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The map label for this gene is caiD [C]

Identifier: 120612032

GI number: 120612032

Start: 3731104

End: 3732195

Strand: Reverse

Name: caiD [C]

Synonym: Aave_3378

Alternate gene names: 120612032

Gene position: 3732195-3731104 (Counterclockwise)

Preceding gene: 120612034

Following gene: 120612027

Centisome position: 69.72

GC content: 71.52

Gene sequence:

>1092_bases
ATGGATGCAACGCAACGCGACGTGCTGGCCGAGGTGCGCGGACAGGTGGGCTTCATCACGCTGAACCGCCCGCGCGCGCT
CAACGCCCTGTCGCTGGGCATGGTGCGCGACCTGATGGAGGCGCTGCTGCGCTGGCGGTCGGACCCGGCCGTGCACGCCG
TGGCGATCCGCGGCACGAACAAGGAAGGCGCCTTCGGCGCGTTCTGCGCGGGCGGGGACATCCGTTTCCTGCACCAGGCC
GGCAGCACCGGCAACCCGCAGCTGGAAGACTTCTTCACCGAGGAATACGCCCTCAACCACCTGATCCACACCTTCGGCAA
GCCCTACATCGCCTTCATGGACGGCATCGTCATGGGCGGCGGCATGGGCATCAGCCAGGGCGGCAGCCTGCGCATCGTCA
CGGAGCGCACGAAGATGGCGATGCCCGAGACGGCCATCGGCCTGTTCCCGGACGTGGGCGGCGGCTACTTCCTGTCGCGC
TGCCCCGGCCGCACGGGCGAGTGGCTGGCGCTGACGGGCGACACCATTGGCGCGGGCGATGCGGTGGCGCTGGGCCTGGC
CGACGGCTGCATGCCCGCCGAGGCCCAGCACGGCGTCTGGGACGGGCTGGCCACGCAGCGTTTCGACGATGGCGCCGCCA
TCGAACGCTGGGTGGCCACGCATTTCACCCCGCCCACGCCCGCCGCCACGGCCGACCGCGCGCGCATCGACGCGGCCTTC
GGCCGGGAGAGCGTGCCGGCCATTGTCGCGGCGCTGGAGGCCGACGGCAGCGACTGGGCACGCGCCACGGTGACCACGCT
GCGCAAGCGGTCACCGCTGATGCTGCACGTGGTGCTGGAGCAGATCCGGCGCGCGCGGGACATGGACCTGGCCGCCGACC
TGCGCATGGAGCGCGACATGGTGCGCCACTGCTTTTACCTGCGGCCCGGCCAGAGCGAGACGGTGGAGGGCATCCGCGCG
CTCGCGGTGGACAAAGACCATGCGCCCCGCTGGAACCCGGCGCGCATCGAGGACGTCACGCCCGCGATGTGGCAGCCTTT
CTTCGACAGTCCCTGGCCCGCGCATTCCCATCCGCTGGCCGGCCTGCGGTGA

Upstream 100 bases:

>100_bases
GCAGCGCTCCGGGCAGGTCCTGTAGGAGACCGGGCACACCGCGCGGCCTGCGGCACAATTTCCGGCACGTTCCAACACAG
GATTCCAAGGAGACTATCGA

Downstream 100 bases:

>100_bases
ATCACAACTGCGGATGGACGGCCGTGGCGATGGCCAGCAGCGCCTCGCGGGGCAGCGGGCCGCTCAACGCGTAGCCGAAG
CCGTCCTCCACCCAGTAGAA

Product: 3-hydroxyisobutyryl-CoA hydrolase

Products: NA

Alternate protein names: 3-hydroxypropionyl-CoA dehydratase [H]

Number of amino acids: Translated: 363; Mature: 363

Protein sequence:

>363_residues
MDATQRDVLAEVRGQVGFITLNRPRALNALSLGMVRDLMEALLRWRSDPAVHAVAIRGTNKEGAFGAFCAGGDIRFLHQA
GSTGNPQLEDFFTEEYALNHLIHTFGKPYIAFMDGIVMGGGMGISQGGSLRIVTERTKMAMPETAIGLFPDVGGGYFLSR
CPGRTGEWLALTGDTIGAGDAVALGLADGCMPAEAQHGVWDGLATQRFDDGAAIERWVATHFTPPTPAATADRARIDAAF
GRESVPAIVAALEADGSDWARATVTTLRKRSPLMLHVVLEQIRRARDMDLAADLRMERDMVRHCFYLRPGQSETVEGIRA
LAVDKDHAPRWNPARIEDVTPAMWQPFFDSPWPAHSHPLAGLR

