| Definition | Mycobacterium bovis BCG str. Pasteur 1173P2, complete genome. |
|---|---|
| Accession | NC_008769 |
| Length | 4,374,522 |
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The map label for this gene is recBa [H]
Identifier: 121636549
GI number: 121636549
Start: 753205
End: 755898
Strand: Reverse
Name: recBa [H]
Synonym: BCG_0677c
Alternate gene names: 121636549
Gene position: 755898-753205 (Counterclockwise)
Preceding gene: 121636550
Following gene: 121636548
Centisome position: 17.28
GC content: 70.64
Gene sequence:
>2694_bases ATGGACCGCTTCGAGCTGCTGGGCCCGTTGCCGAGGGAGGGCACCACCACCGTGCTGGAAGCCAGCGCCGGCACCGGTAA GACGTTCGCGCTGGCCGGTCTGGTCACCCGCTATCTGGCCGAAACCGCCGCGACGCTCGACGAGATGTTGTTGATCACGT TCAACCGTGCGGCCAGCCGGGAGTTACGCGAGCGAGTGCGCGGGCAGATCGTCGAGGCCTTGGGCGCGCTACAAGGCGAC GCGCCGCCGAGCGGCGAGCTCGTCGAGCACCTGCTGCGCGGCAGCGACGCCGAGCGCGCCCAGAAGCGGTCGCGGCTGCG TGACGCGCTGGCCAACTTCGACGCGGCAACCATCGCCACCACCCACGAGTTCTGCGGCTCGGTGTTGAAATCCCTCGGTG TGGCCGGTGACAACGCCGCCGACGTGGAGCTCAAGGAGAGCCTTACCGACCTGGTCACTGAGATCGTGGACGATCGCTAT CTGGCGAACTTCGGTCGTCAGGAGACCGATCCGGAGCTGACCTACGCCGAGGCGCTGGCCCTGGCCCTTGCCGTCGTCGA CGACCCGTGCGCCCAACTGCGCCCGCCTGATCCCGAGCCCGGCAGCAAGGCAGCGGTGCGGCTGCGCTTTGCCGCCGAGG TGCTCGAGGAACTCGAGCGCCGCAAGGGCCGGCTGCGTGCGCAAGGATTCAACGATCTGCTGATCCGTTTGGCGACAGCC CTCGAGGCGGCCGACTCGCCAGCTCGCGATCGGATGCGGGAACGCTGGCGGATCGTGCTGGTGGACGAGTTTCAAGATAC CGACCCCATGCAGTGGCGGGTGCTCGAGCGCGCGTTTAGCCGGCATTCGGCGCTGATCCTGATCGGCGATCCCAAGCAGG CGATCTACGGCTTTCGCGGCGGCGACATCCACACCTACCTCAAGGCGGCCGGCACCGCCGATGCCCGCTACACGTTGGGC GTCAACTGGCGCAGCGACCGGGCGCTGGTCGAGAGCCTGCAGACGGTGCTGCGCGATGCGACCCTGGGTCACGCCGACAT CGTCGTCCGCGGCACCGACGCCCACCACGCCGGGCACCGCCTGGCCTCGGCGCCGCGCCCGGCGCCGTTTCGGTTGCGCG TGGTCAAACGGCACACGCTCGGGTATGACGGGACCGCCCACGTCCCGATCGAGGCGCTGCGCCGGCACATCCCCGACGAC CTGGCCGCCGACGTCGCGGCGCTACTGGCCAGCGGGGCCACCTTCGCCGGGCGGCCCGTGGTGGCCGCAGACATCGCGGT GATCGTCGAGCATCACAAAGACGCGCGGGCGTGCCGGAATGCGTTGGCGGAGGCGGGCATCCCGGCGATCTACACCGGTG ACACCGACGTGTTCGCCTCGCAGGCCGCCAAGGACTGGCTGTGCCTGCTGGAGGCGTTCGACGCGCCGCAGCGCAGCGGG CTGGTCCGCGCCGCCGCGTGCACGATGTTCTTCGGTGAGACCGCGGAATCGCTTGCCGCCGAGGGCGATGCGCTGACCGA TCGGGTGGCCGGCACGTTGCACGAGTGGGCCGACCACGCACGCCATCGCGGTGTGGCCGCGGTGTTTCAGGCCGCTCAGC TGGCCGGGATGGGCCGGCGCGTGCTGAGCCAGCGCGGCGGCGAACGGGACCTGACAGACCTGGCGCACATTGCGCAGCTG CTGCACGAGGCCGCTCATCGCGAGCGGCTCGGCCTGCCCGGGCTGCGCGATTGGCTGCGCCGCCAGGCCAAGGCGGGTGC CGGCCCGCCGGAACACAATCGCCGGTTGGACAGCGACGCCGCGGCGGTGCAGATCATGACCGTCTTCGTGGCCAAGGGAC TGCAGTTTCCCATCGTGTATCTGCCGTTCGCCTTCAACCGCAACGTCCGCAGCGACGACATCCTGCTGTATCACGACGAC GGCACCCGCTGCCTGTACATCGGCGGCAAGGACGGCGGTGCTCAGCGGCGCACCGTTGAGGGGCTGAACCGCGTCGAGGC GGCCCACGACAACCTCCGGCTCACCTATGTCGCGCTTACCCGCGCGCAATCGCAGGTCGTCGCGTGGTGGGCACCGACGT TCGACGAGGTCAACGGCGGGTTGTCGCGGTTGCTGCGCGGGCGCCGGCCCGGCCAGTCGCAGGTACCGGACCGGTGTACA CCACGCGTCACCGACGAGCAGGCCTGGGCGGTGTTCGCGCAGTGGGAGGCCGCGGGCGGGCCGTCGGTCGAGGAATCGGT CATCGGTGCTCGCAGTTCCCTCGAAAAGCCGGTGCCCGTACCCGGTTTCGAGGTTCGGCACTTTCACCGCCGGATCGACA CCACGTGGCGGCGGACCTCGTACTCGGATCTGGTGCGGGGCTCGGAAGCCGTCACCGTCACCAGCGAGCCGGCGGCCGGC GGCCGTGCGGACGAGGTGGAGATCGCCGTCTTCGCCGCGCCCGGTTCCGGCGCCGATCTGACATCACCGCTGGCCGCGCT GCCGTCGGGGGCGTCGTTCGGCTCGCTGGTGCACGCGGTGCTCGAGACCGCGGACCCAGCCGCTCCCGATCTGGCTGCCG AACTGGAAGCCCAGGTGCCCGGCACGCGCCGTGGTGGACCGTGGACGTCGACCACGCGCAGCTGGCTCCCGAACTGGCCC GAGCGTTGCTGCCGATGCACGACACGCCGCTGGGACCCGCCGCCGCCGCACTGA
Upstream 100 bases:
>100_bases AGCCCCGCGCGGGCGAAGAGGTCGCCGGGGAAGAGACCCGGCTAGGGGCGCTGGCCGCCCGGCTATGGCTGCCGCTGTTG GCCGCCGAAGGGTCGGTCTG
Downstream 100 bases:
>100_bases CATTGCGGCAGATCGGTGTGCGTGATCGTCTGCGGGAGTTGGACTTCGAGATGCCGCTGGCCGGGGGCGATCTGCGCGGC CGGTCCCCGGACGTGTCGCT
Product: putative exonuclease V subunit beta recBa
Products: NA
Alternate protein names: NA
Number of amino acids: Translated: 897; Mature: 897
Protein sequence:
>897_residues MDRFELLGPLPREGTTTVLEASAGTGKTFALAGLVTRYLAETAATLDEMLLITFNRAASRELRERVRGQIVEALGALQGD APPSGELVEHLLRGSDAERAQKRSRLRDALANFDAATIATTHEFCGSVLKSLGVAGDNAADVELKESLTDLVTEIVDDRY LANFGRQETDPELTYAEALALALAVVDDPCAQLRPPDPEPGSKAAVRLRFAAEVLEELERRKGRLRAQGFNDLLIRLATA LEAADSPARDRMRERWRIVLVDEFQDTDPMQWRVLERAFSRHSALILIGDPKQAIYGFRGGDIHTYLKAAGTADARYTLG VNWRSDRALVESLQTVLRDATLGHADIVVRGTDAHHAGHRLASAPRPAPFRLRVVKRHTLGYDGTAHVPIEALRRHIPDD LAADVAALLASGATFAGRPVVAADIAVIVEHHKDARACRNALAEAGIPAIYTGDTDVFASQAAKDWLCLLEAFDAPQRSG LVRAAACTMFFGETAESLAAEGDALTDRVAGTLHEWADHARHRGVAAVFQAAQLAGMGRRVLSQRGGERDLTDLAHIAQL LHEAAHRERLGLPGLRDWLRRQAKAGAGPPEHNRRLDSDAAAVQIMTVFVAKGLQFPIVYLPFAFNRNVRSDDILLYHDD GTRCLYIGGKDGGAQRRTVEGLNRVEAAHDNLRLTYVALTRAQSQVVAWWAPTFDEVNGGLSRLLRGRRPGQSQVPDRCT PRVTDEQAWAVFAQWEAAGGPSVEESVIGARSSLEKPVPVPGFEVRHFHRRIDTTWRRTSYSDLVRGSEAVTVTSEPAAG GRADEVEIAVFAAPGSGADLTSPLAALPSGASFGSLVHAVLETADPAAPDLAAELEAQVPGTRRGGPWTSTTRSWLPNWP ERCCRCTTRRWDPPPPH
Sequences:
>Translated_897_residues MDRFELLGPLPREGTTTVLEASAGTGKTFALAGLVTRYLAETAATLDEMLLITFNRAASRELRERVRGQIVEALGALQGD APPSGELVEHLLRGSDAERAQKRSRLRDALANFDAATIATTHEFCGSVLKSLGVAGDNAADVELKESLTDLVTEIVDDRY LANFGRQETDPELTYAEALALALAVVDDPCAQLRPPDPEPGSKAAVRLRFAAEVLEELERRKGRLRAQGFNDLLIRLATA LEAADSPARDRMRERWRIVLVDEFQDTDPMQWRVLERAFSRHSALILIGDPKQAIYGFRGGDIHTYLKAAGTADARYTLG VNWRSDRALVESLQTVLRDATLGHADIVVRGTDAHHAGHRLASAPRPAPFRLRVVKRHTLGYDGTAHVPIEALRRHIPDD LAADVAALLASGATFAGRPVVAADIAVIVEHHKDARACRNALAEAGIPAIYTGDTDVFASQAAKDWLCLLEAFDAPQRSG LVRAAACTMFFGETAESLAAEGDALTDRVAGTLHEWADHARHRGVAAVFQAAQLAGMGRRVLSQRGGERDLTDLAHIAQL LHEAAHRERLGLPGLRDWLRRQAKAGAGPPEHNRRLDSDAAAVQIMTVFVAKGLQFPIVYLPFAFNRNVRSDDILLYHDD GTRCLYIGGKDGGAQRRTVEGLNRVEAAHDNLRLTYVALTRAQSQVVAWWAPTFDEVNGGLSRLLRGRRPGQSQVPDRCT PRVTDEQAWAVFAQWEAAGGPSVEESVIGARSSLEKPVPVPGFEVRHFHRRIDTTWRRTSYSDLVRGSEAVTVTSEPAAG GRADEVEIAVFAAPGSGADLTSPLAALPSGASFGSLVHAVLETADPAAPDLAAELEAQVPGTRRGGPWTSTTRSWLPNWP ERCCRCTTRRWDPPPPH >Mature_897_residues MDRFELLGPLPREGTTTVLEASAGTGKTFALAGLVTRYLAETAATLDEMLLITFNRAASRELRERVRGQIVEALGALQGD APPSGELVEHLLRGSDAERAQKRSRLRDALANFDAATIATTHEFCGSVLKSLGVAGDNAADVELKESLTDLVTEIVDDRY LANFGRQETDPELTYAEALALALAVVDDPCAQLRPPDPEPGSKAAVRLRFAAEVLEELERRKGRLRAQGFNDLLIRLATA LEAADSPARDRMRERWRIVLVDEFQDTDPMQWRVLERAFSRHSALILIGDPKQAIYGFRGGDIHTYLKAAGTADARYTLG VNWRSDRALVESLQTVLRDATLGHADIVVRGTDAHHAGHRLASAPRPAPFRLRVVKRHTLGYDGTAHVPIEALRRHIPDD LAADVAALLASGATFAGRPVVAADIAVIVEHHKDARACRNALAEAGIPAIYTGDTDVFASQAAKDWLCLLEAFDAPQRSG LVRAAACTMFFGETAESLAAEGDALTDRVAGTLHEWADHARHRGVAAVFQAAQLAGMGRRVLSQRGGERDLTDLAHIAQL LHEAAHRERLGLPGLRDWLRRQAKAGAGPPEHNRRLDSDAAAVQIMTVFVAKGLQFPIVYLPFAFNRNVRSDDILLYHDD GTRCLYIGGKDGGAQRRTVEGLNRVEAAHDNLRLTYVALTRAQSQVVAWWAPTFDEVNGGLSRLLRGRRPGQSQVPDRCT PRVTDEQAWAVFAQWEAAGGPSVEESVIGARSSLEKPVPVPGFEVRHFHRRIDTTWRRTSYSDLVRGSEAVTVTSEPAAG GRADEVEIAVFAAPGSGADLTSPLAALPSGASFGSLVHAVLETADPAAPDLAAELEAQVPGTRRGGPWTSTTRSWLPNWP ERCCRCTTRRWDPPPPH
Specific function: Required for efficient DNA repair; it catalyzes the unwinding of double-stranded DNA and the cleavage of single- stranded DNA and it stimulates local genetic recombination. All of these activities require concomitant hydrolysis of ATP [H]
COG id: COG1074
COG function: function code L; ATP-dependent exoDNAse (exonuclease V) beta subunit (contains helicase and exonuclease domains)
Gene ontology:
Cell location: Cytoplasm [C]
Metaboloic importance: Unknown [C]
Operon status: Not Known
Operon components: None
Similarity: Contains 1 uvrD-like helicase C-terminal domain [H]
Homologues:
Organism=Escherichia coli, GI1789183, Length=670, Percent_Identity=30.5970149253731, Blast_Score=220, Evalue=3e-58,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR014017 - InterPro: IPR000212 - InterPro: IPR004586 - InterPro: IPR011604 - InterPro: IPR014016 - InterPro: IPR011335 [H]
Pfam domain/function: PF00580 UvrD-helicase [H]
EC number: =3.1.11.5 [H]
Molecular weight: Translated: 97533; Mature: 97533
Theoretical pI: Translated: 6.58; Mature: 6.58
Prosite motif: NA
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
1.1 %Cys (Translated Protein) 0.8 %Met (Translated Protein) 1.9 %Cys+Met (Translated Protein) 1.1 %Cys (Mature Protein) 0.8 %Met (Mature Protein) 1.9 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MDRFELLGPLPREGTTTVLEASAGTGKTFALAGLVTRYLAETAATLDEMLLITFNRAASR CCCCHHCCCCCCCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHH ELRERVRGQIVEALGALQGDAPPSGELVEHLLRGSDAERAQKRSRLRDALANFDAATIAT HHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCHHHHHH THEFCGSVLKSLGVAGDNAADVELKESLTDLVTEIVDDRYLANFGRQETDPELTYAEALA HHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHH LALAVVDDPCAQLRPPDPEPGSKAAVRLRFAAEVLEELERRKGRLRAQGFNDLLIRLATA HHHHHHCCCHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCHHCCHHHHHHHHHHH LEAADSPARDRMRERWRIVLVDEFQDTDPMQWRVLERAFSRHSALILIGDPKQAIYGFRG HHHCCCCHHHHHHHCCEEEEEECCCCCCCHHHHHHHHHHHCCCEEEEECCCHHHHCCCCC GDIHTYLKAAGTADARYTLGVNWRSDRALVESLQTVLRDATLGHADIVVRGTDAHHAGHR CCHHHHHHHCCCCCCEEEEECCCCCHHHHHHHHHHHHHHCCCCCCEEEEECCCCHHHHHH LASAPRPAPFRLRVVKRHTLGYDGTAHVPIEALRRHIPDDLAADVAALLASGATFAGRPV HHCCCCCCCEEEEEEEHHHCCCCCCCCCCHHHHHHHCCHHHHHHHHHHHHCCCCCCCCCH VAADIAVIVEHHKDARACRNALAEAGIPAIYTGDTDVFASQAAKDWLCLLEAFDAPQRSG HHHHHHHHHHHCHHHHHHHHHHHHCCCCEEEECCHHHHHHHHHHHHHHHHHHHCCCHHCC LVRAAACTMFFGETAESLAAEGDALTDRVAGTLHEWADHARHRGVAAVFQAAQLAGMGRR CHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHH VLSQRGGERDLTDLAHIAQLLHEAAHRERLGLPGLRDWLRRQAKAGAGPPEHNRRLDSDA HHHHCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCCCHHCCCCCCHH AAVQIMTVFVAKGLQFPIVYLPFAFNRNVRSDDILLYHDDGTRCLYIGGKDGGAQRRTVE HHHHHHHHHHHCCCCCCEEEEEEECCCCCCCCCEEEEECCCCEEEEEECCCCCCHHHHHH GLNRVEAAHDNLRLTYVALTRAQSQVVAWWAPTFDEVNGGLSRLLRGRRPGQSQVPDRCT HHHHHHHHCCCEEEEEEEEECCCCCEEEEECCCHHHHHHHHHHHHHCCCCCCCCCCCCCC PRVTDEQAWAVFAQWEAAGGPSVEESVIGARSSLEKPVPVPGFEVRHFHRRIDTTWRRTS CCCCCCHHEEEEEEEECCCCCCHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHCC YSDLVRGSEAVTVTSEPAAGGRADEVEIAVFAAPGSGADLTSPLAALPSGASFGSLVHAV HHHHHCCCCEEEEECCCCCCCCCCCEEEEEEECCCCCCCCCCHHHHCCCCCHHHHHHHHH LETADPAAPDLAAELEAQVPGTRRGGPWTSTTRSWLPNWPERCCRCTTRRWDPPPPH HHHCCCCCCCHHHHHHHCCCCCCCCCCCCCCHHHCCCCHHHHHHHHHCCCCCCCCCC >Mature Secondary Structure MDRFELLGPLPREGTTTVLEASAGTGKTFALAGLVTRYLAETAATLDEMLLITFNRAASR CCCCHHCCCCCCCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHH ELRERVRGQIVEALGALQGDAPPSGELVEHLLRGSDAERAQKRSRLRDALANFDAATIAT HHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCHHHHHH THEFCGSVLKSLGVAGDNAADVELKESLTDLVTEIVDDRYLANFGRQETDPELTYAEALA HHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHH LALAVVDDPCAQLRPPDPEPGSKAAVRLRFAAEVLEELERRKGRLRAQGFNDLLIRLATA HHHHHHCCCHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCHHCCHHHHHHHHHHH LEAADSPARDRMRERWRIVLVDEFQDTDPMQWRVLERAFSRHSALILIGDPKQAIYGFRG HHHCCCCHHHHHHHCCEEEEEECCCCCCCHHHHHHHHHHHCCCEEEEECCCHHHHCCCCC GDIHTYLKAAGTADARYTLGVNWRSDRALVESLQTVLRDATLGHADIVVRGTDAHHAGHR CCHHHHHHHCCCCCCEEEEECCCCCHHHHHHHHHHHHHHCCCCCCEEEEECCCCHHHHHH LASAPRPAPFRLRVVKRHTLGYDGTAHVPIEALRRHIPDDLAADVAALLASGATFAGRPV HHCCCCCCCEEEEEEEHHHCCCCCCCCCCHHHHHHHCCHHHHHHHHHHHHCCCCCCCCCH VAADIAVIVEHHKDARACRNALAEAGIPAIYTGDTDVFASQAAKDWLCLLEAFDAPQRSG HHHHHHHHHHHCHHHHHHHHHHHHCCCCEEEECCHHHHHHHHHHHHHHHHHHHCCCHHCC LVRAAACTMFFGETAESLAAEGDALTDRVAGTLHEWADHARHRGVAAVFQAAQLAGMGRR CHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHH VLSQRGGERDLTDLAHIAQLLHEAAHRERLGLPGLRDWLRRQAKAGAGPPEHNRRLDSDA HHHHCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCCCHHCCCCCCHH AAVQIMTVFVAKGLQFPIVYLPFAFNRNVRSDDILLYHDDGTRCLYIGGKDGGAQRRTVE HHHHHHHHHHHCCCCCCEEEEEEECCCCCCCCCEEEEECCCCEEEEEECCCCCCHHHHHH GLNRVEAAHDNLRLTYVALTRAQSQVVAWWAPTFDEVNGGLSRLLRGRRPGQSQVPDRCT HHHHHHHHCCCEEEEEEEEECCCCCEEEEECCCHHHHHHHHHHHHHCCCCCCCCCCCCCC PRVTDEQAWAVFAQWEAAGGPSVEESVIGARSSLEKPVPVPGFEVRHFHRRIDTTWRRTS CCCCCCHHEEEEEEEECCCCCCHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHCC YSDLVRGSEAVTVTSEPAAGGRADEVEIAVFAAPGSGADLTSPLAALPSGASFGSLVHAV HHHHHCCCCEEEEECCCCCCCCCCCEEEEEEECCCCCCCCCCHHHHCCCCCHHHHHHHHH LETADPAAPDLAAELEAQVPGTRRGGPWTSTTRSWLPNWPERCCRCTTRRWDPPPPH HHHCCCCCCCHHHHHHHCCCCCCCCCCCCCCHHHCCCCHHHHHHHHHCCCCCCCCCC
PDB accession: NA
Resolution: NA
Structure class: Unstructured
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 9.0
TargetDB status: NA
Availability: NA
References: 9634230; 12218036 [H]