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The map label for this gene is ubiE [C]

Identifier: 121639645

GI number: 121639645

Start: 4151853

End: 4154183

Strand: Direct

Name: ubiE [C]

Synonym: BCG_3789

Alternate gene names: 121639645

Gene position: 4151853-4154183 (Clockwise)

Preceding gene: 121639644

Following gene: 121639647

Centisome position: 94.91

GC content: 65.04

Gene sequence:

>2331_bases
ATGTTCGTCGAATACACCAAGAGCATCTGCCCCGTCTGCAAGGTCGTGGTCGACGCCCAGGTCAATATCCGCCACGACAA
GGTGTATTTGCGTAAGCGCTGCCGCGAGCACGGAAGTTTCGAGGCCCTGGTGTACGGGGATGCCCAGATGTATTTGGAAT
CAGCACGATTCAACAAACCGGGCACCTTTCCGCTGCGGTTTCAGACCGAGGTGCGCGACGGCTGTCCCAGTGACTGCGGG
CTGTGCCCGGACCACAAGCAACACGCCTGCCTGGGGTTGATCGAGGTCAACACACACTGCAACCTGGACTGCCCGATCTG
TTTCGCCGACTCTGGCCACCAACCCGACGGCTACGCCATCACCGCGGCGCAGTGTGAACGGATGCTCGACACGCTCGTTG
CCGCCGAGGGTGAACCCGAAGTGGTGATGTTCTCCGGTGGCGAACCGACCATCCACAAACAACTCCTCGAGTTCGTCGAC
GCCGCCCAGGCCCGCCCGGTCAAGACCATCATCATCAACACCAACGGCATCCGGCTGGCCTCCGACCGGCGATTCGTCGA
CCAGCTCGCCACCCGCAACCGTCCCGGCCACCCCGTGCACATCTACCTGCAGTTCGACGGCCTGGACGAGGCAACACATC
GTCGAATCCGGGGCCACGATCTGCGGGACGTAAAGCAGCGGGCCCTGGACAACTGCGCCGCGGCGGGCCTGACCGTCAGC
CTGGTGGCCGCGGTGGAACGCGGCCTCAACGAGCACGAGCTCGGCGCGGTCATCCGCCACGGCATGGCGCAGCCCGGAGT
GCAATCGGTGGTATTTCAGCCGGTCACCCACGCCGGCCGGCATGTGCAGTTCGACCCGCTGACCCGACTGACCAACTCCG
ACATCATCGCCTGCATCACCGCGCAACTGCCCGAATGGTTCAGGCCCGGTGACTTCTTTCCGGTGCCATGCTGCTTCCCC
AGCTGCCGATCGATCACCTACCTGCTCACCGACGGGGAGCATGTGGTCCCGATTCCGCGGCTGCTCAATGTCGAGGACTA
CCTCGACTACGTCTCCAACCGGGTGATCCCTGACCTGGCGATCCGCGAAGCCTTGGAGAACTTGTGGTCGGCGTCGGCGG
TGCCAGGCACCGACACCATGACCGCACAGCTACAGCGGGCTACCGCCGCCCTGAACTGCGCCGAGGGCTGCGGGATCAAC
CTGCCCGAGGCCCTCACGCACCTCACCGACCGGGTCTTCGCCATCGTCATCCAAGACTTCCAGGATCCCTACACCCTCAA
CGTCAAACAGCTGATGAAATGCTGCGTGCAACAGATCACCCCGGACGGACGGCTGATCCCGTTCTGCGCCTACAACTCGG
TCGGCTATCGAGAGCAGGTGCGTGAACAGCTCACCGGGGTACCGGTACCCGACATTGTGCCCAATGCCATCCCACTCGCC
GGGTTGCTGGCGGACGCACCACACGGATCAAAACAGGCCAATACCGGTGGGAGTATCGCCAGGCTCGCGGGGCCAACCCG
AGGTGCGCCGATGGCACTGCCACCACAGCAGATCAAAGCGTGTTGCGCCGACGCCTATTCCCGCGACATCGTCGCCTTGC
TACTCGGTGACTCCTTTCACCCGGGCGGCGCGACATTGACCCGTAGGTTGGCTGACCAACTCGGGCTGAGGTCGACAGGC
GACCCGCGGCGGGTCGCCGACATCGCCGCCGGGCCCGGCGCCTCCGCACGGCTGCTGGCCAGCGACTACGGTGTGGCTGT
CGACGGGGTCGACATCAGCGAGATCAACGTGAAGCGCGCCCAAGCCGCCGTCGCGCAAACCGGCCTGACCGAGCGGGTGC
GCTTCCACCTGGGCGACGCCGAATCAGTCCCGTTGCCCGACGACACATTCGACGCGCTGGTGTGCGAGTGCGCGTTCTGC
ACATTCCCGGACAAGAACGCCGCCGCCCAGCAGTTCGCTCGGATTCTGCGTCCTGGTGGCCTGGCCGGCATCACCGATGT
CACTGTCGGGGACGGCGGCCTGCCGGCGGAGCTGACCCCATTGGCCGCGTGGGTCGCCTGCATCGCCGACGCCCGAACCG
TCACCGACTACACCGACATCCTCGAAGGGGCCGGATTGCGCACCCGCCACATCGAGTCTCATGACGAGAGCCTGCTGGAC
ATGATCGACCGCATCGACGCGCGGATCACCGCCTTGCACGTCGCCGCACCGGAGATCCTCGCCGACAACGGCATTCGCCA
CGACTCGGTGCGCGATTTCACAGCGCTCGCACGCGCCGCGGTACAAACCGGACGAATCGGATACACGTTGATGATCGCGG
AAAAGCCGTGA

Upstream 100 bases:

>100_bases
CCCGATTGTTCGACCGCAGACACTGATCTATCGCGCAGGCGTTGCCGCATGGTGGACTAGCCCAATGACGCGGGCTGACG
GCAAGCGCGACCGTGACGAG

Downstream 100 bases:

>100_bases
TAATCCAGGAAATGTGGGACAGACCAATCGCATTTCCCGCATCTGAGGAGCGAGCCGCACCGCGTTACTTCGACGTGTTT
CCCCCCTTCAAGTCGGTATC

Product: putative transferase

Products: S-Adenosyl-L-Homocysteine; @OCTA02.txt*2- Polyprenyl-3-Methyl-6-Methoxy-1,4-Benzoquinol!; Menaquinol. [C]

Alternate protein names: NA

Number of amino acids: Translated: 776; Mature: 776

Protein sequence:

>776_residues
MFVEYTKSICPVCKVVVDAQVNIRHDKVYLRKRCREHGSFEALVYGDAQMYLESARFNKPGTFPLRFQTEVRDGCPSDCG
LCPDHKQHACLGLIEVNTHCNLDCPICFADSGHQPDGYAITAAQCERMLDTLVAAEGEPEVVMFSGGEPTIHKQLLEFVD
AAQARPVKTIIINTNGIRLASDRRFVDQLATRNRPGHPVHIYLQFDGLDEATHRRIRGHDLRDVKQRALDNCAAAGLTVS
LVAAVERGLNEHELGAVIRHGMAQPGVQSVVFQPVTHAGRHVQFDPLTRLTNSDIIACITAQLPEWFRPGDFFPVPCCFP
SCRSITYLLTDGEHVVPIPRLLNVEDYLDYVSNRVIPDLAIREALENLWSASAVPGTDTMTAQLQRATAALNCAEGCGIN
LPEALTHLTDRVFAIVIQDFQDPYTLNVKQLMKCCVQQITPDGRLIPFCAYNSVGYREQVREQLTGVPVPDIVPNAIPLA
GLLADAPHGSKQANTGGSIARLAGPTRGAPMALPPQQIKACCADAYSRDIVALLLGDSFHPGGATLTRRLADQLGLRSTG
DPRRVADIAAGPGASARLLASDYGVAVDGVDISEINVKRAQAAVAQTGLTERVRFHLGDAESVPLPDDTFDALVCECAFC
TFPDKNAAAQQFARILRPGGLAGITDVTVGDGGLPAELTPLAAWVACIADARTVTDYTDILEGAGLRTRHIESHDESLLD
MIDRIDARITALHVAAPEILADNGIRHDSVRDFTALARAAVQTGRIGYTLMIAEKP

Sequences:

>Translated_776_residues
MFVEYTKSICPVCKVVVDAQVNIRHDKVYLRKRCREHGSFEALVYGDAQMYLESARFNKPGTFPLRFQTEVRDGCPSDCG
LCPDHKQHACLGLIEVNTHCNLDCPICFADSGHQPDGYAITAAQCERMLDTLVAAEGEPEVVMFSGGEPTIHKQLLEFVD
AAQARPVKTIIINTNGIRLASDRRFVDQLATRNRPGHPVHIYLQFDGLDEATHRRIRGHDLRDVKQRALDNCAAAGLTVS
LVAAVERGLNEHELGAVIRHGMAQPGVQSVVFQPVTHAGRHVQFDPLTRLTNSDIIACITAQLPEWFRPGDFFPVPCCFP
SCRSITYLLTDGEHVVPIPRLLNVEDYLDYVSNRVIPDLAIREALENLWSASAVPGTDTMTAQLQRATAALNCAEGCGIN
LPEALTHLTDRVFAIVIQDFQDPYTLNVKQLMKCCVQQITPDGRLIPFCAYNSVGYREQVREQLTGVPVPDIVPNAIPLA
GLLADAPHGSKQANTGGSIARLAGPTRGAPMALPPQQIKACCADAYSRDIVALLLGDSFHPGGATLTRRLADQLGLRSTG
DPRRVADIAAGPGASARLLASDYGVAVDGVDISEINVKRAQAAVAQTGLTERVRFHLGDAESVPLPDDTFDALVCECAFC
TFPDKNAAAQQFARILRPGGLAGITDVTVGDGGLPAELTPLAAWVACIADARTVTDYTDILEGAGLRTRHIESHDESLLD
MIDRIDARITALHVAAPEILADNGIRHDSVRDFTALARAAVQTGRIGYTLMIAEKP
>Mature_776_residues
MFVEYTKSICPVCKVVVDAQVNIRHDKVYLRKRCREHGSFEALVYGDAQMYLESARFNKPGTFPLRFQTEVRDGCPSDCG
LCPDHKQHACLGLIEVNTHCNLDCPICFADSGHQPDGYAITAAQCERMLDTLVAAEGEPEVVMFSGGEPTIHKQLLEFVD
AAQARPVKTIIINTNGIRLASDRRFVDQLATRNRPGHPVHIYLQFDGLDEATHRRIRGHDLRDVKQRALDNCAAAGLTVS
LVAAVERGLNEHELGAVIRHGMAQPGVQSVVFQPVTHAGRHVQFDPLTRLTNSDIIACITAQLPEWFRPGDFFPVPCCFP
SCRSITYLLTDGEHVVPIPRLLNVEDYLDYVSNRVIPDLAIREALENLWSASAVPGTDTMTAQLQRATAALNCAEGCGIN
LPEALTHLTDRVFAIVIQDFQDPYTLNVKQLMKCCVQQITPDGRLIPFCAYNSVGYREQVREQLTGVPVPDIVPNAIPLA
GLLADAPHGSKQANTGGSIARLAGPTRGAPMALPPQQIKACCADAYSRDIVALLLGDSFHPGGATLTRRLADQLGLRSTG
DPRRVADIAAGPGASARLLASDYGVAVDGVDISEINVKRAQAAVAQTGLTERVRFHLGDAESVPLPDDTFDALVCECAFC
TFPDKNAAAQQFARILRPGGLAGITDVTVGDGGLPAELTPLAAWVACIADARTVTDYTDILEGAGLRTRHIESHDESLLD
MIDRIDARITALHVAAPEILADNGIRHDSVRDFTALARAAVQTGRIGYTLMIAEKP

Specific function: Methyltransferase Required For The Conversion Of Dimethylmenaquinone (Dmkh2) To Menaquinone (Mkh2) And The Conversion Of 2-Polyprenyl-6-Methoxy-1,4-Benzoquinol (Ddmqh2) To 2-Polyprenyl-3-Methyl-6-Methoxy-1,4-Benzoquinol (Dmqh2). [C]

COG id: COG1964

COG function: function code R; Predicted Fe-S oxidoreductases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006638
- InterPro:   IPR007197 [H]

Pfam domain/function: PF04055 Radical_SAM [H]

EC number: 2.1.1.- [C]

Molecular weight: Translated: 84134; Mature: 84134

Theoretical pI: Translated: 5.83; Mature: 5.83

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.5 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
3.5 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFVEYTKSICPVCKVVVDAQVNIRHDKVYLRKRCREHGSFEALVYGDAQMYLESARFNKP
CCCCHHHHHHHHHHHHHCCCEEEEHHHHHHHHHHHHCCCEEEEEECCHHHHHHHHCCCCC
GTFPLRFQTEVRDGCPSDCGLCPDHKQHACLGLIEVNTHCNLDCPICFADSGHQPDGYAI
CCCEEEEEHHHCCCCCCCCCCCCCCCCCCEEEEEEECCCCCCCCCEEECCCCCCCCCEEE
TAAQCERMLDTLVAAEGEPEVVMFSGGEPTIHKQLLEFVDAAQARPVKTIIINTNGIRLA
EHHHHHHHHHHHHHCCCCCCEEEECCCCCHHHHHHHHHHHHHCCCCEEEEEEECCCEEEE
SDRRFVDQLATRNRPGHPVHIYLQFDGLDEATHRRIRGHDLRDVKQRALDNCAAAGLTVS
CCHHHHHHHHHCCCCCCEEEEEEEECCCCHHHHHHHCCCCHHHHHHHHHHHHHHCCHHHH
LVAAVERGLNEHELGAVIRHGMAQPGVQSVVFQPVTHAGRHVQFDPLTRLTNSDIIACIT
HHHHHHHCCCHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCEEEECHHHHCCCCCEEEEEE
AQLPEWFRPGDFFPVPCCFPSCRSITYLLTDGEHVVPIPRLLNVEDYLDYVSNRVIPDLA
HHCHHHCCCCCCCCCCCCCCCCCCEEEEEECCCEEECCHHHCCHHHHHHHHHCCCCCHHH
IREALENLWSASAVPGTDTMTAQLQRATAALNCAEGCGINLPEALTHLTDRVFAIVIQDF
HHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHC
QDPYTLNVKQLMKCCVQQITPDGRLIPFCAYNSVGYREQVREQLTGVPVPDIVPNAIPLA
CCCEEECHHHHHHHHHHHCCCCCCEEEEEECCCCCHHHHHHHHHCCCCCCCCCCCCCCHH
GLLADAPHGSKQANTGGSIARLAGPTRGAPMALPPQQIKACCADAYSRDIVALLLGDSFH
HHHHCCCCCCCCCCCCCCCHHHCCCCCCCCCCCCHHHHHHHHHHHHHHCEEEEEECCCCC
PGGATLTRRLADQLGLRSTGDPRRVADIAAGPGASARLLASDYGVAVDGVDISEINVKRA
CCHHHHHHHHHHHHCCCCCCCCHHHHHHCCCCCCCCEEEECCCCEEECCCCHHHHHHHHH
QAAVAQTGLTERVRFHLGDAESVPLPDDTFDALVCECAFCTFPDKNAAAQQFARILRPGG
HHHHHHHCCHHHHHEECCCCCCCCCCCCHHHHHHHHHHHCCCCCCCHHHHHHHHHHCCCC
LAGITDVTVGDGGLPAELTPLAAWVACIADARTVTDYTDILEGAGLRTRHIESHDESLLD
CCCCEEEEECCCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCEECCCHHHHHHHH
MIDRIDARITALHVAAPEILADNGIRHDSVRDFTALARAAVQTGRIGYTLMIAEKP
HHHHHHHHEEEEEECCCHHHHCCCCCCCHHHHHHHHHHHHHHCCCCCEEEEEECCC
>Mature Secondary Structure
MFVEYTKSICPVCKVVVDAQVNIRHDKVYLRKRCREHGSFEALVYGDAQMYLESARFNKP
CCCCHHHHHHHHHHHHHCCCEEEEHHHHHHHHHHHHCCCEEEEEECCHHHHHHHHCCCCC
GTFPLRFQTEVRDGCPSDCGLCPDHKQHACLGLIEVNTHCNLDCPICFADSGHQPDGYAI
CCCEEEEEHHHCCCCCCCCCCCCCCCCCCEEEEEEECCCCCCCCCEEECCCCCCCCCEEE
TAAQCERMLDTLVAAEGEPEVVMFSGGEPTIHKQLLEFVDAAQARPVKTIIINTNGIRLA
EHHHHHHHHHHHHHCCCCCCEEEECCCCCHHHHHHHHHHHHHCCCCEEEEEEECCCEEEE
SDRRFVDQLATRNRPGHPVHIYLQFDGLDEATHRRIRGHDLRDVKQRALDNCAAAGLTVS
CCHHHHHHHHHCCCCCCEEEEEEEECCCCHHHHHHHCCCCHHHHHHHHHHHHHHCCHHHH
LVAAVERGLNEHELGAVIRHGMAQPGVQSVVFQPVTHAGRHVQFDPLTRLTNSDIIACIT
HHHHHHHCCCHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCEEEECHHHHCCCCCEEEEEE
AQLPEWFRPGDFFPVPCCFPSCRSITYLLTDGEHVVPIPRLLNVEDYLDYVSNRVIPDLA
HHCHHHCCCCCCCCCCCCCCCCCCEEEEEECCCEEECCHHHCCHHHHHHHHHCCCCCHHH
IREALENLWSASAVPGTDTMTAQLQRATAALNCAEGCGINLPEALTHLTDRVFAIVIQDF
HHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHC
QDPYTLNVKQLMKCCVQQITPDGRLIPFCAYNSVGYREQVREQLTGVPVPDIVPNAIPLA
CCCEEECHHHHHHHHHHHCCCCCCEEEEEECCCCCHHHHHHHHHCCCCCCCCCCCCCCHH
GLLADAPHGSKQANTGGSIARLAGPTRGAPMALPPQQIKACCADAYSRDIVALLLGDSFH
HHHHCCCCCCCCCCCCCCCHHHCCCCCCCCCCCCHHHHHHHHHHHHHHCEEEEEECCCCC
PGGATLTRRLADQLGLRSTGDPRRVADIAAGPGASARLLASDYGVAVDGVDISEINVKRA
CCHHHHHHHHHHHHCCCCCCCCHHHHHHCCCCCCCCEEEECCCCEEECCCCHHHHHHHHH
QAAVAQTGLTERVRFHLGDAESVPLPDDTFDALVCECAFCTFPDKNAAAQQFARILRPGG
HHHHHHHCCHHHHHEECCCCCCCCCCCCHHHHHHHHHHHCCCCCCCHHHHHHHHHHCCCC
LAGITDVTVGDGGLPAELTPLAAWVACIADARTVTDYTDILEGAGLRTRHIESHDESLLD
CCCCEEEEECCCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCEECCCHHHHHHHH
MIDRIDARITALHVAAPEILADNGIRHDSVRDFTALARAAVQTGRIGYTLMIAEKP
HHHHHHHHEEEEEECCCHHHHCCCCCCCHHHHHHHHHHHHHHCCCCCEEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: S-Adenosyl-L-Methionine; 2-Polyprenyl-6- Methoxy-1,4-Benzoquinol; Demethylmenaquinol [C]

Specific reaction: S-Adenosyl-L-Methionine + @OCTA02.txt*2-Polyprenyl-6- Methoxy-1,4-Benzoquinol! = S-Adenosyl-L-Homocysteine + 2- Polyprenyl-3-Methyl-6-Methoxy -1,4-Benzoquinol S-Adenosyl-L-Methionine + Demethylmenaquinol = S-Adenosyl-L-Homocysteine + Menaquinol. [C]

General reaction: Transferring one-carbon groups; Methyltransferases [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]