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The map label for this gene is tycC [H]

Identifier: 120612374

GI number: 120612374

Start: 4130352

End: 4133744

Strand: Reverse

Name: tycC [H]

Synonym: Aave_3731

Alternate gene names: 120612374

Gene position: 4133744-4130352 (Counterclockwise)

Preceding gene: 120612375

Following gene: 120612373

Centisome position: 77.23

GC content: 75.04

Gene sequence:

>3393_bases
ATGAGCGACAGTCCTCTTCTTTCCGAGCGCCGCGCGCGCCTTTCTCCCGAACAGCAGGCGCTGCTGCGGCAGCGGCTGGG
CGGCCGTCCCGCCGATGCGTCCGCTGCCGGCGGGGCGGAGCCGCCGCCTGCGTCCGCCGTGGATGCGCTGCCGCGCAGCG
GCGTGCCGGAGGGGGCCGAGGCCCCCCTGTCCTGGGCCCAGCAGGGCCAGTGGTTCCTCTGGCGCATGGACCCCGGCAAT
ACGGCCTACCACGTGGGGGGCGGGCTGGATTTCGAAGGCCCGCTGGACGCCGCGGCCCTGCATGCGGCGCTGCAGACCCT
GGTGCGGCGCCACGAGGGCCTGCGCACCGTCTTCGGCGAAGGCGGGGACGGCATGCCCTGGCAGCGCGTGGAACCCGCGC
GGGAGGTGCCACTGCCCTGCACCGATCTTTCAGGGCTGGCGCCGGCCGGGCGCGATGCCCGGCTGGAGGCACTGGCGCGC
GAGGTGTGCGCGCAGCCCTTCGACCTGCGCCGCGGCCCGCTGCTGCGCTGCGCGCTCGCCCGGCTGGGCCCGCGGGAACA
CCGGCTGCTGTTCATGATGCACCACATCGCCTCCGATGCCTGGACGGTGGAACGCATCCTCGACGAATGGGCGCGGGGCT
ACGCGGATGCGCTGGAGGGCCGCGCGCCGCCCGATGCGCCCCCGGCGCTGCGCTACGTGGATTTCGCGATCTGGCAGCGG
CAATGGCTGCAGGGGCCGGAGGCCGCACGGCACCGGGATTACTGGACACGGCAGCTCGCGGAGGAAGCGCCCGTGCTGCA
GATCGGCCGGGGCACCGCGGCCCCGTCGCCGCAGGCGCCCGAGGCACGCGACGCCGGGGCCGCGCAGCACCTGCTGGCCG
TGCCCGCCCCGCTGGCGCGGGCGCTGCGCCAGCGTGCCCGCGCGCACGGCACGACGCTGTTCTGCGTGCTGCTGGCGGGC
TTCCATGCGGTGCTGTTCCGCCATGCCGGGCACGCCGTGCAGCGCGTGGGCGTGCCCGTGGCGGGACGCAACCGCCCGGA
GACGGCCGACGTGGCCGGCGTCTTCATCAACACCGTGGTGATGCAGGCGCGGCCCGCGCCGCAGATGCCGCTCTCCGCCT
TGCTGGCGCAGGTGCATGCGACCGCGCTGGAGGCCCGTGAGCACGAGGACCTGCCGTTCGAGCACGTCGCGCAGGTGCTG
CGGCCCGAGCGCACACAGGAAGGCGGCGGACTGTTCCAGTGCATGTTCAACCACCTGGGCGAGGGCGGCCGGCCCCTGGC
GGGCTGGCCGGGGCTGGCGGTGCGCCGCGTCGATCCCGGGCTGCGCGCGGCGCCGTTCGGGCTCACGCTGGAAACCATGG
AAGACCCCGGGGGCGGGCTGCTCGCCGCTTTCCGCTACGACGGGGCGAAGTTCACACCGCAGGAGATGGCGGAGATCGCC
GGCCACTACGAACGCATGCTGGATGCGCTGGCCCACGATCCCGGTCGGCCCGTCGGCGAGGTCGCCATGCTCGGCGATGC
