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The map label for this gene is yprA [H]

Identifier: 121639562

GI number: 121639562

Start: 4061802

End: 4064117

Strand: Direct

Name: yprA [H]

Synonym: BCG_3707

Alternate gene names: 121639562

Gene position: 4061802-4064117 (Clockwise)

Preceding gene: 121639558

Following gene: 121639563

Centisome position: 92.85

GC content: 68.39

Gene sequence:

>2316_bases
ATGGCGAGTTTCGGCAGCCACCTGCTGGCCGCAGCGGTCGCCGGGACCCCGCCGGGCGAGCGTCCGCTGCGCCACGTCGC
CGAGCTGCCACCGCAGGCCGGCCGGCCGCGCGGTTGGCCGGAGTGGGCCGAGCCCGACGTGGTGGATGCGTTTGCCGACC
GCGGCATCAGCTCGCCGTGGTCACACCAGGCTGAGGCCGCCGAGTTGGCGTACGCCGGCCGCCACGTGGTGATAGGCACC
GGCCCGGCGTCTGGAAAGTCGTTGGCCTATCAACTTCCCGTGCTCAACGCGCTGGCAACCGACTCCCGGGCGCGTGCGCT
GTATCTGTCGCCGACGAAGGCGCTCGGCCACGACCAGTTGCGCGCCGCACATGCGCTGGCGGCCGCGGTGCCACGGCTGG
CTGACGTCGCGCCGACGGCCTATGACGGCGACAGTCCCGACGAGGTGCGCCGCTTTGCCCGCGAGCGCTCCCGGTGGCTG
TTCTCCAACCCGGAGATGACACACCTATCGGTGCTTCGAAACCATGCGCGCTGGGCTGTGCTGTTGCGGAATCTCCGCTT
TGTGATCGTCGACGAATGCCATTACTACCGTGGTGTTTTCGGCTCGAATGTGGCGATGGTACTGCGCCGTTTACTACGGC
TGTGCGCGCGCTACTCTGCGCACCCGACGGTGATCTTCGCCAGCGCGACAACGGCCTCGCCGGGCGCGACGGCTGCCGAC
CTGATCGGCCAGCCGGTCGTGGAGGTCACCGAGGACGGCTCACCCCGGGGGGCTCGCACGGTGGCATTGTGGGAGCCCGC
GCTGCGGTCGGATGTGATCGGCGAGCACGGCGCCCCGGTGCGACGCTCCGCCGGTGCCGAGGCGGCCCGGGTGATGGCCG
ACCTGATCGTCGAGGGAGCGCAGACCTTGACGTTCGTCCGATCGCGGCGCGCGGCGGAACTGACTGCACTGGGTGCCCGG
GCGCGACTGGTCGACATTGCCCCGGAACTGTCGGACACGGTGGCGTCGTATCGGGCCGGTTATCTTGCCGAGGACCGTAG
CGCGCTGCACCAGGCCCTGGCCGAGGGCCAGCTGCGCGGGCTGGCTACCACCAACGCTTTGGAGTTGGGCGTTGATATCG
CCGGACTGGATGCGGTGGTGCTGGCTGGTTTTCCCGGGACGGTGGCCTCGTTCTGGCAGCAGGCGGGCCGGTCGGGCCGG
CGCGGCCAGGGCGCGCTGGTGGTGTTGATTGCCCGTGACGATCCGCTGGACACGTATTTGGTCCACCATCCCGCAGCATT
GTTGGACAAACCGGTCGAGCGCGTGGTGATCGATCCGGTTAACCCGCACCTGCTGGGTCCCCAATTGCTTTGTGCAGCAA
CAGAACTGCCTTTAGACGACGCCGAGGTCCGGTCCTGGGGCGCCGTTGAGGTGGCGGAGAGTCTGGTTGACGACGGGCTG
TTGCGGCGCCGGAACGGCAGGTACTTTCCGGCGCCCGGGGTGAAACCGCATGCCGCCGTGGATGTCCGGGGGGCTATCGG
TGGCCAGATCGTCATCGTGGAGGCCGGAACCGGGCGGCTCTTGGGCAGCGTGGGCGTCGGTCAGGCCCCGGCCGCAGCGC
ACCCAGGCGCGGTGTACCTGCACCAGGGCGAGACCTACGTCGTTGACTCGCTGGATTTCCAGGACGGAATCGCCTTCGTG
CACGCCGAGGATCCCGGCTATGCCACGTTCGCGCGAGAGGTCACCGACATCGCGGTCACCGGCACCGGCGAGCGGTTGGT
CTTCGGGCCCGTTGCTTTGGGTTTGGTGCCGGTGACTGTCACCAATCACGTCGTCGGCTACCTGCGCCGCCAGCTGTCCG
GGGAGGTGCTGGACTTCGTGGAGCTGGACATGCCGGAACATACCTTGCCCACAACCGCGGTCATGTACACAATCACTTCG
GATGCATTGGTCCGCAGCGGTATTGAGGCCACACGGATTCCCGGGTCGTTGCACGCCGCCGAACACGCGGCCATCGGGCT
GCTGCCGCTGGTGGCCAGCTGCGACCGCGACGATATCGGCGGCATGTCCACAGCGACCGGGCCCGAGGGGCTGCCCAGTG
TCTTTGTCTACGACGGCTATCCGGGTGGAGCCGGATTCGCCGAACGCGGCTTTCGCCGGGCCCGCACCTGGCTGGGCGCC
ACCGCGGAGGCCATCGAAGCCTGCGAATGCCCCAGTGGGTGTCCATCGTGTGTGCAATCCCCCAAGTGCGGCAATGGCAA
CGACCCGTTAGACAAGGCGGGCGCGGTGCGGGTGCTGCGGCTGGTGCTCGCCGAGTTAAGTGAGGAATCACCGTGA

Upstream 100 bases:

>100_bases
TTTGACACGAACACAGAAGCTGCGACCGCCAATCAGTCAATCATGTTCATCGCGTCGGCAACAGCCTCTGGGTGTGGACG
GAGCTACGAAGGGTCCGCAA

Downstream 100 bases:

>100_bases
GCAGCCCAGCGTTCCGGCGTTGTCGGGCAAAGCGGGGTCGTCGTCTTAGCCGATGTGATGCACTTGACATCAGTGTCTTC
GGCCTATCACGTAGTGGTCG

Product: putative helicase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 771; Mature: 770

Protein sequence:

>771_residues
MASFGSHLLAAAVAGTPPGERPLRHVAELPPQAGRPRGWPEWAEPDVVDAFADRGISSPWSHQAEAAELAYAGRHVVIGT
GPASGKSLAYQLPVLNALATDSRARALYLSPTKALGHDQLRAAHALAAAVPRLADVAPTAYDGDSPDEVRRFARERSRWL
FSNPEMTHLSVLRNHARWAVLLRNLRFVIVDECHYYRGVFGSNVAMVLRRLLRLCARYSAHPTVIFASATTASPGATAAD
LIGQPVVEVTEDGSPRGARTVALWEPALRSDVIGEHGAPVRRSAGAEAARVMADLIVEGAQTLTFVRSRRAAELTALGAR
ARLVDIAPELSDTVASYRAGYLAEDRSALHQALAEGQLRGLATTNALELGVDIAGLDAVVLAGFPGTVASFWQQAGRSGR
RGQGALVVLIARDDPLDTYLVHHPAALLDKPVERVVIDPVNPHLLGPQLLCAATELPLDDAEVRSWGAVEVAESLVDDGL
LRRRNGRYFPAPGVKPHAAVDVRGAIGGQIVIVEAGTGRLLGSVGVGQAPAAAHPGAVYLHQGETYVVDSLDFQDGIAFV
HAEDPGYATFAREVTDIAVTGTGERLVFGPVALGLVPVTVTNHVVGYLRRQLSGEVLDFVELDMPEHTLPTTAVMYTITS
DALVRSGIEATRIPGSLHAAEHAAIGLLPLVASCDRDDIGGMSTATGPEGLPSVFVYDGYPGGAGFAERGFRRARTWLGA
TAEAIEACECPSGCPSCVQSPKCGNGNDPLDKAGAVRVLRLVLAELSEESP

Sequences:

>Translated_771_residues
MASFGSHLLAAAVAGTPPGERPLRHVAELPPQAGRPRGWPEWAEPDVVDAFADRGISSPWSHQAEAAELAYAGRHVVIGT
GPASGKSLAYQLPVLNALATDSRARALYLSPTKALGHDQLRAAHALAAAVPRLADVAPTAYDGDSPDEVRRFARERSRWL
FSNPEMTHLSVLRNHARWAVLLRNLRFVIVDECHYYRGVFGSNVAMVLRRLLRLCARYSAHPTVIFASATTASPGATAAD
LIGQPVVEVTEDGSPRGARTVALWEPALRSDVIGEHGAPVRRSAGAEAARVMADLIVEGAQTLTFVRSRRAAELTALGAR
ARLVDIAPELSDTVASYRAGYLAEDRSALHQALAEGQLRGLATTNALELGVDIAGLDAVVLAGFPGTVASFWQQAGRSGR
RGQGALVVLIARDDPLDTYLVHHPAALLDKPVERVVIDPVNPHLLGPQLLCAATELPLDDAEVRSWGAVEVAESLVDDGL
LRRRNGRYFPAPGVKPHAAVDVRGAIGGQIVIVEAGTGRLLGSVGVGQAPAAAHPGAVYLHQGETYVVDSLDFQDGIAFV
HAEDPGYATFAREVTDIAVTGTGERLVFGPVALGLVPVTVTNHVVGYLRRQLSGEVLDFVELDMPEHTLPTTAVMYTITS
DALVRSGIEATRIPGSLHAAEHAAIGLLPLVASCDRDDIGGMSTATGPEGLPSVFVYDGYPGGAGFAERGFRRARTWLGA
TAEAIEACECPSGCPSCVQSPKCGNGNDPLDKAGAVRVLRLVLAELSEESP
>Mature_770_residues
ASFGSHLLAAAVAGTPPGERPLRHVAELPPQAGRPRGWPEWAEPDVVDAFADRGISSPWSHQAEAAELAYAGRHVVIGTG
PASGKSLAYQLPVLNALATDSRARALYLSPTKALGHDQLRAAHALAAAVPRLADVAPTAYDGDSPDEVRRFARERSRWLF
SNPEMTHLSVLRNHARWAVLLRNLRFVIVDECHYYRGVFGSNVAMVLRRLLRLCARYSAHPTVIFASATTASPGATAADL
IGQPVVEVTEDGSPRGARTVALWEPALRSDVIGEHGAPVRRSAGAEAARVMADLIVEGAQTLTFVRSRRAAELTALGARA
RLVDIAPELSDTVASYRAGYLAEDRSALHQALAEGQLRGLATTNALELGVDIAGLDAVVLAGFPGTVASFWQQAGRSGRR
GQGALVVLIARDDPLDTYLVHHPAALLDKPVERVVIDPVNPHLLGPQLLCAATELPLDDAEVRSWGAVEVAESLVDDGLL
RRRNGRYFPAPGVKPHAAVDVRGAIGGQIVIVEAGTGRLLGSVGVGQAPAAAHPGAVYLHQGETYVVDSLDFQDGIAFVH
AEDPGYATFAREVTDIAVTGTGERLVFGPVALGLVPVTVTNHVVGYLRRQLSGEVLDFVELDMPEHTLPTTAVMYTITSD
ALVRSGIEATRIPGSLHAAEHAAIGLLPLVASCDRDDIGGMSTATGPEGLPSVFVYDGYPGGAGFAERGFRRARTWLGAT
AEAIEACECPSGCPSCVQSPKCGNGNDPLDKAGAVRVLRLVLAELSEESP

Specific function: Unknown

COG id: COG1205

COG function: function code R; Distinct helicase family with a unique C-terminal domain including a metal-binding cysteine cluster

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 helicase C-terminal domain [H]

Homologues:

Organism=Escherichia coli, GI1787942, Length=415, Percent_Identity=28.9156626506024, Blast_Score=69, Evalue=1e-12,
Organism=Saccharomyces cerevisiae, GI6320497, Length=778, Percent_Identity=31.1053984575836, Blast_Score=395, Evalue=1e-110,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014001
- InterPro:   IPR018973
- InterPro:   IPR011545
- InterPro:   IPR001650
- InterPro:   IPR014021 [H]

Pfam domain/function: PF00270 DEAD; PF09369 DUF1998; PF00271 Helicase_C [H]

EC number: 3.6.1.- [C]

Molecular weight: Translated: 81453; Mature: 81322

Theoretical pI: Translated: 6.03; Mature: 6.03

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MASFGSHLLAAAVAGTPPGERPLRHVAELPPQAGRPRGWPEWAEPDVVDAFADRGISSPW
CCCCHHHHHHHHHCCCCCCHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHCCCCCCC
SHQAEAAELAYAGRHVVIGTGPASGKSLAYQLPVLNALATDSRARALYLSPTKALGHDQL
CCCHHHHHHHHCCCEEEEECCCCCCCCEEEECCHHHHHHCCCCCEEEEECCHHHCCHHHH
RAAHALAAAVPRLADVAPTAYDGDSPDEVRRFARERSRWLFSNPEMTHLSVLRNHARWAV
HHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHCCEEECCCCHHHHHHHHHHHHHHH
LLRNLRFVIVDECHYYRGVFGSNVAMVLRRLLRLCARYSAHPTVIFASATTASPGATAAD
HHHCCCEEEEECHHHHHCCCCCCHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCCHHHH
LIGQPVVEVTEDGSPRGARTVALWEPALRSDVIGEHGAPVRRSAGAEAARVMADLIVEGA
HHCCCCEEECCCCCCCCCEEEEEECHHHHHHHCCCCCCCCHHHCCHHHHHHHHHHHHHHH
QTLTFVRSRRAAELTALGARARLVDIAPELSDTVASYRAGYLAEDRSALHQALAEGQLRG
HHHHHHHHHHHHHHHHHCCCCEEEECCCHHHHHHHHHHCCCCHHHHHHHHHHHHHCHHCC
LATTNALELGVDIAGLDAVVLAGFPGTVASFWQQAGRSGRRGQGALVVLIARDDPLDTYL
CCCCCHHHHCCEEECCCEEEEECCCHHHHHHHHHHCCCCCCCCCEEEEEEECCCCCCHHH
VHHPAALLDKPVERVVIDPVNPHLLGPQLLCAATELPLDDAEVRSWGAVEVAESLVDDGL
HHCCHHHHCCCCHHEEECCCCCCCCCCHHHHHHHCCCCCCHHHHCCCHHHHHHHHHHHHH
LRRRNGRYFPAPGVKPHAAVDVRGAIGGQIVIVEAGTGRLLGSVGVGQAPAAAHPGAVYL
HHHCCCCCCCCCCCCCCCEEEECCCCCCEEEEEECCCCCEEECCCCCCCCCCCCCCEEEE
HQGETYVVDSLDFQDGIAFVHAEDPGYATFAREVTDIAVTGTGERLVFGPVALGLVPVTV
ECCCEEEEECCCCCCCEEEEEECCCCHHHHHHHHHEEEEECCCCEEEECHHHHHHEEHHH
TNHVVGYLRRQLSGEVLDFVELDMPEHTLPTTAVMYTITSDALVRSGIEATRIPGSLHAA
HHHHHHHHHHHHCCHHHHHHHCCCCCCCCCCEEEEEEECHHHHHHCCCCHHCCCCCHHHH
EHAAIGLLPLVASCDRDDIGGMSTATGPEGLPSVFVYDGYPGGAGFAERGFRRARTWLGA
HHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCEEEEECCCCCCCCHHHHHHHHHHHHHCC
TAEAIEACECPSGCPSCVQSPKCGNGNDPLDKAGAVRVLRLVLAELSEESP
CHHHHHHHCCCCCCHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
ASFGSHLLAAAVAGTPPGERPLRHVAELPPQAGRPRGWPEWAEPDVVDAFADRGISSPW
CCCHHHHHHHHHCCCCCCHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHCCCCCCC
SHQAEAAELAYAGRHVVIGTGPASGKSLAYQLPVLNALATDSRARALYLSPTKALGHDQL
CCCHHHHHHHHCCCEEEEECCCCCCCCEEEECCHHHHHHCCCCCEEEEECCHHHCCHHHH
RAAHALAAAVPRLADVAPTAYDGDSPDEVRRFARERSRWLFSNPEMTHLSVLRNHARWAV
HHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHCCEEECCCCHHHHHHHHHHHHHHH
LLRNLRFVIVDECHYYRGVFGSNVAMVLRRLLRLCARYSAHPTVIFASATTASPGATAAD
HHHCCCEEEEECHHHHHCCCCCCHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCCHHHH
LIGQPVVEVTEDGSPRGARTVALWEPALRSDVIGEHGAPVRRSAGAEAARVMADLIVEGA
HHCCCCEEECCCCCCCCCEEEEEECHHHHHHHCCCCCCCCHHHCCHHHHHHHHHHHHHHH
QTLTFVRSRRAAELTALGARARLVDIAPELSDTVASYRAGYLAEDRSALHQALAEGQLRG
HHHHHHHHHHHHHHHHHCCCCEEEECCCHHHHHHHHHHCCCCHHHHHHHHHHHHHCHHCC
LATTNALELGVDIAGLDAVVLAGFPGTVASFWQQAGRSGRRGQGALVVLIARDDPLDTYL
CCCCCHHHHCCEEECCCEEEEECCCHHHHHHHHHHCCCCCCCCCEEEEEEECCCCCCHHH
VHHPAALLDKPVERVVIDPVNPHLLGPQLLCAATELPLDDAEVRSWGAVEVAESLVDDGL
HHCCHHHHCCCCHHEEECCCCCCCCCCHHHHHHHCCCCCCHHHHCCCHHHHHHHHHHHHH
LRRRNGRYFPAPGVKPHAAVDVRGAIGGQIVIVEAGTGRLLGSVGVGQAPAAAHPGAVYL
HHHCCCCCCCCCCCCCCCEEEECCCCCCEEEEEECCCCCEEECCCCCCCCCCCCCCEEEE
HQGETYVVDSLDFQDGIAFVHAEDPGYATFAREVTDIAVTGTGERLVFGPVALGLVPVTV
ECCCEEEEECCCCCCCEEEEEECCCCHHHHHHHHHEEEEECCCCEEEECHHHHHHEEHHH
TNHVVGYLRRQLSGEVLDFVELDMPEHTLPTTAVMYTITSDALVRSGIEATRIPGSLHAA
HHHHHHHHHHHHCCHHHHHHHCCCCCCCCCCEEEEEEECHHHHHHCCCCHHCCCCCHHHH
EHAAIGLLPLVASCDRDDIGGMSTATGPEGLPSVFVYDGYPGGAGFAERGFRRARTWLGA
HHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCEEEEECCCCCCCCHHHHHHHHHHHHHCC
TAEAIEACECPSGCPSCVQSPKCGNGNDPLDKAGAVRVLRLVLAELSEESP
CHHHHHHHCCCCCCHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Hydrolase; Acting on acid anhydrides [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8760912; 9384377 [H]