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The map label for this gene is smvA [H]

Identifier: 120610832

GI number: 120610832

Start: 2369831

End: 2371372

Strand: Direct

Name: smvA [H]

Synonym: Aave_2158

Alternate gene names: 120610832

Gene position: 2369831-2371372 (Clockwise)

Preceding gene: 120610829

Following gene: 120610838

Centisome position: 44.27

GC content: 72.63

Gene sequence:

>1542_bases
ATGTCCTTGCTTACTTCTCCTGCTTCGTCCCCGATGCAGCGGTGGCTCGTCCTGGCGGCGGTGATGCTGGCCTTCCTGCC
GGTGGTGATCGACATGACGATCCTCCACATCGCCGTCCCGTCGCTGACGCTGGCGTTGAGCGCATCGGGCACCCAGGTGC
TCTGGATCATCGACATCTATCCGCTGCTCATGGCGGGCCTGCTGGTGCCCATGGGAACGCTGGCGGACCGCACCGGTCAC
CGGCGGCTGCTGCTCGCCGGCCTGGCGGTCTTCGGCCTCGCATCGCTGCTGGCGGCATTCGCTCCCAGCCCGGCGATGCT
GATCGCGGCGCGCGTGCTGCTCGCGCTGGGCGGCTCGATGATCATGCCGTGCGTGCTCGGCATCATCCGCCGCACGTTCG
AGGATGAACGGGAGCGCGCCATGGCGCTGGGCCTCTGGGGCACCGTGGGCGCGGCGGGGGCTGCCGTGGGGCCGCTGGTC
GGCGGGGCGCTGCTGGAGCATTTCTGGTGGGGTGCCGCGTTCCTCATCAACGTGCCGGTGATGCTGGTCGTGTTCCCGGC
CGTGTTCCTGCTGCTGCCGCGGTCGGAGCGCACAGCGGCCGGCCGGTGGCCTGCCGGGCAGGCACTGCTGCTGATCGCCG
GCATGATCGCCGCGGTGTACGGCCTCAAGTCGGGATTCGGGGGCGGGCAGCCGCCGGCCGTGGCGGCATCGGCGCTGGCG
GCGGGAGCGGCCCTGCTGGCGGTGTTCGCGCGTCTGCAACTGCGCTCGCCGACGCCGATGCTGGACCTGTCGCTGTTCTC
GCGCCCTGCGATCCTTGCAGGCATCGCCATGGCGGTGGTCGCCACCGGCGCCCTGGCCGGGGTGGAGCTGACACTGGCGC
AGGAGCTGCAATACGTGCTGGGCAAGAGCCCGCTGCAGGCCGGCATCTTCATGGTGCCGATCATGGCCGCGGCAGCCGTG
GGCGGCCCCCTGGCCGGAACCCTGTCGAACCGCTTCGGACTGCGCCGGGTCGCCAGCCTGTCCCTGGCGGTGTCCGGCGC
GGCCCTGGCCTACCTGGCCCGGGCGGACTTCCACGAGGGCGGCGTGCCCGTGGCCGCGGCACTGGCGCTGCTCGGTCTGG
CGCTGAGCGTTGGGCTGACGGCGTCGTCCATCGCGATCATGGGGTCGGTCGAGGCGGACAGGGCCGGCGCGGCCGGGGCG
CTGGAGGCCACCGGCTACGAGCTGGGCAGCGGCCTGGGCATCACCCTGTTCGGGGTGTTCATGTCCGTCGTGTTCAGCCA
TGCGATCGCGCTGCCGCCGGATCTCGCGCCGCCGCTCGCCGTCCAGGCGGCCCGGTCGATCGGCGATGCCTACGTGGTCG
CGCAGCAACTGGCGGAGGGGCCGGCGGCCGCGCTGATCGGGGCCGGGCAGGCAGCCTTCTCGGTCGCCCATCGGGTGCTG
CTGAACACCTCCGCGGCGCTGATCGGCCTGCTGGCCGTGGCCGTGTTCATCCTGCTGGCCGGCTACCGTGGCGGGCCGGG
AGCTGCGGCGGGCGGGCACTGA

Upstream 100 bases:

>100_bases
CGTTTCGGACGGCATTGTGCCCCGGAATCCGAAGGCTTTCAGTTGAAATAAATACGTATGTATTTATATTCCGCGGCATT
GTGTTTCATCCGGGTGGTGC

Downstream 100 bases:

>100_bases
GGCGCCGCACCCGTCGGAGCACGTGGCCGCTGCGGAAAGGGTGGGCGCGGCGCTCCCGCGCTCAACCCGGCCGGCCGTCC
AGGCGCGGGCGGGAGAGGGC

Product: major facilitator superfamily transporter

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 513; Mature: 512

Protein sequence:

>513_residues
MSLLTSPASSPMQRWLVLAAVMLAFLPVVIDMTILHIAVPSLTLALSASGTQVLWIIDIYPLLMAGLLVPMGTLADRTGH
RRLLLAGLAVFGLASLLAAFAPSPAMLIAARVLLALGGSMIMPCVLGIIRRTFEDERERAMALGLWGTVGAAGAAVGPLV
GGALLEHFWWGAAFLINVPVMLVVFPAVFLLLPRSERTAAGRWPAGQALLLIAGMIAAVYGLKSGFGGGQPPAVAASALA
AGAALLAVFARLQLRSPTPMLDLSLFSRPAILAGIAMAVVATGALAGVELTLAQELQYVLGKSPLQAGIFMVPIMAAAAV
GGPLAGTLSNRFGLRRVASLSLAVSGAALAYLARADFHEGGVPVAAALALLGLALSVGLTASSIAIMGSVEADRAGAAGA
LEATGYELGSGLGITLFGVFMSVVFSHAIALPPDLAPPLAVQAARSIGDAYVVAQQLAEGPAAALIGAGQAAFSVAHRVL
LNTSAALIGLLAVAVFILLAGYRGGPGAAAGGH

Sequences:

>Translated_513_residues
MSLLTSPASSPMQRWLVLAAVMLAFLPVVIDMTILHIAVPSLTLALSASGTQVLWIIDIYPLLMAGLLVPMGTLADRTGH
RRLLLAGLAVFGLASLLAAFAPSPAMLIAARVLLALGGSMIMPCVLGIIRRTFEDERERAMALGLWGTVGAAGAAVGPLV
GGALLEHFWWGAAFLINVPVMLVVFPAVFLLLPRSERTAAGRWPAGQALLLIAGMIAAVYGLKSGFGGGQPPAVAASALA
AGAALLAVFARLQLRSPTPMLDLSLFSRPAILAGIAMAVVATGALAGVELTLAQELQYVLGKSPLQAGIFMVPIMAAAAV
GGPLAGTLSNRFGLRRVASLSLAVSGAALAYLARADFHEGGVPVAAALALLGLALSVGLTASSIAIMGSVEADRAGAAGA
LEATGYELGSGLGITLFGVFMSVVFSHAIALPPDLAPPLAVQAARSIGDAYVVAQQLAEGPAAALIGAGQAAFSVAHRVL
LNTSAALIGLLAVAVFILLAGYRGGPGAAAGGH
>Mature_512_residues
SLLTSPASSPMQRWLVLAAVMLAFLPVVIDMTILHIAVPSLTLALSASGTQVLWIIDIYPLLMAGLLVPMGTLADRTGHR
RLLLAGLAVFGLASLLAAFAPSPAMLIAARVLLALGGSMIMPCVLGIIRRTFEDERERAMALGLWGTVGAAGAAVGPLVG
GALLEHFWWGAAFLINVPVMLVVFPAVFLLLPRSERTAAGRWPAGQALLLIAGMIAAVYGLKSGFGGGQPPAVAASALAA
GAALLAVFARLQLRSPTPMLDLSLFSRPAILAGIAMAVVATGALAGVELTLAQELQYVLGKSPLQAGIFMVPIMAAAAVG
GPLAGTLSNRFGLRRVASLSLAVSGAALAYLARADFHEGGVPVAAALALLGLALSVGLTASSIAIMGSVEADRAGAAGAL
EATGYELGSGLGITLFGVFMSVVFSHAIALPPDLAPPLAVQAARSIGDAYVVAQQLAEGPAAALIGAGQAAFSVAHRVLL
NTSAALIGLLAVAVFILLAGYRGGPGAAAGGH

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily. TCR/tet family [H]

Homologues:

Organism=Escherichia coli, GI87081983, Length=415, Percent_Identity=27.4698795180723, Blast_Score=121, Evalue=1e-28,
Organism=Escherichia coli, GI1788710, Length=457, Percent_Identity=25.8205689277899, Blast_Score=102, Evalue=9e-23,
Organism=Escherichia coli, GI1788392, Length=437, Percent_Identity=27.2311212814645, Blast_Score=86, Evalue=8e-18,
Organism=Escherichia coli, GI1789042, Length=405, Percent_Identity=24.4444444444444, Blast_Score=85, Evalue=9e-18,
Organism=Escherichia coli, GI1790195, Length=393, Percent_Identity=25.1908396946565, Blast_Score=85, Evalue=1e-17,
Organism=Escherichia coli, GI1790146, Length=163, Percent_Identity=27.6073619631902, Blast_Score=63, Evalue=6e-11,
Organism=Saccharomyces cerevisiae, GI6322958, Length=514, Percent_Identity=23.5408560311284, Blast_Score=71, Evalue=4e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020846
- InterPro:   IPR011701
- InterPro:   IPR016196
- InterPro:   IPR001411 [H]

Pfam domain/function: PF07690 MFS_1 [H]

EC number: NA

Molecular weight: Translated: 51629; Mature: 51498

Theoretical pI: Translated: 9.69; Mature: 9.69

Prosite motif: PS50850 MFS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSLLTSPASSPMQRWLVLAAVMLAFLPVVIDMTILHIAVPSLTLALSASGTQVLWIIDIY
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEECCCCEEEEHHHHH
PLLMAGLLVPMGTLADRTGHRRLLLAGLAVFGLASLLAAFAPSPAMLIAARVLLALGGSM
HHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCHH
IMPCVLGIIRRTFEDERERAMALGLWGTVGAAGAAVGPLVGGALLEHFWWGAAFLINVPV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
MLVVFPAVFLLLPRSERTAAGRWPAGQALLLIAGMIAAVYGLKSGFGGGQPPAVAASALA
HHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHH
AGAALLAVFARLQLRSPTPMLDLSLFSRPAILAGIAMAVVATGALAGVELTLAQELQYVL
HHHHHHHHHHHHHCCCCCCCCHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GKSPLQAGIFMVPIMAAAAVGGPLAGTLSNRFGLRRVASLSLAVSGAALAYLARADFHEG
CCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
GVPVAAALALLGLALSVGLTASSIAIMGSVEADRAGAAGALEATGYELGSGLGITLFGVF
CCCHHHHHHHHHHHHHHCCCHHHHHEEECCCCCCCCCCCCCHHCCHHHCCCCHHHHHHHH
MSVVFSHAIALPPDLAPPLAVQAARSIGDAYVVAQQLAEGPAAALIGAGQAAFSVAHRVL
HHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHCCCHHHHHHHHHHH
LNTSAALIGLLAVAVFILLAGYRGGPGAAAGGH
HHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCC
>Mature Secondary Structure 
SLLTSPASSPMQRWLVLAAVMLAFLPVVIDMTILHIAVPSLTLALSASGTQVLWIIDIY
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEECCCCEEEEHHHHH
PLLMAGLLVPMGTLADRTGHRRLLLAGLAVFGLASLLAAFAPSPAMLIAARVLLALGGSM
HHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCHH
IMPCVLGIIRRTFEDERERAMALGLWGTVGAAGAAVGPLVGGALLEHFWWGAAFLINVPV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
MLVVFPAVFLLLPRSERTAAGRWPAGQALLLIAGMIAAVYGLKSGFGGGQPPAVAASALA
HHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHH
AGAALLAVFARLQLRSPTPMLDLSLFSRPAILAGIAMAVVATGALAGVELTLAQELQYVL
HHHHHHHHHHHHHCCCCCCCCHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GKSPLQAGIFMVPIMAAAAVGGPLAGTLSNRFGLRRVASLSLAVSGAALAYLARADFHEG
CCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
GVPVAAALALLGLALSVGLTASSIAIMGSVEADRAGAAGALEATGYELGSGLGITLFGVF
CCCHHHHHHHHHHHHHHCCCHHHHHEEECCCCCCCCCCCCCHHCCHHHCCCCHHHHHHHH
MSVVFSHAIALPPDLAPPLAVQAARSIGDAYVVAQQLAEGPAAALIGAGQAAFSVAHRVL
HHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHCCCHHHHHHHHHHH
LNTSAALIGLLAVAVFILLAGYRGGPGAAAGGH
HHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7926834; 11677609 [H]