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The map label for this gene is dapL [H]

Identifier: 120611156

GI number: 120611156

Start: 2718549

End: 2719751

Strand: Reverse

Name: dapL [H]

Synonym: Aave_2485

Alternate gene names: 120611156

Gene position: 2719751-2718549 (Counterclockwise)

Preceding gene: 120611158

Following gene: 120611155

Centisome position: 50.81

GC content: 70.49

Gene sequence:

>1203_bases
ATGAATCCCCTGCTCACCCATTTGCAGCCCTATCCGTTCGAGCGGCTGCGGCAGCTCTTCGCGGGGGTGCAGCCCCCCGC
CGGCCTCCCGGCGATCAGCCTCGGCATGGGCGAACCCCGCCACCCCACGCCGGCCTTCATCCAGCAGGCCCTGACGGACC
ACCTGGGCGGCCTCGCCAGCTACCCCGCCACCGCGGGCGATCCCCGCCTGCGCGAAGCCTGCGCGCAATGGCTGCACCGG
CGCTACGGCATCGCGGTGGACGCCGCGACCCAGGTCCTGCCCGTGAACGGCTCCCGCGAGGCCCTGTTCGCGTTCGCCCA
GACGGTGATCGACCCCACGCGCGAAGGCGCCACCGTGGTCTGCCCCAATCCCTTCTACCAAATCTACGAAGGCGCCGCCC
TGCTGTCGGGCGCGCAACCGTACTACGCCCCCAGCGACCCGGCACGCAATTTCGCAGTGGACTGGGATGCCGTGCCCGAA
GACGTCTGGAAGCGCACGCAACTGCTCTTCGTCTGCTCGCCGGGCAACCCCACGGGTGCCGTGATGCCGATGGCCGAGTG
GGAAAAGCTCTTCGCGCTCAGCGACCGCCACGGCTTCGTGATCGCCTCGGACGAGTGCTACAGCGAGATCTACTTCCAGG
GCGGCCCGCCGCTCGGCGGCCTGGAAGCCGCGGCGCGCCTGGGCCGCACGGATTTCCGCAACCTCGTCGCCTTCACCAGC
CTGTCCAAGCGCAGCAACGTGCCCGGCCTGCGCAGCGGCTTCGTGGCGGGCGACGCGGCCCTGATGAAGGCTTTCCTGCT
CTACCGCACCTACCACGGCAGCGCCATGGGGCCGGCCGTGCAGGGCGCCAGCATCGCCGCCTGGAGCGACGAGGCGCACG
TGGAAGAGAACCGCGCCCTCTACCGGAGCAAGTTCGAGCAGGTCACGCCGCTGCTGGCGCAGGTGATGGACGTCGCCCTG
CCCGATGCCGGCTTCTACCTGTGGGCCCGCGTGCCCGAGCGCCTGGGGATGGACGACGCGGCATTCGCCCGCGCCCTCCT
CGCTCAATACAATGTGACCGTGCTGCCGGGCAGCTACCTCGCGCGCGAATCCGGCGGCCGCAATCCCGGCGCCGGCCGCG
TGCGCATGGCGCTCGTGGCCGAGGTCGAGGAATGCCTCGAAGCCGCGCGCCGCATCGTGCAATTCATCCAATCCCATCCC
TGA

Upstream 100 bases:

>100_bases
CCCCGGATGGTATTGGCGGGCACTTACGGAGGATTGACAAGGAGGGAATACGACGAGCCGGACCCGGCGGCCTCCCGCGC
AGCCCCGATAATGGCGACCC

Downstream 100 bases:

>100_bases
TTCCCGAACGGACCATGACCCAACAACTGCAGAACATCATCGACACCGCCTGGGAGAACCGCGCGAGCCTCTCGCCCTCC
GCCGCCCCGCGCGAGGTGCA

Product: succinyldiaminopimelate transaminase

Products: NA

Alternate protein names: DAP-AT; DAP-aminotransferase; LL-DAP-aminotransferase [H]

Number of amino acids: Translated: 400; Mature: 400

Protein sequence:

>400_residues
MNPLLTHLQPYPFERLRQLFAGVQPPAGLPAISLGMGEPRHPTPAFIQQALTDHLGGLASYPATAGDPRLREACAQWLHR
RYGIAVDAATQVLPVNGSREALFAFAQTVIDPTREGATVVCPNPFYQIYEGAALLSGAQPYYAPSDPARNFAVDWDAVPE
DVWKRTQLLFVCSPGNPTGAVMPMAEWEKLFALSDRHGFVIASDECYSEIYFQGGPPLGGLEAAARLGRTDFRNLVAFTS
LSKRSNVPGLRSGFVAGDAALMKAFLLYRTYHGSAMGPAVQGASIAAWSDEAHVEENRALYRSKFEQVTPLLAQVMDVAL
PDAGFYLWARVPERLGMDDAAFARALLAQYNVTVLPGSYLARESGGRNPGAGRVRMALVAEVEECLEAARRIVQFIQSHP

