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The map label for this gene is kdpE [H]

Identifier: 121636956

GI number: 121636956

Start: 1178912

End: 1179592

Strand: Reverse

Name: kdpE [H]

Synonym: BCG_1084c

Alternate gene names: 121636956

Gene position: 1179592-1178912 (Counterclockwise)

Preceding gene: 121636957

Following gene: 121636947

Centisome position: 26.97

GC content: 63.29

Gene sequence:

>681_bases
ATGACCCTCGTCTTGGTGATTGACGACGAACCCCAGATCCTGCGCGCGCTGCGTATCAACCTGACCGTGCGTGGCTACCA
GGTCATCACCGCCTCGACGGGTGCGGGTGCGCTGCGCGCCGCCGCTGAGCATCCGCCCGATGTGGTGATCCTCGACCTCG
GCCTGCCGGACATGTCGGGTATCGACGTGCTCGGCGGGCTGCGTGGCTGGTTGACGGCACCGGTGATCGTGTTGTCGGCG
CGTACCGATTCGTCGGACAAGGTCCAGGCCCTCGATGCGGGCGCCGACGATTACGTGACGAAACCGTTTGGAATGGACGA
GTTTCTGGCTCGGCTGCGCGCAGCGGTACGGCGTAACACCGCGGCCGCCGAGTTGGAGCAGCCGGTGATCGAAACCGATT
CATTCACCGTCGATCTGGCCGGCAAGAAGGTCATCAAAGACGGTGCCGAAGTGCATCTCACGCCGACCGAGTGGGGCATG
CTGGAAATGCTGGCCCGCAACCGCGGCAAGTTGGTCGGCCGCGGGGAGCTTCTCAAAGAAGTGTGGGGACCGGCATATGC
GACTGAAACCCATTACCTGCGGGTGTATCTGGCGCAGCTGCGGCGCAAATTGGAGGATGACCCGTCGCACCCCAAACATC
TGCTGACCGAATCAGGGATGGGCTACCGCTTCGAAGCCTAA

Upstream 100 bases:

>100_bases
GCGGCTTCGTCGAGGCTATGGGCGGCACGATTTCGGCTACCGATACCCCGGGCGGCGGGCTCACAGTGGTGATCGATCTA
GCGGCTCCCGAGGACCGCCC

Downstream 100 bases:

>100_bases
ATCACATCTGCCACAGGCGTTTCCGCTGGGAGCGGATGTACACTTTGCCCGCCTCGCAGCGACACGTTGGCGGATGCCCG
CAACGCCAACACGCGTTGGT

Product: putative transcriptional regulatory protein kdpE

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 226; Mature: 225

Protein sequence:

>226_residues
MTLVLVIDDEPQILRALRINLTVRGYQVITASTGAGALRAAAEHPPDVVILDLGLPDMSGIDVLGGLRGWLTAPVIVLSA
RTDSSDKVQALDAGADDYVTKPFGMDEFLARLRAAVRRNTAAAELEQPVIETDSFTVDLAGKKVIKDGAEVHLTPTEWGM
LEMLARNRGKLVGRGELLKEVWGPAYATETHYLRVYLAQLRRKLEDDPSHPKHLLTESGMGYRFEA

Sequences:

>Translated_226_residues
MTLVLVIDDEPQILRALRINLTVRGYQVITASTGAGALRAAAEHPPDVVILDLGLPDMSGIDVLGGLRGWLTAPVIVLSA
RTDSSDKVQALDAGADDYVTKPFGMDEFLARLRAAVRRNTAAAELEQPVIETDSFTVDLAGKKVIKDGAEVHLTPTEWGM
LEMLARNRGKLVGRGELLKEVWGPAYATETHYLRVYLAQLRRKLEDDPSHPKHLLTESGMGYRFEA
>Mature_225_residues
TLVLVIDDEPQILRALRINLTVRGYQVITASTGAGALRAAAEHPPDVVILDLGLPDMSGIDVLGGLRGWLTAPVIVLSAR
TDSSDKVQALDAGADDYVTKPFGMDEFLARLRAAVRRNTAAAELEQPVIETDSFTVDLAGKKVIKDGAEVHLTPTEWGML
EMLARNRGKLVGRGELLKEVWGPAYATETHYLRVYLAQLRRKLEDDPSHPKHLLTESGMGYRFEA

Specific function: Member of the two-component regulatory system kdpD/kdpE involved in the regulation of the kdp operon [H]

COG id: COG0745

COG function: function code TK; Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1786911, Length=224, Percent_Identity=49.5535714285714, Blast_Score=221, Evalue=3e-59,
Organism=Escherichia coli, GI1787375, Length=227, Percent_Identity=37.0044052863436, Blast_Score=143, Evalue=9e-36,
Organism=Escherichia coli, GI87082012, Length=223, Percent_Identity=34.0807174887892, Blast_Score=124, Evalue=5e-30,
Organism=Escherichia coli, GI1786784, Length=224, Percent_Identity=32.5892857142857, Blast_Score=120, Evalue=6e-29,
Organism=Escherichia coli, GI1786599, Length=224, Percent_Identity=33.9285714285714, Blast_Score=120, Evalue=6e-29,
Organism=Escherichia coli, GI1789809, Length=226, Percent_Identity=30.5309734513274, Blast_Score=118, Evalue=3e-28,
Organism=Escherichia coli, GI1788394, Length=223, Percent_Identity=29.1479820627803, Blast_Score=111, Evalue=4e-26,
Organism=Escherichia coli, GI2367329, Length=227, Percent_Identity=32.15859030837, Blast_Score=109, Evalue=2e-25,
Organism=Escherichia coli, GI1790552, Length=202, Percent_Identity=33.1683168316832, Blast_Score=109, Evalue=2e-25,
Organism=Escherichia coli, GI1790863, Length=227, Percent_Identity=29.5154185022026, Blast_Score=106, Evalue=1e-24,
Organism=Escherichia coli, GI1790860, Length=220, Percent_Identity=32.7272727272727, Blast_Score=104, Evalue=5e-24,
Organism=Escherichia coli, GI1789402, Length=223, Percent_Identity=31.8385650224215, Blast_Score=100, Evalue=1e-22,
Organism=Escherichia coli, GI1787229, Length=231, Percent_Identity=29.8701298701299, Blast_Score=98, Evalue=4e-22,
Organism=Escherichia coli, GI1788550, Length=123, Percent_Identity=34.9593495934959, Blast_Score=82, Evalue=4e-17,
Organism=Escherichia coli, GI145693140, Length=234, Percent_Identity=26.9230769230769, Blast_Score=74, Evalue=1e-14,
Organism=Escherichia coli, GI1790299, Length=142, Percent_Identity=32.3943661971831, Blast_Score=66, Evalue=2e-12,
Organism=Escherichia coli, GI1788712, Length=114, Percent_Identity=34.2105263157895, Blast_Score=64, Evalue=1e-11,
Organism=Escherichia coli, GI145693157, Length=105, Percent_Identity=34.2857142857143, Blast_Score=63, Evalue=1e-11,
Organism=Escherichia coli, GI1788521, Length=145, Percent_Identity=35.1724137931034, Blast_Score=62, Evalue=2e-11,
Organism=Escherichia coli, GI1790437, Length=133, Percent_Identity=31.5789473684211, Blast_Score=62, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001867
- InterPro:   IPR001789
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00072 Response_reg; PF00486 Trans_reg_C [H]

EC number: NA

Molecular weight: Translated: 24742; Mature: 24611

Theoretical pI: Translated: 5.37; Mature: 5.37

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTLVLVIDDEPQILRALRINLTVRGYQVITASTGAGALRAAAEHPPDVVILDLGLPDMSG
CEEEEEECCCHHHHHHHHEEEEEEEEEEEEECCCCCHHHHHCCCCCCEEEEECCCCCCCC
IDVLGGLRGWLTAPVIVLSARTDSSDKVQALDAGADDYVTKPFGMDEFLARLRAAVRRNT
CHHHHHHHHHHHCCEEEEEECCCCCCCEEEECCCCCCCCCCCCCHHHHHHHHHHHHHCCH
AAAELEQPVIETDSFTVDLAGKKVIKDGAEVHLTPTEWGMLEMLARNRGKLVGRGELLKE
HHHHHHCCCCCCCCEEEEECCCHHHCCCCEEEECCCCHHHHHHHHHCCCCEEEHHHHHHH
VWGPAYATETHYLRVYLAQLRRKLEDDPSHPKHLLTESGMGYRFEA
HCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCHHHHHCCCCCEEECC
>Mature Secondary Structure 
TLVLVIDDEPQILRALRINLTVRGYQVITASTGAGALRAAAEHPPDVVILDLGLPDMSG
EEEEEECCCHHHHHHHHEEEEEEEEEEEEECCCCCHHHHHCCCCCCEEEEECCCCCCCC
IDVLGGLRGWLTAPVIVLSARTDSSDKVQALDAGADDYVTKPFGMDEFLARLRAAVRRNT
CHHHHHHHHHHHCCEEEEEECCCCCCCEEEECCCCCCCCCCCCCHHHHHHHHHHHHHCCH
AAAELEQPVIETDSFTVDLAGKKVIKDGAEVHLTPTEWGMLEMLARNRGKLVGRGELLKE
HHHHHHCCCCCCCCEEEEECCCHHHCCCCEEEECCCCHHHHHHHHHCCCCEEEHHHHHHH
VWGPAYATETHYLRVYLAQLRRKLEDDPSHPKHLLTESGMGYRFEA
HCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCHHHHHCCCCCEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1532388; 8905232; 9278503 [H]