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The map label for this gene is yeiE [C]

Identifier: 121638162

GI number: 121638162

Start: 2532032

End: 2532970

Strand: Reverse

Name: yeiE [C]

Synonym: BCG_2297c

Alternate gene names: 121638162

Gene position: 2532970-2532032 (Counterclockwise)

Preceding gene: 121638166

Following gene: 121638159

Centisome position: 57.9

GC content: 65.39

Gene sequence:

>939_bases
ATGCCGCTCAGCTCTCGTATGCCCGGACTCACCTGCTTCGAAATCTTTCTGGCCATCGCTGAGGCCGGCAGTCTTGGCGG
CGCCGCACGCGAACTCGGGTTGACTCAACAAGCTGTGTCAAGGCGGCTCGCATCGATGGAGGCCCAGATCGGGGTGCGAT
TGGCCATCCGGACGACACGTGGCTCCCAACTCACGCCTGCCGGCATCGTCGTCGCCGAATGGGCGGCCCGCTTGCTCGAA
GTCGCCGACGAGATCGATGCCGGCCTCGGCTCGCTGCGCACCGAAGGCCGCCAGCGCATCAGAGTGGTGGCCAGCCAGAC
GATAGCCGAACAGCTGATGCCGCATTGGATGCTGTCCTTGCGGGCCGCCGACATGCGCCGCGGTGGTACTGTCCCTGAGG
TAATCCTGACCGCCACCAATAGCGAGCATGCGATCGCAGCCGTTCGTGACGGCATCGCAGATCTTGGATTCATCGAAAAC
CCCTGTCCTCCCACGGGATTAGGCAGCGTTGTGGTTGCACGCGACGAACTGGTCGTCGTCGTGCCGCCGGGTCACAAGTG
GGCCCGACGGTCACGAGTAGTGAGCGCCCGGGAGCTCGCTCAGACGCCTTTGGTGACTCGCGAACCGAACTCTGGCATCC
GCGATTCACTCACCGCGGCGTTACGTGACACGCTCGGGGAGGACATGCAGCAAGCGCCACCGGTGCTGGAATTATCATCG
GCTGCGGCCGTGCGGGCCGCGGTCTTGGCCGGCGCTGGACCGGCTGCGATGAGCCGGCTAGCGATAGCCGATGACCTGGC
GTTCGGTCGATTACTCGCGGTCGACATCCCCGCGTTGAACCTGCGGCGCCAGCTTCGAGCCATCTGGGTCGGTGGGCGCA
CCCCGCCGGCGGGTGCGATACGAGACCTGCTCAGCCACATCACTTCCCGCAGCACGTAG

Upstream 100 bases:

>100_bases
GCAGTCGACGCTCGCGTGGGGGCATTTTTCGAGCATGGGCCGTCGTCACTAGGGGTCTGAATGTTGTTGGGAACAAACAT
TGGTTGTGATTTGATCAGGC

Downstream 100 bases:

>100_bases
GACCTCCGTCCGGCGAGCAGTCGCATAAGCCCCCGCACGCACGGCGTGTCGGGGGCTTTAGCGACTGCTCGCGGAGGTTG
CGCTGGGGTTGATGGACCCG

Product: LysR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 312; Mature: 311

Protein sequence:

>312_residues
MPLSSRMPGLTCFEIFLAIAEAGSLGGAARELGLTQQAVSRRLASMEAQIGVRLAIRTTRGSQLTPAGIVVAEWAARLLE
VADEIDAGLGSLRTEGRQRIRVVASQTIAEQLMPHWMLSLRAADMRRGGTVPEVILTATNSEHAIAAVRDGIADLGFIEN
PCPPTGLGSVVVARDELVVVVPPGHKWARRSRVVSARELAQTPLVTREPNSGIRDSLTAALRDTLGEDMQQAPPVLELSS
AAAVRAAVLAGAGPAAMSRLAIADDLAFGRLLAVDIPALNLRRQLRAIWVGGRTPPAGAIRDLLSHITSRST

Sequences:

>Translated_312_residues
MPLSSRMPGLTCFEIFLAIAEAGSLGGAARELGLTQQAVSRRLASMEAQIGVRLAIRTTRGSQLTPAGIVVAEWAARLLE
VADEIDAGLGSLRTEGRQRIRVVASQTIAEQLMPHWMLSLRAADMRRGGTVPEVILTATNSEHAIAAVRDGIADLGFIEN
PCPPTGLGSVVVARDELVVVVPPGHKWARRSRVVSARELAQTPLVTREPNSGIRDSLTAALRDTLGEDMQQAPPVLELSS
AAAVRAAVLAGAGPAAMSRLAIADDLAFGRLLAVDIPALNLRRQLRAIWVGGRTPPAGAIRDLLSHITSRST
>Mature_311_residues
PLSSRMPGLTCFEIFLAIAEAGSLGGAARELGLTQQAVSRRLASMEAQIGVRLAIRTTRGSQLTPAGIVVAEWAARLLEV
ADEIDAGLGSLRTEGRQRIRVVASQTIAEQLMPHWMLSLRAADMRRGGTVPEVILTATNSEHAIAAVRDGIADLGFIENP
CPPTGLGSVVVARDELVVVVPPGHKWARRSRVVSARELAQTPLVTREPNSGIRDSLTAALRDTLGEDMQQAPPVLELSSA
AAVRAAVLAGAGPAAMSRLAIADDLAFGRLLAVDIPALNLRRQLRAIWVGGRTPPAGAIRDLLSHITSRST

Specific function: Unknown

COG id: COG0583

COG function: function code K; Transcriptional regulator

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain

Homologues:

Organism=Escherichia coli, GI1788481, Length=279, Percent_Identity=33.3333333333333, Blast_Score=103, Evalue=2e-23,
Organism=Escherichia coli, GI1787879, Length=267, Percent_Identity=28.0898876404494, Blast_Score=72, Evalue=4e-14,
Organism=Escherichia coli, GI1788748, Length=253, Percent_Identity=28.0632411067194, Blast_Score=67, Evalue=2e-12,
Organism=Escherichia coli, GI1787806, Length=261, Percent_Identity=26.4367816091954, Blast_Score=65, Evalue=5e-12,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): Y2282_MYCTU (P67667)

Other databases:

- EMBL:   BX842579
- EMBL:   AE000516
- PIR:   F70731
- RefSeq:   NP_216798.1
- RefSeq:   NP_336810.1
- ProteinModelPortal:   P67667
- EnsemblBacteria:   EBMYCT00000001455
- EnsemblBacteria:   EBMYCT00000069766
- GeneID:   887253
- GeneID:   924083
- GenomeReviews:   AE000516_GR
- GenomeReviews:   AL123456_GR
- KEGG:   mtc:MT2340
- KEGG:   mtu:Rv2282c
- TIGR:   MT2340
- TubercuList:   Rv2282c
- GeneTree:   EBGT00050000015801
- HOGENOM:   HBG685425
- OMA:   SPRMPEL
- ProtClustDB:   CLSK791749
- GO:   GO:0005829
- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991
- Gene3D:   G3DSA:1.10.10.10

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate

EC number: NA

Molecular weight: Translated: 32990; Mature: 32858

Theoretical pI: Translated: 10.73; Mature: 10.73

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPLSSRMPGLTCFEIFLAIAEAGSLGGAARELGLTQQAVSRRLASMEAQIGVRLAIRTTR
CCCCCCCCCHHHHHHHHHHHHCCCCCCHHHHHCCHHHHHHHHHHHHHHHCCEEEEEEECC
GSQLTPAGIVVAEWAARLLEVADEIDAGLGSLRTEGRQRIRVVASQTIAEQLMPHWMLSL
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RAADMRRGGTVPEVILTATNSEHAIAAVRDGIADLGFIENPCPPTGLGSVVVARDELVVV
HHHHHHCCCCCCEEEEEECCCCHHHHHHHHCHHHCCCCCCCCCCCCCCCEEEECCCEEEE
VPPGHKWARRSRVVSARELAQTPLVTREPNSGIRDSLTAALRDTLGEDMQQAPPVLELSS
ECCCCHHHHHHHHHHHHHHHHCCCCEECCCCCHHHHHHHHHHHHHHHHHHHCCCCEEHHH
AAAVRAAVLAGAGPAAMSRLAIADDLAFGRLLAVDIPALNLRRQLRAIWVGGRTPPAGAI
HHHHHHHHHHCCCHHHHHHHHHHHHHHHHHEEEECCCHHHHHHHHHHEEECCCCCCHHHH
RDLLSHITSRST
HHHHHHHHCCCC
>Mature Secondary Structure 
PLSSRMPGLTCFEIFLAIAEAGSLGGAARELGLTQQAVSRRLASMEAQIGVRLAIRTTR
CCCCCCCCHHHHHHHHHHHHCCCCCCHHHHHCCHHHHHHHHHHHHHHHCCEEEEEEECC
GSQLTPAGIVVAEWAARLLEVADEIDAGLGSLRTEGRQRIRVVASQTIAEQLMPHWMLSL
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RAADMRRGGTVPEVILTATNSEHAIAAVRDGIADLGFIENPCPPTGLGSVVVARDELVVV
HHHHHHCCCCCCEEEEEECCCCHHHHHHHHCHHHCCCCCCCCCCCCCCCEEEECCCEEEE
VPPGHKWARRSRVVSARELAQTPLVTREPNSGIRDSLTAALRDTLGEDMQQAPPVLELSS
ECCCCHHHHHHHHHHHHHHHHCCCCEECCCCCHHHHHHHHHHHHHHHHHHHCCCCEEHHH
AAAVRAAVLAGAGPAAMSRLAIADDLAFGRLLAVDIPALNLRRQLRAIWVGGRTPPAGAI
HHHHHHHHHHCCCHHHHHHHHHHHHHHHHHEEEECCCHHHHHHHHHHEEECCCCCCHHHH
RDLLSHITSRST
HHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036