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The map label for this gene is cysW [H]

Identifier: 120611216

GI number: 120611216

Start: 2796027

End: 2796974

Strand: Direct

Name: cysW [H]

Synonym: Aave_2547

Alternate gene names: 120611216

Gene position: 2796027-2796974 (Clockwise)

Preceding gene: 120611215

Following gene: 120611217

Centisome position: 52.24

GC content: 70.25

Gene sequence:

>948_bases
ATGAGCAACCACCCGACACGCACCCTCCGCCGTGCCCAGGCAGGCACCACCGAAGCCCCCTGGGTCCGCTGGACGCTGAT
CGGCGTCGCGCTGGCCTTCCTGCTGCTGTTCCTCGTGCTGCCGCTCGCGGCCGTGTTCACCGAGGCGCTGCGCAAGGGCG
TCGGCGCCTACCTGGATGCGCTGCGCGAGCCCGATGCCTGGTCCGCCATCCGCCTCACGCTGATCACGGCCGCCATCGCG
GTGCCGCTCAACCTCGTGTTCGGCGTGGCGGCCGCCTGGGCGATCGCCAAGTACGAGTTCCGCGGCAAGGCCTTCCTCAC
GACGCTGGTGGACCTGCCGTTCTCCGTCTCGCCCGTCGTGGCGGGCCTGGTGTACGTGCTGCTGTTCGGCGCCAACGGCT
GGCTGGGCCCGTGGCTGGCGGCGCACGACATCAAGATCATCTTCGCCGTGCCGGGCATCGTGCTGGCGACCGTGTTCGTC
ACGTTCCCCTTCATCGCGCGTGAGCTCATTCCCCTGATGCAGGCGCAGGGCAGCGACGAGGAGCAGGCCGCGATCGTGCT
CGGTGCGAGCGGCTGGCAGACCTTCTGGCACGTGACGCTGCCCAACATCAAGTGGGGGCTTCTGTACGGCGTCATCCTGT
GCAATGCGCGCGCCATGGGCGAGTTCGGCGCCGTGTCGGTCGTCTCGGGGCACATCCGCGGGCAGACCAACACCATCCCG
CTGCACGTCGAAATCCTCTACAACGAGTACCAGTCCGTCGCGGCCTTCGCGGCGGCCTCGCTGCTGGCCCTGCTGGCGCT
GGTCACCCTGGTGATCAAGACCTTCGCGGAGTGGCGCAGCGAGCAGGAACGCAAGGCCGCCGCCCAGCTTCCGCCCGAGC
GGCCCACACCCACGCCCGCGCCGGTGGCGCCGGGCGCGCCTGCCGCTTCCGCCACGACGACCCGCTGA

Upstream 100 bases:

>100_bases
GTGGCCGTGGTGATGCTGGTCATTTCCTTCGCGCTGCTTTTCATCATCAACGCGCTGCAGGCCTGGCAGCGCAAGAGCAC
ATGATGGCCCGGACGTGCAT

Downstream 100 bases:

>100_bases
TCCAGAACCGGGGAACACACATGAGCATCGAAATCCGCAACATCAGCAAGCAGTTCGGCGACTTCCAGGCCCTGCGGGAC
GTGAGCCTGGACATCCAGTC

Product: sulfate ABC transporter inner membrane subunit CysW

Products: ADP; phosphate; S2O32- [Cytoplasm]; SO42- [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 315; Mature: 314

Protein sequence:

>315_residues
MSNHPTRTLRRAQAGTTEAPWVRWTLIGVALAFLLLFLVLPLAAVFTEALRKGVGAYLDALREPDAWSAIRLTLITAAIA
VPLNLVFGVAAAWAIAKYEFRGKAFLTTLVDLPFSVSPVVAGLVYVLLFGANGWLGPWLAAHDIKIIFAVPGIVLATVFV
TFPFIARELIPLMQAQGSDEEQAAIVLGASGWQTFWHVTLPNIKWGLLYGVILCNARAMGEFGAVSVVSGHIRGQTNTIP
LHVEILYNEYQSVAAFAAASLLALLALVTLVIKTFAEWRSEQERKAAAQLPPERPTPTPAPVAPGAPAASATTTR

Sequences:

>Translated_315_residues
MSNHPTRTLRRAQAGTTEAPWVRWTLIGVALAFLLLFLVLPLAAVFTEALRKGVGAYLDALREPDAWSAIRLTLITAAIA
VPLNLVFGVAAAWAIAKYEFRGKAFLTTLVDLPFSVSPVVAGLVYVLLFGANGWLGPWLAAHDIKIIFAVPGIVLATVFV
TFPFIARELIPLMQAQGSDEEQAAIVLGASGWQTFWHVTLPNIKWGLLYGVILCNARAMGEFGAVSVVSGHIRGQTNTIP
LHVEILYNEYQSVAAFAAASLLALLALVTLVIKTFAEWRSEQERKAAAQLPPERPTPTPAPVAPGAPAASATTTR
>Mature_314_residues
SNHPTRTLRRAQAGTTEAPWVRWTLIGVALAFLLLFLVLPLAAVFTEALRKGVGAYLDALREPDAWSAIRLTLITAAIAV
PLNLVFGVAAAWAIAKYEFRGKAFLTTLVDLPFSVSPVVAGLVYVLLFGANGWLGPWLAAHDIKIIFAVPGIVLATVFVT
FPFIARELIPLMQAQGSDEEQAAIVLGASGWQTFWHVTLPNIKWGLLYGVILCNARAMGEFGAVSVVSGHIRGQTNTIPL
HVEILYNEYQSVAAFAAASLLALLALVTLVIKTFAEWRSEQERKAAAQLPPERPTPTPAPVAPGAPAASATTTR

Specific function: Part of the ABC transporter complex CysAWTP (TC 3.A.1.6.1) involved in sulfate/thiosulfate import. Probably responsible for the translocation of the substrate across the membrane [H]

COG id: COG4208

COG function: function code P; ABC-type sulfate transport system, permease component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI87082099, Length=269, Percent_Identity=53.5315985130111, Blast_Score=304, Evalue=6e-84,
Organism=Escherichia coli, GI1788764, Length=206, Percent_Identity=38.3495145631068, Blast_Score=147, Evalue=7e-37,
Organism=Escherichia coli, GI1786980, Length=234, Percent_Identity=32.9059829059829, Blast_Score=98, Evalue=6e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000515
- InterPro:   IPR011866
- InterPro:   IPR005667 [H]

Pfam domain/function: PF00528 BPD_transp_1 [H]

EC number: NA

Molecular weight: Translated: 33827; Mature: 33696

Theoretical pI: Translated: 9.39; Mature: 9.39

Prosite motif: PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
1.3 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
0.6 %Met     (Mature Protein)
1.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSNHPTRTLRRAQAGTTEAPWVRWTLIGVALAFLLLFLVLPLAAVFTEALRKGVGAYLDA
CCCCHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LREPDAWSAIRLTLITAAIAVPLNLVFGVAAAWAIAKYEFRGKAFLTTLVDLPFSVSPVV
HCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCCHHHHH
AGLVYVLLFGANGWLGPWLAAHDIKIIFAVPGIVLATVFVTFPFIARELIPLMQAQGSDE
HHHHHHHHHCCCCCCCCCHHHCCEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
EQAAIVLGASGWQTFWHVTLPNIKWGLLYGVILCNARAMGEFGAVSVVSGHIRGQTNTIP
CCEEEEEECCCCCEEEEEECCCCHHHHHHHHHHHCCHHCCCCCCHHHHHHCCCCCCCEEE
LHVEILYNEYQSVAAFAAASLLALLALVTLVIKTFAEWRSEQERKAAAQLPPERPTPTPA
EEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCC
PVAPGAPAASATTTR
CCCCCCCCCCCCCCC
>Mature Secondary Structure 
SNHPTRTLRRAQAGTTEAPWVRWTLIGVALAFLLLFLVLPLAAVFTEALRKGVGAYLDA
CCCHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LREPDAWSAIRLTLITAAIAVPLNLVFGVAAAWAIAKYEFRGKAFLTTLVDLPFSVSPVV
HCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCCHHHHH
AGLVYVLLFGANGWLGPWLAAHDIKIIFAVPGIVLATVFVTFPFIARELIPLMQAQGSDE
HHHHHHHHHCCCCCCCCCHHHCCEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
EQAAIVLGASGWQTFWHVTLPNIKWGLLYGVILCNARAMGEFGAVSVVSGHIRGQTNTIP
CCEEEEEECCCCCEEEEEECCCCHHHHHHHHHHHCCHHCCCCCCHHHHHHCCCCCCCEEE
LHVEILYNEYQSVAAFAAASLLALLALVTLVIKTFAEWRSEQERKAAAQLPPERPTPTPA
EEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCC
PVAPGAPAASATTTR
CCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; S2O32- [Periplasm]; H2O; SO42- [Periplasm]; ATP [C]

Specific reaction: ATP + S2O32- [Periplasm] + H2O = ADP + phosphate + S2O32- [Cytoplasm] SO42- [Periplasm] + H2O + ATP = SO42- [Cytoplasm] + phosphate + ADP [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 12471157 [H]