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The map label for this gene is pheA [H]

Identifier: 120611938

GI number: 120611938

Start: 3628262

End: 3629362

Strand: Direct

Name: pheA [H]

Synonym: Aave_3282

Alternate gene names: 120611938

Gene position: 3628262-3629362 (Clockwise)

Preceding gene: 120611937

Following gene: 120611939

Centisome position: 67.78

GC content: 68.76

Gene sequence:

>1101_bases
ATGTCCCAATCCCCTCAAGCGTCCCCCGATCTCGCCAGCCTGCGGGTGCAGATCGACAACATCGACCAGCAGTTGCTGAC
CCTCCTGAACCAGCGCGCGCTGGTGGCCGAGCGCGTCGGCGAGGTCAAGAAACGCGAAGGCACCCCGTTCTTTCGCCCGG
ACCGCGTCGCCCAGGTCATCGACAAGGTGCAGCACGCCAATCCGGGACCGCTCAAGGGCGCCCACGTCGCAGCGATCTGG
CGCGAGATCATGTCGGCATGCCTGGCCCTCGAGTCGCCCCAGCGCGTGGCGGTGCTCGGCCCGGCCGGCACATTCTGCGA
GCAGGCGGCCGTGGAGTTCTTCGGCGGCGCCGCGGACCTCATGTACTGCGCCAACTTCGACGAGGTGTTCCATGCCACGG
CGGCCGGCAGCGCACAGTACGGCGTGGTCGGTGTCGAGAACTCGGTGGAAGGCGTGGTGACACGCTCGCTCGACCTGTTC
CTGCACACCCCCTGCCACGTGGTGGGTGAAGTGAGCCTGCTGGTGCGCCACAACCTGCTGCGCCTGTCCAACTCCCTGGA
CGGCATCGAGGTGGTACTGGCCCATCCCCAGGCGTTGGCCCAGTGCCAGGCCTGGTTGTCCAAGCACCTGCCGCACGCGG
AGCGCCGTCCGGTCTCCAGCAATGCCGAGGGCGCGCGGCTGGCGGCAGGGAACCCTGCGTGGGCGGGCATCGCGAGCGAG
CGCGCCGGCGCGCAGTTCGGCCTGCATCTGGTGTCGCACGCCATCCAGGACGATGCCTACAACCGCACGCGCTTCGCCGT
CATCTGCCTGCCGCACACGCTGCAGATGCCGCCGGCTTCCGGCAAGGACTGCACCAGCCTCGTGGTGTCGGTGCCCAACC
GCCCGGGCGCGGTGCACGACCTGCTGGTGCCGCTCAAAACGCACGGTGTTTCCATGACCCGCTTCGAGTCGCGCCCCGCG
CGCACGGGCCAGTGGGAATACTATTTCTACATCGACCTCGACGGCCACCCCAGCCAGCCCCACGTGGCCAAGGCCCTGGA
GGAGCTGCGTTCGCTCTGCGCGTTCTACAAGGTGCTCGGCGCCTATCCGGTGGCGCCGTGA

Upstream 100 bases:

>100_bases
GTGGAGGCGCTCGTGGCCTACATGCAAGAATTCGAACAGCGCAGCGCCTGAGACGGCGCGCCGCGCCCTATCGCCCGCTG
CCCGCAGCCCCGACCGATCC

Downstream 100 bases:

>100_bases
GCGAAGCAGTCACTCCGGTATTCGAGCAGCTGGGCCTCCTGGGCTGCGGACTGATGGGCGGGTCGTTCGCGCTGGCGATG
AAGAAGGCCGGACTGGTCAA

Product: chorismate mutase

Products: NA

Alternate protein names: Chorismate mutase; CM; Prephenate dehydratase; PDT [H]

Number of amino acids: Translated: 366; Mature: 365

Protein sequence:

>366_residues
MSQSPQASPDLASLRVQIDNIDQQLLTLLNQRALVAERVGEVKKREGTPFFRPDRVAQVIDKVQHANPGPLKGAHVAAIW
REIMSACLALESPQRVAVLGPAGTFCEQAAVEFFGGAADLMYCANFDEVFHATAAGSAQYGVVGVENSVEGVVTRSLDLF
LHTPCHVVGEVSLLVRHNLLRLSNSLDGIEVVLAHPQALAQCQAWLSKHLPHAERRPVSSNAEGARLAAGNPAWAGIASE
RAGAQFGLHLVSHAIQDDAYNRTRFAVICLPHTLQMPPASGKDCTSLVVSVPNRPGAVHDLLVPLKTHGVSMTRFESRPA
RTGQWEYYFYIDLDGHPSQPHVAKALEELRSLCAFYKVLGAYPVAP

Sequences:

>Translated_366_residues
MSQSPQASPDLASLRVQIDNIDQQLLTLLNQRALVAERVGEVKKREGTPFFRPDRVAQVIDKVQHANPGPLKGAHVAAIW
REIMSACLALESPQRVAVLGPAGTFCEQAAVEFFGGAADLMYCANFDEVFHATAAGSAQYGVVGVENSVEGVVTRSLDLF
LHTPCHVVGEVSLLVRHNLLRLSNSLDGIEVVLAHPQALAQCQAWLSKHLPHAERRPVSSNAEGARLAAGNPAWAGIASE
RAGAQFGLHLVSHAIQDDAYNRTRFAVICLPHTLQMPPASGKDCTSLVVSVPNRPGAVHDLLVPLKTHGVSMTRFESRPA
RTGQWEYYFYIDLDGHPSQPHVAKALEELRSLCAFYKVLGAYPVAP
>Mature_365_residues
SQSPQASPDLASLRVQIDNIDQQLLTLLNQRALVAERVGEVKKREGTPFFRPDRVAQVIDKVQHANPGPLKGAHVAAIWR
EIMSACLALESPQRVAVLGPAGTFCEQAAVEFFGGAADLMYCANFDEVFHATAAGSAQYGVVGVENSVEGVVTRSLDLFL
HTPCHVVGEVSLLVRHNLLRLSNSLDGIEVVLAHPQALAQCQAWLSKHLPHAERRPVSSNAEGARLAAGNPAWAGIASER
AGAQFGLHLVSHAIQDDAYNRTRFAVICLPHTLQMPPASGKDCTSLVVSVPNRPGAVHDLLVPLKTHGVSMTRFESRPAR
TGQWEYYFYIDLDGHPSQPHVAKALEELRSLCAFYKVLGAYPVAP

Specific function: L-phenylalanine biosynthesis. [C]

COG id: COG0077

COG function: function code E; Prephenate dehydratase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 prephenate dehydratase domain [H]

Homologues:

Organism=Escherichia coli, GI1788951, Length=376, Percent_Identity=28.9893617021277, Blast_Score=154, Evalue=9e-39,
Organism=Saccharomyces cerevisiae, GI6324013, Length=322, Percent_Identity=27.0186335403727, Blast_Score=77, Evalue=4e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002912
- InterPro:   IPR008242
- InterPro:   IPR002701
- InterPro:   IPR020822
- InterPro:   IPR010957
- InterPro:   IPR001086
- InterPro:   IPR018528 [H]

Pfam domain/function: PF01842 ACT; PF01817 CM_2; PF00800 PDT [H]

EC number: =5.4.99.5; =4.2.1.51 [H]

Molecular weight: Translated: 39631; Mature: 39499

Theoretical pI: Translated: 7.08; Mature: 7.08

Prosite motif: PS00858 PREPHENATE_DEHYDR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.2 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
2.2 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSQSPQASPDLASLRVQIDNIDQQLLTLLNQRALVAERVGEVKKREGTPFFRPDRVAQVI
CCCCCCCCCCCEEEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHH
DKVQHANPGPLKGAHVAAIWREIMSACLALESPQRVAVLGPAGTFCEQAAVEFFGGAADL
HHHHCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCEEEEECCCHHHHHHHHHHHHCCHHHH
MYCANFDEVFHATAAGSAQYGVVGVENSVEGVVTRSLDLFLHTPCHVVGEVSLLVRHNLL
HEECCHHHHHHHHCCCCCCCCEEECCCCCCHHHHHHHHHEECCCHHHHHHHHHHHHHHHH
RLSNSLDGIEVVLAHPQALAQCQAWLSKHLPHAERRPVSSNAEGARLAAGNPAWAGIASE
HHHCCCCCEEEEEECHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCEEECCCCCCCCCHHH
RAGAQFGLHLVSHAIQDDAYNRTRFAVICLPHTLQMPPASGKDCTSLVVSVPNRPGAVHD
HCCHHHHHHHHHHHHHCCCCCCCEEEEEEECCEECCCCCCCCCHHHHEEECCCCCCCHHH
LLVPLKTHGVSMTRFESRPARTGQWEYYFYIDLDGHPSQPHVAKALEELRSLCAFYKVLG
HHHHHHHCCCEEEEECCCCCCCCCEEEEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHH
AYPVAP
CCCCCC
>Mature Secondary Structure 
SQSPQASPDLASLRVQIDNIDQQLLTLLNQRALVAERVGEVKKREGTPFFRPDRVAQVI
CCCCCCCCCCEEEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHH
DKVQHANPGPLKGAHVAAIWREIMSACLALESPQRVAVLGPAGTFCEQAAVEFFGGAADL
HHHHCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCEEEEECCCHHHHHHHHHHHHCCHHHH
MYCANFDEVFHATAAGSAQYGVVGVENSVEGVVTRSLDLFLHTPCHVVGEVSLLVRHNLL
HEECCHHHHHHHHCCCCCCCCEEECCCCCCHHHHHHHHHEECCCHHHHHHHHHHHHHHHH
RLSNSLDGIEVVLAHPQALAQCQAWLSKHLPHAERRPVSSNAEGARLAAGNPAWAGIASE
HHHCCCCCEEEEEECHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCEEECCCCCCCCCHHH
RAGAQFGLHLVSHAIQDDAYNRTRFAVICLPHTLQMPPASGKDCTSLVVSVPNRPGAVHD
HCCHHHHHHHHHHHHHCCCCCCCEEEEEEECCEECCCCCCCCCHHHHEEECCCCCCCHHH
LLVPLKTHGVSMTRFESRPARTGQWEYYFYIDLDGHPSQPHVAKALEELRSLCAFYKVLG
HHHHHHHCCCEEEEECCCCCCCCCEEEEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHH
AYPVAP
CCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10094619 [H]