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The map label for this gene is ruvB [H]

Identifier: 120612873

GI number: 120612873

Start: 4693663

End: 4694727

Strand: Reverse

Name: ruvB [H]

Synonym: Aave_4237

Alternate gene names: 120612873

Gene position: 4694727-4693663 (Counterclockwise)

Preceding gene: 120612874

Following gene: 120612872

Centisome position: 87.71

GC content: 71.17

Gene sequence:

>1065_bases
ATGAGCATCCAGACCGACGACTTCGCCCCCGTGCCCCCGCCCAAGCGGGTGGTCTCCGCCGCCCCCACCTCCCCGCAGGA
GGAGGCGCTGGAGCGCGCGCTGCGGCCCAAGCTGCTGCAGGAGTACGTCGGGCAGGCCAAGGCGCGCGAGCAGCTGGAGA
TCTTCATCGGGGCCGCGCGCAAGCGCGAGGAGGCGCTCGACCACGTGCTGCTGTTCGGCCCGCCGGGCCTGGGCAAGACC
ACGCTCAGCCACATCATCGCGGCGGAGCTGGGGGTGAACCTGCGCCAGACCAGCGGCCCGGTGCTGGAAAAGCCCAAGGA
CCTGGCGGCGCTGCTCACCAATCTCGAGAAGAACGACGTCCTCTTCATCGACGAGATCCACCGCCTCTCGCCCGTGGTCG
AGGAAATCCTCTACCCCGCGCTGGAGGACTACCAGATCGACATCATGATCGGCGAGGGGCCGGCGGCGCGCAGCATCAAG
CTCGACCTGCAGCCCTTCACGCTGGTCGGCGCCACCACCCGCGCCGGCATGCTCACCAACCCGCTGCGCGACCGCTTCGG
CATCGTCGCGCGGCTGGAGTTCTACACGCCCGAGGAGCTGTCGCGCATCGTGACGCGGTCCGCCGGGCTGCTGAACGCCC
CCATCGACGCCCAGGGCGCCTTCGAGATCGCGCGCCGCTCGCGCGGCACGCCGCGCATCGCCAACCGGCTGCTGCGCCGC
GTGCGCGACTATGCCGACGTCAAGGGCGACGGCCGCATCACGCAGGACATCGCCCAGCGCGCGCTCGCCATGCTGGACGT
GGACCCGCAGGGCTTCGATGTGATGGACCGCAAGCTCCTGGAGGCCGTGGTGCACCGCTTCGACGGCGGCCCGGTGGGAC
TGGACAACATCGCCGCGAGCATCGGCGAGGAGCCGGGCACCATCGAGGACGTGATCGAGCCCTACCTCATCCAGCAGGGC
TACCTGCAGCGCACGCCACGCGGCCGCATCGCCACCCTGGCGGCCTTCCGCCACCTGGGCGTGGCGCCCTCGCGCCAGCA
CACCGACCTGTTCGGGCCCGCCTGA

Upstream 100 bases:

>100_bases
ATCGCGACCTACCCGGTGTTCCAGTACGAAGGCCCGGTGTACTACGCCTGGACGAACTGACGGCCCGGCGGCGCCAGCTC
TCCTCACGTTTTCCGCATCC

Downstream 100 bases:

>100_bases
GCCAGCGGCGCATGGCGGTTTCCGCCTTCCATCCTGAGGCCGCCCCGGTCCTCCCGCAAGCATTCCGGAAACGGTGTTGC
CGCAAGGCGTCATTCGGGGA

Product: Holliday junction DNA helicase RuvB

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 354; Mature: 353

Protein sequence:

>354_residues
MSIQTDDFAPVPPPKRVVSAAPTSPQEEALERALRPKLLQEYVGQAKAREQLEIFIGAARKREEALDHVLLFGPPGLGKT
TLSHIIAAELGVNLRQTSGPVLEKPKDLAALLTNLEKNDVLFIDEIHRLSPVVEEILYPALEDYQIDIMIGEGPAARSIK
LDLQPFTLVGATTRAGMLTNPLRDRFGIVARLEFYTPEELSRIVTRSAGLLNAPIDAQGAFEIARRSRGTPRIANRLLRR
VRDYADVKGDGRITQDIAQRALAMLDVDPQGFDVMDRKLLEAVVHRFDGGPVGLDNIAASIGEEPGTIEDVIEPYLIQQG
YLQRTPRGRIATLAAFRHLGVAPSRQHTDLFGPA

Sequences:

>Translated_354_residues
MSIQTDDFAPVPPPKRVVSAAPTSPQEEALERALRPKLLQEYVGQAKAREQLEIFIGAARKREEALDHVLLFGPPGLGKT
TLSHIIAAELGVNLRQTSGPVLEKPKDLAALLTNLEKNDVLFIDEIHRLSPVVEEILYPALEDYQIDIMIGEGPAARSIK
LDLQPFTLVGATTRAGMLTNPLRDRFGIVARLEFYTPEELSRIVTRSAGLLNAPIDAQGAFEIARRSRGTPRIANRLLRR
VRDYADVKGDGRITQDIAQRALAMLDVDPQGFDVMDRKLLEAVVHRFDGGPVGLDNIAASIGEEPGTIEDVIEPYLIQQG
YLQRTPRGRIATLAAFRHLGVAPSRQHTDLFGPA
>Mature_353_residues
SIQTDDFAPVPPPKRVVSAAPTSPQEEALERALRPKLLQEYVGQAKAREQLEIFIGAARKREEALDHVLLFGPPGLGKTT
LSHIIAAELGVNLRQTSGPVLEKPKDLAALLTNLEKNDVLFIDEIHRLSPVVEEILYPALEDYQIDIMIGEGPAARSIKL
DLQPFTLVGATTRAGMLTNPLRDRFGIVARLEFYTPEELSRIVTRSAGLLNAPIDAQGAFEIARRSRGTPRIANRLLRRV
RDYADVKGDGRITQDIAQRALAMLDVDPQGFDVMDRKLLEAVVHRFDGGPVGLDNIAASIGEEPGTIEDVIEPYLIQQGY
LQRTPRGRIATLAAFRHLGVAPSRQHTDLFGPA

Specific function: The ruvA-ruvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is an helicase that mediates the Holliday

COG id: COG2255

COG function: function code L; Holliday junction resolvasome, helicase subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ruvB family [H]

Homologues:

Organism=Escherichia coli, GI1788167, Length=328, Percent_Identity=70.7317073170732, Blast_Score=466, Evalue=1e-133,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR004605
- InterPro:   IPR008823
- InterPro:   IPR008824
- InterPro:   IPR011991
- ProDom:   PD005323 [H]

Pfam domain/function: PF05491 RuvB_C; PF05496 RuvB_N [H]

EC number: =3.6.4.12 [H]

Molecular weight: Translated: 38931; Mature: 38800

Theoretical pI: Translated: 6.01; Mature: 6.01

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
1.4 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
1.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSIQTDDFAPVPPPKRVVSAAPTSPQEEALERALRPKLLQEYVGQAKAREQLEIFIGAAR
CCCCCCCCCCCCCHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KREEALDHVLLFGPPGLGKTTLSHIIAAELGVNLRQTSGPVLEKPKDLAALLTNLEKNDV
HHHHHHCEEEEECCCCCCHHHHHHHHHHHHCCCEECCCCCCCCCHHHHHHHHHCCCCCCE
LFIDEIHRLSPVVEEILYPALEDYQIDIMIGEGPAARSIKLDLQPFTLVGATTRAGMLTN
EEHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCCCEEEEECCCEEEECCCHHCCHHHH
PLRDRFGIVARLEFYTPEELSRIVTRSAGLLNAPIDAQGAFEIARRSRGTPRIANRLLRR
HHHHHHCEEEEEECCCHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHCCCCHHHHHHHHHH
VRDYADVKGDGRITQDIAQRALAMLDVDPQGFDVMDRKLLEAVVHRFDGGPVGLDNIAAS
HHHHHCCCCCCCHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCCCCCCHHHHHHH
IGEEPGTIEDVIEPYLIQQGYLQRTPRGRIATLAAFRHLGVAPSRQHTDLFGPA
HCCCCCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCC
>Mature Secondary Structure 
SIQTDDFAPVPPPKRVVSAAPTSPQEEALERALRPKLLQEYVGQAKAREQLEIFIGAAR
CCCCCCCCCCCCHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KREEALDHVLLFGPPGLGKTTLSHIIAAELGVNLRQTSGPVLEKPKDLAALLTNLEKNDV
HHHHHHCEEEEECCCCCCHHHHHHHHHHHHCCCEECCCCCCCCCHHHHHHHHHCCCCCCE
LFIDEIHRLSPVVEEILYPALEDYQIDIMIGEGPAARSIKLDLQPFTLVGATTRAGMLTN
EEHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCCCEEEEECCCEEEECCCHHCCHHHH
PLRDRFGIVARLEFYTPEELSRIVTRSAGLLNAPIDAQGAFEIARRSRGTPRIANRLLRR
HHHHHHCEEEEEECCCHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHCCCCHHHHHHHHHH
VRDYADVKGDGRITQDIAQRALAMLDVDPQGFDVMDRKLLEAVVHRFDGGPVGLDNIAAS
HHHHHCCCCCCCHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCCCCCCHHHHHHH
IGEEPGTIEDVIEPYLIQQGYLQRTPRGRIATLAAFRHLGVAPSRQHTDLFGPA
HCCCCCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA