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The map label for this gene is add [H]

Identifier: 120609828

GI number: 120609828

Start: 1250888

End: 1252015

Strand: Direct

Name: add [H]

Synonym: Aave_1138

Alternate gene names: 120609828

Gene position: 1250888-1252015 (Clockwise)

Preceding gene: 120609827

Following gene: 120609829

Centisome position: 23.37

GC content: 69.33

Gene sequence:

>1128_bases
ATGCTCTGCGCTGCGCGCATCCGTGCCGCCCTTCCTCCCCAAAGGCTCCCCATGACCGATTCCCCTACCGCACCCCCGCC
GCATTTCGGCGGCATCGCCACGGAGCGCCTGCCCGACCTGCTGCGCGCCATGCCCAAGGCGGAGCTGCACATGCACATCG
AGGGCTCGCTCGAGCCCGAACTGATCTTCGCGCTCGCCGAGCGCAACGGCGTGGCGCTGCCCTATGCCGACGTGGAGTCG
CTGCGCGCCGCCTACGCCTTCACCAACCTGCAGAGCTTCCTGGACATCTACTACGCCGGTGCGAGCGTGCTGCTGCACGA
GCAGGATTTCTACGACATGGCCTGGGCCTACCTGCAGCGCGCGGCCGCCGACCACATCGTGCACACCGAGATGTTCTTCG
ATCCACAGACGCACACCGCGCGCGGCGTCGGCATCGACGTGGTGATCCACGGCCTGCACCGCGCCTGCGAGGACGCCCGG
ACGCAACTGGGCGTGAGCGCCTCGCTGATCCTGTGCTTCCTGCGCCACCTGAGCGAAGAAGACGCCTTCGAGACGCTGGA
GCAGGCGCTGCCCTACCGCGACCGCTTCATCGGCGTCGGCCTGGATTCGAGCGAGGTGGGCCACCCGCCGGAGAAGTTCG
CCCGCGTGTTCGCGCGCTGCGGCGAACTGGGCCTGCACCGCGTCGCGCACGCGGGCGAGGAGGGGCCGCCGGCCTATATC
TGGAGCGCGCTCGACGTGCTGCGCGCCGAGCGCATCGACCACGGCGTGCAGGCCGTGCACGACCCGGCCCTGATGCGCCG
GCTGGCCGCCGAGCGCGTGGCGCTCACCGTCTGCCCGCTGTCCAACGAGAAGCTGTGCGTCTTCCCCGACCTGGCGGACC
ACAACATCCAGGCCCTGCTGGACGCGGGCCTGGCGGCCACGGTGAACTCGGACGACCCTGCCTATTTCGGGGGCTACCTG
AACACGAATTTCGTGCGCCTGTTCGAGGCCGTTCCCACGCTGACGGCGGCGCATGCCTACCAGCTCGCATCCAACAGTTT
CGATGCGAGCTTCGTTCCGGACGAGGACAAGCAGGCCTGGCGGCGCCAGTTGCAGGCCTGCTTCGCGGGTTTCGCAGCCC
GGCGCTGA

Upstream 100 bases:

>100_bases
ATGGCGGGCCAGAGCTGGAACGCGGCCACCTTCCTGCTGGCCCGGCGCGCGCTGCAGGGGCTCGATTCCGCCTGGTAGCC
CGCGCCCCCCGGGGCGCCTT

Downstream 100 bases:

>100_bases
ACGGGTCCGGAATCCCGGGTTTTCCACGGGTCATTGCGGATCGACGGCGGGGCAGTGGTGGCGCGAGAATTCCCCTGAGA
GCCCAACCGCTCCAGGGCCG

Product: adenosine deaminase

Products: NA

Alternate protein names: Adenosine aminohydrolase [H]

Number of amino acids: Translated: 375; Mature: 375

Protein sequence:

>375_residues
MLCAARIRAALPPQRLPMTDSPTAPPPHFGGIATERLPDLLRAMPKAELHMHIEGSLEPELIFALAERNGVALPYADVES
LRAAYAFTNLQSFLDIYYAGASVLLHEQDFYDMAWAYLQRAAADHIVHTEMFFDPQTHTARGVGIDVVIHGLHRACEDAR
TQLGVSASLILCFLRHLSEEDAFETLEQALPYRDRFIGVGLDSSEVGHPPEKFARVFARCGELGLHRVAHAGEEGPPAYI
WSALDVLRAERIDHGVQAVHDPALMRRLAAERVALTVCPLSNEKLCVFPDLADHNIQALLDAGLAATVNSDDPAYFGGYL
NTNFVRLFEAVPTLTAAHAYQLASNSFDASFVPDEDKQAWRRQLQACFAGFAARR

Sequences:

>Translated_375_residues
MLCAARIRAALPPQRLPMTDSPTAPPPHFGGIATERLPDLLRAMPKAELHMHIEGSLEPELIFALAERNGVALPYADVES
LRAAYAFTNLQSFLDIYYAGASVLLHEQDFYDMAWAYLQRAAADHIVHTEMFFDPQTHTARGVGIDVVIHGLHRACEDAR
TQLGVSASLILCFLRHLSEEDAFETLEQALPYRDRFIGVGLDSSEVGHPPEKFARVFARCGELGLHRVAHAGEEGPPAYI
WSALDVLRAERIDHGVQAVHDPALMRRLAAERVALTVCPLSNEKLCVFPDLADHNIQALLDAGLAATVNSDDPAYFGGYL
NTNFVRLFEAVPTLTAAHAYQLASNSFDASFVPDEDKQAWRRQLQACFAGFAARR
>Mature_375_residues
MLCAARIRAALPPQRLPMTDSPTAPPPHFGGIATERLPDLLRAMPKAELHMHIEGSLEPELIFALAERNGVALPYADVES
LRAAYAFTNLQSFLDIYYAGASVLLHEQDFYDMAWAYLQRAAADHIVHTEMFFDPQTHTARGVGIDVVIHGLHRACEDAR
TQLGVSASLILCFLRHLSEEDAFETLEQALPYRDRFIGVGLDSSEVGHPPEKFARVFARCGELGLHRVAHAGEEGPPAYI
WSALDVLRAERIDHGVQAVHDPALMRRLAAERVALTVCPLSNEKLCVFPDLADHNIQALLDAGLAATVNSDDPAYFGGYL
NTNFVRLFEAVPTLTAAHAYQLASNSFDASFVPDEDKQAWRRQLQACFAGFAARR

Specific function: Unknown

COG id: COG1816

COG function: function code F; Adenosine deaminase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the adenosine and AMP deaminases family [H]

Homologues:

Organism=Homo sapiens, GI47078295, Length=340, Percent_Identity=25.2941176470588, Blast_Score=112, Evalue=5e-25,
Organism=Escherichia coli, GI1787910, Length=332, Percent_Identity=29.8192771084337, Blast_Score=137, Evalue=1e-33,
Organism=Caenorhabditis elegans, GI32565969, Length=339, Percent_Identity=23.0088495575221, Blast_Score=76, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI17538512, Length=339, Percent_Identity=23.0088495575221, Blast_Score=76, Evalue=3e-14,
Organism=Saccharomyces cerevisiae, GI6324188, Length=329, Percent_Identity=41.3373860182371, Blast_Score=280, Evalue=3e-76,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001365
- InterPro:   IPR006330 [H]

Pfam domain/function: PF00962 A_deaminase [H]

EC number: =3.5.4.4 [H]

Molecular weight: Translated: 41379; Mature: 41379

Theoretical pI: Translated: 5.50; Mature: 5.50

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLCAARIRAALPPQRLPMTDSPTAPPPHFGGIATERLPDLLRAMPKAELHMHIEGSLEPE
CCCHHHHHHCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCEEEEECCCCCHH
LIFALAERNGVALPYADVESLRAAYAFTNLQSFLDIYYAGASVLLHEQDFYDMAWAYLQR
HEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEECCHHHHHHHHHHHH
AAADHIVHTEMFFDPQTHTARGVGIDVVIHGLHRACEDARTQLGVSASLILCFLRHLSEE
HHHHHHEEHHHEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCC
DAFETLEQALPYRDRFIGVGLDSSEVGHPPEKFARVFARCGELGLHRVAHAGEEGPPAYI
HHHHHHHHHCCCCCCEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHH
WSALDVLRAERIDHGVQAVHDPALMRRLAAERVALTVCPLSNEKLCVFPDLADHNIQALL
HHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHEEEEECCCCCCEEEECCCCCCHHHHHH
DAGLAATVNSDDPAYFGGYLNTNFVRLFEAVPTLTAAHAYQLASNSFDASFVPDEDKQAW
HCCCEEEECCCCCCEECCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHH
RRQLQACFAGFAARR
HHHHHHHHHHHHCCC
>Mature Secondary Structure
MLCAARIRAALPPQRLPMTDSPTAPPPHFGGIATERLPDLLRAMPKAELHMHIEGSLEPE
CCCHHHHHHCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCEEEEECCCCCHH
LIFALAERNGVALPYADVESLRAAYAFTNLQSFLDIYYAGASVLLHEQDFYDMAWAYLQR
HEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEECCHHHHHHHHHHHH
AAADHIVHTEMFFDPQTHTARGVGIDVVIHGLHRACEDARTQLGVSASLILCFLRHLSEE
HHHHHHEEHHHEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCC
DAFETLEQALPYRDRFIGVGLDSSEVGHPPEKFARVFARCGELGLHRVAHAGEEGPPAYI
HHHHHHHHHCCCCCCEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHH
WSALDVLRAERIDHGVQAVHDPALMRRLAAERVALTVCPLSNEKLCVFPDLADHNIQALL
HHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHEEEEECCCCCCEEEECCCCCCHHHHHH
DAGLAATVNSDDPAYFGGYLNTNFVRLFEAVPTLTAAHAYQLASNSFDASFVPDEDKQAW
HCCCEEEECCCCCCEECCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHH
RRQLQACFAGFAARR
HHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA