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The map label for this gene is dnaJ [H]

Identifier: 120611886

GI number: 120611886

Start: 3558543

End: 3558824

Strand: Reverse

Name: dnaJ [H]

Synonym: Aave_3228

Alternate gene names: 120611886

Gene position: 3558824-3558543 (Counterclockwise)

Preceding gene: 120611887

Following gene: 120611885

Centisome position: 66.49

GC content: 67.02

Gene sequence:

>282_bases
ATGACTGACCACTACGCCGCCCTCGGTCTGAGCGCGACCGCGAGCCTGGCCGACATCAAGAAGGCGTTCCGCCAGAAGGC
GGCCTTCTACCACCCCGACCGCAATCCCTCGCCGGATGCGGCCGAGCGCTTCCGCGCGGCCCAGAAGGCCTACGAGGTGC
TGTCGGACGATGCCGCGCGCCAGGCCTACGACGACAACCGCCGCCGCAACCTGCTCGACGATCCGCTCCAGACGGCGCGG
GAGATCTGGCAGTCCTATTTCAAGAACGTGCTTTCCTCGTGA

Upstream 100 bases:

>100_bases
CCCGGGCACGTGCGCCGCTCTTGGTGTATAACCGCGCCTCCCCGGACACCCGCGGCGCCGCGCCCCGCGCCTGCCGGCAC
CACCGATCCATCCCCCGAGC

Downstream 100 bases:

>100_bases
AACCCTCTCCTTTCTTCCATGACCTGCGCTCGGCCTACCAGGCCGAGCTCGACGACCTCGCCCAGGACTCCGAGGGCAAG
GACGTGCTGCGCAAGCGCCT

Product: heat shock protein DnaJ domain-containing protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 93; Mature: 92

Protein sequence:

>93_residues
MTDHYAALGLSATASLADIKKAFRQKAAFYHPDRNPSPDAAERFRAAQKAYEVLSDDAARQAYDDNRRRNLLDDPLQTAR
EIWQSYFKNVLSS

Sequences:

>Translated_93_residues
MTDHYAALGLSATASLADIKKAFRQKAAFYHPDRNPSPDAAERFRAAQKAYEVLSDDAARQAYDDNRRRNLLDDPLQTAR
EIWQSYFKNVLSS
>Mature_92_residues
TDHYAALGLSATASLADIKKAFRQKAAFYHPDRNPSPDAAERFRAAQKAYEVLSDDAARQAYDDNRRRNLLDDPLQTARE
IWQSYFKNVLSS

Specific function: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, dnaK-independent fashion. Unfolded proteins bind initially to dnaJ; upon

COG id: COG0484

COG function: function code O; DnaJ-class molecular chaperone with C-terminal Zn finger domain

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 J domain [H]

Homologues:

