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The map label for this gene is dsbB

Identifier: 120611218

GI number: 120611218

Start: 2798180

End: 2798707

Strand: Direct

Name: dsbB

Synonym: Aave_2549

Alternate gene names: 120611218

Gene position: 2798180-2798707 (Clockwise)

Preceding gene: 120611217

Following gene: 120611221

Centisome position: 52.28

GC content: 69.13

Gene sequence:

>528_bases
ATGGTTTCGAACTGGTTGGATGCCGCACCGCGCCGCGTGCTGGCCCTCATCTCCGCGGCCTGCATCGCGATGCTCGCCTT
CGGCATGTACCTGCAGCACGTGGTCGGCCTCGAGCCGTGCCCCATGTGCATCGTGCAGCGCTACGCGCTCATCGGCGTGG
CGGTGTTCACGGGCCTGGGCAGCCTGCGCGGCGGCCGTGGCTGGTGGATGACCTGGGGCGTGCTGGCGCTGCTGCTGTCC
GGATTCGGCGCCTTCGTGGCGGCGCGCCAGAGCTGGCTGCAGTGGTATCCGCCCGAGATCGCCACCTGCGGCCGCGACTT
CTACGGGATGATCGAGAACTTCCCGATCAGCCGCGCCATTCCCATGATCTTCCGCGGCTCCGGCGATTGCGCCGCCATCG
ACTGGACCTTCCTGGGGGGCAGCATCGCCAACTGGTCGTTCGTCTGCTTCGTCGTGATGGCCCTGGTGCTTCTGGTGATG
CTGCTCCGCGCCCCGCGCCCCGCCCGCGGCGGGTTTTCCGCGGCCTGA

Upstream 100 bases:

>100_bases
CCGCGCCCGCGTTTTTCTGGACCACGCCGCGGGCATCTGACACGCTGCATCCTTGCCGGATGCCGCCTGCGGCGCCCGGG
TTTTCAAGGACAAGGATTCC

Downstream 100 bases:

>100_bases
GCCTCAGGAGCGCTCTGCCGGGCACGGTCCGGGCGGAAAATACTGCACGGCCTGGCCATCGCGCCACGCCGGGGCCTTGT
GCATCACCTGCTCGAAGAGC

Product: disulfide bond formation protein DsbB

Products: NA

Alternate protein names: Disulfide oxidoreductase

Number of amino acids: Translated: 175; Mature: 175

Protein sequence:

>175_residues
MVSNWLDAAPRRVLALISAACIAMLAFGMYLQHVVGLEPCPMCIVQRYALIGVAVFTGLGSLRGGRGWWMTWGVLALLLS
GFGAFVAARQSWLQWYPPEIATCGRDFYGMIENFPISRAIPMIFRGSGDCAAIDWTFLGGSIANWSFVCFVVMALVLLVM
LLRAPRPARGGFSAA

Sequences:

>Translated_175_residues
MVSNWLDAAPRRVLALISAACIAMLAFGMYLQHVVGLEPCPMCIVQRYALIGVAVFTGLGSLRGGRGWWMTWGVLALLLS
GFGAFVAARQSWLQWYPPEIATCGRDFYGMIENFPISRAIPMIFRGSGDCAAIDWTFLGGSIANWSFVCFVVMALVLLVM
LLRAPRPARGGFSAA
>Mature_175_residues
MVSNWLDAAPRRVLALISAACIAMLAFGMYLQHVVGLEPCPMCIVQRYALIGVAVFTGLGSLRGGRGWWMTWGVLALLLS
GFGAFVAARQSWLQWYPPEIATCGRDFYGMIENFPISRAIPMIFRGSGDCAAIDWTFLGGSIANWSFVCFVVMALVLLVM
LLRAPRPARGGFSAA

Specific function: Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein

COG id: COG1495

COG function: function code O; Disulfide bond formation protein DsbB

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the DsbB family

Homologues:

Organism=Escherichia coli, GI1787433, Length=156, Percent_Identity=29.4871794871795, Blast_Score=69, Evalue=1e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): DSBB_ACIAC (A1TQ84)

Other databases:

- EMBL:   CP000512
- RefSeq:   YP_970896.1
- ProteinModelPortal:   A1TQ84
- SMR:   A1TQ84
- STRING:   A1TQ84
- GeneID:   4666830
- GenomeReviews:   CP000512_GR
- KEGG:   aav:Aave_2549
- NMPDR:   fig|397945.5.peg.2184
- eggNOG:   COG1495
- HOGENOM:   HBG637909
- OMA:   WAWARAK
- ProtClustDB:   CLSK951409
- BioCyc:   AAVE397945:AAVE_2549-MONOMER
- GO:   GO:0006810
- HAMAP:   MF_00286
- InterPro:   IPR003752
- InterPro:   IPR022920

Pfam domain/function: PF02600 DsbB

EC number: NA

Molecular weight: Translated: 19057; Mature: 19057

Theoretical pI: Translated: 8.85; Mature: 8.85

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0x13abf878)-; HASH(0x1491ea24)-; HASH(0x15119aa0)-; HASH(0x145646e0)-;

Cys/Met content:

3.4 %Cys     (Translated Protein)
5.1 %Met     (Translated Protein)
8.6 %Cys+Met (Translated Protein)
3.4 %Cys     (Mature Protein)
5.1 %Met     (Mature Protein)
8.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVSNWLDAAPRRVLALISAACIAMLAFGMYLQHVVGLEPCPMCIVQRYALIGVAVFTGLG
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHH
SLRGGRGWWMTWGVLALLLSGFGAFVAARQSWLQWYPPEIATCGRDFYGMIENFPISRAI
HCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHCHHHHHHHHCCCHHHHC
PMIFRGSGDCAAIDWTFLGGSIANWSFVCFVVMALVLLVMLLRAPRPARGGFSAA
HHHEECCCCEEEEEHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCH
>Mature Secondary Structure
MVSNWLDAAPRRVLALISAACIAMLAFGMYLQHVVGLEPCPMCIVQRYALIGVAVFTGLG
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHH
SLRGGRGWWMTWGVLALLLSGFGAFVAARQSWLQWYPPEIATCGRDFYGMIENFPISRAI
HCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHCHHHHHHHHCCCHHHHC
PMIFRGSGDCAAIDWTFLGGSIANWSFVCFVVMALVLLVMLLRAPRPARGGFSAA
HHHEECCCCEEEEEHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCH

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA