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The map label for this gene is metI [H]

Identifier: 120611206

GI number: 120611206

Start: 2786462

End: 2787127

Strand: Direct

Name: metI [H]

Synonym: Aave_2537

Alternate gene names: 120611206

Gene position: 2786462-2787127 (Clockwise)

Preceding gene: 120611205

Following gene: 120611207

Centisome position: 52.06

GC content: 68.62

Gene sequence:

>666_bases
ATGTTCGAGAACTTTACGGAAATGATGCTGGAGCTGTTCGCCACCTCGCTGTGGGAAACGCTCGTCATGGTGGGCATCTC
GGGCGTGGTCGGGGCGCTGATCGGCATTCCCCTGGGCGTGTTCCTGCGCCTGACCGACCGCGGCGGCGTGCTGGAGAACG
GCCCCGTCAACAAGACCGTGGGCTGGATCGTGAACGCCGTGCGCTCCACGCCGTTCATCATCCTGCTGGTGGCCATCATC
CCGTTCACGCGGCTGATCACCGGGTCGTCCATCGGTACCGCGGCGGCCGTGGTGCCGCTCACCATCGCCGCGGCACCCTT
CGTCGCCCGGCTGGTCGAGGCCTCGCTGCGCGAGGTGGACCCGGGCCTGATCGAGGCCGCCCAGGCCATGGGCGCGACCA
CCTCCCAGATCGTCTGGAAGGTGCTGCTGCCCGAGGCGCTGCCCGGCATCGTGGCCGGCCTCACCATCACCTTCGTCAGC
CTGACCGGCTATTCGGCCATGGCAGGCGCCATCGGTGGCGGCGGGCTGGGCGACCTGGGCATCCGCTACGGCTACCAGCG
GTTCCTGCCGGACATCATGCTGGCCGTGGTGGTCGTGCTGATCTTCTTCGTGCAGGCCGTGCAGAGCCTGGGCGACTGGG
CGGTGCGCCGGTTGAGCCACCGCTGA

Upstream 100 bases:

>100_bases
GGCGAGGCCCCGCGCCTGGCGGCCGCGGTGGCGCAATTGCGCGCCCAGGGCGTGGTGGTGGACGAAGTGAAAGTGGAAGT
GGAAGCGGGAGGCTGAGGCG

Downstream 100 bases:

>100_bases
CGTAGAGCGGCGGCCTTCATGGGCTTGCCCGTGGCACTCGCCCGGCCGTGACACAGGTGCAGCAGGCCGGCGCACCACCG
GCTGGCAGCGGCGGATAGCC

Product: binding-protein-dependent transport systems inner membrane component

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 221; Mature: 221

Protein sequence:

>221_residues
MFENFTEMMLELFATSLWETLVMVGISGVVGALIGIPLGVFLRLTDRGGVLENGPVNKTVGWIVNAVRSTPFIILLVAII
PFTRLITGSSIGTAAAVVPLTIAAAPFVARLVEASLREVDPGLIEAAQAMGATTSQIVWKVLLPEALPGIVAGLTITFVS
LTGYSAMAGAIGGGGLGDLGIRYGYQRFLPDIMLAVVVVLIFFVQAVQSLGDWAVRRLSHR

Sequences:

>Translated_221_residues
MFENFTEMMLELFATSLWETLVMVGISGVVGALIGIPLGVFLRLTDRGGVLENGPVNKTVGWIVNAVRSTPFIILLVAII
PFTRLITGSSIGTAAAVVPLTIAAAPFVARLVEASLREVDPGLIEAAQAMGATTSQIVWKVLLPEALPGIVAGLTITFVS
LTGYSAMAGAIGGGGLGDLGIRYGYQRFLPDIMLAVVVVLIFFVQAVQSLGDWAVRRLSHR
>Mature_221_residues
MFENFTEMMLELFATSLWETLVMVGISGVVGALIGIPLGVFLRLTDRGGVLENGPVNKTVGWIVNAVRSTPFIILLVAII
PFTRLITGSSIGTAAAVVPLTIAAAPFVARLVEASLREVDPGLIEAAQAMGATTSQIVWKVLLPEALPGIVAGLTITFVS
LTGYSAMAGAIGGGGLGDLGIRYGYQRFLPDIMLAVVVVLIFFVQAVQSLGDWAVRRLSHR

Specific function: Part of the binding-protein-dependent transport system for D-methionine. Probably responsible for the translocation of the substrate across the membrane [H]

COG id: COG2011

COG function: function code P; ABC-type metal ion transport system, permease component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1786397, Length=216, Percent_Identity=52.7777777777778, Blast_Score=179, Evalue=1e-46,
Organism=Escherichia coli, GI1789033, Length=195, Percent_Identity=30.7692307692308, Blast_Score=62, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000515 [H]

Pfam domain/function: PF00528 BPD_transp_1 [H]

EC number: NA

Molecular weight: Translated: 23309; Mature: 23309

Theoretical pI: Translated: 5.89; Mature: 5.89

Prosite motif: PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFENFTEMMLELFATSLWETLVMVGISGVVGALIGIPLGVFLRLTDRGGVLENGPVNKTV
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCCCCCCCCCHHHH
GWIVNAVRSTPFIILLVAIIPFTRLITGSSIGTAAAVVPLTIAAAPFVARLVEASLREVD
HHHHHHHHHCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
PGLIEAAQAMGATTSQIVWKVLLPEALPGIVAGLTITFVSLTGYSAMAGAIGGGGLGDLG
HHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHH
IRYGYQRFLPDIMLAVVVVLIFFVQAVQSLGDWAVRRLSHR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MFENFTEMMLELFATSLWETLVMVGISGVVGALIGIPLGVFLRLTDRGGVLENGPVNKTV
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCCCCCCCCCHHHH
GWIVNAVRSTPFIILLVAIIPFTRLITGSSIGTAAAVVPLTIAAAPFVARLVEASLREVD
HHHHHHHHHCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
PGLIEAAQAMGATTSQIVWKVLLPEALPGIVAGLTITFVSLTGYSAMAGAIGGGGLGDLG
HHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHH
IRYGYQRFLPDIMLAVVVVLIFFVQAVQSLGDWAVRRLSHR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 10952301 [H]