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The map label for this gene is fucA [H]

Identifier: 121636649

GI number: 121636649

Start: 851306

End: 851962

Strand: Reverse

Name: fucA [H]

Synonym: BCG_0777c

Alternate gene names: 121636649

Gene position: 851962-851306 (Counterclockwise)

Preceding gene: 121636650

Following gene: 121636648

Centisome position: 19.48

GC content: 67.58

Gene sequence:

>657_bases
ATGAACTTCGTTGACGACCCGGAATCCGCGGTGCTGGCGGCCGCCAAGGACATGTTGCGTCGGGGCCTGGTCGAGGGGAC
CGCCGGAAATATCTCAGCCAGGCGCTCGGACGGCAACGTGGTCATCACGCCGTCCTCGGTCGACTACGCCGAGATGCTGC
TCCACGATCTGGTGCTAGTCGACGCCGGCGGTGCGGTGCTGCACGCCAAGGACGGCCGGTCGCCGTCGACCGAACTAAAC
CTACACCTGGCGTGCTATCGCGCATTCGACGACATTGGCAGCGTGATCCACAGCCACCCGGTGTGGGCGACCATGTTCGC
CGTCGCCCATGAGCCGATTCCCGCCTGCATCGACGAGTTCGCGATCTACTGCGGCGGGGACGTTCGCTGCACCGAGTACG
CCGCGTCCGGTACACCCGAGGTCGGCCGCAACGCGGTGCGCGCGCTTGAGGGCCGCGCCGCCGCCCTGATCGCCAACCAC
GGCCTGGTGGCCGTGGGGCCCCGCCCCGACCAGGTGCTGCGCGTCACCGCCCTTGTTGAGCGCACCGCACAAATCGTTTG
GGGTGCCCGCGCTCTCGGTGGACCGGTGCCAATTCCTGAGGACGTGTGCCGTAACTTCACGGGCGTCTACGGCTATCTGC
GCGCGAATCCGCTCTAG

Upstream 100 bases:

>100_bases
ACACCGAGGCCCGGCAGGCGCGGATGGTCGCCGACGACCTGGGCGCACTGCTGTCCGGCAACAGGCCCGCCCATGTCGTC
AACCCGGAGGTATTGGGCTC

Downstream 100 bases:

>100_bases
CCGCACCGAGAGTGAATCGCACCACGCGACACGCCGAAAACCCATCGCGGTATTCACGCTCAACAGCCAGGACCCCCACG
TGCGCCCCCTATGGCGGCAC

Product: L-fuculose-phosphate aldolase

Products: NA

Alternate protein names: L-fuculose-1-phosphate aldolase [H]

Number of amino acids: Translated: 218; Mature: 218

Protein sequence:

>218_residues
MNFVDDPESAVLAAAKDMLRRGLVEGTAGNISARRSDGNVVITPSSVDYAEMLLHDLVLVDAGGAVLHAKDGRSPSTELN
LHLACYRAFDDIGSVIHSHPVWATMFAVAHEPIPACIDEFAIYCGGDVRCTEYAASGTPEVGRNAVRALEGRAAALIANH
GLVAVGPRPDQVLRVTALVERTAQIVWGARALGGPVPIPEDVCRNFTGVYGYLRANPL

Sequences:

>Translated_218_residues
MNFVDDPESAVLAAAKDMLRRGLVEGTAGNISARRSDGNVVITPSSVDYAEMLLHDLVLVDAGGAVLHAKDGRSPSTELN
LHLACYRAFDDIGSVIHSHPVWATMFAVAHEPIPACIDEFAIYCGGDVRCTEYAASGTPEVGRNAVRALEGRAAALIANH
GLVAVGPRPDQVLRVTALVERTAQIVWGARALGGPVPIPEDVCRNFTGVYGYLRANPL
>Mature_218_residues
MNFVDDPESAVLAAAKDMLRRGLVEGTAGNISARRSDGNVVITPSSVDYAEMLLHDLVLVDAGGAVLHAKDGRSPSTELN
LHLACYRAFDDIGSVIHSHPVWATMFAVAHEPIPACIDEFAIYCGGDVRCTEYAASGTPEVGRNAVRALEGRAAALIANH
GLVAVGPRPDQVLRVTALVERTAQIVWGARALGGPVPIPEDVCRNFTGVYGYLRANPL

Specific function: Fucose metabolism; third step. [C]

COG id: COG0235

COG function: function code G; Ribulose-5-phosphate 4-epimerase and related epimerases and aldolases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the aldolase class II family. AraD/FucA subfamily [H]

Homologues:

Organism=Escherichia coli, GI1789164, Length=185, Percent_Identity=34.0540540540541, Blast_Score=112, Evalue=3e-26,
Organism=Escherichia coli, GI1790642, Length=198, Percent_Identity=33.3333333333333, Blast_Score=85, Evalue=5e-18,
Organism=Escherichia coli, GI1786247, Length=210, Percent_Identity=30, Blast_Score=74, Evalue=7e-15,
Organism=Escherichia coli, GI1790008, Length=210, Percent_Identity=28.5714285714286, Blast_Score=68, Evalue=6e-13,
Organism=Escherichia coli, GI1789094, Length=177, Percent_Identity=26.5536723163842, Blast_Score=65, Evalue=4e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001303
- InterPro:   IPR004782 [H]

Pfam domain/function: PF00596 Aldolase_II [H]

EC number: =4.1.2.17 [H]

Molecular weight: Translated: 23111; Mature: 23111

Theoretical pI: Translated: 5.55; Mature: 5.55

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.3 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
2.3 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNFVDDPESAVLAAAKDMLRRGLVEGTAGNISARRSDGNVVITPSSVDYAEMLLHDLVLV
CCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCEEEECCCCEEEECCCCCHHHHHHHHHHEE
DAGGAVLHAKDGRSPSTELNLHLACYRAFDDIGSVIHSHPVWATMFAVAHEPIPACIDEF
ECCCEEEEECCCCCCCCEEEEEHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCHHHHHHHH
AIYCGGDVRCTEYAASGTPEVGRNAVRALEGRAAALIANHGLVAVGPRPDQVLRVTALVE
HHHCCCCEEEEEECCCCCCHHHHHHHHHHCCCCEEEEECCCEEEECCCCHHHHHHHHHHH
RTAQIVWGARALGGPVPIPEDVCRNFTGVYGYLRANPL
HHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHEEECCCC
>Mature Secondary Structure
MNFVDDPESAVLAAAKDMLRRGLVEGTAGNISARRSDGNVVITPSSVDYAEMLLHDLVLV
CCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCEEEECCCCEEEECCCCCHHHHHHHHHHEE
DAGGAVLHAKDGRSPSTELNLHLACYRAFDDIGSVIHSHPVWATMFAVAHEPIPACIDEF
ECCCEEEEECCCCCCCCEEEEEHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCHHHHHHHH
AIYCGGDVRCTEYAASGTPEVGRNAVRALEGRAAALIANHGLVAVGPRPDQVLRVTALVE
HHHCCCCEEEEEECCCCCCHHHHHHHHHHCCCCEEEEECCCEEEECCCCHHHHHHHHHHH
RTAQIVWGARALGGPVPIPEDVCRNFTGVYGYLRANPL
HHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]