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The map label for this gene is moaC

Identifier: 121636787

GI number: 121636787

Start: 993416

End: 993844

Strand: Direct

Name: moaC

Synonym: BCG_0916

Alternate gene names: 121636787

Gene position: 993416-993844 (Clockwise)

Preceding gene: 121636786

Following gene: 121636788

Centisome position: 22.71

GC content: 64.1

Gene sequence:

>429_bases
ATGGTCGATATCACCGAGAAGGCAACCACGAAGCGAACAGCCGTTGCCGCGGGCATCTTACGTACCTCGGCGCAGGTGGT
GGCGCTGATCTCGACTGGCGGGCTGCCCAAAGGGGATGCGCTGGCCACCGCGCGGGTGGCGGGCATTATGGCGGCCAAGC
GCACCAGCGACCTGATCCCGCTGTGCCATCAACTCGCGCTTACCGGAGTCGACGTCGATTTCACCGTCGGCCAGTTGGAT
ATCGAGATCACAGCGACGGTACGCAGTACCGACCGAACGGGCGTCGAGATGGAAGCGCTGACCGCTGTCAGCGTGGCCGC
CCTCACGCTCTACGACATGATCAAGGCGGTCGATCCGGGCGCGCTTATCGATGACATCCGGGTGCTCCACAAAGAAGGCG
GTCGTCGCGGGACCTGGACGAGGCGATGA

Upstream 100 bases:

>100_bases
CCGTCATCAATCGGTAAGCCGCCAGGATGGCCAGGGCTTCTGGGGCATCCGACTACCGCTCGGGCGAGCTGTCGCACCAG
GATGAGCGGGGGCAGCGCAC

Downstream 100 bases:

>100_bases
GCACCCGGTCCGCTCGAATTGTCGTTGTGTCGAGCCGCGCGGCGGCCGGTGTGTATACCGATGATTGCGGGCCGATTATC
GCTGGATGGCTTGAACAGCA

Product: molybdenum cofactor biosynthesis protein MoaC

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 142; Mature: 142

Protein sequence:

>142_residues
MVDITEKATTKRTAVAAGILRTSAQVVALISTGGLPKGDALATARVAGIMAAKRTSDLIPLCHQLALTGVDVDFTVGQLD
IEITATVRSTDRTGVEMEALTAVSVAALTLYDMIKAVDPGALIDDIRVLHKEGGRRGTWTRR

Sequences:

>Translated_142_residues
MVDITEKATTKRTAVAAGILRTSAQVVALISTGGLPKGDALATARVAGIMAAKRTSDLIPLCHQLALTGVDVDFTVGQLD
IEITATVRSTDRTGVEMEALTAVSVAALTLYDMIKAVDPGALIDDIRVLHKEGGRRGTWTRR
>Mature_142_residues
MVDITEKATTKRTAVAAGILRTSAQVVALISTGGLPKGDALATARVAGIMAAKRTSDLIPLCHQLALTGVDVDFTVGQLD
IEITATVRSTDRTGVEMEALTAVSVAALTLYDMIKAVDPGALIDDIRVLHKEGGRRGTWTRR

Specific function: Together with moaA, is involved in the conversion of a guanosine derivative (5'-GTP) into molybdopterin precursor Z

COG id: COG0315

COG function: function code H; Molybdenum cofactor biosynthesis enzyme

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the moaC family

Homologues:

Organism=Escherichia coli, GI1787001, Length=141, Percent_Identity=49.645390070922, Blast_Score=123, Evalue=5e-30,
Organism=Caenorhabditis elegans, GI32566331, Length=136, Percent_Identity=41.9117647058824, Blast_Score=112, Evalue=5e-26,
Organism=Drosophila melanogaster, GI28574492, Length=138, Percent_Identity=48.5507246376812, Blast_Score=125, Evalue=7e-30,
Organism=Drosophila melanogaster, GI28574490, Length=138, Percent_Identity=48.5507246376812, Blast_Score=124, Evalue=2e-29,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): MOAC2_MYCBO (P0A5K7)

Other databases:

- EMBL:   BX248336
- RefSeq:   NP_854545.1
- ProteinModelPortal:   P0A5K7
- SMR:   P0A5K7
- EnsemblBacteria:   EBMYCT00000014756
- GeneID:   1092764
- GenomeReviews:   BX248333_GR
- KEGG:   mbo:Mb0888
- GeneTree:   EBGT00050000016668
- HOGENOM:   HBG605231
- ProtClustDB:   PRK09364
- BioCyc:   MBOV233413:MB0888-MONOMER
- HAMAP:   MF_01224_B
- InterPro:   IPR023045
- InterPro:   IPR023046
- InterPro:   IPR002820
- Gene3D:   G3DSA:3.30.70.640
- TIGRFAMs:   TIGR00581

Pfam domain/function: PF01967 MoaC; SSF55040 MoaC

EC number: NA

Molecular weight: Translated: 14957; Mature: 14957

Theoretical pI: Translated: 8.52; Mature: 8.52

Prosite motif: NA

Important sites: ACT_SITE 137-137

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVDITEKATTKRTAVAAGILRTSAQVVALISTGGLPKGDALATARVAGIMAAKRTSDLIP
CCCCCCCHHHHHHHHHHHHHHCCCEEEEEEECCCCCCCCHHHHHHHHHHHHHHCCCCHHH
LCHQLALTGVDVDFTVGQLDIEITATVRSTDRTGVEMEALTAVSVAALTLYDMIKAVDPG
HHHHHHHCCCCCEEEEEEEEEEEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCC
ALIDDIRVLHKEGGRRGTWTRR
HHHHHHHHHHHCCCCCCCCCCC
>Mature Secondary Structure
MVDITEKATTKRTAVAAGILRTSAQVVALISTGGLPKGDALATARVAGIMAAKRTSDLIP
CCCCCCCHHHHHHHHHHHHHHCCCEEEEEEECCCCCCCCHHHHHHHHHHHHHHCCCCHHH
LCHQLALTGVDVDFTVGQLDIEITATVRSTDRTGVEMEALTAVSVAALTLYDMIKAVDPG
HHHHHHHCCCCCEEEEEEEEEEEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCC
ALIDDIRVLHKEGGRRGTWTRR
HHHHHHHHHHHCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Involved in molybdopterin biosynthesis [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12788972