Sequences:

>Translated_363_residues
MDATQRDVLAEVRGQVGFITLNRPRALNALSLGMVRDLMEALLRWRSDPAVHAVAIRGTNKEGAFGAFCAGGDIRFLHQA
GSTGNPQLEDFFTEEYALNHLIHTFGKPYIAFMDGIVMGGGMGISQGGSLRIVTERTKMAMPETAIGLFPDVGGGYFLSR
CPGRTGEWLALTGDTIGAGDAVALGLADGCMPAEAQHGVWDGLATQRFDDGAAIERWVATHFTPPTPAATADRARIDAAF
GRESVPAIVAALEADGSDWARATVTTLRKRSPLMLHVVLEQIRRARDMDLAADLRMERDMVRHCFYLRPGQSETVEGIRA
LAVDKDHAPRWNPARIEDVTPAMWQPFFDSPWPAHSHPLAGLR
>Mature_363_residues
MDATQRDVLAEVRGQVGFITLNRPRALNALSLGMVRDLMEALLRWRSDPAVHAVAIRGTNKEGAFGAFCAGGDIRFLHQA
GSTGNPQLEDFFTEEYALNHLIHTFGKPYIAFMDGIVMGGGMGISQGGSLRIVTERTKMAMPETAIGLFPDVGGGYFLSR
CPGRTGEWLALTGDTIGAGDAVALGLADGCMPAEAQHGVWDGLATQRFDDGAAIERWVATHFTPPTPAATADRARIDAAF
GRESVPAIVAALEADGSDWARATVTTLRKRSPLMLHVVLEQIRRARDMDLAADLRMERDMVRHCFYLRPGQSETVEGIRA
LAVDKDHAPRWNPARIEDVTPAMWQPFFDSPWPAHSHPLAGLR

Specific function: Plays a role in autotrophic carbon fixation via the 3- hydroxypropionate/4-hydroxybutyrate cycle. Catalyzes the reversible dehydration of 3-hydroxypropionyl-CoA to form acryloyl- CoA, and the reversible dehydration of (S)-3-hydroxybutyryl-CoA to form crot

COG id: COG1024

COG function: function code I; Enoyl-CoA hydratase/carnithine racemase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the enoyl-CoA hydratase/isomerase family [H]

Homologues:

Organism=Homo sapiens, GI37594471, Length=354, Percent_Identity=36.1581920903955, Blast_Score=224, Evalue=1e-58,
Organism=Homo sapiens, GI37594469, Length=310, Percent_Identity=36.4516129032258, Blast_Score=199, Evalue=2e-51,
Organism=Homo sapiens, GI194097323, Length=193, Percent_Identity=36.2694300518135, Blast_Score=105, Evalue=9e-23,
Organism=Escherichia coli, GI221142681, Length=177, Percent_Identity=28.2485875706215, Blast_Score=66, Evalue=3e-12,
Organism=Escherichia coli, GI1787659, Length=189, Percent_Identity=25.3968253968254, Blast_Score=65, Evalue=6e-12,
Organism=Caenorhabditis elegans, GI25144160, Length=362, Percent_Identity=39.7790055248619, Blast_Score=246, Evalue=1e-65,
Organism=Caenorhabditis elegans, GI25144157, Length=362, Percent_Identity=39.5027624309392, Blast_Score=246, Evalue=1e-65,
Organism=Caenorhabditis elegans, GI25145438, Length=186, Percent_Identity=30.6451612903226, Blast_Score=82, Evalue=3e-16,
Organism=Caenorhabditis elegans, GI17554946, Length=184, Percent_Identity=29.3478260869565, Blast_Score=78, Evalue=7e-15,
Organism=Caenorhabditis elegans, GI17540714, Length=183, Percent_Identity=25.1366120218579, Blast_Score=67, Evalue=1e-11,
Organism=Saccharomyces cerevisiae, GI6320241, Length=374, Percent_Identity=28.8770053475936, Blast_Score=136, Evalue=4e-33,
Organism=Drosophila melanogaster, GI28571730, Length=348, Percent_Identity=39.367816091954, Blast_Score=229, Evalue=2e-60,
Organism=Drosophila melanogaster, GI28571729, Length=348, Percent_Identity=39.367816091954, Blast_Score=229, Evalue=3e-60,
Organism=Drosophila melanogaster, GI20129971, Length=191, Percent_Identity=34.0314136125654, Blast_Score=100, Evalue=2e-21,
Organism=Drosophila melanogaster, GI24653477, Length=191, Percent_Identity=34.0314136125654, Blast_Score=100, Evalue=2e-21,
Organism=Drosophila melanogaster, GI24653139, Length=178, Percent_Identity=31.4606741573034, Blast_Score=70, Evalue=3e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014748
- InterPro:   IPR001753
- InterPro:   IPR018376 [H]

