Click here to switch to the map view.

The map label for this gene is yjeP [H]

Identifier: 120610841

GI number: 120610841

Start: 2381854

End: 2383167

Strand: Direct

Name: yjeP [H]

Synonym: Aave_2167

Alternate gene names: 120610841

Gene position: 2381854-2383167 (Clockwise)

Preceding gene: 120610840

Following gene: 120610842

Centisome position: 44.5

GC content: 69.33

Gene sequence:

>1314_bases
ATGGATGCCCTCCACGCGCTGATCCGCGATTTCAGCCAATCCCATACCTGGATCGAAGCGGCCGTGCTGGCCGCCTGCCT
GGCGCTCGCCTATTTCGCCAGCCGCGTCCTCGGCCGCCAGCAGCCGCCCGATTCGGTGTGGTTCGGGCGCCGCACGGTCG
ATGGGCTGATGTTCCCGCTGCTGGCACTGGCCCTGGTCTATGCCGCCCGCGTGGGCGTGGAGACGGTGCTGGCGCGGCCC
GTATTCCTGCTGCGCGTGGCGGTGCCGGTGCTCAGCTCGCTGGTGCTGGTCCGGTTCTTCGCGCGCATCCTCGCCAACGC
GTTCCCGAAATCCGCGGCCATGCGGCTGGTGGAGCGCATCGTCTCGTGGCTGGCCTGGGGCGTGGCGGTGCTCTGGATCG
TCGGTCTGTTGCCGGCGGTGCGCGCCGAGCTGGCCGGCGTCGCCATCCATTTCGGCAAGTCGCGGGTCACGGCGCTCACG
CTGATCGAAGGATCGCTCTCGGCCACCGTGGTGATGCTGCTGGCGCTGTGGCTCTCGTCCACCGTGGAGCGGCGCCTGCT
GGACCGGACGATCGTCGATCTTTCCATGCGCAAGGTGGCCGCCAACGCCACGCGGGCGGGGCTGCTGCTGGTGGGCCTGC
TGTTCGCACTCTCGGCCGTGGGGGTGGACCTGACGGCGCTGTCGGTGCTGGGCGGTGCCGTCGGCGTGGGCCTGGGCTTC
GGTTTGCAGAAGCTCGCCTCCAACTACGTGAGCGGCTTCGTGATTTTGCTGGAGCGCTCCCTGCGCATCGGCGACAACGT
GCGCGTGGACGGCTTCGAGGGCCGCATCACCGACATCAAGACCCGCTACACCCTGATCCGCGCGGGCAACGGGCGCGAAT
CCATCGTGCCCAACGAGACGCTCATCACGCAGCGCGTGGAGAACCTCTCGGACGCGGACCGCAAGTTCAACATCACCACG
AACATCACCGTGGGCTACGACAGCGACGTGTCGCGCGTGCAGGCCATCCTCTGCGCAGCCGCGGCCGCCCAGCCGCGCGT
GCTGGCCGACCCGGCGCCGGTGGCCTACCTGGTGAACTTCGCTCCCGACGGGCTGGAATTCAGCCTCAACTTCTGGGTGA
GCGACCCTTCGGCCGGAACGGTCAATCTGCGCTCGGCGATCAACATCGCCATCCTCGAAGGCCTGCGTGCCGATGGGATC
GACATCCCCTATCCGCAGCGCGTGGTGCGCCTGCAGGCCGACGGCCCGCCGCCCGCCGGGCCCCTGCAGGTCGCTCATGT
CGCACAAGCGTCCTCGCCGCCGCCCACGGCGTGA

Upstream 100 bases:

>100_bases
GGCCGGGGCCTTCCCGCCGGGGTAAGCTTGCCTGCTCTCCTGCCGGGGCCACCGCTGCGCTCCGGCCCTGCCGTCCACCG
ATGCCCCGAGGTTCCCGCCC

Downstream 100 bases:

>100_bases
CCGGACACCGCTATACTTCTGCAAAAAGCACGATCGTTCTTTTTTTGTGCGGGGCAGCCGGCCAGCGTGTTCTCCCGGCG
GTTGCCCGCCGTTCCGGCCA

Product: mechanosensitive ion channel protein MscS

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 437; Mature: 437

Protein sequence:

>437_residues
MDALHALIRDFSQSHTWIEAAVLAACLALAYFASRVLGRQQPPDSVWFGRRTVDGLMFPLLALALVYAARVGVETVLARP
VFLLRVAVPVLSSLVLVRFFARILANAFPKSAAMRLVERIVSWLAWGVAVLWIVGLLPAVRAELAGVAIHFGKSRVTALT
LIEGSLSATVVMLLALWLSSTVERRLLDRTIVDLSMRKVAANATRAGLLLVGLLFALSAVGVDLTALSVLGGAVGVGLGF
GLQKLASNYVSGFVILLERSLRIGDNVRVDGFEGRITDIKTRYTLIRAGNGRESIVPNETLITQRVENLSDADRKFNITT
NITVGYDSDVSRVQAILCAAAAAQPRVLADPAPVAYLVNFAPDGLEFSLNFWVSDPSAGTVNLRSAINIAILEGLRADGI
DIPYPQRVVRLQADGPPPAGPLQVAHVAQASSPPPTA

Sequences:

>Translated_437_residues
MDALHALIRDFSQSHTWIEAAVLAACLALAYFASRVLGRQQPPDSVWFGRRTVDGLMFPLLALALVYAARVGVETVLARP
VFLLRVAVPVLSSLVLVRFFARILANAFPKSAAMRLVERIVSWLAWGVAVLWIVGLLPAVRAELAGVAIHFGKSRVTALT
LIEGSLSATVVMLLALWLSSTVERRLLDRTIVDLSMRKVAANATRAGLLLVGLLFALSAVGVDLTALSVLGGAVGVGLGF
GLQKLASNYVSGFVILLERSLRIGDNVRVDGFEGRITDIKTRYTLIRAGNGRESIVPNETLITQRVENLSDADRKFNITT
NITVGYDSDVSRVQAILCAAAAAQPRVLADPAPVAYLVNFAPDGLEFSLNFWVSDPSAGTVNLRSAINIAILEGLRADGI
DIPYPQRVVRLQADGPPPAGPLQVAHVAQASSPPPTA
>Mature_437_residues
MDALHALIRDFSQSHTWIEAAVLAACLALAYFASRVLGRQQPPDSVWFGRRTVDGLMFPLLALALVYAARVGVETVLARP
VFLLRVAVPVLSSLVLVRFFARILANAFPKSAAMRLVERIVSWLAWGVAVLWIVGLLPAVRAELAGVAIHFGKSRVTALT
LIEGSLSATVVMLLALWLSSTVERRLLDRTIVDLSMRKVAANATRAGLLLVGLLFALSAVGVDLTALSVLGGAVGVGLGF
GLQKLASNYVSGFVILLERSLRIGDNVRVDGFEGRITDIKTRYTLIRAGNGRESIVPNETLITQRVENLSDADRKFNITT
NITVGYDSDVSRVQAILCAAAAAQPRVLADPAPVAYLVNFAPDGLEFSLNFWVSDPSAGTVNLRSAINIAILEGLRADGI
DIPYPQRVVRLQADGPPPAGPLQVAHVAQASSPPPTA

Specific function: Unknown

COG id: COG3264

COG function: function code M; Small-conductance mechanosensitive channel

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the mscS (TC 1.A.23) family [H]

Homologues:

Organism=Escherichia coli, GI2367355, Length=210, Percent_Identity=36.1904761904762, Blast_Score=131, Evalue=1e-31,
Organism=Escherichia coli, GI1786670, Length=248, Percent_Identity=31.8548387096774, Blast_Score=127, Evalue=2e-30,
Organism=Escherichia coli, GI1789291, Length=241, Percent_Identity=26.9709543568465, Blast_Score=84, Evalue=1e-17,
Organism=Escherichia coli, GI1787591, Length=272, Percent_Identity=23.5294117647059, Blast_Score=65, Evalue=9e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010920
- InterPro:   IPR011066
- InterPro:   IPR006685
- InterPro:   IPR006686
- InterPro:   IPR011014 [H]

Pfam domain/function: PF00924 MS_channel [H]

EC number: NA

Molecular weight: Translated: 46721; Mature: 46721

Theoretical pI: Translated: 10.01; Mature: 10.01

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
1.6 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDALHALIRDFSQSHTWIEAAVLAACLALAYFASRVLGRQQPPDSVWFGRRTVDGLMFPL
CHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHCCHHHHHHHHHHH
LALALVYAARVGVETVLARPVFLLRVAVPVLSSLVLVRFFARILANAFPKSAAMRLVERI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHH
VSWLAWGVAVLWIVGLLPAVRAELAGVAIHFGKSRVTALTLIEGSLSATVVMLLALWLSS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCCEEEEEEECCCHHHHHHHHHHHHHHH
TVERRLLDRTIVDLSMRKVAANATRAGLLLVGLLFALSAVGVDLTALSVLGGAVGVGLGF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHH
GLQKLASNYVSGFVILLERSLRIGDNVRVDGFEGRITDIKTRYTLIRAGNGRESIVPNET
HHHHHHHHHHHHHHHHHHHHHCCCCCEEECCCCCCEEEEEEEEEEEEECCCCCCCCCCHH
LITQRVENLSDADRKFNITTNITVGYDSDVSRVQAILCAAAAAQPRVLADPAPVAYLVNF
HHHHHHHHHHCCCCEEEEEEEEEECCCCCHHHHHHHHHHHHCCCCCEECCCCCCEEEEEC
APDGLEFSLNFWVSDPSAGTVNLRSAINIAILEGLRADGIDIPYPQRVVRLQADGPPPAG
CCCCCEEEEEEEEECCCCCEEEHHHHHHHHHHHCCCCCCCCCCCCHHEEEEECCCCCCCC
PLQVAHVAQASSPPPTA
CHHHHHHHHCCCCCCCC
>Mature Secondary Structure
MDALHALIRDFSQSHTWIEAAVLAACLALAYFASRVLGRQQPPDSVWFGRRTVDGLMFPL
CHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHCCHHHHHHHHHHH
LALALVYAARVGVETVLARPVFLLRVAVPVLSSLVLVRFFARILANAFPKSAAMRLVERI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHH
VSWLAWGVAVLWIVGLLPAVRAELAGVAIHFGKSRVTALTLIEGSLSATVVMLLALWLSS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCCEEEEEEECCCHHHHHHHHHHHHHHH
TVERRLLDRTIVDLSMRKVAANATRAGLLLVGLLFALSAVGVDLTALSVLGGAVGVGLGF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHH
GLQKLASNYVSGFVILLERSLRIGDNVRVDGFEGRITDIKTRYTLIRAGNGRESIVPNET
HHHHHHHHHHHHHHHHHHHHHCCCCCEEECCCCCCEEEEEEEEEEEEECCCCCCCCCCHH
LITQRVENLSDADRKFNITTNITVGYDSDVSRVQAILCAAAAAQPRVLADPAPVAYLVNF
HHHHHHHHHHCCCCEEEEEEEEEECCCCCHHHHHHHHHHHHCCCCCEECCCCCCEEEEEC
APDGLEFSLNFWVSDPSAGTVNLRSAINIAILEGLRADGIDIPYPQRVVRLQADGPPPAG
CCCCCEEEEEEEEECCCCCEEEHHHHHHHHHHHCCCCCCCCCCCCHHEEEEECCCCCCCC
PLQVAHVAQASSPPPTA
CHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7610040; 9278503; 3042771 [H]