AGAGCGCGCGCGCCTGCAGGCATGGTCGGCGGGCGGGGAGGCCGCGGACCTGGACCTGCCCGTGCACCAGATGTTCGAGC
GCCAGGCGGCGCTCACGCCCGATGCGCCCGCCCTGGTGGCCGAAGGCCGCGAGTGGACGTATGCGCAGCTCGACGCGCGC
ACCAGCCGCCTCGCGCACCGGCTGCGCGCCTGCGGCGTGGGCCCGGAGATGCTGGTGGGCGTGGCGCTCGCCCGCGGTTC
GGACATGGTGGAGGCGCTGCTCGCGGTGCTGAAGGCCGGCGGCGCCTACGTGCCGCTCGACCCCGAGCTGCCGGCGGACC
GCATCGCCTACATGCTCGGCGACTGCGCCCCGGCACTGGTGCTGACCGATGCCGCCCACCGCGCCTGCCTGCCGGCGGCG
ATGGCACAACCCGTGGTCCTGCTGCCCCTGGAAGATGCACCGCCGGGCGATGGCGCGGAAGCCGCGTGCCTGCCCGTGGC
ACTGCATGCCGAGCACCTGGCCTACGTGATCTATACCTCCGGCTCCACCGGCCGGCCCAAGGGCGCGGCCAACCGCCACG
GCGCGCTGTCGAACCGGATCGCGTGGATGCAGCGGGCCTACGGCCTGGGCCCGGGCGACACGGTGCTGCAGAAGACGCCG
TTCGGTTTCGATGTGTCGGTGTGGGAATTCTTCTGGCCGCTCGCCGTAGGCGCGCGCCTGGCGGTGGCGCCCCCCGGCGC
GCACCGCGAGCCCGCGCACCTGCAGGCGCTCATCCAGCGGCATGCGGTGACGACGCTGCACTTCGTGCCCTCCATGCTGC
AGGCCCTGCTGGCGCAGCTGGATGCGCACGCCTGCGCCAGCGTGCGGCGCATCGTGTGCAGCGGCGAGGCGCTGCCGGCC
GAGGCGCGCCGCCAGGTGCTGGAGCGGCTGCCCGGCGTGGCTCTGCACAACCTCTACGGCCCGACGGAGGCCGCCATCGA
CGTCACGCACTGGACCTGCCATGCGCAGGAGCGCGGCCCCGTGCCGATCGGCCGGCCCATCGCCGGGCTGCGCACCCACG
TGCTCGATGCCGCGATGCAGCCCGTGCCGCCGGGCGCTCCGGGCGAGCTGTTCCTGGGCGGCGCCGGGCTCGCGCGCGGC
TATGCCGCCCGGCCGGGCCTCACCGCCGAACGCTTCGTGGCCGATCCGTTCGAGCCGGGCGCGCGGCTCTACCGCACGGG
CGACCTCGTGCGCTGGCGCGGGGATGGCTCCCTGGAATATCTGGGGCGGCTGGACCACCAGGTGAAGATCCGCGGCCAGC
GCATCGAGCTGGGCGAGATCGAGGCGCGCCTGCTGGCCCGGCCCGGCGTGCGCGAGGCCGTGGCGGTGGCCGCGTCCACG
CCCGCGGGCACGGCGCTGGTGGCGTACTGCAGCCCGCACGCGGGCGCCACCCTGGACGGCGAGGCGCTGCGCGCGCGGCT
CGCCGCAGAGCTGCCCGAGGCCATGGTGCCTTCGCAGATCGCGGTGCTGCCGGCCCTGCCGCTGAACGCCAACGGCAAGG
TGGACCGCAAGGCGCTGCCCTCGCTGCAGCCCGCGTCCGCTGCCACCTATACCGCGCCGCAGGGCGAGGTGGAGGAGGCG
CTGGCGCGCATGTGGTGCGAACTGCTGGCGCTGCCGCGCGCCGGCCGCACCGACCACTTCTTCGCCCAGGGCGGCCATTC
GCTGATGGCCATGCAGCTCGTCGCCCGCGTGCGCTCGGGCCTGCAGGCCGAGATTTCGGTGCGGGACGTCTTCCTGCACC
CGCTGCTGGCGGACCTGGCGCGGTGCGTGGAAGCCGCGCGCCCGCAGCGCCCCGTGGCGGACGCGCTGTCGCGCCTGGAT
GCCTTCCTCGACGATATGGAGATTGCCGGATGA

Upstream 100 bases:

>100_bases
CCGCGCATCGCCGACCTGGCGCAGCTCGTGGAGCTGCGGCTGATCGAGGACATCGAGCGCGGCGCCGCACCTTCTTCCGT
TTCCCTCCAGGCCGATTGAC

Downstream 100 bases:

>100_bases
GCGATATGGATGCACTTCTCCCCCAGGCCCGGATGGCCCGGCGCTTCATGCGGCTGACCGACGCGCAGCGCCGCGCCGCC
TACGCGAAGATGCGCGAAGA

Product: amino acid adenylation domain-containing protein

Products: pyrophosphate; AMP; enterobactin; pyrophosphate; L-Seryl-AMP [C]

Alternate protein names: Tyrocidine synthase III; ATP-dependent asparagine adenylase; AsnA; Asparagine activase; ATP-dependent glutamine adenylase; GlnA; Glutamine activase; ATP-dependent tyrosine adenylase; TyrA; Tyrosine activase; ATP-dependent valine adenylase; ValA; Valine activase; ATP-dependent ornithine adenylase; OrnA; Ornithine activase; ATP-dependent leucine adenylase; LeuA; Leucine activase [H]

Number of amino acids: Translated: 1130; Mature: 1129

Protein sequence:

>1130_residues
MSDSPLLSERRARLSPEQQALLRQRLGGRPADASAAGGAEPPPASAVDALPRSGVPEGAEAPLSWAQQGQWFLWRMDPGN
TAYHVGGGLDFEGPLDAAALHAALQTLVRRHEGLRTVFGEGGDGMPWQRVEPAREVPLPCTDLSGLAPAGRDARLEALAR
EVCAQPFDLRRGPLLRCALARLGPREHRLLFMMHHIASDAWTVERILDEWARGYADALEGRAPPDAPPALRYVDFAIWQR
QWLQGPEAARHRDYWTRQLAEEAPVLQIGRGTAAPSPQAPEARDAGAAQHLLAVPAPLARALRQRARAHGTTLFCVLLAG
FHAVLFRHAGHAVQRVGVPVAGRNRPETADVAGVFINTVVMQARPAPQMPLSALLAQVHATALEAREHEDLPFEHVAQVL
RPERTQEGGGLFQCMFNHLGEGGRPLAGWPGLAVRRVDPGLRAAPFGLTLETMEDPGGGLLAAFRYDGAKFTPQEMAEIA
GHYERMLDALAHDPGRPVGEVAMLGDAERARLQAWSAGGEAADLDLPVHQMFERQAALTPDAPALVAEGREWTYAQLDAR
TSRLAHRLRACGVGPEMLVGVALARGSDMVEALLAVLKAGGAYVPLDPELPADRIAYMLGDCAPALVLTDAAHRACLPAA
MAQPVVLLPLEDAPPGDGAEAACLPVALHAEHLAYVIYTSGSTGRPKGAANRHGALSNRIAWMQRAYGLGPGDTVLQKTP
FGFDVSVWEFFWPLAVGARLAVAPPGAHREPAHLQALIQRHAVTTLHFVPSMLQALLAQLDAHACASVRRIVCSGEALPA
EARRQVLERLPGVALHNLYGPTEAAIDVTHWTCHAQERGPVPIGRPIAGLRTHVLDAAMQPVPPGAPGELFLGGAGLARG
YAARPGLTAERFVADPFEPGARLYRTGDLVRWRGDGSLEYLGRLDHQVKIRGQRIELGEIEARLLARPGVREAVAVAAST
PAGTALVAYCSPHAGATLDGEALRARLAAELPEAMVPSQIAVLPALPLNANGKVDRKALPSLQPASAATYTAPQGEVEEA
LARMWCELLALPRAGRTDHFFAQGGHSLMAMQLVARVRSGLQAEISVRDVFLHPLLADLARCVEAARPQRPVADALSRLD
AFLDDMEIAG

Sequences:

>Translated_1130_residues
MSDSPLLSERRARLSPEQQALLRQRLGGRPADASAAGGAEPPPASAVDALPRSGVPEGAEAPLSWAQQGQWFLWRMDPGN
TAYHVGGGLDFEGPLDAAALHAALQTLVRRHEGLRTVFGEGGDGMPWQRVEPAREVPLPCTDLSGLAPAGRDARLEALAR
EVCAQPFDLRRGPLLRCALARLGPREHRLLFMMHHIASDAWTVERILDEWARGYADALEGRAPPDAPPALRYVDFAIWQR
QWLQGPEAARHRDYWTRQLAEEAPVLQIGRGTAAPSPQAPEARDAGAAQHLLAVPAPLARALRQRARAHGTTLFCVLLAG
FHAVLFRHAGHAVQRVGVPVAGRNRPETADVAGVFINTVVMQARPAPQMPLSALLAQVHATALEAREHEDLPFEHVAQVL
RPERTQEGGGLFQCMFNHLGEGGRPLAGWPGLAVRRVDPGLRAAPFGLTLETMEDPGGGLLAAFRYDGAKFTPQEMAEIA
GHYERMLDALAHDPGRPVGEVAMLGDAERARLQAWSAGGEAADLDLPVHQMFERQAALTPDAPALVAEGREWTYAQLDAR
TSRLAHRLRACGVGPEMLVGVALARGSDMVEALLAVLKAGGAYVPLDPELPADRIAYMLGDCAPALVLTDAAHRACLPAA
MAQPVVLLPLEDAPPGDGAEAACLPVALHAEHLAYVIYTSGSTGRPKGAANRHGALSNRIAWMQRAYGLGPGDTVLQKTP
FGFDVSVWEFFWPLAVGARLAVAPPGAHREPAHLQALIQRHAVTTLHFVPSMLQALLAQLDAHACASVRRIVCSGEALPA
EARRQVLERLPGVALHNLYGPTEAAIDVTHWTCHAQERGPVPIGRPIAGLRTHVLDAAMQPVPPGAPGELFLGGAGLARG
YAARPGLTAERFVADPFEPGARLYRTGDLVRWRGDGSLEYLGRLDHQVKIRGQRIELGEIEARLLARPGVREAVAVAAST
PAGTALVAYCSPHAGATLDGEALRARLAAELPEAMVPSQIAVLPALPLNANGKVDRKALPSLQPASAATYTAPQGEVEEA
LARMWCELLALPRAGRTDHFFAQGGHSLMAMQLVARVRSGLQAEISVRDVFLHPLLADLARCVEAARPQRPVADALSRLD
AFLDDMEIAG
>Mature_1129_residues
SDSPLLSERRARLSPEQQALLRQRLGGRPADASAAGGAEPPPASAVDALPRSGVPEGAEAPLSWAQQGQWFLWRMDPGNT
AYHVGGGLDFEGPLDAAALHAALQTLVRRHEGLRTVFGEGGDGMPWQRVEPAREVPLPCTDLSGLAPAGRDARLEALARE
VCAQPFDLRRGPLLRCALARLGPREHRLLFMMHHIASDAWTVERILDEWARGYADALEGRAPPDAPPALRYVDFAIWQRQ
WLQGPEAARHRDYWTRQLAEEAPVLQIGRGTAAPSPQAPEARDAGAAQHLLAVPAPLARALRQRARAHGTTLFCVLLAGF
HAVLFRHAGHAVQRVGVPVAGRNRPETADVAGVFINTVVMQARPAPQMPLSALLAQVHATALEAREHEDLPFEHVAQVLR
PERTQEGGGLFQCMFNHLGEGGRPLAGWPGLAVRRVDPGLRAAPFGLTLETMEDPGGGLLAAFRYDGAKFTPQEMAEIAG
HYERMLDALAHDPGRPVGEVAMLGDAERARLQAWSAGGEAADLDLPVHQMFERQAALTPDAPALVAEGREWTYAQLDART
SRLAHRLRACGVGPEMLVGVALARGSDMVEALLAVLKAGGAYVPLDPELPADRIAYMLGDCAPALVLTDAAHRACLPAAM
AQPVVLLPLEDAPPGDGAEAACLPVALHAEHLAYVIYTSGSTGRPKGAANRHGALSNRIAWMQRAYGLGPGDTVLQKTPF
GFDVSVWEFFWPLAVGARLAVAPPGAHREPAHLQALIQRHAVTTLHFVPSMLQALLAQLDAHACASVRRIVCSGEALPAE
ARRQVLERLPGVALHNLYGPTEAAIDVTHWTCHAQERGPVPIGRPIAGLRTHVLDAAMQPVPPGAPGELFLGGAGLARGY
AARPGLTAERFVADPFEPGARLYRTGDLVRWRGDGSLEYLGRLDHQVKIRGQRIELGEIEARLLARPGVREAVAVAASTP
AGTALVAYCSPHAGATLDGEALRARLAAELPEAMVPSQIAVLPALPLNANGKVDRKALPSLQPASAATYTAPQGEVEEAL
ARMWCELLALPRAGRTDHFFAQGGHSLMAMQLVARVRSGLQAEISVRDVFLHPLLADLARCVEAARPQRPVADALSRLDA
FLDDMEIAG