Pfam domain/function: PF00378 ECH [H]

EC number: =4.2.1.116 [H]

Molecular weight: Translated: 39497; Mature: 39497

Theoretical pI: Translated: 6.29; Mature: 6.29

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
3.9 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDATQRDVLAEVRGQVGFITLNRPRALNALSLGMVRDLMEALLRWRSDPAVHAVAIRGTN
CCCHHHHHHHHHCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCC
KEGAFGAFCAGGDIRFLHQAGSTGNPQLEDFFTEEYALNHLIHTFGKPYIAFMDGIVMGG
CCCCCEEEECCCCEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCC
GMGISQGGSLRIVTERTKMAMPETAIGLFPDVGGGYFLSRCPGRTGEWLALTGDTIGAGD
CCCCCCCCCEEEEECHHHHCCCCHHHCCCCCCCCCHHHHCCCCCCCCEEEEECCCCCCCC
AVALGLADGCMPAEAQHGVWDGLATQRFDDGAAIERWVATHFTPPTPAATADRARIDAAF
EEEEECCCCCCCCCCCCCCHHCHHHHCCCCCHHHHHHHHHCCCCCCCCCCCHHHHHHHHH
GRESVPAIVAALEADGSDWARATVTTLRKRSPLMLHVVLEQIRRARDMDLAADLRMERDM
CCCCHHHHHHEEECCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHH
VRHCFYLRPGQSETVEGIRALAVDKDHAPRWNPARIEDVTPAMWQPFFDSPWPAHSHPLA
HHHHEECCCCCCHHHHHHHHHEECCCCCCCCCCCCCCCCCHHHHCCCCCCCCCCCCCCCC
GLR
CCC
>Mature Secondary Structure
MDATQRDVLAEVRGQVGFITLNRPRALNALSLGMVRDLMEALLRWRSDPAVHAVAIRGTN
CCCHHHHHHHHHCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCC
KEGAFGAFCAGGDIRFLHQAGSTGNPQLEDFFTEEYALNHLIHTFGKPYIAFMDGIVMGG
CCCCCEEEECCCCEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCC
GMGISQGGSLRIVTERTKMAMPETAIGLFPDVGGGYFLSRCPGRTGEWLALTGDTIGAGD
CCCCCCCCCEEEEECHHHHCCCCHHHCCCCCCCCCHHHHCCCCCCCCEEEEECCCCCCCC
AVALGLADGCMPAEAQHGVWDGLATQRFDDGAAIERWVATHFTPPTPAATADRARIDAAF
EEEEECCCCCCCCCCCCCCHHCHHHHCCCCCHHHHHHHHHCCCCCCCCCCCHHHHHHHHH
GRESVPAIVAALEADGSDWARATVTTLRKRSPLMLHVVLEQIRRARDMDLAADLRMERDM
CCCCHHHHHHEEECCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHH
VRHCFYLRPGQSETVEGIRALAVDKDHAPRWNPARIEDVTPAMWQPFFDSPWPAHSHPLA
HHHHEECCCCCCHHHHHHHHHEECCCCCCCCCCCCCCCCCHHHHCCCCCCCCCCCCCCCC
GLR
CCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA