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The map label for this gene is srpS [H]

Identifier: 121637627

GI number: 121637627

Start: 1950857

End: 1951636

Strand: Direct

Name: srpS [H]

Synonym: BCG_1758

Alternate gene names: 121637627

Gene position: 1950857-1951636 (Clockwise)

Preceding gene: 121637626

Following gene: 121637630

Centisome position: 44.6

GC content: 70.26

Gene sequence:

>780_bases
GTGTCCGCCGAAGAGCAGGACACCCGCAGTGGTGGCATCCAGGTGATCGCGCGGGCGGCCGAACTGCTGCGGGTGCTGCA
GGCGCACCCCGGCGGTCTCAGCCAGGCCGAGATCGGCGAGCGGGTGGGCATGGCCCGCTCGACCGTGAGCCGGATCCTCA
ACGCGCTGGAGGACGAGGGGCTGGTGGCCTCGCGCGGGGCCCGGGGACCCTATCGGCTGGGCCCGGAGATCACGCGGATG
GCCACCACGGTACGGCTGGGTGTCGTCACGGAGATGCACCCGTTCTTGACGGAGTTGTCGCGCGAGCTGGACGAGACGGT
GGACTTGTCGATCCTGGACGGGGATCGGGCGGACGTCGTGGACCAGGTCGTGCCGCCGCAGCGGCTGCGGGCCGTGAGCG
CGGTGGGGGAGTCGTTTCCGCTGTACTGCTGCGCCAACGGCAAGGCGCTGCTGGCCGCGTTGCCGCCTGAGCGGCAAGCC
CGCGCGCTGCCGAGTCGACTGGCGCCGCTGACGGCGAACACCATCACCGACCGCGCGGCGTTGCGGGACGAGCTCAATCG
CATCCGGGTGGACGGTGTCGCCTACGACCGTGAGGAGCAGACCGAAGGCATCTGCGCGGTGGGCGCGGTGCTACGGGGGG
TGTCGGTTGAGTTGGTGGCGGTGAGTGTGCCGGTGCCCGCGCAGCGGTTCTACGGCCGTGAAGCCGAGTTGGCCGGTGCT
CTGCTGGCCTGGGTTTCGAAGGTAGACGCGTGGTTCAACGGCACTGAGGATCGCAAATGA

Upstream 100 bases:

>100_bases
ACGATACGTCTCGCCGAAGCCTTGGACCTGCCGATCGCCTCGGTCGAAGAAGCCGAGGCGGCGCTGCAGCTGCCCGGCAC
GTCCTGAGAGGAGCTCGCTT

Downstream 100 bases:

>100_bases
CAGAAGCGTTGTGCGACAAGCTCGTTGGGGCCTGGGACCTGGTGTCCTACGTGGAGCGGGCCGCGGCTTTGGCGTTGGGA
TACCTGGCCTACGGCGGACG

Product: putative transcriptional regulatory protein

Products: NA

Alternate protein names: Solvent efflux pump srpABC operon corepressor [H]

Number of amino acids: Translated: 259; Mature: 258

Protein sequence:

>259_residues
MSAEEQDTRSGGIQVIARAAELLRVLQAHPGGLSQAEIGERVGMARSTVSRILNALEDEGLVASRGARGPYRLGPEITRM
ATTVRLGVVTEMHPFLTELSRELDETVDLSILDGDRADVVDQVVPPQRLRAVSAVGESFPLYCCANGKALLAALPPERQA
RALPSRLAPLTANTITDRAALRDELNRIRVDGVAYDREEQTEGICAVGAVLRGVSVELVAVSVPVPAQRFYGREAELAGA
LLAWVSKVDAWFNGTEDRK

Sequences:

>Translated_259_residues
MSAEEQDTRSGGIQVIARAAELLRVLQAHPGGLSQAEIGERVGMARSTVSRILNALEDEGLVASRGARGPYRLGPEITRM
ATTVRLGVVTEMHPFLTELSRELDETVDLSILDGDRADVVDQVVPPQRLRAVSAVGESFPLYCCANGKALLAALPPERQA
RALPSRLAPLTANTITDRAALRDELNRIRVDGVAYDREEQTEGICAVGAVLRGVSVELVAVSVPVPAQRFYGREAELAGA
LLAWVSKVDAWFNGTEDRK
>Mature_258_residues
SAEEQDTRSGGIQVIARAAELLRVLQAHPGGLSQAEIGERVGMARSTVSRILNALEDEGLVASRGARGPYRLGPEITRMA
TTVRLGVVTEMHPFLTELSRELDETVDLSILDGDRADVVDQVVPPQRLRAVSAVGESFPLYCCANGKALLAALPPERQAR
ALPSRLAPLTANTITDRAALRDELNRIRVDGVAYDREEQTEGICAVGAVLRGVSVELVAVSVPVPAQRFYGREAELAGAL
LAWVSKVDAWFNGTEDRK

Specific function: In conjunction with srpR represses the srpABC operon [H]

COG id: COG1414

COG function: function code K; Transcriptional regulator

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 iclR-ED (iclR effector binding) domain [H]

Homologues:

Organism=Escherichia coli, GI1789999, Length=209, Percent_Identity=32.0574162679426, Blast_Score=103, Evalue=1e-23,
Organism=Escherichia coli, GI87082359, Length=244, Percent_Identity=25, Blast_Score=89, Evalue=3e-19,
Organism=Escherichia coli, GI1786468, Length=230, Percent_Identity=28.695652173913, Blast_Score=80, Evalue=2e-16,
Organism=Escherichia coli, GI1788131, Length=199, Percent_Identity=30.6532663316583, Blast_Score=78, Evalue=7e-16,
Organism=Escherichia coli, GI1786715, Length=223, Percent_Identity=26.457399103139, Blast_Score=72, Evalue=3e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014757
- InterPro:   IPR005471
- InterPro:   IPR011991 [H]

Pfam domain/function: PF09339 HTH_IclR; PF01614 IclR [H]

EC number: NA

Molecular weight: Translated: 27905; Mature: 27774

Theoretical pI: Translated: 4.93; Mature: 4.93

Prosite motif: PS51077 HTH_ICLR ; PS51078 ICLR_ED

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSAEEQDTRSGGIQVIARAAELLRVLQAHPGGLSQAEIGERVGMARSTVSRILNALEDEG
CCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCC
LVASRGARGPYRLGPEITRMATTVRLGVVTEMHPFLTELSRELDETVDLSILDGDRADVV
CEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCEEEECCCHHHHH
DQVVPPQRLRAVSAVGESFPLYCCANGKALLAALPPERQARALPSRLAPLTANTITDRAA
HHCCCHHHHHHHHHHCCCCCEEEECCCCEEEEECCCHHHHHHHHHHHCCCHHHHHHHHHH
LRDELNRIRVDGVAYDREEQTEGICAVGAVLRGVSVELVAVSVPVPAQRFYGREAELAGA
HHHHHHHEEECCEEECCHHHHCHHHHHHHHHHCCCEEEEEEECCCCHHHHCCCHHHHHHH
LLAWVSKVDAWFNGTEDRK
HHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure 
SAEEQDTRSGGIQVIARAAELLRVLQAHPGGLSQAEIGERVGMARSTVSRILNALEDEG
CCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCC
LVASRGARGPYRLGPEITRMATTVRLGVVTEMHPFLTELSRELDETVDLSILDGDRADVV
CEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCEEEECCCHHHHH
DQVVPPQRLRAVSAVGESFPLYCCANGKALLAALPPERQARALPSRLAPLTANTITDRAA
HHCCCHHHHHHHHHHCCCCCEEEECCCCEEEEECCCHHHHHHHHHHHCCCHHHHHHHHHH
LRDELNRIRVDGVAYDREEQTEGICAVGAVLRGVSVELVAVSVPVPAQRFYGREAELAGA
HHHHHHHEEECCEEECCHHHHCHHHHHHHHHHCCCEEEEEEECCCCHHHHCCCHHHHHHH
LLAWVSKVDAWFNGTEDRK
HHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA