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The map label for this gene is mmpL1a [H]

Identifier: 121636315

GI number: 121636315

Start: 512270

End: 514045

Strand: Reverse

Name: mmpL1a [H]

Synonym: BCG_0440c

Alternate gene names: 121636315

Gene position: 514045-512270 (Counterclockwise)

Preceding gene: 121636316

Following gene: 121636314

Centisome position: 11.75

GC content: 60.42

Gene sequence:

>1776_bases
GTGAGGAGCCAACGTCTAGCCGGGCACCTGTCGGCCGCCGCCCGGACGATCCATGCGTTGTCGCTACCCATCATTCTGTT
CTGGGTGGCGCTGACTATTGTGGTGAACGTCGTTGCGCCGCAGCTACAGTCGGTCGCTAGGACACATTCGGTGGCGTTAG
GCCCCCACGATGCTCCGTCACTGATCGCCATGAAGCGCATCGGCAAGGACTTTCAGCAATTCGATTCTGACACCACTGCA
ATGGTGCTGCTGGAGGGCCAAGAGAAGCTGGGTGATGAGGCGCACCGCTTCTATGACGTGCTAGTGACCAAGCTGTCACA
AGACACCACCCACGTCCAACACATTGAGAACTTCTGGGGCGATCCGCTGACCGCGGCGGGATCGCAGAGCGCTGACGGCA
AGGCAGCATATGTCCAGCTGAACCTCACTGGTGATCAGGGCGGCTCGCAGGCCAACGAGTCTGTCGCCGCCGTGCAACGC
ATCGTGGACAGCGTGCCACCGCCGCCGGGGATCAAGGCTTACGTGACAGGCCCGGGTCCACTCGGCGCCGATCGAGTTGT
ATACGGCGACCGCAGCCTTCACACGATTACCGGCATCAGCATTGCGGTGATCGCGATCATGTTGTTCATCGCCTACCGCT
CGCTTTCTGCTGCTCTGATCATGCTGCTGACGGTCGGGCTCGAGCTGCTGGCGGTCCGCGGCATCATCTCCACTTTTGCC
GTCAACGACCTCATGGGCCTGTCTACATTCACTGTCAACGTGTTGGTGGCGCTCACGATCGCGGCTTCGACGGACTACAT
CATCTTTCTCGTCGGACGCTATCAAGAGGCACGTGCGACTGGCCAGAACCGAGAAGCCGCTTACTACACCATGTTTGGTG
GGACGGCACACGTGGTCCTGGCATCTGGCCTCACCGTCGCCGGCGCCATGTACTGCCTCGGCTTTACCCGGCTACCCTAC
TTCAATACCCTCGCATCGCCATGCGCGATCGGTTTGGTCACGGTGATGTTGGCGTCTCTGACGCTGGCGCCCGCGATCAT
CGCCGTTGCCAGCCGATTCGGGCTATTCGACCCCAAACGAGCGACAACGAAACGGCGTTGGCGCCGGATCGGCACGGTCG
TCGTGCGATGGCCCGGCCCCGTCTTGGCCGCCACCCTGCTGATAGCGCTGATCGGACTGCTCGCCTTGCCGAAATACCAG
ACCAACTACAACGAGCGCTACTACATCCCCAGCGCGGCGCCATCCAACATCGGTTACCTCGCATCAGACCGTCACTTTCC
GCAAGCCCGCATGGAACCGGAGGTCCTGATGGTCGAGGCCGATCACGACCTGCGTAACCCGACCGACATGCCCATCCTGG
ACAGGATCGCCAAAACCGTCTTCCATACGCCGGGGATCGCGCGGGTGCAAAGCATTACCAGACCGTTGGGGGCTCCGATC
GACCACTCGTCGATCCCGTTTCAGCTCGGCATGCAAAGCACGATGACCATCGAAAACCTGCAGAACCTCAAGGACCGCGT
GGCTGATCTATCCACCCTTACCGATCAACTGCAACGCATGATCGACATCACCCAGCGAACCCAGGAGCTGACGCGACAGC
TAACCGATGCCACCCATGATATGAACGCTCATACCAGGCAGATGCGAGACAACGCCAACGAACTACGCGATCGAATCGCC
GATTTCGACGACTTCTGGCGCCCCTCAGAAGTTTCACGTACTGGGAGCGCCACTGCTTCGACATTCCCATCTGCTGGTCG
ATGCGCTCCTTGTTGA

Upstream 100 bases:

>100_bases
GTGCAAGCCTGGGCTGTCGCATCACTGTCAACGAGGTGATCCGCGAGGAGCGCATTGTGAATGCTTACCACGCGCACACC
AGTTGCCTGGTGAAATCCGC

Downstream 100 bases:

>100_bases
ACAGCATGGATAACGTCGACAAGCTCACCGAGGACCTTGCCAACCTCACCGACGACACCGAACGCATGGACACCACACAG
CGGCAACTACTCGCCCAACT

Product: putative transmembrane transport protein mmpL1a

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 591; Mature: 591

Protein sequence:

>591_residues
MRSQRLAGHLSAAARTIHALSLPIILFWVALTIVVNVVAPQLQSVARTHSVALGPHDAPSLIAMKRIGKDFQQFDSDTTA
MVLLEGQEKLGDEAHRFYDVLVTKLSQDTTHVQHIENFWGDPLTAAGSQSADGKAAYVQLNLTGDQGGSQANESVAAVQR
IVDSVPPPPGIKAYVTGPGPLGADRVVYGDRSLHTITGISIAVIAIMLFIAYRSLSAALIMLLTVGLELLAVRGIISTFA
VNDLMGLSTFTVNVLVALTIAASTDYIIFLVGRYQEARATGQNREAAYYTMFGGTAHVVLASGLTVAGAMYCLGFTRLPY
FNTLASPCAIGLVTVMLASLTLAPAIIAVASRFGLFDPKRATTKRRWRRIGTVVVRWPGPVLAATLLIALIGLLALPKYQ
TNYNERYYIPSAAPSNIGYLASDRHFPQARMEPEVLMVEADHDLRNPTDMPILDRIAKTVFHTPGIARVQSITRPLGAPI
DHSSIPFQLGMQSTMTIENLQNLKDRVADLSTLTDQLQRMIDITQRTQELTRQLTDATHDMNAHTRQMRDNANELRDRIA
DFDDFWRPSEVSRTGSATASTFPSAGRCAPC

Sequences:

>Translated_591_residues
MRSQRLAGHLSAAARTIHALSLPIILFWVALTIVVNVVAPQLQSVARTHSVALGPHDAPSLIAMKRIGKDFQQFDSDTTA
MVLLEGQEKLGDEAHRFYDVLVTKLSQDTTHVQHIENFWGDPLTAAGSQSADGKAAYVQLNLTGDQGGSQANESVAAVQR
IVDSVPPPPGIKAYVTGPGPLGADRVVYGDRSLHTITGISIAVIAIMLFIAYRSLSAALIMLLTVGLELLAVRGIISTFA
VNDLMGLSTFTVNVLVALTIAASTDYIIFLVGRYQEARATGQNREAAYYTMFGGTAHVVLASGLTVAGAMYCLGFTRLPY
FNTLASPCAIGLVTVMLASLTLAPAIIAVASRFGLFDPKRATTKRRWRRIGTVVVRWPGPVLAATLLIALIGLLALPKYQ
TNYNERYYIPSAAPSNIGYLASDRHFPQARMEPEVLMVEADHDLRNPTDMPILDRIAKTVFHTPGIARVQSITRPLGAPI
DHSSIPFQLGMQSTMTIENLQNLKDRVADLSTLTDQLQRMIDITQRTQELTRQLTDATHDMNAHTRQMRDNANELRDRIA
DFDDFWRPSEVSRTGSATASTFPSAGRCAPC
>Mature_591_residues
MRSQRLAGHLSAAARTIHALSLPIILFWVALTIVVNVVAPQLQSVARTHSVALGPHDAPSLIAMKRIGKDFQQFDSDTTA
MVLLEGQEKLGDEAHRFYDVLVTKLSQDTTHVQHIENFWGDPLTAAGSQSADGKAAYVQLNLTGDQGGSQANESVAAVQR
IVDSVPPPPGIKAYVTGPGPLGADRVVYGDRSLHTITGISIAVIAIMLFIAYRSLSAALIMLLTVGLELLAVRGIISTFA
VNDLMGLSTFTVNVLVALTIAASTDYIIFLVGRYQEARATGQNREAAYYTMFGGTAHVVLASGLTVAGAMYCLGFTRLPY
FNTLASPCAIGLVTVMLASLTLAPAIIAVASRFGLFDPKRATTKRRWRRIGTVVVRWPGPVLAATLLIALIGLLALPKYQ
TNYNERYYIPSAAPSNIGYLASDRHFPQARMEPEVLMVEADHDLRNPTDMPILDRIAKTVFHTPGIARVQSITRPLGAPI
DHSSIPFQLGMQSTMTIENLQNLKDRVADLSTLTDQLQRMIDITQRTQELTRQLTDATHDMNAHTRQMRDNANELRDRIA
DFDDFWRPSEVSRTGSATASTFPSAGRCAPC

Specific function: Unknown

COG id: COG2409

COG function: function code R; Predicted drug exporters of the RND superfamily

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the mmpL family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004707
- InterPro:   IPR004869 [H]

Pfam domain/function: PF03176 MMPL [H]

EC number: NA

Molecular weight: Translated: 64260; Mature: 64260

Theoretical pI: Translated: 8.32; Mature: 8.32

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRSQRLAGHLSAAARTIHALSLPIILFWVALTIVVNVVAPQLQSVARTHSVALGPHDAPS
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCCCHH
LIAMKRIGKDFQQFDSDTTAMVLLEGQEKLGDEAHRFYDVLVTKLSQDTTHVQHIENFWG
HHHHHHHHHHHHHHCCCCEEEEEECCHHHHCHHHHHHHHHHHHHHCCCHHHHHHHHHHCC
DPLTAAGSQSADGKAAYVQLNLTGDQGGSQANESVAAVQRIVDSVPPPPGIKAYVTGPGP
CCCCCCCCCCCCCCEEEEEEEEECCCCCCHHHHHHHHHHHHHHCCCCCCCCEEEEECCCC
LGADRVVYGDRSLHTITGISIAVIAIMLFIAYRSLSAALIMLLTVGLELLAVRGIISTFA
CCCCCEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VNDLMGLSTFTVNVLVALTIAASTDYIIFLVGRYQEARATGQNREAAYYTMFGGTAHVVL
HHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCHHHHHCCCCCCCEEEEEECCCEEHHH
ASGLTVAGAMYCLGFTRLPYFNTLASPCAIGLVTVMLASLTLAPAIIAVASRFGLFDPKR
HCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHH
ATTKRRWRRIGTVVVRWPGPVLAATLLIALIGLLALPKYQTNYNERYYIPSAAPSNIGYL
HHHHHHHHHHCEEEEECCCHHHHHHHHHHHHHHHHCCCCCCCCCCEEEECCCCCCCCCCC
ASDRHFPQARMEPEVLMVEADHDLRNPTDMPILDRIAKTVFHTPGIARVQSITRPLGAPI
CCCCCCCCCCCCCCEEEEECCCCCCCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHCCCCC
DHSSIPFQLGMQSTMTIENLQNLKDRVADLSTLTDQLQRMIDITQRTQELTRQLTDATHD
CCCCCCHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
MNAHTRQMRDNANELRDRIADFDDFWRPSEVSRTGSATASTFPSAGRCAPC
CHHHHHHHHCCHHHHHHHHCCHHHCCCCCHHCCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MRSQRLAGHLSAAARTIHALSLPIILFWVALTIVVNVVAPQLQSVARTHSVALGPHDAPS
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCCCHH
LIAMKRIGKDFQQFDSDTTAMVLLEGQEKLGDEAHRFYDVLVTKLSQDTTHVQHIENFWG
HHHHHHHHHHHHHHCCCCEEEEEECCHHHHCHHHHHHHHHHHHHHCCCHHHHHHHHHHCC
DPLTAAGSQSADGKAAYVQLNLTGDQGGSQANESVAAVQRIVDSVPPPPGIKAYVTGPGP
CCCCCCCCCCCCCCEEEEEEEEECCCCCCHHHHHHHHHHHHHHCCCCCCCCEEEEECCCC
LGADRVVYGDRSLHTITGISIAVIAIMLFIAYRSLSAALIMLLTVGLELLAVRGIISTFA
CCCCCEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VNDLMGLSTFTVNVLVALTIAASTDYIIFLVGRYQEARATGQNREAAYYTMFGGTAHVVL
HHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCHHHHHCCCCCCCEEEEEECCCEEHHH
ASGLTVAGAMYCLGFTRLPYFNTLASPCAIGLVTVMLASLTLAPAIIAVASRFGLFDPKR
HCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHH
ATTKRRWRRIGTVVVRWPGPVLAATLLIALIGLLALPKYQTNYNERYYIPSAAPSNIGYL
HHHHHHHHHHCEEEEECCCHHHHHHHHHHHHHHHHCCCCCCCCCCEEEECCCCCCCCCCC
ASDRHFPQARMEPEVLMVEADHDLRNPTDMPILDRIAKTVFHTPGIARVQSITRPLGAPI
CCCCCCCCCCCCCCEEEEECCCCCCCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHCCCCC
DHSSIPFQLGMQSTMTIENLQNLKDRVADLSTLTDQLQRMIDITQRTQELTRQLTDATHD
CCCCCCHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
MNAHTRQMRDNANELRDRIADFDDFWRPSEVSRTGSATASTFPSAGRCAPC
CHHHHHHHHCCHHHHHHHHCCHHHCCCCCHHCCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036 [H]