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The map label for this gene is trg [H]

Identifier: 120612930

GI number: 120612930

Start: 4766839

End: 4768458

Strand: Direct

Name: trg [H]

Synonym: Aave_4294

Alternate gene names: 120612930

Gene position: 4766839-4768458 (Clockwise)

Preceding gene: 120612926

Following gene: 120612933

Centisome position: 89.05

GC content: 70.99

Gene sequence:

>1620_bases
ATGCAGGCCGTCACATTCCTTCGCTCCCTCTCGATTTCGCGCCGGCTGTTCCTCGGCTTCGGATGCATGCTGGCCTTGCT
GGTGGCCGTGGCGGCCCTGGGCCACTTCTCCATGTCGGGCATGAACCGGCAGATGCAGCAGATCACCGGCCCGGGCGCAG
CCAAGGCCCGGCTGGCCAACGACATGCTGCAGACCGTGAGCGCCACGGGCATCCATGCGCGCTCGGCCGCGATGCTGGGC
GACATCGACAGCCGCAATGCCGAGGTCCAGGCCCGCAAGGCATCCGAAGCCCTGCAGCAGTACGCCCGGCAGGAGGCCGA
ACTCGCGGCGCTGCTGGAGTCCGGCGGCGCGTCGCCCGAGGAGCGCCAGCTGATGGCGGACATCCAGGCACAGTCCCGCA
AGACCCGCCCCGAGATCGAAGGCGCGCTCAAGCTGGTCACCGACGGCGACACGGTCAGCGCCACCCTCGGCCTGATGACC
CGCGTGGCGCCGCCCGAGGCGGCATGGCGCGACAAGCTGGCGCAACTGGTGGAGCTGCACAACGTCCTCAACGCCAACGC
CGCGGCCGACGCGCAGCAGACCCAGACCCGCTCGCGCCTGACCGGCGGCACGCTGGTGGCCATCGCCATCGCCCTGGGCC
TGTTCATCGCCTGGCGCACCACGGCCACCATCACCCAGCCCATCGGGCGGGCCGTCGTCGTGGCCGAGCGCATCGCGCGC
GGGGATCTCACCTCCCGCGTGGAAGTCCGCATCCACGACGAGACCGGACGCCTGCTGGACGCGATCGCGGCGATGCAGGA
GCAGTTGCGCGCCCTCGTGGGGCACATCGGCACCACCGCCGACTCCATCCTGCTTGCCAGTTCCGAGGTCGCATCCGGCA
ACCTGGACCTGAGCCACCGCACGGAGCAGACTTCCAGCTACCTGCAGGAGACCGCCTCCGCCCTGGAAGACCTGACCCAG
ACCGTCCACCAGGGCGCCGATGCCGCCCGGCAGGCCAACCAGATGACGGCCTCGGCCGCGCAGGTCGCCACGCGCAGCGG
CGAGGTGGTTTCCCAGGTCGTGCGCACCATGGACGTGATCAGCGCCAGTTCCCGCAAGATCTCGGACATCATCGGCGTGA
TCGACGGCATCGCCTTCCAGACCAACATCCTGGCGCTCAACGCCGCGGTGGAGGCCGCCCGCGCGGGCGAGCAGGGACGC
GGCTTCGCCGTGGTGGCAGGCGAGGTGCGCGCCCTGGCGGGGCGCAGCGCCGAAGCCGCCCGCGAGATCAAGGCGCTGAT
CCTCGCCAGCTCCGGGCAGGTGCAGGAAGGCTCCGGCCTCGTCGCCCAGGCGGGTGCCACCATCGGGGAACTCGTGCAAT
CCGTGCAGAAGGTGTCGTCCATCATGGGAGAGATCACCACCTCGGCCCACGAGCAGAGCGACCGCATCGGCCAGGTGAGC
CAGTCCGTGAGCGCCCTGGAGAACATGACCCAGCAGAACGCCGCGCTGGTGGAGGAAAGCAGCGCGGCGGCGGGCAGCCT
GCGCGAGCAGGCCGGCCGCCTGACCGAGATGGTGGGAGCCTTCCGCCTGCAGCGCGACGCCTCGGGCGCCGCTCCACTCA
CGCCCGCGCTGCCGGGCTGA

Upstream 100 bases:

>100_bases
GCCGTGGATGCGCCCCTCATTTGTAACAACACCGGGTTTTCTACTGGCACTCATCTTGCGATGAACCCCTGACATCGGAC
CAAGCTACCAGAAACACACT

Downstream 100 bases:

>100_bases
CCGCCCGGCGGGCCGCCCCGCCCCGCCGCCCCCTGGTCCGCGGGTGCGAGGCCAGCGGCTCGCCGGCACCGAAAACGCTG
TCGCGCAGCGCGGGAAGGTC

Product: methyl-accepting chemotaxis sensory transducer

Products: NA

Alternate protein names: MCP-III; Ribose and galactose chemoreceptor protein [H]

Number of amino acids: Translated: 539; Mature: 539

Protein sequence:

>539_residues
MQAVTFLRSLSISRRLFLGFGCMLALLVAVAALGHFSMSGMNRQMQQITGPGAAKARLANDMLQTVSATGIHARSAAMLG
DIDSRNAEVQARKASEALQQYARQEAELAALLESGGASPEERQLMADIQAQSRKTRPEIEGALKLVTDGDTVSATLGLMT
RVAPPEAAWRDKLAQLVELHNVLNANAAADAQQTQTRSRLTGGTLVAIAIALGLFIAWRTTATITQPIGRAVVVAERIAR
GDLTSRVEVRIHDETGRLLDAIAAMQEQLRALVGHIGTTADSILLASSEVASGNLDLSHRTEQTSSYLQETASALEDLTQ
TVHQGADAARQANQMTASAAQVATRSGEVVSQVVRTMDVISASSRKISDIIGVIDGIAFQTNILALNAAVEAARAGEQGR
GFAVVAGEVRALAGRSAEAAREIKALILASSGQVQEGSGLVAQAGATIGELVQSVQKVSSIMGEITTSAHEQSDRIGQVS
QSVSALENMTQQNAALVEESSAAAGSLREQAGRLTEMVGAFRLQRDASGAAPLTPALPG

Sequences:

>Translated_539_residues
MQAVTFLRSLSISRRLFLGFGCMLALLVAVAALGHFSMSGMNRQMQQITGPGAAKARLANDMLQTVSATGIHARSAAMLG
DIDSRNAEVQARKASEALQQYARQEAELAALLESGGASPEERQLMADIQAQSRKTRPEIEGALKLVTDGDTVSATLGLMT
RVAPPEAAWRDKLAQLVELHNVLNANAAADAQQTQTRSRLTGGTLVAIAIALGLFIAWRTTATITQPIGRAVVVAERIAR
GDLTSRVEVRIHDETGRLLDAIAAMQEQLRALVGHIGTTADSILLASSEVASGNLDLSHRTEQTSSYLQETASALEDLTQ
TVHQGADAARQANQMTASAAQVATRSGEVVSQVVRTMDVISASSRKISDIIGVIDGIAFQTNILALNAAVEAARAGEQGR
GFAVVAGEVRALAGRSAEAAREIKALILASSGQVQEGSGLVAQAGATIGELVQSVQKVSSIMGEITTSAHEQSDRIGQVS
QSVSALENMTQQNAALVEESSAAAGSLREQAGRLTEMVGAFRLQRDASGAAPLTPALPG
>Mature_539_residues
MQAVTFLRSLSISRRLFLGFGCMLALLVAVAALGHFSMSGMNRQMQQITGPGAAKARLANDMLQTVSATGIHARSAAMLG
DIDSRNAEVQARKASEALQQYARQEAELAALLESGGASPEERQLMADIQAQSRKTRPEIEGALKLVTDGDTVSATLGLMT
RVAPPEAAWRDKLAQLVELHNVLNANAAADAQQTQTRSRLTGGTLVAIAIALGLFIAWRTTATITQPIGRAVVVAERIAR
GDLTSRVEVRIHDETGRLLDAIAAMQEQLRALVGHIGTTADSILLASSEVASGNLDLSHRTEQTSSYLQETASALEDLTQ
TVHQGADAARQANQMTASAAQVATRSGEVVSQVVRTMDVISASSRKISDIIGVIDGIAFQTNILALNAAVEAARAGEQGR
GFAVVAGEVRALAGRSAEAAREIKALILASSGQVQEGSGLVAQAGATIGELVQSVQKVSSIMGEITTSAHEQSDRIGQVS
QSVSALENMTQQNAALVEESSAAAGSLREQAGRLTEMVGAFRLQRDASGAAPLTPALPG

Specific function: Chemotactic-signal transducers respond to changes in the concentration of attractants and repellents in the environment, transduce a signal from the outside to the inside of the cell, and facilitate sensory adaptation through the variation of the level of

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 methyl-accepting transducer domain [H]

Homologues:

Organism=Escherichia coli, GI1787690, Length=546, Percent_Identity=37.5457875457875, Blast_Score=281, Evalue=9e-77,
Organism=Escherichia coli, GI2367378, Length=365, Percent_Identity=51.2328767123288, Blast_Score=280, Evalue=2e-76,
Organism=Escherichia coli, GI1788195, Length=312, Percent_Identity=53.2051282051282, Blast_Score=273, Evalue=2e-74,
Organism=Escherichia coli, GI1788194, Length=360, Percent_Identity=45, Blast_Score=262, Evalue=5e-71,
Organism=Escherichia coli, GI1789453, Length=295, Percent_Identity=39.6610169491525, Blast_Score=197, Evalue=1e-51,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004090
- InterPro:   IPR003122
- InterPro:   IPR004091
- InterPro:   IPR004089
- InterPro:   IPR003660 [H]

Pfam domain/function: PF00672 HAMP; PF00015 MCPsignal; PF02203 TarH [H]

EC number: NA

Molecular weight: Translated: 56336; Mature: 56336

Theoretical pI: Translated: 5.93; Mature: 5.93

Prosite motif: PS50885 HAMP ; PS00369 PTS_HPR_HIS ; PS50111 CHEMOTAXIS_TRANSDUC_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQAVTFLRSLSISRRLFLGFGCMLALLVAVAALGHFSMSGMNRQMQQITGPGAAKARLAN
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHH
DMLQTVSATGIHARSAAMLGDIDSRNAEVQARKASEALQQYARQEAELAALLESGGASPE
HHHHHHHHCCCHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHH
ERQLMADIQAQSRKTRPEIEGALKLVTDGDTVSATLGLMTRVAPPEAAWRDKLAQLVELH
HHHHHHHHHHHHCCCCCCHHHCEEEEECCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHH
NVLNANAAADAQQTQTRSRLTGGTLVAIAIALGLFIAWRTTATITQPIGRAVVVAERIAR
HHHCCCCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GDLTSRVEVRIHDETGRLLDAIAAMQEQLRALVGHIGTTADSILLASSEVASGNLDLSHR
CCCCCEEEEEEECCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHEECCCCCCCCCCCHHH
TEQTSSYLQETASALEDLTQTVHQGADAARQANQMTASAAQVATRSGEVVSQVVRTMDVI
HHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHH
SASSRKISDIIGVIDGIAFQTNILALNAAVEAARAGEQGRGFAVVAGEVRALAGRSAEAA
HCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECHHHHHHCCCHHHH
REIKALILASSGQVQEGSGLVAQAGATIGELVQSVQKVSSIMGEITTSAHEQSDRIGQVS
HHHHHHHEECCCCCCCCCCCHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QSVSALENMTQQNAALVEESSAAAGSLREQAGRLTEMVGAFRLQRDASGAAPLTPALPG
HHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCC
>Mature Secondary Structure
MQAVTFLRSLSISRRLFLGFGCMLALLVAVAALGHFSMSGMNRQMQQITGPGAAKARLAN
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHH
DMLQTVSATGIHARSAAMLGDIDSRNAEVQARKASEALQQYARQEAELAALLESGGASPE
HHHHHHHHCCCHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHH
ERQLMADIQAQSRKTRPEIEGALKLVTDGDTVSATLGLMTRVAPPEAAWRDKLAQLVELH
HHHHHHHHHHHHCCCCCCHHHCEEEEECCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHH
NVLNANAAADAQQTQTRSRLTGGTLVAIAIALGLFIAWRTTATITQPIGRAVVVAERIAR
HHHCCCCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GDLTSRVEVRIHDETGRLLDAIAAMQEQLRALVGHIGTTADSILLASSEVASGNLDLSHR
CCCCCEEEEEEECCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHEECCCCCCCCCCCHHH
TEQTSSYLQETASALEDLTQTVHQGADAARQANQMTASAAQVATRSGEVVSQVVRTMDVI
HHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHH
SASSRKISDIIGVIDGIAFQTNILALNAAVEAARAGEQGRGFAVVAGEVRALAGRSAEAA
HCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECHHHHHHCCCHHHH
REIKALILASSGQVQEGSGLVAQAGATIGELVQSVQKVSSIMGEITTSAHEQSDRIGQVS
HHHHHHHEECCCCCCCCCCCHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QSVSALENMTQQNAALVEESSAAAGSLREQAGRLTEMVGAFRLQRDASGAAPLTPALPG
HHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 6374654; 9097039; 9278503 [H]