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The map label for this gene is hflC [H]

Identifier: 120610119

GI number: 120610119

Start: 1573283

End: 1574182

Strand: Direct

Name: hflC [H]

Synonym: Aave_1432

Alternate gene names: 120610119

Gene position: 1573283-1574182 (Clockwise)

Preceding gene: 120610118

Following gene: 120610120

Centisome position: 29.39

GC content: 62.89

Gene sequence:

>900_bases
GTGAACAGAGTCGGATTCATCGTTTCCTCCCTGCTGGTAGTGCTCGCCCTGCTCAGCTCCGCGCTATTCGTCGTGGACCA
GCGCCAGTTCGGCGTGGTGTACCAGCTCGGGCAGATCAAGGAAGTCATCACCGAGCCGGGCCTCAACTTCAAGCTGCCCC
CGCCGTTCCAGAACGTGCGCTACATCGACAAGCGCCTGCTCACGCTGGACAGCACCGACACCGAGTCCATGCTGACCGCC
GAGAAGCAGCGCGTGGTGATCGACTGGTACGTGCGCTGGCGCATTTCCGATCCATCGGAGTACATCCGCAACGTGGGTCT
CGACGAGAACGCCGGCGCCCTGCAGCTCAACCGCGTCGTCCGCAATGCCTTCCAGGAAGAAGTCAACCGCCGTACGGTCA
GGGAATTGCTGTCCACCAAGCGCGATGCGCTCATGTCGGACGTGAAAAAGGAAGTCCTGGAGGTCGTCAAGGGCACCAAG
CCCTGGGGCGTGGACGTCGTCGATGTGCGCATCACCCGCGTCGATTACGTCGAGGCCATCACCGAGTCCGTCTATCGGCG
CATGGAAGCCGAGCGCAAGCGCGTGGCGAACGAACTCCGCTCCACCGGCGCGGCCGAGGGCGAGAAAATCCGCGCGGATG
CCGACAGGCAACGTGAGATCACCATCGCCAACGCCTACCGGGACGCCCAGAAGCTGAAGGGGGAGGGCGATGCCGAAGCC
GCGCGCATCTATGCGGATGCGTTCGGACGCGATGCCCAGTTCGCCCAGTTCTACCGGAGCCTCGAAGCCTACAAGTCGAG
CTTCAGCAAGAAGAGCGATGTGGTGGTGGTCGATCCGTCGTCCACCGAGTTCTTCAAGAACTTCCGCGGAAACGCGGCAT
CCCCCGCTCCTCGCAATTGA

Upstream 100 bases:

>100_bases
ACCTTCCAGTACCACCCAGGCATTCCCCATCGATTCCCGCGCGCGCGACACCAGCCGCACCCGGGACCGTGAAGCCCGCT
AGCCCGAGGGAGAGACAGTC

Downstream 100 bases:

>100_bases
GTCCATTCCGATCGGGAGGGCCGGCCGCTCCGCGCCGGCACCTCCAGCCGCGCAGGCTGGCACGCCTGTGCAGCATTCCG
CTCGTCCGCTGCGAGACGGC

Product: HflC protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 299; Mature: 299

Protein sequence:

>299_residues
MNRVGFIVSSLLVVLALLSSALFVVDQRQFGVVYQLGQIKEVITEPGLNFKLPPPFQNVRYIDKRLLTLDSTDTESMLTA
EKQRVVIDWYVRWRISDPSEYIRNVGLDENAGALQLNRVVRNAFQEEVNRRTVRELLSTKRDALMSDVKKEVLEVVKGTK
PWGVDVVDVRITRVDYVEAITESVYRRMEAERKRVANELRSTGAAEGEKIRADADRQREITIANAYRDAQKLKGEGDAEA
ARIYADAFGRDAQFAQFYRSLEAYKSSFSKKSDVVVVDPSSTEFFKNFRGNAASPAPRN

Sequences:

>Translated_299_residues
MNRVGFIVSSLLVVLALLSSALFVVDQRQFGVVYQLGQIKEVITEPGLNFKLPPPFQNVRYIDKRLLTLDSTDTESMLTA
EKQRVVIDWYVRWRISDPSEYIRNVGLDENAGALQLNRVVRNAFQEEVNRRTVRELLSTKRDALMSDVKKEVLEVVKGTK
PWGVDVVDVRITRVDYVEAITESVYRRMEAERKRVANELRSTGAAEGEKIRADADRQREITIANAYRDAQKLKGEGDAEA
ARIYADAFGRDAQFAQFYRSLEAYKSSFSKKSDVVVVDPSSTEFFKNFRGNAASPAPRN
>Mature_299_residues
MNRVGFIVSSLLVVLALLSSALFVVDQRQFGVVYQLGQIKEVITEPGLNFKLPPPFQNVRYIDKRLLTLDSTDTESMLTA
EKQRVVIDWYVRWRISDPSEYIRNVGLDENAGALQLNRVVRNAFQEEVNRRTVRELLSTKRDALMSDVKKEVLEVVKGTK
PWGVDVVDVRITRVDYVEAITESVYRRMEAERKRVANELRSTGAAEGEKIRADADRQREITIANAYRDAQKLKGEGDAEA
ARIYADAFGRDAQFAQFYRSLEAYKSSFSKKSDVVVVDPSSTEFFKNFRGNAASPAPRN

Specific function: HflC and HflK could encode or regulate a protease [H]

COG id: COG0330

COG function: function code O; Membrane protease subunits, stomatin/prohibitin homologs

Gene ontology:

Cell location: Membrane; Single-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the band 7/mec-2 family. HflC subfamily [H]

Homologues:

Organism=Escherichia coli, GI1790617, Length=309, Percent_Identity=33.6569579288026, Blast_Score=164, Evalue=7e-42,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001107
- InterPro:   IPR010200
- InterPro:   IPR001972 [H]

Pfam domain/function: PF01145 Band_7 [H]

EC number: 3.4.-.-

Molecular weight: Translated: 33967; Mature: 33967

Theoretical pI: Translated: 9.54; Mature: 9.54

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
1.3 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
1.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNRVGFIVSSLLVVLALLSSALFVVDQRQFGVVYQLGQIKEVITEPGLNFKLPPPFQNVR
CCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHH
YIDKRLLTLDSTDTESMLTAEKQRVVIDWYVRWRISDPSEYIRNVGLDENAGALQLNRVV
HHHHHHHHCCCCCHHHHHHHHHCEEEEEEEEEEEECCHHHHHHHCCCCCCCCHHHHHHHH
RNAFQEEVNRRTVRELLSTKRDALMSDVKKEVLEVVKGTKPWGVDVVDVRITRVDYVEAI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEEEHHHHHHHHH
TESVYRRMEAERKRVANELRSTGAAEGEKIRADADRQREITIANAYRDAQKLKGEGDAEA
HHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCEEEHHHHHHHHHHHCCCCCHHH
ARIYADAFGRDAQFAQFYRSLEAYKSSFSKKSDVVVVDPSSTEFFKNFRGNAASPAPRN
HHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCCEEEECCCCHHHHHHHCCCCCCCCCCC
>Mature Secondary Structure
MNRVGFIVSSLLVVLALLSSALFVVDQRQFGVVYQLGQIKEVITEPGLNFKLPPPFQNVR
CCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHH
YIDKRLLTLDSTDTESMLTAEKQRVVIDWYVRWRISDPSEYIRNVGLDENAGALQLNRVV
HHHHHHHHCCCCCHHHHHHHHHCEEEEEEEEEEEECCHHHHHHHCCCCCCCCHHHHHHHH
RNAFQEEVNRRTVRELLSTKRDALMSDVKKEVLEVVKGTKPWGVDVVDVRITRVDYVEAI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEEEHHHHHHHHH
TESVYRRMEAERKRVANELRSTGAAEGEKIRADADRQREITIANAYRDAQKLKGEGDAEA
HHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCEEEHHHHHHHHHHHCCCCCHHH
ARIYADAFGRDAQFAQFYRSLEAYKSSFSKKSDVVVVDPSSTEFFKNFRGNAASPAPRN
HHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCCEEEECCCCHHHHHHHCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Hydrolase; Acting on peptide bonds (Peptidases) [C]

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]