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The map label for this gene is radC [C]

Identifier: 120612416

GI number: 120612416

Start: 4193282

End: 4193995

Strand: Direct

Name: radC [C]

Synonym: Aave_3773

Alternate gene names: 120612416

Gene position: 4193282-4193995 (Clockwise)

Preceding gene: 120612412

Following gene: 120612417

Centisome position: 78.34

GC content: 71.15

Gene sequence:

>714_bases
ATGGCTCTCAAGACTCTGCCCATCGAAGCCCGCCCCCGCGAACGACTGCTGGCGCGCGGCCCCTCCTCCCTCTCCGATAC
CGAACTCCTGGCCATCCTCCTGCGCACGGGCATCGTGGGCAAGGGCGTGATGCAGATGGCGCAGGAACTGCTCTCGCCCG
CGCTGCCCGACCCGGCCACCGGCGCGCTGCGCGGCGGGTTCGGCGGCATCGGCGGCCTGCTGCAGGCCGATGCCGACGCC
CTCAAGCGCATCAAGGGACTGGGCCCGGCCAAGCGCACGTCGCTCGTGGCCGTGCTGGAGCTGGCGCGCCGCATGCTGGC
GCAGACGCTGCCCAAGCGCGACCTGTTCCACTCGCCGCGCGCCGTGCGCGACTACCTGCAGCTGCACCTGGGCGGCAAGC
CGCACGAGGTGTTCTCGGTGCTCTTCCTGGACAGCCAGAACGGCCTCATCGCCATGGAGGAGATGTTCCGCGGCACGCTG
TCCCAGGCCAGCGTCTATCCGCGCGAGGTGGTGGTGCGCGCGCTGCACCACCATGCCGCCGCCGTGGTGCTGGTGCACAA
CCACCCCAGCGGCCAGGTGCAGCCGAGCCGCGCGGACGAAACCCTGACGCGCTCGCTGACCGACGCGCTGCGGCTCGTGG
ACGTCCGGGTGCTGGACCACATCATCGTCGCGCCGGGCTCCTCGCTGTCCATGGCGGAAGAAGGCCTGATCTGA

Upstream 100 bases:

>100_bases
CGCCTGTCAGCTTGCGGATGGTGTATAAAAACCCAGTATCCATGCCGCCCATCCGCGGTCACGGTGTCTGCCCCGATTGT
CCTTCCTTCTGTGCAACCCC

Downstream 100 bases:

>100_bases
CATCCGCGGACCGCTCCCCGGCCCGGCTGGCCGCCGCGCTGGCTCTCGGCGCCATGCTCGCTGCGTGCGCGCCGACGCCT
CCCGCGCCGCCGCCGCGGCT

Product: DNA repair protein RadC

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 237; Mature: 236

Protein sequence:

>237_residues
MALKTLPIEARPRERLLARGPSSLSDTELLAILLRTGIVGKGVMQMAQELLSPALPDPATGALRGGFGGIGGLLQADADA
LKRIKGLGPAKRTSLVAVLELARRMLAQTLPKRDLFHSPRAVRDYLQLHLGGKPHEVFSVLFLDSQNGLIAMEEMFRGTL
SQASVYPREVVVRALHHHAAAVVLVHNHPSGQVQPSRADETLTRSLTDALRLVDVRVLDHIIVAPGSSLSMAEEGLI

Sequences:

>Translated_237_residues
MALKTLPIEARPRERLLARGPSSLSDTELLAILLRTGIVGKGVMQMAQELLSPALPDPATGALRGGFGGIGGLLQADADA
LKRIKGLGPAKRTSLVAVLELARRMLAQTLPKRDLFHSPRAVRDYLQLHLGGKPHEVFSVLFLDSQNGLIAMEEMFRGTL
SQASVYPREVVVRALHHHAAAVVLVHNHPSGQVQPSRADETLTRSLTDALRLVDVRVLDHIIVAPGSSLSMAEEGLI
>Mature_236_residues
ALKTLPIEARPRERLLARGPSSLSDTELLAILLRTGIVGKGVMQMAQELLSPALPDPATGALRGGFGGIGGLLQADADAL
KRIKGLGPAKRTSLVAVLELARRMLAQTLPKRDLFHSPRAVRDYLQLHLGGKPHEVFSVLFLDSQNGLIAMEEMFRGTLS
QASVYPREVVVRALHHHAAAVVLVHNHPSGQVQPSRADETLTRSLTDALRLVDVRVLDHIIVAPGSSLSMAEEGLI

Specific function: Involved In DNA Repair. [C]

COG id: COG2003

COG function: function code L; DNA repair proteins

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the UPF0758 family

Homologues:

Organism=Escherichia coli, GI87082300, Length=226, Percent_Identity=39.3805309734513, Blast_Score=176, Evalue=2e-45,
Organism=Escherichia coli, GI2367100, Length=122, Percent_Identity=54.9180327868852, Blast_Score=135, Evalue=2e-33,
Organism=Escherichia coli, GI1788312, Length=122, Percent_Identity=54.0983606557377, Blast_Score=133, Evalue=8e-33,
Organism=Escherichia coli, GI1788997, Length=122, Percent_Identity=52.4590163934426, Blast_Score=130, Evalue=1e-31,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): Y3773_ACIAC (A1TTN2)

Other databases:

- EMBL:   CP000512
- RefSeq:   YP_972094.1
- ProteinModelPortal:   A1TTN2
- SMR:   A1TTN2
- STRING:   A1TTN2
- GeneID:   4667831
- GenomeReviews:   CP000512_GR
- KEGG:   aav:Aave_3773
- NMPDR:   fig|397945.5.peg.3224
- eggNOG:   COG2003
- HOGENOM:   HBG751042
- OMA:   HAAMAHE
- PhylomeDB:   A1TTN2
- BioCyc:   AAVE397945:AAVE_3773-MONOMER
- InterPro:   IPR010994
- InterPro:   IPR001405
- InterPro:   IPR020891
- TIGRFAMs:   TIGR00608

Pfam domain/function: PF04002 DUF2466; SSF47781 RuvA_2_like

EC number: NA

Molecular weight: Translated: 25519; Mature: 25388

Theoretical pI: Translated: 10.30; Mature: 10.30

Prosite motif: PS01302 UPF0758

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MALKTLPIEARPRERLLARGPSSLSDTELLAILLRTGIVGKGVMQMAQELLSPALPDPAT
CCCCCCCCCCCCHHHHHHCCCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCCCC
GALRGGFGGIGGLLQADADALKRIKGLGPAKRTSLVAVLELARRMLAQTLPKRDLFHSPR
CHHCCCCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCHHHHHCCCH
AVRDYLQLHLGGKPHEVFSVLFLDSQNGLIAMEEMFRGTLSQASVYPREVVVRALHHHAA
HHHHHHHHHCCCCHHHHEEEEEEECCCCEEHHHHHHHHHHHHHHCCHHHHHHHHHHHHHE
AVVLVHNHPSGQVQPSRADETLTRSLTDALRLVDVRVLDHIIVAPGSSLSMAEEGLI
EEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHCCCC
>Mature Secondary Structure 
ALKTLPIEARPRERLLARGPSSLSDTELLAILLRTGIVGKGVMQMAQELLSPALPDPAT
CCCCCCCCCCCHHHHHHCCCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCCCC
GALRGGFGGIGGLLQADADALKRIKGLGPAKRTSLVAVLELARRMLAQTLPKRDLFHSPR
CHHCCCCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCHHHHHCCCH
AVRDYLQLHLGGKPHEVFSVLFLDSQNGLIAMEEMFRGTLSQASVYPREVVVRALHHHAA
HHHHHHHHHCCCCHHHHEEEEEEECCCCEEHHHHHHHHHHHHHHCCHHHHHHHHHHHHHE
AVVLVHNHPSGQVQPSRADETLTRSLTDALRLVDVRVLDHIIVAPGSSLSMAEEGLI
EEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA