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The map label for this gene is pdxA [H]

Identifier: 120612342

GI number: 120612342

Start: 4074593

End: 4075717

Strand: Reverse

Name: pdxA [H]

Synonym: Aave_3698

Alternate gene names: 120612342

Gene position: 4075717-4074593 (Counterclockwise)

Preceding gene: 120612343

Following gene: 120612340

Centisome position: 76.14

GC content: 75.02

Gene sequence:

>1125_bases
ATGCAGCGGGAAGCGACCGTGGACCACCGTGCAGCGCCGTCCGCATCGGCACCTGCCGCGCCGGCCGGAGGGCTTCCGCT
GCTGGCGGTCACCCAGGGCGATCCGGCCGGCATCGGCCCGGAAATCATCGCCAAGGCCTTCCGCGACGCACCCGATGCGA
TGCGGGGCTGCTTCGTGGTCGGCGGGGTGGAGACGCTGCGCCGCGCCGCACGCTGCATCGCCCGGCCCGGCGAGCCATCC
TTGCCGCTTGCGCTGCTGCAAGCCCCCGAAGAGGCGCGTGCCGTGCCGCCGCGCTGTGTACCCCTGCTGCCGCTGCCGGG
CCTGCCCGGGTCGATCCCGTTCGGCGCCGTGCATGCCGAAGGCGGGCGGGCTGCGGCGGATTGCGTCACCTGGGCCGCCC
GCGCCGCGCTGCGCGGCGAGATCGCCGGGCTCGTCACGGCCCCGCTGCACAAGGAGGCGCTGTCCGCCGCCGGCGTCCAC
CATCCCGGGCATACCGAACTGCTGCAGGCCGAGGCCGCGCGCCATGCCGGCGTGCCGGTCGCGGACATGCCCGTGCGCAT
GATGCTCGCCAGCGACGAGCTGCGCACCGTGCTGGTCAGCATCCACGTGTCCCTGCGCGAGGCCATCGCGGCGGTCACGC
AGGACAACGTCCTGCGCACGCTGGAGATCACGCACGCCGCGCTGCGGCGCGGCCTGGGCCGCGGCCCGCGCATCGGCGTG
GCGGGCCTCAACCCGCACGCGGGCGAAGGCGGGCTTTTCGGCCGCGAGGAGATCGAGGCCATCGCCCCGGCCATCGCCGC
AGCGCGTGCGCTCGGCATCGACGCGCACGGCCCCTTCGCGCCCGACACGGTGTTCATGCGCGCGCGCAGCACGCCGCAGC
GCCCGGGCGAATTCGACGTGGTGCTGGCCATGTACCACGACCAGGGACTGATCCCCGTCAAGTACCTGGGCGTGGACAAG
GGCGTGAACGTCACGCTCGGCCTGCCCCTGGTGCGCACCAGTCCGGACCACGGCACGGCCTTCGACATCGCCGGCCGCGG
CGTGGCCGACGCATCGAGCCTCGTCGAGGCCGTGCTGGCGGCGCGCCGCCTGGCGGGTCCGGTTCCCGGCGCCGTCAGCG
CCTGA

Upstream 100 bases:

>100_bases
TGGTCACCCACGACGAGGCCCTGGCCGCTCGCTGCGACCGCGTCGTGCGGCTGGTCTCCGGCGCGCTGGCGGCGGCCTGA
CGCTGCCCGCCCGACACGCC

Downstream 100 bases:

>100_bases
GACTGTCGCGGATCTCGCGCAGCAGCACGATGTCCTCCGGCGGCGCGGCCGGGGTGGCGGGCGGTGCGGGCGGCGCCGCG
CGCTTGAGCCGGTTGATTTG

Product: 4-hydroxythreonine-4-phosphate dehydrogenase

Products: NA

Alternate protein names: 4-(phosphohydroxy)-L-threonine dehydrogenase [H]

Number of amino acids: Translated: 374; Mature: 374

Protein sequence:

>374_residues
MQREATVDHRAAPSASAPAAPAGGLPLLAVTQGDPAGIGPEIIAKAFRDAPDAMRGCFVVGGVETLRRAARCIARPGEPS
LPLALLQAPEEARAVPPRCVPLLPLPGLPGSIPFGAVHAEGGRAAADCVTWAARAALRGEIAGLVTAPLHKEALSAAGVH
HPGHTELLQAEAARHAGVPVADMPVRMMLASDELRTVLVSIHVSLREAIAAVTQDNVLRTLEITHAALRRGLGRGPRIGV
AGLNPHAGEGGLFGREEIEAIAPAIAAARALGIDAHGPFAPDTVFMRARSTPQRPGEFDVVLAMYHDQGLIPVKYLGVDK
GVNVTLGLPLVRTSPDHGTAFDIAGRGVADASSLVEAVLAARRLAGPVPGAVSA

Sequences:

>Translated_374_residues
MQREATVDHRAAPSASAPAAPAGGLPLLAVTQGDPAGIGPEIIAKAFRDAPDAMRGCFVVGGVETLRRAARCIARPGEPS
LPLALLQAPEEARAVPPRCVPLLPLPGLPGSIPFGAVHAEGGRAAADCVTWAARAALRGEIAGLVTAPLHKEALSAAGVH
HPGHTELLQAEAARHAGVPVADMPVRMMLASDELRTVLVSIHVSLREAIAAVTQDNVLRTLEITHAALRRGLGRGPRIGV
AGLNPHAGEGGLFGREEIEAIAPAIAAARALGIDAHGPFAPDTVFMRARSTPQRPGEFDVVLAMYHDQGLIPVKYLGVDK
GVNVTLGLPLVRTSPDHGTAFDIAGRGVADASSLVEAVLAARRLAGPVPGAVSA
>Mature_374_residues
MQREATVDHRAAPSASAPAAPAGGLPLLAVTQGDPAGIGPEIIAKAFRDAPDAMRGCFVVGGVETLRRAARCIARPGEPS
LPLALLQAPEEARAVPPRCVPLLPLPGLPGSIPFGAVHAEGGRAAADCVTWAARAALRGEIAGLVTAPLHKEALSAAGVH
HPGHTELLQAEAARHAGVPVADMPVRMMLASDELRTVLVSIHVSLREAIAAVTQDNVLRTLEITHAALRRGLGRGPRIGV
AGLNPHAGEGGLFGREEIEAIAPAIAAARALGIDAHGPFAPDTVFMRARSTPQRPGEFDVVLAMYHDQGLIPVKYLGVDK
GVNVTLGLPLVRTSPDHGTAFDIAGRGVADASSLVEAVLAARRLAGPVPGAVSA

Specific function: Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP) [H]

COG id: COG1995

COG function: function code H; Pyridoxal phosphate biosynthesis protein

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the pdxA family [H]

Homologues:

Organism=Escherichia coli, GI1786237, Length=340, Percent_Identity=38.2352941176471, Blast_Score=197, Evalue=1e-51,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005255 [H]

Pfam domain/function: PF04166 PdxA [H]

EC number: =1.1.1.262 [H]

Molecular weight: Translated: 38359; Mature: 38359

Theoretical pI: Translated: 7.43; Mature: 7.43

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQREATVDHRAAPSASAPAAPAGGLPLLAVTQGDPAGIGPEIIAKAFRDAPDAMRGCFVV
CCCCCCCCCCCCCCCCCCCCCCCCCCEEEEECCCCCCCCHHHHHHHHHCCHHHHHCEEEE
GGVETLRRAARCIARPGEPSLPLALLQAPEEARAVPPRCVPLLPLPGLPGSIPFGAVHAE
CCHHHHHHHHHHHCCCCCCCCCHHHHCCCHHHHCCCCCCEEEECCCCCCCCCCCCEEECC
GGRAAADCVTWAARAALRGEIAGLVTAPLHKEALSAAGVHHPGHTELLQAEAARHAGVPV
CCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCCC
ADMPVRMMLASDELRTVLVSIHVSLREAIAAVTQDNVLRTLEITHAALRRGLGRGPRIGV
CCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCCCCEEE
AGLNPHAGEGGLFGREEIEAIAPAIAAARALGIDAHGPFAPDTVFMRARSTPQRPGEFDV
ECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEECCCCCCCCCCEEE
VLAMYHDQGLIPVKYLGVDKGVNVTLGLPLVRTSPDHGTAFDIAGRGVADASSLVEAVLA
EEEEECCCCCCEEEEECCCCCCEEEECCEEEEECCCCCCEEEECCCCCCCHHHHHHHHHH
ARRLAGPVPGAVSA
HHHHCCCCCCCCCC
>Mature Secondary Structure
MQREATVDHRAAPSASAPAAPAGGLPLLAVTQGDPAGIGPEIIAKAFRDAPDAMRGCFVV
CCCCCCCCCCCCCCCCCCCCCCCCCCEEEEECCCCCCCCHHHHHHHHHCCHHHHHCEEEE
GGVETLRRAARCIARPGEPSLPLALLQAPEEARAVPPRCVPLLPLPGLPGSIPFGAVHAE
CCHHHHHHHHHHHCCCCCCCCCHHHHCCCHHHHCCCCCCEEEECCCCCCCCCCCCEEECC
GGRAAADCVTWAARAALRGEIAGLVTAPLHKEALSAAGVHHPGHTELLQAEAARHAGVPV
CCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCCC
ADMPVRMMLASDELRTVLVSIHVSLREAIAAVTQDNVLRTLEITHAALRRGLGRGPRIGV
CCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCCCCEEE
AGLNPHAGEGGLFGREEIEAIAPAIAAARALGIDAHGPFAPDTVFMRARSTPQRPGEFDV
ECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEECCCCCCCCCCEEE
VLAMYHDQGLIPVKYLGVDKGVNVTLGLPLVRTSPDHGTAFDIAGRGVADASSLVEAVLA
EEEEECCCCCCEEEEECCCCCCEEEECCEEEEECCCCCCEEEECCCCCCCHHHHHHHHHH
ARRLAGPVPGAVSA
HHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA