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The map label for this gene is dedA [H]

Identifier: 120609988

GI number: 120609988

Start: 1429142

End: 1429834

Strand: Direct

Name: dedA [H]

Synonym: Aave_1301

Alternate gene names: 120609988

Gene position: 1429142-1429834 (Clockwise)

Preceding gene: 120609985

Following gene: 120609990

Centisome position: 26.7

GC content: 65.51

Gene sequence:

>693_bases
GTGCCTCCGACCCCTTTTTTCCGCTCCGCCGCTCCTGAAGGATCCGCCTTGGAAGCCATCCAGTTCCTCATCGATTTCAT
CCTGCACGTGGACAAGCACATCGCGGCCTTCGTGGCCGCGTACGGCCCCTGGGTCTATGCGCTGCTCTTCGCCATCGTGT
TCGTGGAAACGGGCGTCGTCGTCATGCCCTTCCTGCCCGGCGACTCCCTGCTCTTCATCGTGGGCGCGCTGTGCGGCGCC
GGGCTGATGAGCTTTCCCATCGCCTGCGCCGTGCTGCTGGTGGCGGCCGTGCTCGGAGACCAGTGCAACTACACCATCGG
ACGGTATTTCGGGCCCAAGGTGTTCCAATGGCCGGATTCGCGGTGGTTCAACCGCCGGGCCTTCGAGCAGGCCCATGCGT
TCTACGAACGCTATGGCGGCATCACCATCGTGCTGGCGCGCTTCATGCCCTTCATCCGCACCTTCGCCCCGTTCGTGGCG
GGCGTGGCCGAAATGCACCGCGGCAAGTTCACCGCCTACAACGTGGGCGGTGCCATGCTGTGGGTGCTGGGCATCTGCAC
CGCGGGCTACTTCTTCGGCAACTTCCCCTGGGTGCAGGCGAACCTCGACAAGATCATCTGGGCGCTGATCCTGGTGCCGG
GCCTGATCGCGATCTTCGGCGCCTGGCGTGCGGGCCGCCGGCAGGCCGCATGA

Upstream 100 bases:

>100_bases
TGGCTCTGGGGTCATCGGGCGGCATTGTAGGCAGTGCGGTTAGAGTTACGCGCCGCGCCGCCGGGTGCCCGCCCCCTTCG
CGGGGCGAAAGCACCTGCCC

Downstream 100 bases:

>100_bases
CAGGGAAAGCGCGGCCGCGCATCGGCGCTACCCGCGCCGTCAGCGCAGCGTGCGCTCCAGCCACCGCAGCAGGTGGTGGT
TGACGGCTTCGGGGTTGTCC

Product: DedA protein (DSG-1 protein)

Products: NA

Alternate protein names: Protein DSG-1 [H]

Number of amino acids: Translated: 230; Mature: 229

Protein sequence:

>230_residues
MPPTPFFRSAAPEGSALEAIQFLIDFILHVDKHIAAFVAAYGPWVYALLFAIVFVETGVVVMPFLPGDSLLFIVGALCGA
GLMSFPIACAVLLVAAVLGDQCNYTIGRYFGPKVFQWPDSRWFNRRAFEQAHAFYERYGGITIVLARFMPFIRTFAPFVA
GVAEMHRGKFTAYNVGGAMLWVLGICTAGYFFGNFPWVQANLDKIIWALILVPGLIAIFGAWRAGRRQAA

Sequences:

>Translated_230_residues
MPPTPFFRSAAPEGSALEAIQFLIDFILHVDKHIAAFVAAYGPWVYALLFAIVFVETGVVVMPFLPGDSLLFIVGALCGA
GLMSFPIACAVLLVAAVLGDQCNYTIGRYFGPKVFQWPDSRWFNRRAFEQAHAFYERYGGITIVLARFMPFIRTFAPFVA
GVAEMHRGKFTAYNVGGAMLWVLGICTAGYFFGNFPWVQANLDKIIWALILVPGLIAIFGAWRAGRRQAA
>Mature_229_residues
PPTPFFRSAAPEGSALEAIQFLIDFILHVDKHIAAFVAAYGPWVYALLFAIVFVETGVVVMPFLPGDSLLFIVGALCGAG
LMSFPIACAVLLVAAVLGDQCNYTIGRYFGPKVFQWPDSRWFNRRAFEQAHAFYERYGGITIVLARFMPFIRTFAPFVAG
VAEMHRGKFTAYNVGGAMLWVLGICTAGYFFGNFPWVQANLDKIIWALILVPGLIAIFGAWRAGRRQAA

Specific function: Unknown

COG id: COG0586

COG function: function code S; Uncharacterized membrane-associated protein

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the dedA family [H]

Homologues:

Organism=Escherichia coli, GI1788656, Length=207, Percent_Identity=54.5893719806763, Blast_Score=224, Evalue=3e-60,
Organism=Escherichia coli, GI1789481, Length=156, Percent_Identity=35.2564102564103, Blast_Score=100, Evalue=1e-22,
Organism=Escherichia coli, GI1789384, Length=191, Percent_Identity=31.9371727748691, Blast_Score=98, Evalue=4e-22,
Organism=Escherichia coli, GI87082056, Length=150, Percent_Identity=28, Blast_Score=62, Evalue=4e-11,
Organism=Escherichia coli, GI1786252, Length=139, Percent_Identity=28.0575539568345, Blast_Score=60, Evalue=9e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR015414 [H]

Pfam domain/function: PF09335 SNARE_assoc [H]

EC number: NA

Molecular weight: Translated: 25372; Mature: 25241

Theoretical pI: Translated: 8.89; Mature: 8.89

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPPTPFFRSAAPEGSALEAIQFLIDFILHVDKHIAAFVAAYGPWVYALLFAIVFVETGVV
CCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCE
VMPFLPGDSLLFIVGALCGAGLMSFPIACAVLLVAAVLGDQCNYTIGRYFGPKVFQWPDS
EEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHCCCCCEECCCC
RWFNRRAFEQAHAFYERYGGITIVLARFMPFIRTFAPFVAGVAEMHRGKFTAYNVGGAML
HHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCHHHH
WVLGICTAGYFFGNFPWVQANLDKIIWALILVPGLIAIFGAWRAGRRQAA
HHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure 
PPTPFFRSAAPEGSALEAIQFLIDFILHVDKHIAAFVAAYGPWVYALLFAIVFVETGVV
CCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCE
VMPFLPGDSLLFIVGALCGAGLMSFPIACAVLLVAAVLGDQCNYTIGRYFGPKVFQWPDS
EEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHCCCCCEECCCC
RWFNRRAFEQAHAFYERYGGITIVLARFMPFIRTFAPFVAGVAEMHRGKFTAYNVGGAML
HHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCHHHH
WVLGICTAGYFFGNFPWVQANLDKIIWALILVPGLIAIFGAWRAGRRQAA
HHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]