Click here to switch to the map view.

The map label for this gene is baeS [H]

Identifier: 120611194

GI number: 120611194

Start: 2770242

End: 2771300

Strand: Reverse

Name: baeS [H]

Synonym: Aave_2525

Alternate gene names: 120611194

Gene position: 2771300-2770242 (Counterclockwise)

Preceding gene: 120611195

Following gene: 120611193

Centisome position: 51.77

GC content: 71.01

Gene sequence:

>1059_bases
ATGAGCGGCTCCCCCGGCCTGCGCCGGCAGGTCATGCTGTCGCTGGGCGTCATGGCCCTGGGCATCATCCTCATCTCGGT
GATCGGCTCCTACGGCTTCTATGCCGTGCTCATGGCGTATTCGCCGTCGAGCATTTCCGAAACCTGGGTGCCGTCGCGGG
TGGAACTGGTCTGGATGCTGGCCACCATGCTCGCCGCGCTGGCCATCGCCGTCGCCGTCGCCGTGCGGCTTTCGCGCCGC
ATCCTCACGCCGCTGAACGCGGTGGCCGAGAGCCTGCGCAAGGTGGCCCAGGGCGACCTGCAGGCCCGCGCCGCCACGGA
CGACCACTCCATGGGCGAGACCGCCCAGCTGGTGCGCGACTTCAACGCCATGGCCGAACGCCTGCAGGCGATGGAGAAGC
AGCGGGCCTTCTGGAACGCGGCCATCGCCCACGAACTGCGCACGCCCGTCACCATCCTGCACGGGCGACTGCAGGGGCTG
ACGGAAGGCGTGTTCGAGCCGAGGGCCGAACTGTTCCAGGGCCTGCTGCGCCACGTGCAGGGCCTGAGCCGGCTGATCGA
AGACCTGCGCATGCTGAGTCTGCGCGACAGCGGGCACCTGGAACTGGAACAGATGCAGGCGGACCTGGCGCAGGAAGTCG
CCGCCGTCGTGCATGCCTTCGAGCCCGACCTGCATGCGCGCGGCTTCACCGTGCAGGCCGACATCGCGGCGCCCTGCACC
GTGACCTGCGACCCGGTACGCATCCGCCAGGCCCTGATCGCCCTCCTGGAAAACGTGCGCAGGCATGCCGACCCGGGCCG
GGTGCGCATCCACGCCCACGTGGCGGACGGCGAGTGCCACCTCAGCGTGGAAGACGAGGGCCCGGGCATGACCGAGGAAC
TCGCCGCCCAGGTCTTCGAGGCCTTCCACCGCGGAGACCCCACCCGCCCGCAGCAGGCCGGCGGCAGCGGCCTGGGCCTG
GCCGTGGTGAAGGCCATCGCGGAAGCCCACGGCGGCCACGCCACCTGCCAGGCCGCGCCCGGCGGAGGCTCCGTGCTCAC
CCTGCACTGGCCCACGTGA

Upstream 100 bases:

>100_bases
ACAGCCACATCAGCAAGCTGCGCAAGAAACTGGAGCCTCTGGGCGTGGAGGGCCTTCCCGTCAGCGTGCGCGGCGTGGGT
TACCGCCTGGGGAGCGGCGA

Downstream 100 bases:

>100_bases
AAGTAGCGCTAGAATCCAGCCCGTCGTGCGCCGCAATGGCGCCACGCGCGGGTGTAGTTCAATGGTAGAACGGCAGCTTC
CCAAGCTTCATACGAGGGTT

Product: integral membrane sensor signal transduction histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 352; Mature: 351

Protein sequence:

>352_residues
MSGSPGLRRQVMLSLGVMALGIILISVIGSYGFYAVLMAYSPSSISETWVPSRVELVWMLATMLAALAIAVAVAVRLSRR
ILTPLNAVAESLRKVAQGDLQARAATDDHSMGETAQLVRDFNAMAERLQAMEKQRAFWNAAIAHELRTPVTILHGRLQGL
TEGVFEPRAELFQGLLRHVQGLSRLIEDLRMLSLRDSGHLELEQMQADLAQEVAAVVHAFEPDLHARGFTVQADIAAPCT
VTCDPVRIRQALIALLENVRRHADPGRVRIHAHVADGECHLSVEDEGPGMTEELAAQVFEAFHRGDPTRPQQAGGSGLGL
AVVKAIAEAHGGHATCQAAPGGGSVLTLHWPT

Sequences:

>Translated_352_residues
MSGSPGLRRQVMLSLGVMALGIILISVIGSYGFYAVLMAYSPSSISETWVPSRVELVWMLATMLAALAIAVAVAVRLSRR
ILTPLNAVAESLRKVAQGDLQARAATDDHSMGETAQLVRDFNAMAERLQAMEKQRAFWNAAIAHELRTPVTILHGRLQGL
TEGVFEPRAELFQGLLRHVQGLSRLIEDLRMLSLRDSGHLELEQMQADLAQEVAAVVHAFEPDLHARGFTVQADIAAPCT
VTCDPVRIRQALIALLENVRRHADPGRVRIHAHVADGECHLSVEDEGPGMTEELAAQVFEAFHRGDPTRPQQAGGSGLGL
AVVKAIAEAHGGHATCQAAPGGGSVLTLHWPT
>Mature_351_residues
SGSPGLRRQVMLSLGVMALGIILISVIGSYGFYAVLMAYSPSSISETWVPSRVELVWMLATMLAALAIAVAVAVRLSRRI
LTPLNAVAESLRKVAQGDLQARAATDDHSMGETAQLVRDFNAMAERLQAMEKQRAFWNAAIAHELRTPVTILHGRLQGLT
EGVFEPRAELFQGLLRHVQGLSRLIEDLRMLSLRDSGHLELEQMQADLAQEVAAVVHAFEPDLHARGFTVQADIAAPCTV
TCDPVRIRQALIALLENVRRHADPGRVRIHAHVADGECHLSVEDEGPGMTEELAAQVFEAFHRGDPTRPQQAGGSGLGLA
VVKAIAEAHGGHATCQAAPGGGSVLTLHWPT

Specific function: Member of the two-component regulatory system BaeS/BaeR. May activate BaeR by phosphorylation [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 histidine kinase domain [H]

Homologues:

Organism=Escherichia coli, GI1788393, Length=275, Percent_Identity=33.4545454545455, Blast_Score=148, Evalue=4e-37,
Organism=Escherichia coli, GI1786783, Length=272, Percent_Identity=31.6176470588235, Blast_Score=119, Evalue=4e-28,
Organism=Escherichia coli, GI1787894, Length=297, Percent_Identity=31.6498316498317, Blast_Score=105, Evalue=5e-24,
Organism=Escherichia coli, GI1786912, Length=219, Percent_Identity=31.5068493150685, Blast_Score=93, Evalue=3e-20,
Organism=Escherichia coli, GI1789149, Length=335, Percent_Identity=24.4776119402985, Blast_Score=87, Evalue=2e-18,
Organism=Escherichia coli, GI1788279, Length=271, Percent_Identity=28.0442804428044, Blast_Score=84, Evalue=1e-17,
Organism=Escherichia coli, GI1786600, Length=274, Percent_Identity=27.007299270073, Blast_Score=84, Evalue=1e-17,
Organism=Escherichia coli, GI1790346, Length=235, Percent_Identity=28.936170212766, Blast_Score=84, Evalue=2e-17,
Organism=Escherichia coli, GI1789808, Length=289, Percent_Identity=26.2975778546713, Blast_Score=83, Evalue=3e-17,
Organism=Escherichia coli, GI1788549, Length=238, Percent_Identity=26.890756302521, Blast_Score=77, Evalue=2e-15,
Organism=Escherichia coli, GI1788713, Length=221, Percent_Identity=26.2443438914027, Blast_Score=75, Evalue=8e-15,
Organism=Escherichia coli, GI48994928, Length=233, Percent_Identity=24.8927038626609, Blast_Score=74, Evalue=1e-14,
Organism=Escherichia coli, GI87081816, Length=246, Percent_Identity=28.0487804878049, Blast_Score=74, Evalue=1e-14,
Organism=Escherichia coli, GI145693157, Length=238, Percent_Identity=24.3697478991597, Blast_Score=72, Evalue=4e-14,
Organism=Escherichia coli, GI1789403, Length=307, Percent_Identity=28.6644951140065, Blast_Score=71, Evalue=8e-14,
Organism=Escherichia coli, GI1790551, Length=282, Percent_Identity=26.9503546099291, Blast_Score=69, Evalue=5e-13,
Organism=Escherichia coli, GI1790436, Length=247, Percent_Identity=28.3400809716599, Blast_Score=66, Evalue=4e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR003660
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF00672 HAMP; PF02518 HATPase_c; PF00512 HisKA [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 37928; Mature: 37797

Theoretical pI: Translated: 6.56; Mature: 6.56

Prosite motif: PS50885 HAMP ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSGSPGLRRQVMLSLGVMALGIILISVIGSYGFYAVLMAYSPSSISETWVPSRVELVWML
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHH
ATMLAALAIAVAVAVRLSRRILTPLNAVAESLRKVAQGDLQARAATDDHSMGETAQLVRD
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHCCCCCCCCCHHHHHHHH
FNAMAERLQAMEKQRAFWNAAIAHELRTPVTILHGRLQGLTEGVFEPRAELFQGLLRHVQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHH
GLSRLIEDLRMLSLRDSGHLELEQMQADLAQEVAAVVHAFEPDLHARGFTVQADIAAPCT
HHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEECCCCCCE
VTCDPVRIRQALIALLENVRRHADPGRVRIHAHVADGECHLSVEDEGPGMTEELAAQVFE
ECCCHHHHHHHHHHHHHHHHHCCCCCEEEEEEEEECCEEEEEECCCCCCHHHHHHHHHHH
AFHRGDPTRPQQAGGSGLGLAVVKAIAEAHGGHATCQAAPGGGSVLTLHWPT
HHHCCCCCCCHHCCCCCHHHHHHHHHHHHCCCCEEEEECCCCCCEEEEECCC
>Mature Secondary Structure 
SGSPGLRRQVMLSLGVMALGIILISVIGSYGFYAVLMAYSPSSISETWVPSRVELVWML
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHH
ATMLAALAIAVAVAVRLSRRILTPLNAVAESLRKVAQGDLQARAATDDHSMGETAQLVRD
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHCCCCCCCCCHHHHHHHH
FNAMAERLQAMEKQRAFWNAAIAHELRTPVTILHGRLQGLTEGVFEPRAELFQGLLRHVQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHH
GLSRLIEDLRMLSLRDSGHLELEQMQADLAQEVAAVVHAFEPDLHARGFTVQADIAAPCT
HHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEECCCCCCE
VTCDPVRIRQALIALLENVRRHADPGRVRIHAHVADGECHLSVEDEGPGMTEELAAQVFE
ECCCHHHHHHHHHHHHHHHHHCCCCCEEEEEEEEECCEEEEEECCCCCCHHHHHHHHHHH
AFHRGDPTRPQQAGGSGLGLAVVKAIAEAHGGHATCQAAPGGGSVLTLHWPT
HHHCCCCCCCHHCCCCCHHHHHHHHHHHHCCCCEEEEECCCCCCEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 8282725; 9097040; 9278503 [H]