSFVPLRPERVVEVRYDHMEGARFR
HTAQFNRWRPDRDPRSCSYAQLERPLTVSLSDIVPGLR

Specific function: DNA ligase that seals nicks in double-stranded DNA during DNA replication, DNA recombination and DNA repair [H]

COG id: COG1793

COG function: function code L; ATP-dependent DNA ligase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ATP-dependent DNA ligase family [H]

Homologues:

Organism=Drosophila melanogaster, GI85815841, Length=265, Percent_Identity=27.5471698113208, Blast_Score=70, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR022865
- InterPro:   IPR000977
- InterPro:   IPR012309
- InterPro:   IPR012310
- InterPro:   IPR016059
- InterPro:   IPR012308
- InterPro:   IPR012340
- InterPro:   IPR016027 [H]

Pfam domain/function: PF04679 DNA_ligase_A_C; PF01068 DNA_ligase_A_M; PF04675 DNA_ligase_A_N [H]

EC number: =6.5.1.1 [H]

Molecular weight: Translated: 40141; Mature: 40141

Theoretical pI: Translated: 6.91; Mature: 6.91

Prosite motif: PS50160 DNA_LIGASE_A3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQLPVMPPVSPMLAKSVTAIPPDASYEPKWDGFRSICFRDGDQVELGSRNERPMTRYFPE
CCCCCCCCCCHHHHHHCCCCCCCCCCCCCCCHHHHHHHCCCCEEECCCCCCCCHHHHHHH
LVAAIRAELPHRCVIDGEIIIATDHGLDFEALQQRIHPAESRVRMLADRTPASFIAFDLL
HHHHHHHCCCCEEEECCEEEEEECCCCCHHHHHHHCCCHHHHHHHHHCCCCHHHHHHHHH
ALGDDDYTGRPFSERRAALVDAVTGSGADADLSIHVTPATTDMATAQRWFSEFEGAGLDG
HCCCCCCCCCCHHHHHHHHHHHHCCCCCCCEEEEEEECCCHHHHHHHHHHHHHCCCCCCC
VIAKPPHITYQPDKRVMFKIKHLRTADCVVAGYRVHKSGSDAIGSLLLGLYQEDGQLASV
EECCCCCCEECCCHHEEEEEHHCCCCHHEEECEEEECCCCHHHHHHHHHHHHCCCCEEEE
GVIGAFPMAERRRLLTELQPLVTSFDDHPWNWAAHVAGQRTPRKNEFSRWNVGKDLSFVP
EEEECCCHHHHHHHHHHHHHHHHCCCCCCCCHHHHHCCCCCCCCCCCCCCCCCCCCEEEC
LRPERVVEVRYDHMEGARFRHTAQFNRWRPDRDPRSCSYAQLERPLTVSLSDIVPGLR
CCCHHEEEEEECCCCCCCHHHHHHHHCCCCCCCCCCCCHHHHCCCCEEEHHHHCCCCC
>Mature Secondary Structure
MQLPVMPPVSPMLAKSVTAIPPDASYEPKWDGFRSICFRDGDQVELGSRNERPMTRYFPE
CCCCCCCCCCHHHHHHCCCCCCCCCCCCCCCHHHHHHHCCCCEEECCCCCCCCHHHHHHH
LVAAIRAELPHRCVIDGEIIIATDHGLDFEALQQRIHPAESRVRMLADRTPASFIAFDLL
HHHHHHHCCCCEEEECCEEEEEECCCCCHHHHHHHCCCHHHHHHHHHCCCCHHHHHHHHH
ALGDDDYTGRPFSERRAALVDAVTGSGADADLSIHVTPATTDMATAQRWFSEFEGAGLDG
HCCCCCCCCCCHHHHHHHHHHHHCCCCCCCEEEEEEECCCHHHHHHHHHHHHHCCCCCCC
VIAKPPHITYQPDKRVMFKIKHLRTADCVVAGYRVHKSGSDAIGSLLLGLYQEDGQLASV
EECCCCCCEECCCHHEEEEEHHCCCCHHEEECEEEECCCCHHHHHHHHHHHHCCCCEEEE
GVIGAFPMAERRRLLTELQPLVTSFDDHPWNWAAHVAGQRTPRKNEFSRWNVGKDLSFVP
EEEECCCHHHHHHHHHHHHHHHHCCCCCCCCHHHHHCCCCCCCCCCCCCCCCCCCCEEEC
LRPERVVEVRYDHMEGARFRHTAQFNRWRPDRDPRSCSYAQLERPLTVSLSDIVPGLR
CCCHHEEEEEECCCCCCCHHHHHHHHCCCCCCCCCCCCHHHHCCCCEEEHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA