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The map label for this gene is prpL [H]

Identifier: 120612874

GI number: 120612874

Start: 4694768

End: 4696699

Strand: Reverse

Name: prpL [H]

Synonym: Aave_4238

Alternate gene names: 120612874

Gene position: 4696699-4694768 (Counterclockwise)

Preceding gene: 120612875

Following gene: 120612873

Centisome position: 87.74

GC content: 70.7

Gene sequence:

>1932_bases
ATGGAATTCAGGCTGCGAAGTATTCGAGCGGTGATGGTGCTGGGGGCCGCGGCGCTCCTGGCGGCGTGCGGGGGTGGCGG
CGGGCCGGAGGCAGGTTCCTCCGCCTCCGTCGCGGCCGCTCCCCGGGCGGCGGTGCTGAGCGTGGAGGCGCGCGAGCAGC
CGGCCGAGGCCGCACAGGATACCGTCCGGCTCAAGGACCTGAGCGTGCGCCCCGCCTTGGCGCCTGCGCGTGTCACGCTG
GGGGCCCTGCTGGAATCGCGCAGCGGGGCGGCCGAGGCCGCCGTCGGGCCGCGCCGGATCGGGGCCGCGCGCGCCGTGGA
GGCCACGGCCACGCCTGCCGCGCTGGCCGGCCGGCTGCAATGGACGCCCACTGCGGCCGGCGGGCTCGTCGCCGCCATCA
GCTTCACTGCGCAGGACGCGCACGGCCTGCGCCTGGGCGTGCTGGTCCGGGCCCTGCCGGGCGGCGCGCAGCTGCGCGTC
TATCGCCAGGACCGTCCTTCCGCCGTGTACGAGATCTCCGGCCAGGAAGTCCTGCAGACCATCGACCGCAACATCGCCGC
GGGCGACGCGTCGGACGCGGGCCGCACCTGGTGGACGCCCGACACCGGCGGCGACGAGGCCACGCTCGAGATCGAACTGC
CGCCCGGCACGCCCGCCAGCGCCCTGGACATCGCCATCCCGCGGCTGTCGCATATCTACACCAACCTTTCCCTGCCGACG
GCGGACGAGGGCGAGCAGGCCAAGATCGGCCAGTCGGGCTCCTGCAACCTCGACTCGAGCTGCTACGACGCCTATGCCAG
CCAGCGCAACGCCGTGGCGCGCATGGTCTTCGTGCGCCCCGACGGCAATGCCTACCTCTGCACCGGCACGCTGCTCAACG
ACCGCGACGGCACGGGCACGCCGTACTTCATCTCGGCCAACCACTGCTTCTCGTCGCAGACCGTGGCCTCCACGCTGCGC
ACCGACTGGTTCTACCGCTCGCCGAGCTGCAACAGCCGCACGCTGTCGGCCAACGCCACGGCGCGCACCGGCGGCGCCAC
GCTGCTGTATGCCAACTCCAGCACCGACACGCTGTTCGTGCGGCTGAACGAAACGCCGCCGGCCGGCGCCGTGTTCGCCG
CGTGGAACGCCGGCACGCAGCCCCTCGGCAGCGCGGCGGTGGGCATCCACCATCCCCGGGGCGATCTGCAGAAGATCTCG
TTCGGCTCCATCACGTCGCTGAGCTCCTGTAGCGCACTGAGCGATTCGAGCACCAGCTTCTCCTGCAGCGGCACGTCGGG
CAACTACTACCGCGTCGGCTGGACCGACGGCGTGACCGAGGGCGGCAGCAGCGGCTCGGGCCTCTTCGTGAACGGCGCGC
TGGTCGGCACCCTCTACGGCGGCAGCGTCACCTGCACCGCACGCAACGGCTCCGACTACTACGGCCGTTTCGACGTCGCC
TACAGCGCGGCGCTGCAGCAGTGGCTCTCCCCGGTTACCAGCTCGAACGGCCGCACCGCCGTCTACCGCTTCTTCAACGG
CAGCACGGGCGCGCACTTCTACACTTCCAGCGCCGGCGAGCGCGATTTCGTGATCGCCACCTACCCGGCGTTCAGCTACG
AAGGCGTGGGCTTCTATGCCTACGGCGGCGCCACGGCCGGCCAGAGCGCGGTCTTCCGCTTATTCAACACCTCGACGGGT
GCGCACTTCTATACCATCGATGCCGGCGAGCGCGATTTCGTGCGCGCCACCTACCCGGCCTTCCAGTACGAAGGCCCCGC
GTGGTATGCCCAGACGGCGGCCGGCAACGGCTCCACGGCGATGTACCGCTTCTTCAACAAGACCACCGGCGCGCACTTCT
ACACGATCAGCCAGGGCGAGCGCGATTTCGTGATCGCGACCTACCCGGTGTTCCAGTACGAAGGCCCGGTGTACTACGCC
TGGACGAACTGA

Upstream 100 bases:

>100_bases
ACCTCCGCACACGACCATTCCGGGCGCGGCCGTGGCACATTGACGGACAGCGGCGGTGCAGGGTGCCCGCCGCAGCCAAG
ACAGGACAGGAGCTGAGGCC

Downstream 100 bases:

>100_bases
CGGCCCGGCGGCGCCAGCTCTCCTCACGTTTTCCGCATCCATGAGCATCCAGACCGACGACTTCGCCCCCGTGCCCCCGC
CCAAGCGGGTGGTCTCCGCC

Product: hypothetical protein

Products: NA

Alternate protein names: Protease IV; pvdS-regulated endoprotease [H]

Number of amino acids: Translated: 643; Mature: 643

Protein sequence:

>643_residues
MEFRLRSIRAVMVLGAAALLAACGGGGGPEAGSSASVAAAPRAAVLSVEAREQPAEAAQDTVRLKDLSVRPALAPARVTL
GALLESRSGAAEAAVGPRRIGAARAVEATATPAALAGRLQWTPTAAGGLVAAISFTAQDAHGLRLGVLVRALPGGAQLRV
YRQDRPSAVYEISGQEVLQTIDRNIAAGDASDAGRTWWTPDTGGDEATLEIELPPGTPASALDIAIPRLSHIYTNLSLPT
ADEGEQAKIGQSGSCNLDSSCYDAYASQRNAVARMVFVRPDGNAYLCTGTLLNDRDGTGTPYFISANHCFSSQTVASTLR
TDWFYRSPSCNSRTLSANATARTGGATLLYANSSTDTLFVRLNETPPAGAVFAAWNAGTQPLGSAAVGIHHPRGDLQKIS
FGSITSLSSCSALSDSSTSFSCSGTSGNYYRVGWTDGVTEGGSSGSGLFVNGALVGTLYGGSVTCTARNGSDYYGRFDVA
YSAALQQWLSPVTSSNGRTAVYRFFNGSTGAHFYTSSAGERDFVIATYPAFSYEGVGFYAYGGATAGQSAVFRLFNTSTG
AHFYTIDAGERDFVRATYPAFQYEGPAWYAQTAAGNGSTAMYRFFNKTTGAHFYTISQGERDFVIATYPVFQYEGPVYYA
WTN

Sequences:

>Translated_643_residues
MEFRLRSIRAVMVLGAAALLAACGGGGGPEAGSSASVAAAPRAAVLSVEAREQPAEAAQDTVRLKDLSVRPALAPARVTL
GALLESRSGAAEAAVGPRRIGAARAVEATATPAALAGRLQWTPTAAGGLVAAISFTAQDAHGLRLGVLVRALPGGAQLRV
YRQDRPSAVYEISGQEVLQTIDRNIAAGDASDAGRTWWTPDTGGDEATLEIELPPGTPASALDIAIPRLSHIYTNLSLPT
ADEGEQAKIGQSGSCNLDSSCYDAYASQRNAVARMVFVRPDGNAYLCTGTLLNDRDGTGTPYFISANHCFSSQTVASTLR
TDWFYRSPSCNSRTLSANATARTGGATLLYANSSTDTLFVRLNETPPAGAVFAAWNAGTQPLGSAAVGIHHPRGDLQKIS
FGSITSLSSCSALSDSSTSFSCSGTSGNYYRVGWTDGVTEGGSSGSGLFVNGALVGTLYGGSVTCTARNGSDYYGRFDVA
YSAALQQWLSPVTSSNGRTAVYRFFNGSTGAHFYTSSAGERDFVIATYPAFSYEGVGFYAYGGATAGQSAVFRLFNTSTG
AHFYTIDAGERDFVRATYPAFQYEGPAWYAQTAAGNGSTAMYRFFNKTTGAHFYTISQGERDFVIATYPVFQYEGPVYYA
WTN
>Mature_643_residues
MEFRLRSIRAVMVLGAAALLAACGGGGGPEAGSSASVAAAPRAAVLSVEAREQPAEAAQDTVRLKDLSVRPALAPARVTL
GALLESRSGAAEAAVGPRRIGAARAVEATATPAALAGRLQWTPTAAGGLVAAISFTAQDAHGLRLGVLVRALPGGAQLRV
YRQDRPSAVYEISGQEVLQTIDRNIAAGDASDAGRTWWTPDTGGDEATLEIELPPGTPASALDIAIPRLSHIYTNLSLPT
ADEGEQAKIGQSGSCNLDSSCYDAYASQRNAVARMVFVRPDGNAYLCTGTLLNDRDGTGTPYFISANHCFSSQTVASTLR
TDWFYRSPSCNSRTLSANATARTGGATLLYANSSTDTLFVRLNETPPAGAVFAAWNAGTQPLGSAAVGIHHPRGDLQKIS
FGSITSLSSCSALSDSSTSFSCSGTSGNYYRVGWTDGVTEGGSSGSGLFVNGALVGTLYGGSVTCTARNGSDYYGRFDVA
YSAALQQWLSPVTSSNGRTAVYRFFNGSTGAHFYTSSAGERDFVIATYPAFSYEGVGFYAYGGATAGQSAVFRLFNTSTG
AHFYTIDAGERDFVRATYPAFQYEGPAWYAQTAAGNGSTAMYRFFNKTTGAHFYTISQGERDFVIATYPVFQYEGPVYYA
WTN

Specific function: Lysine-specific endoprotease. Involved in corneal virulence [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Secreted [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase S1 family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009003 [H]

Pfam domain/function: NA

EC number: =3.4.21.50 [H]

Molecular weight: Translated: 67431; Mature: 67431

Theoretical pI: Translated: 6.51; Mature: 6.51

Prosite motif: PS00013 PROKAR_LIPOPROTEIN ; PS00019 ACTININ_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
0.6 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
0.6 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEFRLRSIRAVMVLGAAALLAACGGGGGPEAGSSASVAAAPRAAVLSVEAREQPAEAAQD
CCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEECCCCEEEEEEECCCCCHHHHHH
TVRLKDLSVRPALAPARVTLGALLESRSGAAEAAVGPRRIGAARAVEATATPAALAGRLQ
HEEEEECCCCCCCCCHHHHHHHHHHCCCCCCHHCCCCHHCCCHHEEECCCCCHHHHCCEE
WTPTAAGGLVAAISFTAQDAHGLRLGVLVRALPGGAQLRVYRQDRPSAVYEISGQEVLQT
ECCCCCCCEEEEEEEECCCCCCEEEEEEEEECCCCCEEEEEECCCCCEEEEECHHHHHHH
IDRNIAAGDASDAGRTWWTPDTGGDEATLEIELPPGTPASALDIAIPRLSHIYTNLSLPT
HHCCCCCCCCCCCCCEEECCCCCCCCEEEEEECCCCCCCCHHEEEHHHHHHHHCCCCCCC
ADEGEQAKIGQSGSCNLDSSCYDAYASQRNAVARMVFVRPDGNAYLCTGTLLNDRDGTGT
CCCCCCCCCCCCCCCCCCCHHHHHHHHCCCCEEEEEEECCCCCEEEEEEEEEECCCCCCC
PYFISANHCFSSQTVASTLRTDWFYRSPSCNSRTLSANATARTGGATLLYANSSTDTLFV
CEEEECCCCCCCHHHHHHHHHCEEEECCCCCCEEEECCCCCCCCCEEEEEECCCCCEEEE
RLNETPPAGAVFAAWNAGTQPLGSAAVGIHHPRGDLQKISFGSITSLSSCSALSDSSTSF
EECCCCCCCEEEEECCCCCCCCCCCEEEEECCCCCCEEECCCCCCCCCCCCCCCCCCCEE
SCSGTSGNYYRVGWTDGVTEGGSSGSGLFVNGALVGTLYGGSVTCTARNGSDYYGRFDVA
EEECCCCCEEEEECCCCCCCCCCCCCCEEEECEEEEEEECCEEEEEECCCCCCCEEEHHH
YSAALQQWLSPVTSSNGRTAVYRFFNGSTGAHFYTSSAGERDFVIATYPAFSYEGVGFYA
HHHHHHHHHHHHHCCCCCEEEEEEECCCCCCEEEECCCCCCEEEEEECCCCCCCCEEEEE
YGGATAGQSAVFRLFNTSTGAHFYTIDAGERDFVRATYPAFQYEGPAWYAQTAAGNGSTA
ECCCCCCCCCEEEEEECCCCCEEEEEECCCCCEEEEECCCEEECCCCEEEEECCCCCCEE
MYRFFNKTTGAHFYTISQGERDFVIATYPVFQYEGPVYYAWTN
EEEEECCCCCCEEEEECCCCCCEEEEEEEEEEECCCEEEEECC
>Mature Secondary Structure
MEFRLRSIRAVMVLGAAALLAACGGGGGPEAGSSASVAAAPRAAVLSVEAREQPAEAAQD
CCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEECCCCEEEEEEECCCCCHHHHHH
TVRLKDLSVRPALAPARVTLGALLESRSGAAEAAVGPRRIGAARAVEATATPAALAGRLQ
HEEEEECCCCCCCCCHHHHHHHHHHCCCCCCHHCCCCHHCCCHHEEECCCCCHHHHCCEE
WTPTAAGGLVAAISFTAQDAHGLRLGVLVRALPGGAQLRVYRQDRPSAVYEISGQEVLQT
ECCCCCCCEEEEEEEECCCCCCEEEEEEEEECCCCCEEEEEECCCCCEEEEECHHHHHHH
IDRNIAAGDASDAGRTWWTPDTGGDEATLEIELPPGTPASALDIAIPRLSHIYTNLSLPT
HHCCCCCCCCCCCCCEEECCCCCCCCEEEEEECCCCCCCCHHEEEHHHHHHHHCCCCCCC
ADEGEQAKIGQSGSCNLDSSCYDAYASQRNAVARMVFVRPDGNAYLCTGTLLNDRDGTGT
CCCCCCCCCCCCCCCCCCCHHHHHHHHCCCCEEEEEEECCCCCEEEEEEEEEECCCCCCC
PYFISANHCFSSQTVASTLRTDWFYRSPSCNSRTLSANATARTGGATLLYANSSTDTLFV
CEEEECCCCCCCHHHHHHHHHCEEEECCCCCCEEEECCCCCCCCCEEEEEECCCCCEEEE
RLNETPPAGAVFAAWNAGTQPLGSAAVGIHHPRGDLQKISFGSITSLSSCSALSDSSTSF
EECCCCCCCEEEEECCCCCCCCCCCEEEEECCCCCCEEECCCCCCCCCCCCCCCCCCCEE
SCSGTSGNYYRVGWTDGVTEGGSSGSGLFVNGALVGTLYGGSVTCTARNGSDYYGRFDVA
EEECCCCCEEEEECCCCCCCCCCCCCCEEEECEEEEEEECCEEEEEECCCCCCCEEEHHH
YSAALQQWLSPVTSSNGRTAVYRFFNGSTGAHFYTSSAGERDFVIATYPAFSYEGVGFYA
HHHHHHHHHHHHHCCCCCEEEEEEECCCCCCEEEECCCCCCEEEEEECCCCCCCCEEEEE
YGGATAGQSAVFRLFNTSTGAHFYTIDAGERDFVRATYPAFQYEGPAWYAQTAAGNGSTA
ECCCCCCCCCEEEEEECCCCCEEEEEECCCCCEEEEECCCEEECCCCEEEEECCCCCCEE
MYRFFNKTTGAHFYTISQGERDFVIATYPVFQYEGPVYYAWTN
EEEEECCCCCCEEEEECCCCCCEEEEEEEEEEECCCEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12419815; 10984043 [H]