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The map label for this gene is allR [H]

Identifier: 120611866

GI number: 120611866

Start: 3537373

End: 3538143

Strand: Reverse

Name: allR [H]

Synonym: Aave_3208

Alternate gene names: 120611866

Gene position: 3538143-3537373 (Counterclockwise)

Preceding gene: 120611880

Following gene: 120611865

Centisome position: 66.1

GC content: 71.73

Gene sequence:

>771_bases
ATGCACGGGCATTGCCTTCCCGCCATGAAAGCTTCCCGAACCGAATCCCGGCCCACGCCTTCCGCCGAGCCGCCGCGTCC
ACCCTCCGGGGTGCTGGAACGCGGCATCGCCATCCTCGAGTGTTTCGACGAAGACAGCCTGCGTCTGCCGCTGCGCGACG
TGGCGGAGCGGACCGGGCTGGACAAGGCCACCGCGCTGCGGCTCCTCGGCGTGCTGGTGCGCTCCCGCATGGTCCACCGC
TTCGACAACGGCGACTACGCGCCCGGGCCCGCCCTGCTACACATGGGCATGCTGTACCGGCAGACCTTCGACATCGGCGC
GCGCCTGCAGCCGGCGCTGCAGGCCGTGATGCAGGAAACGGGCGAGACCGTGGCCTTCTACGTGCGCGACGGCGACGAGC
GCGTCTGCCTGTACCGCGAGAACAGTCGCAACGAGGTGCGCCACCATGTGGAGGTGGGCGCGCGCATTCCGCTCACCGCG
GGCGGTTCCTCATCCCACGTGCTGCGCCATTTCACGGGCAGCGAAACGCCGCAGGCCGAGGCCATCGCCCGCGACGGCTT
CGCCATGACGCGGGAGGAGCGCGTGCCCCAGATCGCCTCCGTGGCCGTGCCGGTCTTCGACAGCGACGGCAGCTTCCTGG
GTGCCGTGGTCGTGATCGGCATCGCGCCCCGGCAGAGCGCCACGGCCCAGCGGCGCGCCGTGCAGGTGGTGCGCAGCGCG
CTGCAGGCCCAGGGCTTCAGCAGCCGGCCTCCGCGCGGCTGGCAGGGCTAG

Upstream 100 bases:

>100_bases
GGGGCGTTGATTGGCTTGCGGTATTTCAATGAATGAAATACATTTCAGTTATTAAAACTATAGGCCTGGTCGTCCGGCGC
TGTCAACGGTGGCAGCCCGG

Downstream 100 bases:

>100_bases
GTGTGATGTCTCAATAGGTTGTTCATCCAGGCCCGACCTGGGAAGCTGTGGTTACCAGGCCCCAGCAACTCAGGACAGGA
CACCGGATGAACAGTCATAA

Product: IclR family transcriptional regulator

Products: NA

Alternate protein names: Negative regulator of allantoin and glyoxylate utilization operons [H]

Number of amino acids: Translated: 256; Mature: 256

Protein sequence:

>256_residues
MHGHCLPAMKASRTESRPTPSAEPPRPPSGVLERGIAILECFDEDSLRLPLRDVAERTGLDKATALRLLGVLVRSRMVHR
FDNGDYAPGPALLHMGMLYRQTFDIGARLQPALQAVMQETGETVAFYVRDGDERVCLYRENSRNEVRHHVEVGARIPLTA
GGSSSHVLRHFTGSETPQAEAIARDGFAMTREERVPQIASVAVPVFDSDGSFLGAVVVIGIAPRQSATAQRRAVQVVRSA
LQAQGFSSRPPRGWQG

Sequences:

>Translated_256_residues
MHGHCLPAMKASRTESRPTPSAEPPRPPSGVLERGIAILECFDEDSLRLPLRDVAERTGLDKATALRLLGVLVRSRMVHR
FDNGDYAPGPALLHMGMLYRQTFDIGARLQPALQAVMQETGETVAFYVRDGDERVCLYRENSRNEVRHHVEVGARIPLTA
GGSSSHVLRHFTGSETPQAEAIARDGFAMTREERVPQIASVAVPVFDSDGSFLGAVVVIGIAPRQSATAQRRAVQVVRSA
LQAQGFSSRPPRGWQG
>Mature_256_residues
MHGHCLPAMKASRTESRPTPSAEPPRPPSGVLERGIAILECFDEDSLRLPLRDVAERTGLDKATALRLLGVLVRSRMVHR
FDNGDYAPGPALLHMGMLYRQTFDIGARLQPALQAVMQETGETVAFYVRDGDERVCLYRENSRNEVRHHVEVGARIPLTA
GGSSSHVLRHFTGSETPQAEAIARDGFAMTREERVPQIASVAVPVFDSDGSFLGAVVVIGIAPRQSATAQRRAVQVVRSA
LQAQGFSSRPPRGWQG

Specific function: Negative regulator of allantoin and glyoxylate utilization operons. Binds to the gcl promoter and to the allS- allA intergenic region [H]

COG id: COG1414

COG function: function code K; Transcriptional regulator

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 iclR-ED (iclR effector binding) domain [H]

Homologues:

Organism=Escherichia coli, GI1786715, Length=241, Percent_Identity=24.4813278008299, Blast_Score=74, Evalue=1e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014757
- InterPro:   IPR005471
- InterPro:   IPR011991 [H]

Pfam domain/function: PF09339 HTH_IclR; PF01614 IclR [H]

EC number: NA

Molecular weight: Translated: 27955; Mature: 27955

Theoretical pI: Translated: 8.88; Mature: 8.88

Prosite motif: PS51077 HTH_ICLR ; PS51078 ICLR_ED

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHGHCLPAMKASRTESRPTPSAEPPRPPSGVLERGIAILECFDEDSLRLPLRDVAERTGL
CCCCCCCCHHHCCCCCCCCCCCCCCCCCHHHHHHCHHEEEECCCCCCCCCHHHHHHHCCC
DKATALRLLGVLVRSRMVHRFDNGDYAPGPALLHMGMLYRQTFDIGARLQPALQAVMQET
CHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHC
GETVAFYVRDGDERVCLYRENSRNEVRHHVEVGARIPLTAGGSSSHVLRHFTGSETPQAE
CCEEEEEEECCCCEEEEEECCCHHHHHHHHHCCCCCEEECCCCCCHHHHHCCCCCCCHHH
AIARDGFAMTREERVPQIASVAVPVFDSDGSFLGAVVVIGIAPRQSATAQRRAVQVVRSA
HHHHCCCHHHHHHHCCHHHHEEEEEECCCCCCEEEEEEEECCCCCHHHHHHHHHHHHHHH
LQAQGFSSRPPRGWQG
HHHCCCCCCCCCCCCC
>Mature Secondary Structure
MHGHCLPAMKASRTESRPTPSAEPPRPPSGVLERGIAILECFDEDSLRLPLRDVAERTGL
CCCCCCCCHHHCCCCCCCCCCCCCCCCCHHHHHHCHHEEEECCCCCCCCCHHHHHHHCCC
DKATALRLLGVLVRSRMVHRFDNGDYAPGPALLHMGMLYRQTFDIGARLQPALQAVMQET
CHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHC
GETVAFYVRDGDERVCLYRENSRNEVRHHVEVGARIPLTAGGSSSHVLRHFTGSETPQAE
CCEEEEEEECCCCEEEEEECCCHHHHHHHHHCCCCCEEECCCCCCHHHHHCCCCCCCHHH
AIARDGFAMTREERVPQIASVAVPVFDSDGSFLGAVVVIGIAPRQSATAQRRAVQVVRSA
HHHHCCCHHHHHHHCCHHHHEEEEEECCCCCCEEEEEEEECCCCCHHHHHHHHHHHHHHH
LQAQGFSSRPPRGWQG
HHHCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA