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The map label for this gene is 121637880

Identifier: 121637880

GI number: 121637880

Start: 2217659

End: 2218612

Strand: Direct

Name: 121637880

Synonym: BCG_2013

Alternate gene names: NA

Gene position: 2217659-2218612 (Clockwise)

Preceding gene: 121637879

Following gene: 121637881

Centisome position: 50.69

GC content: 65.09

Gene sequence:

>954_bases
ATGTCAGCCCAACAAACGAACCTCGGAATCGTGGTCGGTGTGGATGGTTCACCCTGCTCGCATACGGCAGTCGAATGGGC
CGCGCGCGATGCGCAGATGCGCAACGTTGCGCTCCGCGTGGTGCAGGTCGTGCCCCCGGTAATAACCGCCCCGGAAGGGT
GGGCATTTGAGTATTCGCGGTTTCAAGAAGCCCAAAAGCGCGAAATCGTCGAACACTCGTACCTGGTCGCCCAAGCGCAC
CAAATCGTCGAACAGGCCCACAAGGTCGCCCTCGAGGCATCCTCCTCAGGTCGCGCCGCGCAAATCACCGGCGAAGTGCT
GCACGGCCAGATAGTGCCCACGCTGGCCAACATCTCCAGGCAGGTCGCGATGGTCGTGCTGGGCTACCGAGGTCAGGGCG
CCGTAGCCGGCGCCTTGCTGGGATCGGTCAGCTCAAGCCTGGTTCGCCACGCTCATGGCCCTGTCGCCGTAATACCCGAG
GAGCCGCGACCGGCGCGCCCGCCGCACGCGCCGGTTGTGGTGGGCATCGACGGCTCGCCCACCTCGGGATTGGCGGCCGA
GATCGCCTTCGACGAGGCATCGCGCCGCGGCGTGGACTTGGTGGCGCTGCACGCGTGGAGCGACATGGGCCCCCTCGACT
TTCCTAGGCTCAATTGGGCGCCGATCGAATGGAGAAACCTCGAAGACGAGCAGGAGAAAATGCTCGCCCGGCGTCTGAGC
GGATGGCAAGACCGGTATCCCGATGTCGTCGTGCACAAAGTCGTGGTGTGCGATCGACCGGCACCCCGCCTGCTCGAATT
GGCACAAACCGCTCAGCTTGTGGTGGTTGGCAGCCACGGCCGCGGGGGGTTCCCCGGCATGCATCTCGGCTCAGTCAGCA
GAGCGGTGGTCAATTCCGGTCAGGCTCCGGTTATCGTCGCCCGAATCCCCCAAGATCCGGCAGTGCCGGCCTGA

Upstream 100 bases:

>100_bases
GCTAAAGACACTAATGCCCTTGGGTTAGGGACCATCGCCTCCTGACGCGATCGCGACAGCTGGCTAACGTCGGTAGTACA
CCCATGCAGAGGGGACGCCA

Downstream 100 bases:

>100_bases
GGGCCTGTGCGATCTGCTCGGGTGGTGCCCACCCGCGCGGAAAGCCCCGTCCGAACCGTGATTGGGCAACGTCGGGCCGG
GCCAGCAGCGCTGGACCGTA

Product: hypothetical protein

Products: NA

Alternate protein names: USP Rv1996

Number of amino acids: Translated: 317; Mature: 316

Protein sequence:

>317_residues
MSAQQTNLGIVVGVDGSPCSHTAVEWAARDAQMRNVALRVVQVVPPVITAPEGWAFEYSRFQEAQKREIVEHSYLVAQAH
QIVEQAHKVALEASSSGRAAQITGEVLHGQIVPTLANISRQVAMVVLGYRGQGAVAGALLGSVSSSLVRHAHGPVAVIPE
EPRPARPPHAPVVVGIDGSPTSGLAAEIAFDEASRRGVDLVALHAWSDMGPLDFPRLNWAPIEWRNLEDEQEKMLARRLS
GWQDRYPDVVVHKVVVCDRPAPRLLELAQTAQLVVVGSHGRGGFPGMHLGSVSRAVVNSGQAPVIVARIPQDPAVPA

Sequences:

>Translated_317_residues
MSAQQTNLGIVVGVDGSPCSHTAVEWAARDAQMRNVALRVVQVVPPVITAPEGWAFEYSRFQEAQKREIVEHSYLVAQAH
QIVEQAHKVALEASSSGRAAQITGEVLHGQIVPTLANISRQVAMVVLGYRGQGAVAGALLGSVSSSLVRHAHGPVAVIPE
EPRPARPPHAPVVVGIDGSPTSGLAAEIAFDEASRRGVDLVALHAWSDMGPLDFPRLNWAPIEWRNLEDEQEKMLARRLS
GWQDRYPDVVVHKVVVCDRPAPRLLELAQTAQLVVVGSHGRGGFPGMHLGSVSRAVVNSGQAPVIVARIPQDPAVPA
>Mature_316_residues
SAQQTNLGIVVGVDGSPCSHTAVEWAARDAQMRNVALRVVQVVPPVITAPEGWAFEYSRFQEAQKREIVEHSYLVAQAHQ
IVEQAHKVALEASSSGRAAQITGEVLHGQIVPTLANISRQVAMVVLGYRGQGAVAGALLGSVSSSLVRHAHGPVAVIPEE
PRPARPPHAPVVVGIDGSPTSGLAAEIAFDEASRRGVDLVALHAWSDMGPLDFPRLNWAPIEWRNLEDEQEKMLARRLSG
WQDRYPDVVVHKVVVCDRPAPRLLELAQTAQLVVVGSHGRGGFPGMHLGSVSRAVVNSGQAPVIVARIPQDPAVPA

Specific function: Unknown

COG id: COG0589

COG function: function code T; Universal stress protein UspA and related nucleotide-binding proteins

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the universal stress protein A family

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): Y1996_MYCTU (P0A5F7)

Other databases:

- EMBL:   BX842578
- EMBL:   AE000516
- PIR:   B70758
- RefSeq:   NP_216512.1
- RefSeq:   NP_336515.1
- ProteinModelPortal:   P0A5F7
- SMR:   P0A5F7
- EnsemblBacteria:   EBMYCT00000002491
- EnsemblBacteria:   EBMYCT00000073031
- GeneID:   888863
- GeneID:   923393
- GenomeReviews:   AE000516_GR
- GenomeReviews:   AL123456_GR
- KEGG:   mtc:MT2052
- KEGG:   mtu:Rv1996
- TIGR:   MT2052
- TubercuList:   Rv1996
- GeneTree:   EBGT00050000015432
- HOGENOM:   HBG733992
- OMA:   YARWRED
- ProtClustDB:   CLSK791548
- InterPro:   IPR014729
- InterPro:   IPR006015
- InterPro:   IPR006016
- Gene3D:   G3DSA:3.40.50.620
- PRINTS:   PR01438

Pfam domain/function: PF00582 Usp

EC number: NA

Molecular weight: Translated: 33880; Mature: 33749

Theoretical pI: Translated: 6.97; Mature: 6.97

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSAQQTNLGIVVGVDGSPCSHTAVEWAARDAQMRNVALRVVQVVPPVITAPEGWAFEYSR
CCCCCCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCEECCCCCCCHHHH
FQEAQKREIVEHSYLVAQAHQIVEQAHKVALEASSSGRAAQITGEVLHGQIVPTLANISR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCCCCEEEEEHHHHCCCHHHHHHHHHH
QVAMVVLGYRGQGAVAGALLGSVSSSLVRHAHGPVAVIPEEPRPARPPHAPVVVGIDGSP
EEEEEEEEECCCCHHHHHHHHHHHHHHHHHCCCCEEEECCCCCCCCCCCCCEEEEECCCC
TSGLAAEIAFDEASRRGVDLVALHAWSDMGPLDFPRLNWAPIEWRNLEDEQEKMLARRLS
CCCCEEEEEECHHCCCCCEEEEEEECCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHC
GWQDRYPDVVVHKVVVCDRPAPRLLELAQTAQLVVVGSHGRGGFPGMHLGSVSRAVVNSG
CHHHCCCCCEEEEEEEECCCCHHHHHHHCCCEEEEEECCCCCCCCCCCHHHHHHHHHCCC
QAPVIVARIPQDPAVPA
CCCEEEEECCCCCCCCC
>Mature Secondary Structure 
SAQQTNLGIVVGVDGSPCSHTAVEWAARDAQMRNVALRVVQVVPPVITAPEGWAFEYSR
CCCCCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCEECCCCCCCHHHH
FQEAQKREIVEHSYLVAQAHQIVEQAHKVALEASSSGRAAQITGEVLHGQIVPTLANISR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCCCCEEEEEHHHHCCCHHHHHHHHHH
QVAMVVLGYRGQGAVAGALLGSVSSSLVRHAHGPVAVIPEEPRPARPPHAPVVVGIDGSP
EEEEEEEEECCCCHHHHHHHHHHHHHHHHHCCCCEEEECCCCCCCCCCCCCEEEEECCCC
TSGLAAEIAFDEASRRGVDLVALHAWSDMGPLDFPRLNWAPIEWRNLEDEQEKMLARRLS
CCCCEEEEEECHHCCCCCEEEEEEECCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHC
GWQDRYPDVVVHKVVVCDRPAPRLLELAQTAQLVVVGSHGRGGFPGMHLGSVSRAVVNSG
CHHHCCCCCEEEEEEEECCCCHHHHHHHCCCEEEEEECCCCCCCCCCCHHHHHHHHHCCC
QAPVIVARIPQDPAVPA
CCCEEEEECCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036