Organism=Homo sapiens, GI6631085, Length=62, Percent_Identity=51.6129032258064, Blast_Score=69, Evalue=6e-13,
Organism=Homo sapiens, GI7706495, Length=72, Percent_Identity=48.6111111111111, Blast_Score=66, Evalue=5e-12,
Organism=Homo sapiens, GI194328760, Length=63, Percent_Identity=49.2063492063492, Blast_Score=66, Evalue=8e-12,
Organism=Homo sapiens, GI194328758, Length=63, Percent_Identity=49.2063492063492, Blast_Score=65, Evalue=8e-12,
Organism=Homo sapiens, GI8922563, Length=67, Percent_Identity=52.2388059701493, Blast_Score=65, Evalue=9e-12,
Organism=Homo sapiens, GI5453690, Length=62, Percent_Identity=46.7741935483871, Blast_Score=65, Evalue=2e-11,
Organism=Homo sapiens, GI56687498, Length=62, Percent_Identity=50, Blast_Score=64, Evalue=2e-11,
Organism=Homo sapiens, GI201862518, Length=62, Percent_Identity=46.7741935483871, Blast_Score=64, Evalue=3e-11,
Organism=Homo sapiens, GI201862587, Length=62, Percent_Identity=46.7741935483871, Blast_Score=64, Evalue=3e-11,
Organism=Homo sapiens, GI56549115, Length=62, Percent_Identity=46.7741935483871, Blast_Score=63, Evalue=4e-11,
Organism=Homo sapiens, GI23503241, Length=66, Percent_Identity=46.969696969697, Blast_Score=63, Evalue=5e-11,
Organism=Escherichia coli, GI1786197, Length=63, Percent_Identity=47.6190476190476, Blast_Score=62, Evalue=9e-12,
Organism=Escherichia coli, GI1787235, Length=64, Percent_Identity=45.3125, Blast_Score=60, Evalue=4e-11,
Organism=Caenorhabditis elegans, GI17507263, Length=63, Percent_Identity=49.2063492063492, Blast_Score=65, Evalue=7e-12,
Organism=Caenorhabditis elegans, GI17534355, Length=62, Percent_Identity=45.1612903225806, Blast_Score=62, Evalue=8e-11,
Organism=Saccharomyces cerevisiae, GI6324265, Length=63, Percent_Identity=52.3809523809524, Blast_Score=71, Evalue=3e-14,
Organism=Saccharomyces cerevisiae, GI6322194, Length=69, Percent_Identity=50.7246376811594, Blast_Score=67, Evalue=4e-13,
Organism=Saccharomyces cerevisiae, GI6324103, Length=79, Percent_Identity=43.0379746835443, Blast_Score=62, Evalue=2e-11,
Organism=Saccharomyces cerevisiae, GI6320888, Length=64, Percent_Identity=46.875, Blast_Score=61, Evalue=3e-11,
Organism=Drosophila melanogaster, GI24658562, Length=63, Percent_Identity=52.3809523809524, Blast_Score=66, Evalue=5e-12,
Organism=Drosophila melanogaster, GI24658555, Length=63, Percent_Identity=52.3809523809524, Blast_Score=66, Evalue=5e-12,
Organism=Drosophila melanogaster, GI18858081, Length=72, Percent_Identity=47.2222222222222, Blast_Score=65, Evalue=6e-12,
Organism=Drosophila melanogaster, GI85726398, Length=62, Percent_Identity=48.3870967741936, Blast_Score=65, Evalue=1e-11,
Organism=Drosophila melanogaster, GI24646562, Length=64, Percent_Identity=46.875, Blast_Score=64, Evalue=2e-11,
Organism=Drosophila melanogaster, GI24646560, Length=64, Percent_Identity=46.875, Blast_Score=64, Evalue=2e-11,
Organism=Drosophila melanogaster, GI24646558, Length=64, Percent_Identity=46.875, Blast_Score=64, Evalue=2e-11,
Organism=Drosophila melanogaster, GI24646556, Length=64, Percent_Identity=46.875, Blast_Score=64, Evalue=2e-11,
Organism=Drosophila melanogaster, GI21357547, Length=64, Percent_Identity=46.875, Blast_Score=64, Evalue=2e-11,
Organism=Drosophila melanogaster, GI45552811, Length=63, Percent_Identity=50.7936507936508, Blast_Score=63, Evalue=3e-11,
Organism=Drosophila melanogaster, GI45549272, Length=63, Percent_Identity=50.7936507936508, Blast_Score=63, Evalue=4e-11,
Organism=Drosophila melanogaster, GI24668492, Length=78, Percent_Identity=42.3076923076923, Blast_Score=63, Evalue=4e-11,
Organism=Drosophila melanogaster, GI45552813, Length=63, Percent_Identity=50.7936507936508, Blast_Score=63, Evalue=4e-11,
Organism=Drosophila melanogaster, GI24654066, Length=75, Percent_Identity=42.6666666666667, Blast_Score=62, Evalue=1e-10,
Organism=Drosophila melanogaster, GI24654070, Length=75, Percent_Identity=42.6666666666667, Blast_Score=62, Evalue=1e-10,
Organism=Drosophila melanogaster, GI24654068, Length=75, Percent_Identity=42.6666666666667, Blast_Score=62, Evalue=1e-10,
Organism=Drosophila melanogaster, GI24654072, Length=75, Percent_Identity=42.6666666666667, Blast_Score=62, Evalue=1e-10,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012724
- InterPro:   IPR002939
- InterPro:   IPR001623
- InterPro:   IPR018253
- InterPro:   IPR008971
- InterPro:   IPR015609
- InterPro:   IPR003095
- InterPro:   IPR001305 [H]

Pfam domain/function: PF00226 DnaJ; PF01556 DnaJ_C; PF00684 DnaJ_CXXCXGXG [H]

EC number: NA

Molecular weight: Translated: 10593; Mature: 10462

Theoretical pI: Translated: 8.89; Mature: 8.89

Prosite motif: PS00636 DNAJ_1 ; PS50076 DNAJ_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
1.1 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
0.0 %Met     (Mature Protein)
0.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTDHYAALGLSATASLADIKKAFRQKAAFYHPDRNPSPDAAERFRAAQKAYEVLSDDAAR
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHH
QAYDDNRRRNLLDDPLQTAREIWQSYFKNVLSS
HHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
TDHYAALGLSATASLADIKKAFRQKAAFYHPDRNPSPDAAERFRAAQKAYEVLSDDAAR
CCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHH
QAYDDNRRRNLLDDPLQTAREIWQSYFKNVLSS
HHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12466555 [H]