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The map label for this gene is idsA2 [H]

Identifier: 121638053

GI number: 121638053

Start: 2413377

End: 2414435

Strand: Direct

Name: idsA2 [H]

Synonym: BCG_2188

Alternate gene names: 121638053

Gene position: 2413377-2414435 (Clockwise)

Preceding gene: 121638051

Following gene: 121638054

Centisome position: 55.17

GC content: 67.61

Gene sequence:

>1059_bases
TTGGCCGGCGCCATCACCGACCAGCTGCGGAGGTATTTGCACGGCCGCCGCCGTGCGGCCGCCCACATGGGCAGTGACTA
CGACGGCCTGATCGCCGACCTGGAGGATTTCGTTCTCGGCGGGGGCAAGCGCCTACGACCGCTCTTCGCCTATTGGGGCT
GGCACGCCGTTGCCAGTCGGGAACCCGATCCTGATGTGCTGCTGCTGTTTTCCGCGCTGGAACTGCTGCACGCCTGGGCG
CTGGTCCACGACGACCTGATCGACCGTTCCGCCACCCGCCGGGGCCGCCCGACCGCCCAGCTGCGCTACGCGGCGCTGCA
CCGCGATCGGGACTGGCGGGGGTCACCGGACCAGTTCGGCATGTCGGCGGCCATCCTGCTCGGCGACCTCGCACAGGTCT
GGGCTGACGACATCGTCTCGAAGGTCTGCCAGTCCGCCCTGGCACCCGATGCCCAGCGGCGAGTGCATCGGGTGTGGGCC
GATATCCGCAACGAGGTGCTGGGCGGGCAATACCTCGACATCGTCGCAGAGGCCAGTGCCGCCGAGTCGATCGAGTCGGC
GATGAACGTCGCGACGCTCAAGACCGCCTGCTACACGGTATCGCGACCGCTACAGCTTGGGACGGCCGCCGCGGCCGACA
GATCCGACGTAGCGGCCATCTTCGAGCATTTCGGAGCGGACCTCGGCGTAGCGTTTCAGTTGCGCGACGACGTGCTTGGC
GTGTTTGGCGACCCAGCCGTGACGGGCAAGCCGTCCGGTGACGACCTAAAGTCGGGCAAGCGTACCGTGCTGGTAGCCGA
AGCGGTGGAATTGGCGGACAGGTCAGACCCCTTGGCGGCCAAACTATTACGGACCTCGATTGGCACCCGATTGACTGATG
CGCAGGTACGTGAACTGCGCACGGTCATCGAGGCAGTGGGCGCGCGCGCCGCCGCGGAGAGCCGCATCGCCGCGCTCACC
CAGCGAGCACTGGCCACCCTGGCGTCCGCACCCATCAACGCAACAGCCAAGGCCGGGCTGTCCGAACTGGCCATGATGGC
TGCGAACCGGTCCGCCTAA

Upstream 100 bases:

>100_bases
CGCGCCGGCGCGGAATACACTGTCGGGCCATAGGCACGCCAAATGAGAAAGGGGCGCCGCGCTGAGCCTGAATGCACCGG
CAGCACCGGCAGCGGTCCAG

Downstream 100 bases:

>100_bases
CCGATGACTACTCCGAGCCATGCTCCAGCGGTTGATTTGGCTACAGCGAAAGATGCTGTTGTCCAACACCTTTCGCGACT
TTTCGAGTTCACTACCGGTC

Product: putative geranylgeranyl pyrophosphate synthetase idsA2

Products: NA

Alternate protein names: (2E,6E)-farnesyl diphosphate synthase; Dimethylallyltranstransferase; Farnesyl diphosphate synthase; Farnesyl pyrophosphate synthase; FPP synthase; Geranyltranstransferase [H]

Number of amino acids: Translated: 352; Mature: 351

Protein sequence:

>352_residues
MAGAITDQLRRYLHGRRRAAAHMGSDYDGLIADLEDFVLGGGKRLRPLFAYWGWHAVASREPDPDVLLLFSALELLHAWA
LVHDDLIDRSATRRGRPTAQLRYAALHRDRDWRGSPDQFGMSAAILLGDLAQVWADDIVSKVCQSALAPDAQRRVHRVWA
DIRNEVLGGQYLDIVAEASAAESIESAMNVATLKTACYTVSRPLQLGTAAAADRSDVAAIFEHFGADLGVAFQLRDDVLG
VFGDPAVTGKPSGDDLKSGKRTVLVAEAVELADRSDPLAAKLLRTSIGTRLTDAQVRELRTVIEAVGARAAAESRIAALT
QRALATLASAPINATAKAGLSELAMMAANRSA

Sequences:

>Translated_352_residues
MAGAITDQLRRYLHGRRRAAAHMGSDYDGLIADLEDFVLGGGKRLRPLFAYWGWHAVASREPDPDVLLLFSALELLHAWA
LVHDDLIDRSATRRGRPTAQLRYAALHRDRDWRGSPDQFGMSAAILLGDLAQVWADDIVSKVCQSALAPDAQRRVHRVWA
DIRNEVLGGQYLDIVAEASAAESIESAMNVATLKTACYTVSRPLQLGTAAAADRSDVAAIFEHFGADLGVAFQLRDDVLG
VFGDPAVTGKPSGDDLKSGKRTVLVAEAVELADRSDPLAAKLLRTSIGTRLTDAQVRELRTVIEAVGARAAAESRIAALT
QRALATLASAPINATAKAGLSELAMMAANRSA
>Mature_351_residues
AGAITDQLRRYLHGRRRAAAHMGSDYDGLIADLEDFVLGGGKRLRPLFAYWGWHAVASREPDPDVLLLFSALELLHAWAL
VHDDLIDRSATRRGRPTAQLRYAALHRDRDWRGSPDQFGMSAAILLGDLAQVWADDIVSKVCQSALAPDAQRRVHRVWAD
IRNEVLGGQYLDIVAEASAAESIESAMNVATLKTACYTVSRPLQLGTAAAADRSDVAAIFEHFGADLGVAFQLRDDVLGV
FGDPAVTGKPSGDDLKSGKRTVLVAEAVELADRSDPLAAKLLRTSIGTRLTDAQVRELRTVIEAVGARAAAESRIAALTQ
RALATLASAPINATAKAGLSELAMMAANRSA

Specific function: Supplies Octaprenyl Diphosphate, The Precursor For The Side Chain Of The Isoprenoid Quinones Ubiquinone And Menaquinone. [C]

COG id: COG0142

COG function: function code H; Geranylgeranyl pyrophosphate synthase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the FPP/GGPP synthase family [H]

Homologues:

Organism=Escherichia coli, GI1789578, Length=302, Percent_Identity=28.8079470198675, Blast_Score=81, Evalue=8e-17,
Organism=Escherichia coli, GI1786623, Length=238, Percent_Identity=31.0924369747899, Blast_Score=71, Evalue=1e-13,
Organism=Drosophila melanogaster, GI24651612, Length=250, Percent_Identity=26, Blast_Score=70, Evalue=3e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000092
- InterPro:   IPR017446
- InterPro:   IPR008949 [H]

Pfam domain/function: PF00348 polyprenyl_synt [H]

EC number: =2.5.1.1; =2.5.1.10 [H]

Molecular weight: Translated: 37781; Mature: 37650

Theoretical pI: Translated: 6.73; Mature: 6.73

Prosite motif: PS00723 POLYPRENYL_SYNTHET_1 ; PS00444 POLYPRENYL_SYNTHET_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
AGAITDQLRRYLHGRRRAAAHMGSDYDGLIADLEDFVLGGGKRLRPLFAYWGWHAVASR
CCCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCC
EPDPDVLLLFSALELLHAWALVHDDLIDRSATRRGRPTAQLRYAALHRDRDWRGSPDQFG
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCCCCCHHHH
MSAAILLGDLAQVWADDIVSKVCQSALAPDAQRRVHRVWADIRNEVLGGQYLDIVAEASA
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHH
AESIESAMNVATLKTACYTVSRPLQLGTAAAADRSDVAAIFEHFGADLGVAFQLRDDVLG
HHHHHHHHHHHHHHHHHHHHCCCHHHCCHHHCCHHHHHHHHHHHCCCCEEEEEEHHHHHH
VFGDPAVTGKPSGDDLKSGKRTVLVAEAVELADRSDPLAAKLLRTSIGTRLTDAQVRELR
HCCCCCCCCCCCCCHHHCCCCEEEHHHHHHHHCCCCHHHHHHHHHHHCCCCCHHHHHHHH
TVIEAVGARAAAESRIAALTQRALATLASAPINATAKAGLSELAMMAANRSA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]