Click here to switch to the map view.

The map label for this gene is ycbL [H]

Identifier: 120612957

GI number: 120612957

Start: 4799677

End: 4800423

Strand: Reverse

Name: ycbL [H]

Synonym: Aave_4321

Alternate gene names: 120612957

Gene position: 4800423-4799677 (Counterclockwise)

Preceding gene: 120612967

Following gene: 120612956

Centisome position: 89.68

GC content: 72.69

Gene sequence:

>747_bases
ATGAACCTTCCCGCTGCCCCGCAGGCCACCGGCCCGCTCGTTCTCGTGGTCGAGGACGAGCCCGGCATCGCCACCATCCT
TTCCGCCTATCTCCAGCGCGACGGGCTGCGCGCCCGCCAGGCCCACGACGGTCTGGAGGCATTGCGGCTGTTCCGCCAGC
TCAAGCCCGACATGGTGCTGCTGGACATCCACCTGCCCGGCATGGACGGCCTGGACCTGCTGCGCGCGATCCGCGAGGAC
GGCCAGACGCCGGTGATCATGGTGACGGCCCTGGCCGACGACGTGGACAAGCTGGTCGGGCTGCGCCTGGGGGCGGACGA
CTACGTGGTCAAGCCTTTCAGCCCGCCGGAGGTGGTGGCCCGCGTGCGCGCCGTGCTGCGGCGCGCACAGGCCCAGCCCG
CGGCGCCGGCACGGGCCGCCCAGCGCATCCGCGTGGGCCGCATCGAGATCGACCAGGAGGCGCACGCCGCCTTCGCCCAT
GGCGACGACGGGCGCGCCGTGCCCCTGCCGCTGACGCTGACCGAATACCGGCTGCTGGCCTGCCTGGCGGCGCAGCCCCG
GCGCTGCTTCTCCCGCAGCCACCTGATCGAGCACTGCCTTCCCGAGAGCGACGCGCTGGACCGCGTGATCGATTCCCACC
TCTCCAAGCTGCGCCGCAAGCTGCAGCAGGCGGGGCAGGGCGAGCTCATCGAGACCGTGCGCGGCATCGGCTACCGGCTC
TGGCCCGGGGAGGGTACCGTTGCCTGA

Upstream 100 bases:

>100_bases
CCGCCTTGCATGGCATATGGAGGCTTCATGGAGACGCCGGGCTTTGTCCTGCAGGTCGGCGGCCGCTGTGGATAATTCCG
CCCCAGCACTTCCCGACGCC

Downstream 100 bases:

>100_bases
GCACCGCGCACCGGCCGTGCAGGGGTCGCTGTTCAGCCGGGTCTGGGTGCGCTTCGGCGTGTGCATCGCCGCCACCGTGC
TGGCGACGATGGCCCTGCTC

Product: two component transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 248; Mature: 248

Protein sequence:

>248_residues
MNLPAAPQATGPLVLVVEDEPGIATILSAYLQRDGLRARQAHDGLEALRLFRQLKPDMVLLDIHLPGMDGLDLLRAIRED
GQTPVIMVTALADDVDKLVGLRLGADDYVVKPFSPPEVVARVRAVLRRAQAQPAAPARAAQRIRVGRIEIDQEAHAAFAH
GDDGRAVPLPLTLTEYRLLACLAAQPRRCFSRSHLIEHCLPESDALDRVIDSHLSKLRRKLQQAGQGELIETVRGIGYRL
WPGEGTVA

Sequences:

>Translated_248_residues
MNLPAAPQATGPLVLVVEDEPGIATILSAYLQRDGLRARQAHDGLEALRLFRQLKPDMVLLDIHLPGMDGLDLLRAIRED
GQTPVIMVTALADDVDKLVGLRLGADDYVVKPFSPPEVVARVRAVLRRAQAQPAAPARAAQRIRVGRIEIDQEAHAAFAH
GDDGRAVPLPLTLTEYRLLACLAAQPRRCFSRSHLIEHCLPESDALDRVIDSHLSKLRRKLQQAGQGELIETVRGIGYRL
WPGEGTVA
>Mature_248_residues
MNLPAAPQATGPLVLVVEDEPGIATILSAYLQRDGLRARQAHDGLEALRLFRQLKPDMVLLDIHLPGMDGLDLLRAIRED
GQTPVIMVTALADDVDKLVGLRLGADDYVVKPFSPPEVVARVRAVLRRAQAQPAAPARAAQRIRVGRIEIDQEAHAAFAH
GDDGRAVPLPLTLTEYRLLACLAAQPRRCFSRSHLIEHCLPESDALDRVIDSHLSKLRRKLQQAGQGELIETVRGIGYRL
WPGEGTVA

