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The map label for this gene is ybhD [H]

Identifier: 120612047

GI number: 120612047

Start: 3750751

End: 3751647

Strand: Direct

Name: ybhD [H]

Synonym: Aave_3393

Alternate gene names: 120612047

Gene position: 3750751-3751647 (Clockwise)

Preceding gene: 120612033

Following gene: 120612052

Centisome position: 70.07

GC content: 70.9

Gene sequence:

>897_bases
ATGCATCTTTCCAGTCGCCACATCGACGCGTTCCTGGCCCTGGCGCAGGAGCGCAGCTTCACGCGCGCGGCGGGCCTGTG
CCACCTCTCGCAGCCGGCGTTCAGCGCCCTGGTGCGCTCGCTGGAAGATGGCCTGGGACTGCGCCTGTTCGACCGCAGCA
CGCGCCATGTGGAGCTGACGCCGGAAGGCCTGCAGTTCCTGGATTCCGCGCGGCGCCTGCGCGTGGAGATCGACAGCGCG
ATCGGCAGGGCGCGAGACGCTGCGCAACTGCGGCGCGGCCGGGTGTCCCTGGCGCTGCTACCGTCGCTGGCCGCCGGCTG
GCTGCCCGGGCTCCTGGCCGGCTTCCGGGCCGACCATCCGCAGATCGAACTCGACATCGCCGACGTGCTGTCCGAGCCCT
GCATCGAGCGCGTGGCGTCGGGCCGCGCGGACTTCGCGCTGGCGGCCATCCGGGCCGACACGCCCTCCCTGCAGGCCGAA
CCGTTCTGCAGCGACAGCTTCCATCTCGTATGCCGCGCCGACCATCCGCTCGCGAAACGCCGCCCCCGCGGCGGCCTGCA
GGTGCAGGATCTCGCGCCCTGGCCGTTCGTGCACCTCGCGCGCACCAGCAGCGTGCGGCAATACCTCGAGGCCGCCATCC
ATCCCCACGCCATGAACACACTGATGGAGGTCGAGCAGCTCGCCACCGTCATGGGCATGGTGCGCGCGGGCATCGGCATC
AGCGTGGTGCCCACGCTCACGCTCTTCCATTTCTCGCAGCCCGGCCTCGTGACTCGGCCGCTGTCGCTGCCGTCCCTTAC
CCGGCAGATCTTCCTCGTGCGCCGGCGCGACCGCGACCTGTCCATCGCCGCGCGGGAGCTCTACCGCAGGGTGATGGAAA
ACCGCCCAAGGGCGTAA

Upstream 100 bases:

>100_bases
GGCGCCATGGCTTGTTTCGTGAAATAGATTGTTAAGATGGATTCATCTGTTTTTCCGATCAATCCACCGGCCGCATCCAC
CACGCCGCCCGCCCCCAGCC

Downstream 100 bases:

>100_bases
GGAGGGAAATAGACCGTCCCGCGGGCACTAGCTGTTGAGTCTCACGAGGTTGTTCACACCCGGAATGCGTGTGATGGGAG
GCTGATGGCCGAGCGCGGAG

Product: LysR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 298; Mature: 298

Protein sequence:

>298_residues
MHLSSRHIDAFLALAQERSFTRAAGLCHLSQPAFSALVRSLEDGLGLRLFDRSTRHVELTPEGLQFLDSARRLRVEIDSA
IGRARDAAQLRRGRVSLALLPSLAAGWLPGLLAGFRADHPQIELDIADVLSEPCIERVASGRADFALAAIRADTPSLQAE
PFCSDSFHLVCRADHPLAKRRPRGGLQVQDLAPWPFVHLARTSSVRQYLEAAIHPHAMNTLMEVEQLATVMGMVRAGIGI
SVVPTLTLFHFSQPGLVTRPLSLPSLTRQIFLVRRRDRDLSIAARELYRRVMENRPRA

Sequences:

>Translated_298_residues
MHLSSRHIDAFLALAQERSFTRAAGLCHLSQPAFSALVRSLEDGLGLRLFDRSTRHVELTPEGLQFLDSARRLRVEIDSA
IGRARDAAQLRRGRVSLALLPSLAAGWLPGLLAGFRADHPQIELDIADVLSEPCIERVASGRADFALAAIRADTPSLQAE
PFCSDSFHLVCRADHPLAKRRPRGGLQVQDLAPWPFVHLARTSSVRQYLEAAIHPHAMNTLMEVEQLATVMGMVRAGIGI
SVVPTLTLFHFSQPGLVTRPLSLPSLTRQIFLVRRRDRDLSIAARELYRRVMENRPRA
>Mature_298_residues
MHLSSRHIDAFLALAQERSFTRAAGLCHLSQPAFSALVRSLEDGLGLRLFDRSTRHVELTPEGLQFLDSARRLRVEIDSA
IGRARDAAQLRRGRVSLALLPSLAAGWLPGLLAGFRADHPQIELDIADVLSEPCIERVASGRADFALAAIRADTPSLQAE
PFCSDSFHLVCRADHPLAKRRPRGGLQVQDLAPWPFVHLARTSSVRQYLEAAIHPHAMNTLMEVEQLATVMGMVRAGIGI
SVVPTLTLFHFSQPGLVTRPLSLPSLTRQIFLVRRRDRDLSIAARELYRRVMENRPRA

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI145693105, Length=283, Percent_Identity=31.8021201413428, Blast_Score=159, Evalue=2e-40,
Organism=Escherichia coli, GI1788748, Length=299, Percent_Identity=32.7759197324415, Blast_Score=129, Evalue=2e-31,
Organism=Escherichia coli, GI157672245, Length=286, Percent_Identity=30.4195804195804, Blast_Score=116, Evalue=2e-27,
Organism=Escherichia coli, GI1789204, Length=260, Percent_Identity=31.9230769230769, Blast_Score=114, Evalue=6e-27,
Organism=Escherichia coli, GI1790399, Length=276, Percent_Identity=27.8985507246377, Blast_Score=105, Evalue=5e-24,
Organism=Escherichia coli, GI1787879, Length=254, Percent_Identity=31.1023622047244, Blast_Score=93, Evalue=2e-20,
Organism=Escherichia coli, GI1788887, Length=270, Percent_Identity=28.1481481481481, Blast_Score=93, Evalue=2e-20,
Organism=Escherichia coli, GI87081904, Length=213, Percent_Identity=29.1079812206573, Blast_Score=85, Evalue=4e-18,
Organism=Escherichia coli, GI1787530, Length=247, Percent_Identity=27.1255060728745, Blast_Score=85, Evalue=6e-18,
Organism=Escherichia coli, GI1788481, Length=291, Percent_Identity=25.4295532646048, Blast_Score=84, Evalue=1e-17,
Organism=Escherichia coli, GI1790262, Length=258, Percent_Identity=26.7441860465116, Blast_Score=74, Evalue=1e-14,
Organism=Escherichia coli, GI2367136, Length=255, Percent_Identity=24.3137254901961, Blast_Score=73, Evalue=2e-14,
Organism=Escherichia coli, GI1789173, Length=163, Percent_Identity=34.3558282208589, Blast_Score=72, Evalue=4e-14,
Organism=Escherichia coli, GI1787601, Length=172, Percent_Identity=26.1627906976744, Blast_Score=70, Evalue=1e-13,
Organism=Escherichia coli, GI1787806, Length=241, Percent_Identity=24.896265560166, Blast_Score=67, Evalue=2e-12,
Organism=Escherichia coli, GI1787589, Length=149, Percent_Identity=34.2281879194631, Blast_Score=67, Evalue=2e-12,
Organism=Escherichia coli, GI1790208, Length=255, Percent_Identity=26.2745098039216, Blast_Score=65, Evalue=4e-12,
Organism=Escherichia coli, GI1788296, Length=232, Percent_Identity=24.5689655172414, Blast_Score=65, Evalue=7e-12,
Organism=Escherichia coli, GI1790783, Length=143, Percent_Identity=25.8741258741259, Blast_Score=63, Evalue=2e-11,
Organism=Escherichia coli, GI1788297, Length=245, Percent_Identity=23.265306122449, Blast_Score=62, Evalue=4e-11,
Organism=Escherichia coli, GI145693193, Length=146, Percent_Identity=29.4520547945205, Blast_Score=61, Evalue=7e-11,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 33075; Mature: 33075

Theoretical pI: Translated: 10.85; Mature: 10.85

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHLSSRHIDAFLALAQERSFTRAAGLCHLSQPAFSALVRSLEDGLGLRLFDRSTRHVELT
CCCCHHHHHHHHHHHHHHHHHHHHCCHHCCCHHHHHHHHHHHCCCCEEEECCCCCEEEEC
PEGLQFLDSARRLRVEIDSAIGRARDAAQLRRGRVSLALLPSLAAGWLPGLLAGFRADHP
HHHHHHHHHHHHHEEHHHHHHCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCC
QIELDIADVLSEPCIERVASGRADFALAAIRADTPSLQAEPFCSDSFHLVCRADHPLAKR
EEEEEHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCCCCCCCCCCEEEEEECCCCHHHC
RPRGGLQVQDLAPWPFVHLARTSSVRQYLEAAIHPHAMNTLMEVEQLATVMGMVRAGIGI
CCCCCCEECCCCCCCHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHCCCC
SVVPTLTLFHFSQPGLVTRPLSLPSLTRQIFLVRRRDRDLSIAARELYRRVMENRPRA
CHHHHHHHHCCCCCCCEECCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MHLSSRHIDAFLALAQERSFTRAAGLCHLSQPAFSALVRSLEDGLGLRLFDRSTRHVELT
CCCCHHHHHHHHHHHHHHHHHHHHCCHHCCCHHHHHHHHHHHCCCCEEEECCCCCEEEEC
PEGLQFLDSARRLRVEIDSAIGRARDAAQLRRGRVSLALLPSLAAGWLPGLLAGFRADHP
HHHHHHHHHHHHHEEHHHHHHCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCC
QIELDIADVLSEPCIERVASGRADFALAAIRADTPSLQAEPFCSDSFHLVCRADHPLAKR
EEEEEHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCCCCCCCCCCEEEEEECCCCHHHC
RPRGGLQVQDLAPWPFVHLARTSSVRQYLEAAIHPHAMNTLMEVEQLATVMGMVRAGIGI
CCCCCCEECCCCCCCHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHCCCC
SVVPTLTLFHFSQPGLVTRPLSLPSLTRQIFLVRRRDRDLSIAARELYRRVMENRPRA
CHHHHHHHHCCCCCCCEECCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8905232; 9278503 [H]