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The map label for this gene is pqqL [C]

Identifier: 120612513

GI number: 120612513

Start: 4296292

End: 4297746

Strand: Reverse

Name: pqqL [C]

Synonym: Aave_3872

Alternate gene names: 120612513

Gene position: 4297746-4296292 (Counterclockwise)

Preceding gene: 120612514

Following gene: 120612512

Centisome position: 80.29

GC content: 71.48

Gene sequence:

>1455_bases
ATGAAACGCGCACTCACCCTCCTGGGCCTGCTGGCCTGCGTGCATGCCGGGGCCCAGCCCCCCGCTGTCGCCACGTCCTA
TCCCTCGCCTGCGTCGGCGCAAGGCTCCCAGCCCGGGGCCCGGGCGCCCGGCGTGCATCAATACACGCTGCGCAACGGCA
TGCAGCTGTTCGTGCAGACCGACCGGCGCGCGCCCACCGCAGTGCACATGGTGTGGGTGCGGGTCGGCTCGATGGACGAG
GTGGACGGCACATCGGGCGTGGCCCACGCCCTGGAGCACATGATGTTCAAGGGCACGAAGACGGTGCCGCCAGGACAGTT
CTCGCGCCGCATCGCCGCGTTGGGCGGACAGGAAAACGCGTTCACCAACCGCGACTACACGGGCTACTACCAGCAGATTC
CCGCGAAGCGCCTCGCGGAAGTCATGCGCCTGGAAGCCGACCGGTTCGCGCACAACCAATGGCCGGACGCGGAGTTCAGC
AAGGAGATCGAGGTCATCAAGGAGGAGCGGCGCATGCGCACGGACGATCAGCCGCGCGCGGCCCTGATGGAGCAGCTCAA
CGCCGCCGTGTTCACGGCGTCTCCCTACCGGCGGCCGGTGGTCGGCTGGATGAGCGACCTGGATGCGATGACGCCGGACG
ATGTCCGCGCGTTCCACCGCCAGTGGTACGTGCCCGCGAACGCCGCCATCGTGGTGGCCGGCGACGTGGACCCGGAAGCC
GTCCGCAAGCTCGCCGAGGACACCTACGGCCGCATTCCCGCAGCGGCGGTACCGGTGCGCAAGCCGCGCACCGAGCCGGC
CCAGCGCGGCCTGCGCCGCATCGATTTCAAGGCGCCCGCGGAACAGGCCTTCGTCGCGATGGCGTTCCGGGTGCCCGGGC
TGCAGCGGCTGGAGCAGCTCACGGATTCCGACCGCGATGCGCTGGCGTTGATGATGCTTTCGGGCGTGCTCAGCGGCTAC
GACGGCGCACGGCTGGAGCGCTCTCTCACGCAGGGGGCCGACCGCGTGGCCGACGGAGCGGACAGCGGTGCCTCCGTCAT
GGGCCGGGGGCCGAGCCTGTTCCTGTTGAGCGGCGTCCCCGCGGGTGGCAAGACGGCGCAGCAGGTCGAGGCCGCGCTGC
GGGCCGAGGTGGCCCGCGTGGCGCGCGAAGGGGTGGGCGATGCCGAACTCTCGCGCGTGAAGACCCAGTGGGCGGCATCC
ACCATCTATGCACGCGATTCGCTGCAGGCGCAGGCGAGCGACCTGGGCAGCAACTGGGTGCAGGGCCTGCCGCCCGACGC
CGACGCGCGGCTGCTGGCGCTGCTGCGCGAGGTGACGCCGGCGCAGGTCCAGGCCGTGGCCGGCCGCTATTTCGGCGATG
ACCAGTTGACCGTGGCCACCCTGGTGCCACAGCCGGTGGCCCCCGGTTCCCGCCGTCCCGCCGCTCCCGCGAGCGCCGAC
GGACGCATGCACTGA

Upstream 100 bases:

>100_bases
TCGGCCGGTGCCGGTGGCGGGGTCTCCGCAGCGGGAGCAGGAGCTGGCTTTTTCTTGAAAAAACTGAACATTGGCAGGTT
CTTAGAATCGCACCCATTCT

Downstream 100 bases:

>100_bases
CGCGCCGCCGGTCGGAAGGAATTTCCCATGATGCCCCTTGCAATCAAAAAAGCCGCCCTCCGCGCGGCATTCGCCGCGGC
GGCAGGCCTGCTGGCCGCGC

Product: peptidase M16 domain-containing protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 484; Mature: 484

Protein sequence:

>484_residues
MKRALTLLGLLACVHAGAQPPAVATSYPSPASAQGSQPGARAPGVHQYTLRNGMQLFVQTDRRAPTAVHMVWVRVGSMDE
VDGTSGVAHALEHMMFKGTKTVPPGQFSRRIAALGGQENAFTNRDYTGYYQQIPAKRLAEVMRLEADRFAHNQWPDAEFS
KEIEVIKEERRMRTDDQPRAALMEQLNAAVFTASPYRRPVVGWMSDLDAMTPDDVRAFHRQWYVPANAAIVVAGDVDPEA
VRKLAEDTYGRIPAAAVPVRKPRTEPAQRGLRRIDFKAPAEQAFVAMAFRVPGLQRLEQLTDSDRDALALMMLSGVLSGY
DGARLERSLTQGADRVADGADSGASVMGRGPSLFLLSGVPAGGKTAQQVEAALRAEVARVAREGVGDAELSRVKTQWAAS
TIYARDSLQAQASDLGSNWVQGLPPDADARLLALLREVTPAQVQAVAGRYFGDDQLTVATLVPQPVAPGSRRPAAPASAD
GRMH

Sequences:

>Translated_484_residues
MKRALTLLGLLACVHAGAQPPAVATSYPSPASAQGSQPGARAPGVHQYTLRNGMQLFVQTDRRAPTAVHMVWVRVGSMDE
VDGTSGVAHALEHMMFKGTKTVPPGQFSRRIAALGGQENAFTNRDYTGYYQQIPAKRLAEVMRLEADRFAHNQWPDAEFS
KEIEVIKEERRMRTDDQPRAALMEQLNAAVFTASPYRRPVVGWMSDLDAMTPDDVRAFHRQWYVPANAAIVVAGDVDPEA
VRKLAEDTYGRIPAAAVPVRKPRTEPAQRGLRRIDFKAPAEQAFVAMAFRVPGLQRLEQLTDSDRDALALMMLSGVLSGY
DGARLERSLTQGADRVADGADSGASVMGRGPSLFLLSGVPAGGKTAQQVEAALRAEVARVAREGVGDAELSRVKTQWAAS
TIYARDSLQAQASDLGSNWVQGLPPDADARLLALLREVTPAQVQAVAGRYFGDDQLTVATLVPQPVAPGSRRPAAPASAD
GRMH
>Mature_484_residues
MKRALTLLGLLACVHAGAQPPAVATSYPSPASAQGSQPGARAPGVHQYTLRNGMQLFVQTDRRAPTAVHMVWVRVGSMDE
VDGTSGVAHALEHMMFKGTKTVPPGQFSRRIAALGGQENAFTNRDYTGYYQQIPAKRLAEVMRLEADRFAHNQWPDAEFS
KEIEVIKEERRMRTDDQPRAALMEQLNAAVFTASPYRRPVVGWMSDLDAMTPDDVRAFHRQWYVPANAAIVVAGDVDPEA
VRKLAEDTYGRIPAAAVPVRKPRTEPAQRGLRRIDFKAPAEQAFVAMAFRVPGLQRLEQLTDSDRDALALMMLSGVLSGY
DGARLERSLTQGADRVADGADSGASVMGRGPSLFLLSGVPAGGKTAQQVEAALRAEVARVAREGVGDAELSRVKTQWAAS
TIYARDSLQAQASDLGSNWVQGLPPDADARLLALLREVTPAQVQAVAGRYFGDDQLTVATLVPQPVAPGSRRPAAPASAD
GRMH

Specific function: Unknown

COG id: COG0612

COG function: function code R; Predicted Zn-dependent peptidases

Gene ontology:

Cell location: Cell membrane; Single-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M16 family [H]

Homologues:

Organism=Homo sapiens, GI46593007, Length=293, Percent_Identity=26.962457337884, Blast_Score=96, Evalue=6e-20,
Organism=Homo sapiens, GI94538354, Length=216, Percent_Identity=25.462962962963, Blast_Score=74, Evalue=2e-13,
Organism=Escherichia coli, GI1787770, Length=364, Percent_Identity=26.3736263736264, Blast_Score=103, Evalue=2e-23,
Organism=Caenorhabditis elegans, GI17553678, Length=287, Percent_Identity=26.1324041811847, Blast_Score=80, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI71999683, Length=282, Percent_Identity=23.758865248227, Blast_Score=77, Evalue=2e-14,
Organism=Saccharomyces cerevisiae, GI6323192, Length=398, Percent_Identity=22.1105527638191, Blast_Score=82, Evalue=2e-16,
Organism=Drosophila melanogaster, GI21357875, Length=341, Percent_Identity=24.3401759530792, Blast_Score=94, Evalue=2e-19,
Organism=Drosophila melanogaster, GI24646943, Length=341, Percent_Identity=24.3401759530792, Blast_Score=94, Evalue=2e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011249
- InterPro:   IPR011237
- InterPro:   IPR011765
- InterPro:   IPR001431
- InterPro:   IPR007863 [H]

Pfam domain/function: PF00675 Peptidase_M16; PF05193 Peptidase_M16_C [H]

EC number: 3.4.99.- [C]

Molecular weight: Translated: 52264; Mature: 52264

Theoretical pI: Translated: 9.16; Mature: 9.16

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKRALTLLGLLACVHAGAQPPAVATSYPSPASAQGSQPGARAPGVHQYTLRNGMQLFVQT
CCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHCCCEEEEEC
DRRAPTAVHMVWVRVGSMDEVDGTSGVAHALEHMMFKGTKTVPPGQFSRRIAALGGQENA
CCCCCHHEEEEEHEECCCCCCCCCHHHHHHHHHHHHCCCCCCCCCHHHHHHHHCCCCCCC
FTNRDYTGYYQQIPAKRLAEVMRLEADRFAHNQWPDAEFSKEIEVIKEERRMRTDDQPRA
CCCCCCCCHHHHCCHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCCCCHHH
ALMEQLNAAVFTASPYRRPVVGWMSDLDAMTPDDVRAFHRQWYVPANAAIVVAGDVDPEA
HHHHHHHHHEEECCCCCCHHHHHHHHHCCCCHHHHHHHHHHCCCCCCCEEEEECCCCHHH
VRKLAEDTYGRIPAAAVPVRKPRTEPAQRGLRRIDFKAPAEQAFVAMAFRVPGLQRLEQL
HHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHCCCCCCHHHHHHHHHHHCCCHHHHHHH
TDSDRDALALMMLSGVLSGYDGARLERSLTQGADRVADGADSGASVMGRGPSLFLLSGVP
HCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCCCCHHHCCCCCEEEEECCC
AGGKTAQQVEAALRAEVARVAREGVGDAELSRVKTQWAASTIYARDSLQAQASDLGSNWV
CCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QGLPPDADARLLALLREVTPAQVQAVAGRYFGDDQLTVATLVPQPVAPGSRRPAAPASAD
CCCCCCCHHHHHHHHHHCCHHHHHHHHHHHCCCCCEEEEEECCCCCCCCCCCCCCCCCCC
GRMH
CCCC
>Mature Secondary Structure
MKRALTLLGLLACVHAGAQPPAVATSYPSPASAQGSQPGARAPGVHQYTLRNGMQLFVQT
CCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHCCCEEEEEC
DRRAPTAVHMVWVRVGSMDEVDGTSGVAHALEHMMFKGTKTVPPGQFSRRIAALGGQENA
CCCCCHHEEEEEHEECCCCCCCCCHHHHHHHHHHHHCCCCCCCCCHHHHHHHHCCCCCCC
FTNRDYTGYYQQIPAKRLAEVMRLEADRFAHNQWPDAEFSKEIEVIKEERRMRTDDQPRA
CCCCCCCCHHHHCCHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCCCCHHH
ALMEQLNAAVFTASPYRRPVVGWMSDLDAMTPDDVRAFHRQWYVPANAAIVVAGDVDPEA
HHHHHHHHHEEECCCCCCHHHHHHHHHCCCCHHHHHHHHHHCCCCCCCEEEEECCCCHHH
VRKLAEDTYGRIPAAAVPVRKPRTEPAQRGLRRIDFKAPAEQAFVAMAFRVPGLQRLEQL
HHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHCCCCCCHHHHHHHHHHHCCCHHHHHHH
TDSDRDALALMMLSGVLSGYDGARLERSLTQGADRVADGADSGASVMGRGPSLFLLSGVP
HCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCCCCHHHCCCCCEEEEECCC
AGGKTAQQVEAALRAEVARVAREGVGDAELSRVKTQWAASTIYARDSLQAQASDLGSNWV
CCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QGLPPDADARLLALLREVTPAQVQAVAGRYFGDDQLTVATLVPQPVAPGSRRPAAPASAD
CCCCCCCHHHHHHHHHHCCHHHHHHHHHHHCCCCCEEEEEECCCCCCCCCCCCCCCCCCC
GRMH
CCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: Zn [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Hydrolase; Acting on peptide bonds (Peptidases); Endopeptidases of unknown catalytic mechanism [C]

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9163424 [H]