Specific function: Member of the two-component regulatory system ycbM/ycbL [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1788394, Length=238, Percent_Identity=39.4957983193277, Blast_Score=156, Evalue=1e-39,
Organism=Escherichia coli, GI1786599, Length=231, Percent_Identity=35.0649350649351, Blast_Score=147, Evalue=5e-37,
Organism=Escherichia coli, GI1789809, Length=233, Percent_Identity=36.480686695279, Blast_Score=141, Evalue=4e-35,
Organism=Escherichia coli, GI1790860, Length=230, Percent_Identity=39.5652173913043, Blast_Score=137, Evalue=9e-34,
Organism=Escherichia coli, GI2367329, Length=230, Percent_Identity=37.3913043478261, Blast_Score=122, Evalue=3e-29,
Organism=Escherichia coli, GI1790863, Length=233, Percent_Identity=30.0429184549356, Blast_Score=117, Evalue=9e-28,
Organism=Escherichia coli, GI1789402, Length=230, Percent_Identity=36.0869565217391, Blast_Score=110, Evalue=7e-26,
Organism=Escherichia coli, GI1787229, Length=231, Percent_Identity=32.4675324675325, Blast_Score=103, Evalue=1e-23,
Organism=Escherichia coli, GI1786784, Length=229, Percent_Identity=31.4410480349345, Blast_Score=102, Evalue=3e-23,
Organism=Escherichia coli, GI87082012, Length=230, Percent_Identity=31.7391304347826, Blast_Score=100, Evalue=1e-22,
Organism=Escherichia coli, GI1786911, Length=229, Percent_Identity=31.0043668122271, Blast_Score=99, Evalue=2e-22,
Organism=Escherichia coli, GI1787375, Length=227, Percent_Identity=32.5991189427313, Blast_Score=96, Evalue=3e-21,
Organism=Escherichia coli, GI145693140, Length=241, Percent_Identity=28.6307053941909, Blast_Score=91, Evalue=5e-20,
Organism=Escherichia coli, GI1790552, Length=239, Percent_Identity=32.6359832635983, Blast_Score=86, Evalue=2e-18,
Organism=Escherichia coli, GI1788550, Length=106, Percent_Identity=40.5660377358491, Blast_Score=82, Evalue=3e-17,
Organism=Escherichia coli, GI1787487, Length=104, Percent_Identity=38.4615384615385, Blast_Score=73, Evalue=1e-14,
Organism=Escherichia coli, GI1790299, Length=121, Percent_Identity=37.1900826446281, Blast_Score=69, Evalue=3e-13,
Organism=Escherichia coli, GI1788191, Length=118, Percent_Identity=33.8983050847458, Blast_Score=66, Evalue=2e-12,
Organism=Escherichia coli, GI1788521, Length=141, Percent_Identity=31.9148936170213, Blast_Score=61, Evalue=8e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001867
- InterPro:   IPR001789
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00072 Response_reg; PF00486 Trans_reg_C [H]

EC number: NA

Molecular weight: Translated: 27160; Mature: 27160

Theoretical pI: Translated: 7.20; Mature: 7.20

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNLPAAPQATGPLVLVVEDEPGIATILSAYLQRDGLRARQAHDGLEALRLFRQLKPDMVL
CCCCCCCCCCCCEEEEEECCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCEEE
LDIHLPGMDGLDLLRAIREDGQTPVIMVTALADDVDKLVGLRLGADDYVVKPFSPPEVVA
EEEECCCCCHHHHHHHHHHCCCCCEEEEEHHHHHHHHHHHHEECCCCCEECCCCCHHHHH
RVRAVLRRAQAQPAAPARAAQRIRVGRIEIDQEAHAAFAHGDDGRAVPLPLTLTEYRLLA
HHHHHHHHHCCCCCCHHHHHHHHHHCCEEECHHHHHHHEECCCCCEEECCCHHHHHHHHH
CLAAQPRRCFSRSHLIEHCLPESDALDRVIDSHLSKLRRKLQQAGQGELIETVRGIGYRL
HHHHCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCEEE
WPGEGTVA
ECCCCCCC
>Mature Secondary Structure
MNLPAAPQATGPLVLVVEDEPGIATILSAYLQRDGLRARQAHDGLEALRLFRQLKPDMVL
CCCCCCCCCCCCEEEEEECCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCEEE
LDIHLPGMDGLDLLRAIREDGQTPVIMVTALADDVDKLVGLRLGADDYVVKPFSPPEVVA
EEEECCCCCHHHHHHHHHHCCCCCEEEEEHHHHHHHHHHHHEECCCCCEECCCCCHHHHH
RVRAVLRRAQAQPAAPARAAQRIRVGRIEIDQEAHAAFAHGDDGRAVPLPLTLTEYRLLA
HHHHHHHHHCCCCCCHHHHHHHHHHCCEEECHHHHHHHEECCCCCEEECCCHHHHHHHHH
CLAAQPRRCFSRSHLIEHCLPESDALDRVIDSHLSKLRRKLQQAGQGELIETVRGIGYRL
HHHHCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCEEE
WPGEGTVA
ECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7704254; 9384377 [H]