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The map label for this gene is marC [H]

Identifier: 120612525

GI number: 120612525

Start: 4309407

End: 4310108

Strand: Reverse

Name: marC [H]

Synonym: Aave_3885

Alternate gene names: 120612525

Gene position: 4310108-4309407 (Counterclockwise)

Preceding gene: 120612526

Following gene: 120612524

Centisome position: 80.52

GC content: 66.67

Gene sequence:

>702_bases
GTGACACTTGAACTTCTGGGCGCCTTCGGCAAGAGCTTTCTCTTCGTGATTGCCGCGCTGCTGCCTATCGTGAATCCGGC
CGCCACGGCGCCCATCTTCCTGGGCCTGACCGAGGGGGCATCACCGACCACGCGCGCACTGCTGGCGCGCCGCATCGCAC
GCAACATGTTCTGGCTGCTGCTGGGCGCCATGCTGGTCGGCTCCTACGTGCTGGAGTTCTTCGGCATCTCGCTGCCCATC
GTGCGCGTGGGTGGCGGCATGATCGTGGCAGCGACGGCCTGGCGGTTGCTGACGGCCACGCAGGCCACGGTGGACAGCCG
CACCGAACTGGCCGAGAGCTTCACGCCCGACATGGCGCGACGCCAGGCTTTCTACCCGCTCACCTTTCCGGTGAGTTGCG
GGCCCGGCTCGATCGCGGCGGCCATCACGGTGGGGGTGTCGCTGGCCGACGCGCGGCTGTCGATGTCGCTGGCGCGGATG
GGAGGTGGCGTACTGGCGCTGCTGTCCGTCGCCGTACTGCTGTACTTCGCCTTCCGCTATGCGCAGCAATTGCTCAAGCC
GCTCGGCGAAGCCGGCTCGGTGATCTTCCTGCGGTTGTCGGCCTTCATCCTGCTGTGCCTGGGCGTGCAGATCGTGTGGG
ACGGCGTGTACGAACTGGGCGTCGCGATGTTGCGCGACGGGATGCTGCCACTGAATTCTTGA

Upstream 100 bases:

>100_bases
TGCGCAAAGATCACCAAGAAGAGCAGTTCCGCGAGCGAGCGCTAAGCCGGCGCATGAGGGAGTTCGTCGACCAGACGCTC
CCCATCTGAATAGGGACACC

Downstream 100 bases:

>100_bases
ACTTCGACTTCAGTTCATGGCCTGCTGCTTCGCTCGCCTAACGGTTGGATCTCCCCGGCTGCCGGGCCGCGGCAAGATCG
ATCTTCGCAGCGCAGACATC

Product: multiple antibiotic resistance (MarC)-like protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 233; Mature: 232

Protein sequence:

>233_residues
MTLELLGAFGKSFLFVIAALLPIVNPAATAPIFLGLTEGASPTTRALLARRIARNMFWLLLGAMLVGSYVLEFFGISLPI
VRVGGGMIVAATAWRLLTATQATVDSRTELAESFTPDMARRQAFYPLTFPVSCGPGSIAAAITVGVSLADARLSMSLARM
GGGVLALLSVAVLLYFAFRYAQQLLKPLGEAGSVIFLRLSAFILLCLGVQIVWDGVYELGVAMLRDGMLPLNS

Sequences:

>Translated_233_residues
MTLELLGAFGKSFLFVIAALLPIVNPAATAPIFLGLTEGASPTTRALLARRIARNMFWLLLGAMLVGSYVLEFFGISLPI
VRVGGGMIVAATAWRLLTATQATVDSRTELAESFTPDMARRQAFYPLTFPVSCGPGSIAAAITVGVSLADARLSMSLARM
GGGVLALLSVAVLLYFAFRYAQQLLKPLGEAGSVIFLRLSAFILLCLGVQIVWDGVYELGVAMLRDGMLPLNS
>Mature_232_residues
TLELLGAFGKSFLFVIAALLPIVNPAATAPIFLGLTEGASPTTRALLARRIARNMFWLLLGAMLVGSYVLEFFGISLPIV
RVGGGMIVAATAWRLLTATQATVDSRTELAESFTPDMARRQAFYPLTFPVSCGPGSIAAAITVGVSLADARLSMSLARMG
GGVLALLSVAVLLYFAFRYAQQLLKPLGEAGSVIFLRLSAFILLCLGVQIVWDGVYELGVAMLRDGMLPLNS

Specific function: Unknown

COG id: COG2095

COG function: function code U; Multiple antibiotic transporter

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the UPF0056 (marC) family [H]

Homologues:

Organism=Escherichia coli, GI1787809, Length=197, Percent_Identity=29.9492385786802, Blast_Score=93, Evalue=2e-20,
Organism=Escherichia coli, GI1787494, Length=202, Percent_Identity=24.7524752475248, Blast_Score=63, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002771 [H]

Pfam domain/function: PF01914 MarC [H]

EC number: NA

Molecular weight: Translated: 24732; Mature: 24601

Theoretical pI: Translated: 9.57; Mature: 9.57

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTLELLGAFGKSFLFVIAALLPIVNPAATAPIFLGLTEGASPTTRALLARRIARNMFWLL
CCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHH
LGAMLVGSYVLEFFGISLPIVRVGGGMIVAATAWRLLTATQATVDSRTELAESFTPDMAR
HHHHHHHHHHHHHHCCCCHHEEECCCEEHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHH
RQAFYPLTFPVSCGPGSIAAAITVGVSLADARLSMSLARMGGGVLALLSVAVLLYFAFRY
HCCCCCEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHH
AQQLLKPLGEAGSVIFLRLSAFILLCLGVQIVWDGVYELGVAMLRDGMLPLNS
HHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
>Mature Secondary Structure 
TLELLGAFGKSFLFVIAALLPIVNPAATAPIFLGLTEGASPTTRALLARRIARNMFWLL
CHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHH
LGAMLVGSYVLEFFGISLPIVRVGGGMIVAATAWRLLTATQATVDSRTELAESFTPDMAR
HHHHHHHHHHHHHHCCCCHHEEECCCEEHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHH
RQAFYPLTFPVSCGPGSIAAAITVGVSLADARLSMSLARMGGGVLALLSVAVLLYFAFRY
HCCCCCEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHH
AQQLLKPLGEAGSVIFLRLSAFILLCLGVQIVWDGVYELGVAMLRDGMLPLNS
HHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA