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The map label for this gene is yfhR [C]

Identifier: 120609984

GI number: 120609984

Start: 1423880

End: 1424854

Strand: Reverse

Name: yfhR [C]

Synonym: Aave_1297

Alternate gene names: 120609984

Gene position: 1424854-1423880 (Counterclockwise)

Preceding gene: 120609986

Following gene: 120609982

Centisome position: 26.62

GC content: 69.95

Gene sequence:

>975_bases
ATGGTGCGTTTCTTGCAGCATGTCCTGCAGCCCGCACGGGCCCGACGAACTTTCCCACCCGACCGGAATCTGTTCATTTC
GATGAAACGCTGGCCCCTTTTCTCCTCCCTCGCGCTCGCCCTCGCAGTGACGGCGGGCTGCGCCACCCTCGACGCGAAGC
AGCGCGAATGGATCTTCCAGCCCAGCGACCGGGCCTGGGGAGGCGCGCAATCCACCGACGACATGCAGGACGTGTGGATC
GCGTTCGATTCGCGCGCCACGGGCAAGGCGGAGAAACTCCACGGGCTCTGGATGCCCTCGGACCGGGCCGATGCTCCCGT
GCTGCTGTACCTGCACGGCGCGCGCTGGAACGTTTCCGGCTCCGCCGGCAGGATCCGGCGCATGAACGACATGGGTTTCT
CGGTGCTGGCGGTGGACTACCGCGGCTTCGGGCGCAGCAGCCCGGCCCTGCCCTCCGAGGCGACGGCCCTGGAAGACGCC
CGGGCGGCCTGGGACTGGCTCGCCGCGCGGGAGCCCCGGGCGCCGCGCTACATCTTCGGCCATTCGCTGGGCGGGGCGAT
CGCCATCGACCTGGCCGCCATGGTGCCGGACGAACAGGGCACCATCGTGGAGGGAACGTTCACCAACATTCCCGAGGTGG
TGGCCACGTTCAAGTGGGGGTGGCTGCCGATCTCGGGCCTCATCACGCAGCGTTTCGAGTCGGTCCGCAAGGTGGCGCAC
ATCGGCTCGCCGCTGCTCGTGGTGCATGGCAGCGACGACAGCCTGATCCCGCCCACCCTGGGCAAGCGGCTGTATGAAGC
GGCCCAGGGGCCGAAGCGTTTCGTCCTGGTGGAGGGCGGCACCCACCACAGCACCAACAGCGTGGGCGAAGCGCAGTACC
GCGAGGCGCTGGCGGACCTGTTCCGCATCCCCGCCGGCCCGATGCCCGCGCGTGCGCCGGCGCAAAGGGCCACGGCCCCC
GGCTCCGCGGCCTGA

Upstream 100 bases:

>100_bases
CGTGACACCGCCGCCCCTCCTCCGGACGCGCGGCAAAAACCCGGATCAGCGGCACCCGGACAGGGTAATTCCAGGGTTCG
GCCCGTCAACCCGGGGAACC

Downstream 100 bases:

>100_bases
CCCGGGGCACGGCGCGGCTGCCCCCTTCCGGTCAGCCGCCTGCGACGGCAGCGGCCGCGGCCTGCCCCCGTGCCGCCAGG
ATCTCAGGCAGGTGCCCGCC

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 324; Mature: 324

Protein sequence:

>324_residues
MVRFLQHVLQPARARRTFPPDRNLFISMKRWPLFSSLALALAVTAGCATLDAKQREWIFQPSDRAWGGAQSTDDMQDVWI
AFDSRATGKAEKLHGLWMPSDRADAPVLLYLHGARWNVSGSAGRIRRMNDMGFSVLAVDYRGFGRSSPALPSEATALEDA
RAAWDWLAAREPRAPRYIFGHSLGGAIAIDLAAMVPDEQGTIVEGTFTNIPEVVATFKWGWLPISGLITQRFESVRKVAH
IGSPLLVVHGSDDSLIPPTLGKRLYEAAQGPKRFVLVEGGTHHSTNSVGEAQYREALADLFRIPAGPMPARAPAQRATAP
GSAA

Sequences:

>Translated_324_residues
MVRFLQHVLQPARARRTFPPDRNLFISMKRWPLFSSLALALAVTAGCATLDAKQREWIFQPSDRAWGGAQSTDDMQDVWI
AFDSRATGKAEKLHGLWMPSDRADAPVLLYLHGARWNVSGSAGRIRRMNDMGFSVLAVDYRGFGRSSPALPSEATALEDA
RAAWDWLAAREPRAPRYIFGHSLGGAIAIDLAAMVPDEQGTIVEGTFTNIPEVVATFKWGWLPISGLITQRFESVRKVAH
IGSPLLVVHGSDDSLIPPTLGKRLYEAAQGPKRFVLVEGGTHHSTNSVGEAQYREALADLFRIPAGPMPARAPAQRATAP
GSAA
>Mature_324_residues
MVRFLQHVLQPARARRTFPPDRNLFISMKRWPLFSSLALALAVTAGCATLDAKQREWIFQPSDRAWGGAQSTDDMQDVWI
AFDSRATGKAEKLHGLWMPSDRADAPVLLYLHGARWNVSGSAGRIRRMNDMGFSVLAVDYRGFGRSSPALPSEATALEDA
RAAWDWLAAREPRAPRYIFGHSLGGAIAIDLAAMVPDEQGTIVEGTFTNIPEVVATFKWGWLPISGLITQRFESVRKVAH
IGSPLLVVHGSDDSLIPPTLGKRLYEAAQGPKRFVLVEGGTHHSTNSVGEAQYREALADLFRIPAGPMPARAPAQRATAP
GSAA

Specific function: Unknown

COG id: COG1073

COG function: function code R; Hydrolases of the alpha/beta superfamily

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: To S.pombe bem46 and yeast YNL320w [H]

Homologues:

Organism=Homo sapiens, GI32528310, Length=193, Percent_Identity=34.7150259067358, Blast_Score=99, Evalue=4e-21,
Organism=Homo sapiens, GI32451492, Length=193, Percent_Identity=34.7150259067358, Blast_Score=99, Evalue=4e-21,
Organism=Homo sapiens, GI109689718, Length=191, Percent_Identity=34.5549738219895, Blast_Score=97, Evalue=2e-20,
Organism=Homo sapiens, GI24308097, Length=191, Percent_Identity=34.5549738219895, Blast_Score=97, Evalue=3e-20,
Organism=Homo sapiens, GI49355781, Length=190, Percent_Identity=33.1578947368421, Blast_Score=86, Evalue=5e-17,
Organism=Homo sapiens, GI71051600, Length=259, Percent_Identity=26.2548262548263, Blast_Score=75, Evalue=1e-13,
Organism=Homo sapiens, GI71051602, Length=256, Percent_Identity=26.5625, Blast_Score=75, Evalue=1e-13,
Organism=Escherichia coli, GI226510965, Length=285, Percent_Identity=28.7719298245614, Blast_Score=92, Evalue=5e-20,
Organism=Caenorhabditis elegans, GI17566318, Length=192, Percent_Identity=26.5625, Blast_Score=87, Evalue=1e-17,
Organism=Caenorhabditis elegans, GI71985392, Length=183, Percent_Identity=32.2404371584699, Blast_Score=82, Evalue=4e-16,
Organism=Caenorhabditis elegans, GI71985387, Length=175, Percent_Identity=29.7142857142857, Blast_Score=77, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI17532877, Length=157, Percent_Identity=29.2993630573248, Blast_Score=70, Evalue=2e-12,
Organism=Drosophila melanogaster, GI17137566, Length=209, Percent_Identity=33.0143540669856, Blast_Score=88, Evalue=7e-18,
Organism=Drosophila melanogaster, GI24655464, Length=182, Percent_Identity=31.3186813186813, Blast_Score=81, Evalue=8e-16,
Organism=Drosophila melanogaster, GI24655467, Length=182, Percent_Identity=31.3186813186813, Blast_Score=81, Evalue=9e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002925 [H]

Pfam domain/function: PF01738 DLH [H]

EC number: NA

Molecular weight: Translated: 35361; Mature: 35361

Theoretical pI: Translated: 9.94; Mature: 9.94

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVRFLQHVLQPARARRTFPPDRNLFISMKRWPLFSSLALALAVTAGCATLDAKQREWIFQ
CHHHHHHHHHHHHHHCCCCCCCCEEEEEECCCCHHHHHHHHHHHHCHHHCCCCCCCCEEC
PSDRAWGGAQSTDDMQDVWIAFDSRATGKAEKLHGLWMPSDRADAPVLLYLHGARWNVSG
CCCCCCCCCCCCCCHHEEEEEECCCCCCCHHHHEEEECCCCCCCCCEEEEEECCEEECCC
SAGRIRRMNDMGFSVLAVDYRGFGRSSPALPSEATALEDARAAWDWLAAREPRAPRYIFG
CCCCEEEECCCCEEEEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCEEEEC
HSLGGAIAIDLAAMVPDEQGTIVEGTFTNIPEVVATFKWGWLPISGLITQRFESVRKVAH
CCCCCEEEEEHHHHCCCCCCCEEECCCCCCHHHHHHHCCCCEEHHHHHHHHHHHHHHHHH
IGSPLLVVHGSDDSLIPPTLGKRLYEAAQGPKRFVLVEGGTHHSTNSVGEAQYREALADL
CCCCEEEEECCCCCCCCHHHHHHHHHHHCCCCEEEEEECCCCCCCCCCHHHHHHHHHHHH
FRIPAGPMPARAPAQRATAPGSAA
HHCCCCCCCCCCCHHHCCCCCCCC
>Mature Secondary Structure
MVRFLQHVLQPARARRTFPPDRNLFISMKRWPLFSSLALALAVTAGCATLDAKQREWIFQ
CHHHHHHHHHHHHHHCCCCCCCCEEEEEECCCCHHHHHHHHHHHHCHHHCCCCCCCCEEC
PSDRAWGGAQSTDDMQDVWIAFDSRATGKAEKLHGLWMPSDRADAPVLLYLHGARWNVSG
CCCCCCCCCCCCCCHHEEEEEECCCCCCCHHHHEEEECCCCCCCCCEEEEEECCEEECCC
SAGRIRRMNDMGFSVLAVDYRGFGRSSPALPSEATALEDARAAWDWLAAREPRAPRYIFG
CCCCEEEECCCCEEEEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCEEEEC
HSLGGAIAIDLAAMVPDEQGTIVEGTFTNIPEVVATFKWGWLPISGLITQRFESVRKVAH
CCCCCEEEEEHHHHCCCCCCCEEECCCCCCHHHHHHHCCCCEEHHHHHHHHHHHHHHHHH
IGSPLLVVHGSDDSLIPPTLGKRLYEAAQGPKRFVLVEGGTHHSTNSVGEAQYREALADL
CCCCEEEEECCCCCCCCHHHHHHHHHHHCCCCEEEEEECCCCCCCCCCHHHHHHHHHHHH
FRIPAGPMPARAPAQRATAPGSAA
HHCCCCCCCCCCCHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036 [H]