Specific function: Incorporates six amino acids (for tyrocidine A, Asn, Gln, Tyr, Val, Orn, and Leu) in their L-configuration into the peptide product [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 6 acyl carrier domains [H]

Homologues:

Organism=Homo sapiens, GI45580730, Length=590, Percent_Identity=24.2372881355932, Blast_Score=122, Evalue=3e-27,
Organism=Homo sapiens, GI187761345, Length=537, Percent_Identity=26.8156424581006, Blast_Score=117, Evalue=9e-26,
Organism=Homo sapiens, GI187761343, Length=537, Percent_Identity=26.8156424581006, Blast_Score=117, Evalue=9e-26,
Organism=Homo sapiens, GI42544132, Length=520, Percent_Identity=21.1538461538462, Blast_Score=89, Evalue=3e-17,
Organism=Homo sapiens, GI38505220, Length=504, Percent_Identity=23.2142857142857, Blast_Score=87, Evalue=7e-17,
Organism=Homo sapiens, GI28416953, Length=578, Percent_Identity=23.1833910034602, Blast_Score=83, Evalue=2e-15,
Organism=Homo sapiens, GI156151445, Length=578, Percent_Identity=23.5294117647059, Blast_Score=81, Evalue=5e-15,
Organism=Homo sapiens, GI157311624, Length=505, Percent_Identity=21.7821782178218, Blast_Score=80, Evalue=9e-15,
Organism=Homo sapiens, GI157311622, Length=505, Percent_Identity=21.7821782178218, Blast_Score=80, Evalue=9e-15,
Organism=Homo sapiens, GI122937307, Length=499, Percent_Identity=22.4448897795591, Blast_Score=79, Evalue=2e-14,
Organism=Homo sapiens, GI58082049, Length=503, Percent_Identity=22.2664015904573, Blast_Score=79, Evalue=2e-14,
Organism=Homo sapiens, GI253970489, Length=382, Percent_Identity=23.5602094240838, Blast_Score=71, Evalue=6e-12,
Organism=Homo sapiens, GI8923896, Length=382, Percent_Identity=23.5602094240838, Blast_Score=71, Evalue=6e-12,
Organism=Escherichia coli, GI1786801, Length=678, Percent_Identity=41.740412979351, Blast_Score=430, Evalue=1e-121,
Organism=Escherichia coli, GI145693145, Length=537, Percent_Identity=25.3258845437616, Blast_Score=113, Evalue=7e-26,
Organism=Escherichia coli, GI1788107, Length=538, Percent_Identity=24.3494423791822, Blast_Score=95, Evalue=2e-20,
Organism=Escherichia coli, GI221142682, Length=521, Percent_Identity=23.0326295585413, Blast_Score=94, Evalue=6e-20,
Organism=Escherichia coli, GI1789201, Length=368, Percent_Identity=28.2608695652174, Blast_Score=86, Evalue=1e-17,
Organism=Escherichia coli, GI1786810, Length=527, Percent_Identity=25.8064516129032, Blast_Score=86, Evalue=2e-17,
Organism=Escherichia coli, GI1790505, Length=376, Percent_Identity=24.7340425531915, Blast_Score=85, Evalue=2e-17,
Organism=Caenorhabditis elegans, GI17556356, Length=612, Percent_Identity=24.5098039215686, Blast_Score=126, Evalue=8e-29,
Organism=Caenorhabditis elegans, GI17550940, Length=1083, Percent_Identity=19.7599261311173, Blast_Score=99, Evalue=1e-20,
Organism=Caenorhabditis elegans, GI32564422, Length=425, Percent_Identity=26.3529411764706, Blast_Score=96, Evalue=8e-20,
Organism=Caenorhabditis elegans, GI32564420, Length=425, Percent_Identity=26.3529411764706, Blast_Score=96, Evalue=1e-19,
Organism=Caenorhabditis elegans, GI71982997, Length=582, Percent_Identity=22.8522336769759, Blast_Score=82, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI71983001, Length=582, Percent_Identity=22.8522336769759, Blast_Score=81, Evalue=3e-15,
Organism=Caenorhabditis elegans, GI17560140, Length=377, Percent_Identity=22.8116710875332, Blast_Score=81, Evalue=3e-15,
Organism=Saccharomyces cerevisiae, GI6319591, Length=773, Percent_Identity=24.1914618369987, Blast_Score=206, Evalue=1e-53,
Organism=Saccharomyces cerevisiae, GI6319699, Length=483, Percent_Identity=22.1532091097308, Blast_Score=89, Evalue=4e-18,
Organism=Saccharomyces cerevisiae, GI6319264, Length=581, Percent_Identity=22.7194492254733, Blast_Score=78, Evalue=1e-14,
Organism=Drosophila melanogaster, GI24648676, Length=532, Percent_Identity=33.0827067669173, Blast_Score=240, Evalue=5e-63,
Organism=Drosophila melanogaster, GI24656500, Length=518, Percent_Identity=26.0617760617761, Blast_Score=104, Evalue=5e-22,
Organism=Drosophila melanogaster, GI24582852, Length=375, Percent_Identity=25.6, Blast_Score=87, Evalue=5e-17,
Organism=Drosophila melanogaster, GI24667955, Length=538, Percent_Identity=22.1189591078067, Blast_Score=87, Evalue=5e-17,
Organism=Drosophila melanogaster, GI62472339, Length=538, Percent_Identity=22.1189591078067, Blast_Score=87, Evalue=6e-17,
Organism=Drosophila melanogaster, GI24667959, Length=391, Percent_Identity=23.5294117647059, Blast_Score=86, Evalue=2e-16,
Organism=Drosophila melanogaster, GI24581924, Length=542, Percent_Identity=23.6162361623616, Blast_Score=84, Evalue=8e-16,
Organism=Drosophila melanogaster, GI21355181, Length=500, Percent_Identity=20.8, Blast_Score=76, Evalue=1e-13,
Organism=Drosophila melanogaster, GI21356947, Length=490, Percent_Identity=21.4285714285714, Blast_Score=75, Evalue=2e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010071
- InterPro:   IPR009081
- InterPro:   IPR020845
- InterPro:   IPR000873
- InterPro:   IPR001242
- InterPro:   IPR006163
- InterPro:   IPR020806
- InterPro:   IPR006162
- InterPro:   IPR001031 [H]

Pfam domain/function: PF00501 AMP-binding; PF00668 Condensation; PF00550 PP-binding; PF00975 Thioesterase [H]

EC number: 2.7.7.- [C]

Molecular weight: Translated: 120909; Mature: 120778

Theoretical pI: Translated: 6.73; Mature: 6.73

Prosite motif: PS50075 ACP_DOMAIN ; PS00455 AMP_BINDING

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSDSPLLSERRARLSPEQQALLRQRLGGRPADASAAGGAEPPPASAVDALPRSGVPEGAE
CCCCCCHHHHHHHCCHHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHCCCCCCCCCCC
APLSWAQQGQWFLWRMDPGNTAYHVGGGLDFEGPLDAAALHAALQTLVRRHEGLRTVFGE
CCHHHHCCCCEEEEEECCCCEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHCCHHHHHCC
GGDGMPWQRVEPAREVPLPCTDLSGLAPAGRDARLEALAREVCAQPFDLRRGPLLRCALA
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCHHHHHHHH
RLGPREHRLLFMMHHIASDAWTVERILDEWARGYADALEGRAPPDAPPALRYVDFAIWQR
HCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHH
QWLQGPEAARHRDYWTRQLAEEAPVLQIGRGTAAPSPQAPEARDAGAAQHLLAVPAPLAR
HHHCCCHHHHHHHHHHHHHHHCCCEEEECCCCCCCCCCCCCCCCCCHHHHHHHCCHHHHH
ALRQRARAHGTTLFCVLLAGFHAVLFRHAGHAVQRVGVPVAGRNRPETADVAGVFINTVV
HHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHH
MQARPAPQMPLSALLAQVHATALEAREHEDLPFEHVAQVLRPERTQEGGGLFQCMFNHLG
HHCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHCCCCCCCCCHHHHHHHHHCC
EGGRPLAGWPGLAVRRVDPGLRAAPFGLTLETMEDPGGGLLAAFRYDGAKFTPQEMAEIA
CCCCCCCCCCCCEEEECCCCCCCCCCCCEEEECCCCCCCEEEEEECCCCCCCHHHHHHHH
GHYERMLDALAHDPGRPVGEVAMLGDAERARLQAWSAGGEAADLDLPVHQMFERQAALTP
HHHHHHHHHHHCCCCCCHHHHHCCCCHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHCCCC
DAPALVAEGREWTYAQLDARTSRLAHRLRACGVGPEMLVGVALARGSDMVEALLAVLKAG
CCCHHHHCCCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCHHHHHHHHHHHHCC
GAYVPLDPELPADRIAYMLGDCAPALVLTDAAHRACLPAAMAQPVVLLPLEDAPPGDGAE
CCEECCCCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCCCC
AACLPVALHAEHLAYVIYTSGSTGRPKGAANRHGALSNRIAWMQRAYGLGPGDTVLQKTP
CCHHHHHEECCCEEEEEEECCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCHHHHCCC
FGFDVSVWEFFWPLAVGARLAVAPPGAHREPAHLQALIQRHAVTTLHFVPSMLQALLAQL
CCCCHHHHHHHHHHHHCCEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
DAHACASVRRIVCSGEALPAEARRQVLERLPGVALHNLYGPTEAAIDVTHWTCHAQERGP
HHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCHHHHHCCCCCHHEEEEEEEEEECCCCCC
VPIGRPIAGLRTHVLDAAMQPVPPGAPGELFLGGAGLARGYAARPGLTAERFVADPFEPG
CCCCCCHHHHHHHHHHHHHCCCCCCCCCCEEECCCHHHCCCCCCCCCCHHHHHCCCCCCC
ARLYRTGDLVRWRGDGSLEYLGRLDHQVKIRGQRIELGEIEARLLARPGVREAVAVAAST
HHEEECCCEEEECCCCCHHHHHCCCCEEEEECCEEEHHHHHHHHHCCCCHHHHHHHHCCC
PAGTALVAYCSPHAGATLDGEALRARLAAELPEAMVPSQIAVLPALPLNANGKVDRKALP
CCCCEEEEEECCCCCCCCCHHHHHHHHHHHCHHHHCCCHHHHEECCCCCCCCCCCHHHCC
SLQPASAATYTAPQGEVEEALARMWCELLALPRAGRTDHFFAQGGHSLMAMQLVARVRSG
CCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCHHHCCCHHHHHHHHHHHHHCC
LQAEISVRDVFLHPLLADLARCVEAARPQRPVADALSRLDAFLDDMEIAG
CEEEEHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
SDSPLLSERRARLSPEQQALLRQRLGGRPADASAAGGAEPPPASAVDALPRSGVPEGAE
CCCCCHHHHHHHCCHHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHCCCCCCCCCCC
APLSWAQQGQWFLWRMDPGNTAYHVGGGLDFEGPLDAAALHAALQTLVRRHEGLRTVFGE
CCHHHHCCCCEEEEEECCCCEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHCCHHHHHCC
GGDGMPWQRVEPAREVPLPCTDLSGLAPAGRDARLEALAREVCAQPFDLRRGPLLRCALA
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCHHHHHHHH
RLGPREHRLLFMMHHIASDAWTVERILDEWARGYADALEGRAPPDAPPALRYVDFAIWQR
HCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHH
QWLQGPEAARHRDYWTRQLAEEAPVLQIGRGTAAPSPQAPEARDAGAAQHLLAVPAPLAR
HHHCCCHHHHHHHHHHHHHHHCCCEEEECCCCCCCCCCCCCCCCCCHHHHHHHCCHHHHH
ALRQRARAHGTTLFCVLLAGFHAVLFRHAGHAVQRVGVPVAGRNRPETADVAGVFINTVV
HHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHH
MQARPAPQMPLSALLAQVHATALEAREHEDLPFEHVAQVLRPERTQEGGGLFQCMFNHLG
HHCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHCCCCCCCCCHHHHHHHHHCC
EGGRPLAGWPGLAVRRVDPGLRAAPFGLTLETMEDPGGGLLAAFRYDGAKFTPQEMAEIA
CCCCCCCCCCCCEEEECCCCCCCCCCCCEEEECCCCCCCEEEEEECCCCCCCHHHHHHHH
GHYERMLDALAHDPGRPVGEVAMLGDAERARLQAWSAGGEAADLDLPVHQMFERQAALTP
HHHHHHHHHHHCCCCCCHHHHHCCCCHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHCCCC
DAPALVAEGREWTYAQLDARTSRLAHRLRACGVGPEMLVGVALARGSDMVEALLAVLKAG
CCCHHHHCCCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCHHHHHHHHHHHHCC
GAYVPLDPELPADRIAYMLGDCAPALVLTDAAHRACLPAAMAQPVVLLPLEDAPPGDGAE
CCEECCCCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCCCC
AACLPVALHAEHLAYVIYTSGSTGRPKGAANRHGALSNRIAWMQRAYGLGPGDTVLQKTP
CCHHHHHEECCCEEEEEEECCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCHHHHCCC
FGFDVSVWEFFWPLAVGARLAVAPPGAHREPAHLQALIQRHAVTTLHFVPSMLQALLAQL
CCCCHHHHHHHHHHHHCCEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
DAHACASVRRIVCSGEALPAEARRQVLERLPGVALHNLYGPTEAAIDVTHWTCHAQERGP
HHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCHHHHHCCCCCHHEEEEEEEEEECCCCCC
VPIGRPIAGLRTHVLDAAMQPVPPGAPGELFLGGAGLARGYAARPGLTAERFVADPFEPG
CCCCCCHHHHHHHHHHHHHCCCCCCCCCCEEECCCHHHCCCCCCCCCCHHHHHCCCCCCC
ARLYRTGDLVRWRGDGSLEYLGRLDHQVKIRGQRIELGEIEARLLARPGVREAVAVAAST
HHEEECCCEEEECCCCCHHHHHCCCCEEEEECCEEEHHHHHHHHHCCCCHHHHHHHHCCC
PAGTALVAYCSPHAGATLDGEALRARLAAELPEAMVPSQIAVLPALPLNANGKVDRKALP
CCCCEEEEEECCCCCCCCCHHHHHHHHHHHCHHHHCCCHHHHEECCCCCCCCCCCHHHCC
SLQPASAATYTAPQGEVEEALARMWCELLALPRAGRTDHFFAQGGHSLMAMQLVARVRSG
CCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCHHHCCCHHHHHHHHHHHHHCC
LQAEISVRDVFLHPLLADLARCVEAARPQRPVADALSRLDAFLDDMEIAG
CEEEEHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: Phosphopantetheine. [C]

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: 6 ATP; L-serine; 2,3-dihydroxybenzoate [C]

Specific reaction: 6 ATP + 3 L-serine + 3 2,3-dihydroxybenzoate = 6 pyrophosphate + 6 AMP + enterobactin ATP + L-serine = pyrophosphate + L-Seryl-AMP 6 ATP + 3 L-serine + 3 2,3-dihydroxybenzoate = 6 pyrophosphate + 6 AMP + enterobactin ATP + L-serine = pyrophosphate + L-Ser

General reaction: Transferases; Acyltransferases; Transferring groups other than amino-acyl groups [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9352938; 10801488 [H]