Sequences:

>Translated_400_residues
MNPLLTHLQPYPFERLRQLFAGVQPPAGLPAISLGMGEPRHPTPAFIQQALTDHLGGLASYPATAGDPRLREACAQWLHR
RYGIAVDAATQVLPVNGSREALFAFAQTVIDPTREGATVVCPNPFYQIYEGAALLSGAQPYYAPSDPARNFAVDWDAVPE
DVWKRTQLLFVCSPGNPTGAVMPMAEWEKLFALSDRHGFVIASDECYSEIYFQGGPPLGGLEAAARLGRTDFRNLVAFTS
LSKRSNVPGLRSGFVAGDAALMKAFLLYRTYHGSAMGPAVQGASIAAWSDEAHVEENRALYRSKFEQVTPLLAQVMDVAL
PDAGFYLWARVPERLGMDDAAFARALLAQYNVTVLPGSYLARESGGRNPGAGRVRMALVAEVEECLEAARRIVQFIQSHP
>Mature_400_residues
MNPLLTHLQPYPFERLRQLFAGVQPPAGLPAISLGMGEPRHPTPAFIQQALTDHLGGLASYPATAGDPRLREACAQWLHR
RYGIAVDAATQVLPVNGSREALFAFAQTVIDPTREGATVVCPNPFYQIYEGAALLSGAQPYYAPSDPARNFAVDWDAVPE
DVWKRTQLLFVCSPGNPTGAVMPMAEWEKLFALSDRHGFVIASDECYSEIYFQGGPPLGGLEAAARLGRTDFRNLVAFTS
LSKRSNVPGLRSGFVAGDAALMKAFLLYRTYHGSAMGPAVQGASIAAWSDEAHVEENRALYRSKFEQVTPLLAQVMDVAL
PDAGFYLWARVPERLGMDDAAFARALLAQYNVTVLPGSYLARESGGRNPGAGRVRMALVAEVEECLEAARRIVQFIQSHP

Specific function: Involved in the synthesis of meso-diaminopimelate (m-DAP or DL-DAP), required for both lysine and peptidoglycan biosynthesis. Catalyzes the direct conversion of tetrahydrodipicolinate to LL-diaminopimelate, a reaction that requires three enzymes in E.coli

COG id: COG0436

COG function: function code E; Aspartate/tyrosine/aromatic aminotransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family. LL-diaminopimelate aminotransferase subfamily [H]

Homologues:

Organism=Homo sapiens, GI56713256, Length=393, Percent_Identity=22.9007633587786, Blast_Score=87, Evalue=3e-17,
Organism=Homo sapiens, GI56713254, Length=393, Percent_Identity=22.9007633587786, Blast_Score=86, Evalue=4e-17,
Organism=Homo sapiens, GI95147551, Length=259, Percent_Identity=26.2548262548263, Blast_Score=84, Evalue=3e-16,
Organism=Homo sapiens, GI169881279, Length=259, Percent_Identity=26.2548262548263, Blast_Score=84, Evalue=3e-16,
Organism=Escherichia coli, GI1788722, Length=395, Percent_Identity=27.5949367088608, Blast_Score=138, Evalue=6e-34,
Organism=Escherichia coli, GI1786816, Length=372, Percent_Identity=26.8817204301075, Blast_Score=96, Evalue=5e-21,
Organism=Escherichia coli, GI1790797, Length=332, Percent_Identity=23.4939759036145, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI1787909, Length=358, Percent_Identity=24.8603351955307, Blast_Score=67, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI71994476, Length=429, Percent_Identity=24.2424242424242, Blast_Score=86, Evalue=3e-17,
Organism=Caenorhabditis elegans, GI71994472, Length=429, Percent_Identity=24.2424242424242, Blast_Score=86, Evalue=3e-17,
Organism=Caenorhabditis elegans, GI17567369, Length=403, Percent_Identity=21.8362282878412, Blast_Score=81, Evalue=8e-16,
Organism=Saccharomyces cerevisiae, GI6320317, Length=374, Percent_Identity=24.0641711229947, Blast_Score=75, Evalue=2e-14,
Organism=Drosophila melanogaster, GI18859735, Length=410, Percent_Identity=24.390243902439, Blast_Score=74, Evalue=1e-13,
Organism=Drosophila melanogaster, GI28573069, Length=395, Percent_Identity=20, Blast_Score=72, Evalue=7e-13,
Organism=Drosophila melanogaster, GI24646114, Length=395, Percent_Identity=20, Blast_Score=72, Evalue=7e-13,
Organism=Drosophila melanogaster, GI28573067, Length=395, Percent_Identity=20, Blast_Score=72, Evalue=7e-13,
Organism=Drosophila melanogaster, GI28573065, Length=395, Percent_Identity=20, Blast_Score=72, Evalue=7e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004839
- InterPro:   IPR019881
- InterPro:   IPR004838
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00155 Aminotran_1_2 [H]

EC number: =2.6.1.83 [H]

Molecular weight: Translated: 43506; Mature: 43506

Theoretical pI: Translated: 6.32; Mature: 6.32

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNPLLTHLQPYPFERLRQLFAGVQPPAGLPAISLGMGEPRHPTPAFIQQALTDHLGGLAS
CCCHHHHCCCCCHHHHHHHHCCCCCCCCCCEEEECCCCCCCCCHHHHHHHHHHHHCCHHC
YPATAGDPRLREACAQWLHRRYGIAVDAATQVLPVNGSREALFAFAQTVIDPTREGATVV
CCCCCCCHHHHHHHHHHHHHHHCEEEECCCEEEECCCCHHHHHHHHHHHHCCCCCCCEEE
CPNPFYQIYEGAALLSGAQPYYAPSDPARNFAVDWDAVPEDVWKRTQLLFVCSPGNPTGA
CCCHHHHHHCCHHHHCCCCCCCCCCCCCCCEEECCCCCCHHHHCCEEEEEEECCCCCCCC
VMPMAEWEKLFALSDRHGFVIASDECYSEIYFQGGPPLGGLEAAARLGRTDFRNLVAFTS
CCCHHHHHHHHHCCCCCCEEEECCHHHHHHEECCCCCCCHHHHHHHHCHHHHHHHHHHHH
LSKRSNVPGLRSGFVAGDAALMKAFLLYRTYHGSAMGPAVQGASIAAWSDEAHVEENRAL
HHHHCCCCCHHHCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCEEEECCCCHHHHHHHHH
YRSKFEQVTPLLAQVMDVALPDAGFYLWARVPERLGMDDAAFARALLAQYNVTVLPGSYL
HHHHHHHHHHHHHHHHHHHCCCCCCHHEECCHHHCCCCHHHHHHHHHHHCCEEEECCHHH
ARESGGRNPGAGRVRMALVAEVEECLEAARRIVQFIQSHP
HHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MNPLLTHLQPYPFERLRQLFAGVQPPAGLPAISLGMGEPRHPTPAFIQQALTDHLGGLAS
CCCHHHHCCCCCHHHHHHHHCCCCCCCCCCEEEECCCCCCCCCHHHHHHHHHHHHCCHHC
YPATAGDPRLREACAQWLHRRYGIAVDAATQVLPVNGSREALFAFAQTVIDPTREGATVV
CCCCCCCHHHHHHHHHHHHHHHCEEEECCCEEEECCCCHHHHHHHHHHHHCCCCCCCEEE
CPNPFYQIYEGAALLSGAQPYYAPSDPARNFAVDWDAVPEDVWKRTQLLFVCSPGNPTGA
CCCHHHHHHCCHHHHCCCCCCCCCCCCCCCEEECCCCCCHHHHCCEEEEEEECCCCCCCC
VMPMAEWEKLFALSDRHGFVIASDECYSEIYFQGGPPLGGLEAAARLGRTDFRNLVAFTS
CCCHHHHHHHHHCCCCCCEEEECCHHHHHHEECCCCCCCHHHHHHHHCHHHHHHHHHHHH
LSKRSNVPGLRSGFVAGDAALMKAFLLYRTYHGSAMGPAVQGASIAAWSDEAHVEENRAL
HHHHCCCCCHHHCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCEEEECCCCHHHHHHHHH
YRSKFEQVTPLLAQVMDVALPDAGFYLWARVPERLGMDDAAFARALLAQYNVTVLPGSYL
HHHHHHHHHHHHHHHHHHHCCCCCCHHEECCHHHCCCCHHHHHHHHHHHCCEEEECCHHH
ARESGGRNPGAGRVRMALVAEVEECLEAARRIVQFIQSHP
HHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA