Click here to switch to the map view.

The map label for this gene is PPE20 [H]

Identifier: 121637317

GI number: 121637317

Start: 1586929

End: 1588548

Strand: Direct

Name: PPE20 [H]

Synonym: BCG_1448

Alternate gene names: 121637317

Gene position: 1586929-1588548 (Clockwise)

Preceding gene: 121637316

Following gene: 121637318

Centisome position: 36.28

GC content: 65.62

Gene sequence:

>1620_bases
ATGACCGAGCCGTGGATAGCCTTCCCTCCCGAGGTGCACTCGGCGATGCTGAACTACGGTGCGGGCGTTGGGCCGATGTT
GATCTCCGCCACGCAGAATGGGGAGCTCAGCGCCCAATACGCAGAAGCGGCATCCGAGGTCGAGGAATTGTTGGGGGTGG
TGGCCTCCGAGGGATGGCAGGGGCAAGCCGCCGAGGCGTTTGTCGCCGCGTACATGCCGTTTCTGGCGTGGCTGATCCAA
GCCAGCGCCGACTGCGTGGAAATGGCCGCCCAGCAACACGCCGTCATCGAGGCCTACACTGCCGCGGTAGAGCTGATGCC
TACTCAGGTCGAACTGGCCGCCAACCAAATCAAGCTCGCGGTGTTGGTAGCGACCAATTTCTTTGGCATCAACACCATTC
CCATTGCGATCAATGAGGCCGAGTACGTGGAGATGTGGGTTCGGGCCGCCACCACGATGGCGACCTATTCAACAGTCTCC
AGATCGGCGCTCTCCGCGATGCCGCACACCAGCCCCCCGCCGCTGATCCTGAAATCCGATGAACTGCTCCCCGACACCGG
GGAGGACTCCGATGAAGACGGCCACAACCATGGCGGTCACAGTCATGGCGGTCACGCCAGGATGATCGATAACTTCTTTG
CCGAAATCCTGCGTGGCGTCAGCGCGGGCCGCATTGTTTGGGACCCCGTCAACGGCACCCTCAACGGACTCGACTACGAC
GATTACGTCTACCCCGGTCACGCGATCTGGTGGCTGGCTCGAGGCCTCGAGTTTTTTCAGGATGGTGAACAATTTGGCGA
ACTGTTGTTCACCAATCCGACTGGGGCTTTTCAGTTCCTCCTCTACGTCGTTGTGGTGGATTTGCCGACGCACATAGCCC
AGATCGCTACCTGGCTGGGCCAGTACCCGCAGTTGCTGTCGGCTGCCCTCACTGGCGTCATCGCCCACCTGGGAGCAATA
ACTGGTTTGGCGGGCCTATCCGGCCTGAGCGCCATTCCGTCTGCTGCGATACCCGCCGTTGTACCGGAGCTGACACCCGT
CGCGGCCGCGCCGCCTATGTTGGCGGTCGCCGGGGTGGGCCCTGCAGTCGCCGCGCCGGGCATGCTCCCCGCCTCAGCAC
CCGCACCGGCGGCAGCGGCCGGCGCCACCGCAGCCGGCCCGACGCCGCCGGCGACTGGTTTCGGAGGCTTCCCGCCCTAC
CTGGTCGGCGGTGGCGGCCCAGGAATAGGGTTCGGCTCGGGACAGTCGGCCCACGCCAAGGCCGCGGCGTCCGATTCCGC
TGCAGCCGAGTCGGCGGCCCAGGCCTCGGCGCGTGCGCAGGCGCGTGCTGCACGGCGGGGCCGCTCGGCGGCGAAGGCAC
GTGGCCATCGTGACGAATTCGTCACGATGGACATGGGTTTCGACGCGGCAGCTCCGGCCCCAGAGCACCAGCCGGGTGCC
CGGGCGTCCGACTGTGGTGCGGGACCTATCGGATTTGCTGGCACGGTGCGCAAAGAGGCGGTCGTGAAAGCGGCGGGGTT
GACCACGCTGGCCGGTGACGACTTCGGCGGCGGCCCAACGATGCCGATGATGCCCGGCACCTGGACCCATGATCAGGGCG
TGTTCGACGAGCATCGCTGA

Upstream 100 bases:

>100_bases
TTGAGGAGCTCGGCCGCTCGGGGGTCGGGGTGGCCGAATCGGGTGCCAGTTATGCCGCTAGGGATGCGCTGGCGGCGGCG
TCGTATCTCAGCGGTGGGCT

Downstream 100 bases:

>100_bases
TAGCTGACTGGGCAGTGGCTGGCAAACAGCTGAGAGAGCACTCGAGAGCTATCGTCAGGGCAATGTCCGATGATGCTGAG
CACCCGCGTTTGGGGCACTA

Product: PPE family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 539; Mature: 538

Protein sequence:

>539_residues
MTEPWIAFPPEVHSAMLNYGAGVGPMLISATQNGELSAQYAEAASEVEELLGVVASEGWQGQAAEAFVAAYMPFLAWLIQ
ASADCVEMAAQQHAVIEAYTAAVELMPTQVELAANQIKLAVLVATNFFGINTIPIAINEAEYVEMWVRAATTMATYSTVS
RSALSAMPHTSPPPLILKSDELLPDTGEDSDEDGHNHGGHSHGGHARMIDNFFAEILRGVSAGRIVWDPVNGTLNGLDYD
DYVYPGHAIWWLARGLEFFQDGEQFGELLFTNPTGAFQFLLYVVVVDLPTHIAQIATWLGQYPQLLSAALTGVIAHLGAI
TGLAGLSGLSAIPSAAIPAVVPELTPVAAAPPMLAVAGVGPAVAAPGMLPASAPAPAAAAGATAAGPTPPATGFGGFPPY
LVGGGGPGIGFGSGQSAHAKAAASDSAAAESAAQASARAQARAARRGRSAAKARGHRDEFVTMDMGFDAAAPAPEHQPGA
RASDCGAGPIGFAGTVRKEAVVKAAGLTTLAGDDFGGGPTMPMMPGTWTHDQGVFDEHR

Sequences:

>Translated_539_residues
MTEPWIAFPPEVHSAMLNYGAGVGPMLISATQNGELSAQYAEAASEVEELLGVVASEGWQGQAAEAFVAAYMPFLAWLIQ
ASADCVEMAAQQHAVIEAYTAAVELMPTQVELAANQIKLAVLVATNFFGINTIPIAINEAEYVEMWVRAATTMATYSTVS
RSALSAMPHTSPPPLILKSDELLPDTGEDSDEDGHNHGGHSHGGHARMIDNFFAEILRGVSAGRIVWDPVNGTLNGLDYD
DYVYPGHAIWWLARGLEFFQDGEQFGELLFTNPTGAFQFLLYVVVVDLPTHIAQIATWLGQYPQLLSAALTGVIAHLGAI
TGLAGLSGLSAIPSAAIPAVVPELTPVAAAPPMLAVAGVGPAVAAPGMLPASAPAPAAAAGATAAGPTPPATGFGGFPPY
LVGGGGPGIGFGSGQSAHAKAAASDSAAAESAAQASARAQARAARRGRSAAKARGHRDEFVTMDMGFDAAAPAPEHQPGA
RASDCGAGPIGFAGTVRKEAVVKAAGLTTLAGDDFGGGPTMPMMPGTWTHDQGVFDEHR
>Mature_538_residues
TEPWIAFPPEVHSAMLNYGAGVGPMLISATQNGELSAQYAEAASEVEELLGVVASEGWQGQAAEAFVAAYMPFLAWLIQA
SADCVEMAAQQHAVIEAYTAAVELMPTQVELAANQIKLAVLVATNFFGINTIPIAINEAEYVEMWVRAATTMATYSTVSR
SALSAMPHTSPPPLILKSDELLPDTGEDSDEDGHNHGGHSHGGHARMIDNFFAEILRGVSAGRIVWDPVNGTLNGLDYDD
YVYPGHAIWWLARGLEFFQDGEQFGELLFTNPTGAFQFLLYVVVVDLPTHIAQIATWLGQYPQLLSAALTGVIAHLGAIT
GLAGLSGLSAIPSAAIPAVVPELTPVAAAPPMLAVAGVGPAVAAPGMLPASAPAPAAAAGATAAGPTPPATGFGGFPPYL
VGGGGPGIGFGSGQSAHAKAAASDSAAAESAAQASARAQARAARRGRSAAKARGHRDEFVTMDMGFDAAAPAPEHQPGAR
ASDCGAGPIGFAGTVRKEAVVKAAGLTTLAGDDFGGGPTMPMMPGTWTHDQGVFDEHR

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the mycobacterial PPE family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000030 [H]

Pfam domain/function: PF00823 PPE [H]

EC number: NA

Molecular weight: Translated: 55376; Mature: 55245

Theoretical pI: Translated: 4.48; Mature: 4.48

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTEPWIAFPPEVHSAMLNYGAGVGPMLISATQNGELSAQYAEAASEVEELLGVVASEGWQ
CCCCCCCCCHHHHHHHHHCCCCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHHCCCCC
GQAAEAFVAAYMPFLAWLIQASADCVEMAAQQHAVIEAYTAAVELMPTQVELAANQIKLA
CHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHEEEE
VLVATNFFGINTIPIAINEAEYVEMWVRAATTMATYSTVSRSALSAMPHTSPPPLILKSD
EEEEECCCCCEEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEECC
ELLPDTGEDSDEDGHNHGGHSHGGHARMIDNFFAEILRGVSAGRIVWDPVNGTLNGLDYD
CCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCEEEECCCCCCCCCCCC
DYVYPGHAIWWLARGLEFFQDGEQFGELLFTNPTGAFQFLLYVVVVDLPTHIAQIATWLG
CEECCCHHHHHHHHHHHHHHCHHHHCCEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHH
QYPQLLSAALTGVIAHLGAITGLAGLSGLSAIPSAAIPAVVPELTPVAAAPPMLAVAGVG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHCCCCCCCCCCCCEEEECCC
PAVAAPGMLPASAPAPAAAAGATAAGPTPPATGFGGFPPYLVGGGGPGIGFGSGQSAHAK
HHHHCCCCCCCCCCCCCHHCCCCCCCCCCCCCCCCCCCCEEECCCCCCCCCCCCCCCHHH
AAASDSAAAESAAQASARAQARAARRGRSAAKARGHRDEFVTMDMGFDAAAPAPEHQPGA
HHCCHHHHHHHHHHHHHHHHHHHHHHCHHHHHHCCCCCCEEEEECCCCCCCCCCCCCCCC
RASDCGAGPIGFAGTVRKEAVVKAAGLTTLAGDDFGGGPTMPMMPGTWTHDQGVFDEHR
CCCCCCCCCCCCCHHHHHHHHHHHHCCEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure 
TEPWIAFPPEVHSAMLNYGAGVGPMLISATQNGELSAQYAEAASEVEELLGVVASEGWQ
CCCCCCCCHHHHHHHHHCCCCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHHCCCCC
GQAAEAFVAAYMPFLAWLIQASADCVEMAAQQHAVIEAYTAAVELMPTQVELAANQIKLA
CHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHEEEE
VLVATNFFGINTIPIAINEAEYVEMWVRAATTMATYSTVSRSALSAMPHTSPPPLILKSD
EEEEECCCCCEEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEECC
ELLPDTGEDSDEDGHNHGGHSHGGHARMIDNFFAEILRGVSAGRIVWDPVNGTLNGLDYD
CCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCEEEECCCCCCCCCCCC
DYVYPGHAIWWLARGLEFFQDGEQFGELLFTNPTGAFQFLLYVVVVDLPTHIAQIATWLG
CEECCCHHHHHHHHHHHHHHCHHHHCCEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHH
QYPQLLSAALTGVIAHLGAITGLAGLSGLSAIPSAAIPAVVPELTPVAAAPPMLAVAGVG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHCCCCCCCCCCCCEEEECCC
PAVAAPGMLPASAPAPAAAAGATAAGPTPPATGFGGFPPYLVGGGGPGIGFGSGQSAHAK
HHHHCCCCCCCCCCCCCHHCCCCCCCCCCCCCCCCCCCCEEECCCCCCCCCCCCCCCHHH
AAASDSAAAESAAQASARAQARAARRGRSAAKARGHRDEFVTMDMGFDAAAPAPEHQPGA
HHCCHHHHHHHHHHHHHHHHHHHHHHCHHHHHHCCCCCCEEEEECCCCCCCCCCCCCCCC
RASDCGAGPIGFAGTVRKEAVVKAAGLTTLAGDDFGGGPTMPMMPGTWTHDQGVFDEHR
CCCCCCCCCCCCCHHHHHHHHHHHHCCEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036 [H]