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The map label for this gene is dacC [H]

Identifier: 120609035

GI number: 120609035

Start: 363903

End: 365084

Strand: Direct

Name: dacC [H]

Synonym: Aave_0332

Alternate gene names: 120609035

Gene position: 363903-365084 (Clockwise)

Preceding gene: 120609034

Following gene: 120609036

Centisome position: 6.8

GC content: 66.84

Gene sequence:

>1182_bases
ATGCATGCCTCCCTGAAGTCCTTCCTGCCCCTGCTGCGCTCCTTCGCCATGGCCGCCGCGCTCGCGCCTGCCGCACTCTG
GGCGCAGGTGCAGGCGCCCCAGCCGCCCGAGATCGCCGCGCGCAACTACCTGCTGCTGGACGTGACCGCCGGGCAGGTAC
TGGCCGCCAAGGACATCGACGCCCCCGTGGAGCAGGCGTCCTTGACCAAGCTCATGACGGGCTACCTGGTGTTCGATGCG
CTGCGCGCCAAGAAGATCACGCTGGAGCAGAGGCTCCCCGTGAGCGAGCGCGCCTGGAAGATGCCGGGCTCGCGCATGTT
CATTGATCCCAAGATGCAGGTGCCGGTGGAAGACCTCATCAAGGGCATGATCGTGCAGTCGGGCAACGACGCCACCATGG
CCCTCGCCGAGGGCGTGGGCGGCACGGCCGAGAACTTCGTCAAGCTCATGAACGACCAGGCCAGGGCCCTGGGCATGAAG
AACACGGCCTACAAGAATCCCGAGGGCCTCACCGAGCCCGGCCACACGACCACGGCGCGCGACCTGAGCGTGCTCGCCAC
GCGGCTCATGAAGGATTTCCCGGAGTACATGCATTACTACTCCACCAAGCATTACGCCTACCCGGGCACGCCGCCGTCCA
ACGGCACCAACCGCAATGCGCTGCTGTTCCGCGACCCGACCGTCGATGGCCTCAAGACCGGCCACACCGCGGCAGCGGGC
TATTGCCTGGTCGCCACGTCCAAGCGCGATTTCCCGAACATCGGCCAGCGCCGGCTGCTGTCCATCGTGCTCGGTGCAGC
CAGCGAAAGCGCCCGCGCCAACGAAAGCCAGAAGCTCCTGAACTGGGGCTACACCGCCTACGATGCCGTCAAGCTGTTCG
ATGCAGGCCAGCCTGCCGCCACCCCGGCGCTCTGGAAAGGCGTGCAGAACACCATCAAGATCGGGCGCCCCGATCCCATC
GTCGTCACCGTGCCGTCGGGTTCGGCCGGCAAGATCACGACCCAGGTCGTCCGGCAGGACCCGCTGGTCGCACCGCTGAC
GAAGGGCCAATCCATCGGCACGCTCAAGGTGTCGCTGGGCGAACAGCAGATCGCCGAGGTGCCCCTGGTGGCGCTCGAGA
CCGTCGATCAGGCGGGCATCTTCGGCCGTGCCTGGGATGCCATCCGGCTCTGGATCAAGTGA

Upstream 100 bases:

>100_bases
ACCTGACTTCCCAGGCCTGAGGGGCAGGCCGCCGGCTGCCTGCCGCCCGCCTCCTCTTTCTTTCTATCCCCCAGTTCCCC
TTCTTCCCGGACCGTTCCGA

Downstream 100 bases:

>100_bases
TGCGCGCTGCGCGTGGCGGGAGGCCGGCGGCGCCGGTCCTTGCCTCGCCCCGGGCAAACTGATACATTAGAAGGCTTTTC
GGAATTTCCGAAGGGAATCA

Product: penicillin-binding protein 6

Products: NA

Alternate protein names: DD-carboxypeptidase; DD-peptidase; Penicillin-binding protein 6; PBP-6 [H]

Number of amino acids: Translated: 393; Mature: 393

Protein sequence:

>393_residues
MHASLKSFLPLLRSFAMAAALAPAALWAQVQAPQPPEIAARNYLLLDVTAGQVLAAKDIDAPVEQASLTKLMTGYLVFDA
LRAKKITLEQRLPVSERAWKMPGSRMFIDPKMQVPVEDLIKGMIVQSGNDATMALAEGVGGTAENFVKLMNDQARALGMK
NTAYKNPEGLTEPGHTTTARDLSVLATRLMKDFPEYMHYYSTKHYAYPGTPPSNGTNRNALLFRDPTVDGLKTGHTAAAG
YCLVATSKRDFPNIGQRRLLSIVLGAASESARANESQKLLNWGYTAYDAVKLFDAGQPAATPALWKGVQNTIKIGRPDPI
VVTVPSGSAGKITTQVVRQDPLVAPLTKGQSIGTLKVSLGEQQIAEVPLVALETVDQAGIFGRAWDAIRLWIK

Sequences:

>Translated_393_residues
MHASLKSFLPLLRSFAMAAALAPAALWAQVQAPQPPEIAARNYLLLDVTAGQVLAAKDIDAPVEQASLTKLMTGYLVFDA
LRAKKITLEQRLPVSERAWKMPGSRMFIDPKMQVPVEDLIKGMIVQSGNDATMALAEGVGGTAENFVKLMNDQARALGMK
NTAYKNPEGLTEPGHTTTARDLSVLATRLMKDFPEYMHYYSTKHYAYPGTPPSNGTNRNALLFRDPTVDGLKTGHTAAAG
YCLVATSKRDFPNIGQRRLLSIVLGAASESARANESQKLLNWGYTAYDAVKLFDAGQPAATPALWKGVQNTIKIGRPDPI
VVTVPSGSAGKITTQVVRQDPLVAPLTKGQSIGTLKVSLGEQQIAEVPLVALETVDQAGIFGRAWDAIRLWIK
>Mature_393_residues
MHASLKSFLPLLRSFAMAAALAPAALWAQVQAPQPPEIAARNYLLLDVTAGQVLAAKDIDAPVEQASLTKLMTGYLVFDA
LRAKKITLEQRLPVSERAWKMPGSRMFIDPKMQVPVEDLIKGMIVQSGNDATMALAEGVGGTAENFVKLMNDQARALGMK
NTAYKNPEGLTEPGHTTTARDLSVLATRLMKDFPEYMHYYSTKHYAYPGTPPSNGTNRNALLFRDPTVDGLKTGHTAAAG
YCLVATSKRDFPNIGQRRLLSIVLGAASESARANESQKLLNWGYTAYDAVKLFDAGQPAATPALWKGVQNTIKIGRPDPI
VVTVPSGSAGKITTQVVRQDPLVAPLTKGQSIGTLKVSLGEQQIAEVPLVALETVDQAGIFGRAWDAIRLWIK

Specific function: Removes C-terminal D-alanyl residues from sugar-peptide cell wall precursors [H]

COG id: COG1686

COG function: function code M; D-alanyl-D-alanine carboxypeptidase

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein. Note=N-terminal lies in the periplasmic space [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase S11 family [H]

Homologues:

Organism=Escherichia coli, GI1787062, Length=398, Percent_Identity=38.4422110552764, Blast_Score=262, Evalue=3e-71,
Organism=Escherichia coli, GI1786851, Length=396, Percent_Identity=34.5959595959596, Blast_Score=238, Evalue=3e-64,
Organism=Escherichia coli, GI87082022, Length=363, Percent_Identity=36.6391184573003, Blast_Score=235, Evalue=4e-63,
Organism=Escherichia coli, GI87082054, Length=258, Percent_Identity=28.6821705426357, Blast_Score=88, Evalue=8e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012338
- InterPro:   IPR015956
- InterPro:   IPR018044
- InterPro:   IPR012907
- InterPro:   IPR001967 [H]

Pfam domain/function: PF07943 PBP5_C; PF00768 Peptidase_S11 [H]

EC number: =3.4.16.4 [H]

Molecular weight: Translated: 42436; Mature: 42436

Theoretical pI: Translated: 9.83; Mature: 9.83

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHASLKSFLPLLRSFAMAAALAPAALWAQVQAPQPPEIAARNYLLLDVTAGQVLAAKDID
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHCCEEEEEECCCCEEEECCCC
APVEQASLTKLMTGYLVFDALRAKKITLEQRLPVSERAWKMPGSRMFIDPKMQVPVEDLI
CCHHHHHHHHHHHHHHHHHHHHHHHEEHHHCCCCHHHHHCCCCCEEEECCCCCCCHHHHH
KGMIVQSGNDATMALAEGVGGTAENFVKLMNDQARALGMKNTAYKNPEGLTEPGHTTTAR
HHHEEECCCCCEEEEHHCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCHHH
DLSVLATRLMKDFPEYMHYYSTKHYAYPGTPPSNGTNRNALLFRDPTVDGLKTGHTAAAG
HHHHHHHHHHHHHHHHHHHHCCCCEECCCCCCCCCCCCCEEEEECCCCCCCCCCCCHHCC
YCLVATSKRDFPNIGQRRLLSIVLGAASESARANESQKLLNWGYTAYDAVKLFDAGQPAA
EEEEEECCCCCCCHHHHHHHHHHHHCCCCCCCCCCHHHHHHCCCHHHHHHHEECCCCCCC
TPALWKGVQNTIKIGRPDPIVVTVPSGSAGKITTQVVRQDPLVAPLTKGQSIGTLKVSLG
CHHHHHCCHHHEECCCCCCEEEEECCCCCCCHHHHHHHCCCCEEECCCCCCCEEEEEECC
EQQIAEVPLVALETVDQAGIFGRAWDAIRLWIK
HHHHHHCCHHHHHHHHHCCCCHHCCHHEEEECC
>Mature Secondary Structure
MHASLKSFLPLLRSFAMAAALAPAALWAQVQAPQPPEIAARNYLLLDVTAGQVLAAKDID
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHCCEEEEEECCCCEEEECCCC
APVEQASLTKLMTGYLVFDALRAKKITLEQRLPVSERAWKMPGSRMFIDPKMQVPVEDLI
CCHHHHHHHHHHHHHHHHHHHHHHHEEHHHCCCCHHHHHCCCCCEEEECCCCCCCHHHHH
KGMIVQSGNDATMALAEGVGGTAENFVKLMNDQARALGMKNTAYKNPEGLTEPGHTTTAR
HHHEEECCCCCEEEEHHCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCHHH
DLSVLATRLMKDFPEYMHYYSTKHYAYPGTPPSNGTNRNALLFRDPTVDGLKTGHTAAAG
HHHHHHHHHHHHHHHHHHHHCCCCEECCCCCCCCCCCCCEEEEECCCCCCCCCCCCHHCC
YCLVATSKRDFPNIGQRRLLSIVLGAASESARANESQKLLNWGYTAYDAVKLFDAGQPAA
EEEEEECCCCCCCHHHHHHHHHHHHCCCCCCCCCCHHHHHHCCCHHHHHHHEECCCCCCC
TPALWKGVQNTIKIGRPDPIVVTVPSGSAGKITTQVVRQDPLVAPLTKGQSIGTLKVSLG
CHHHHHCCHHHEECCCCCCEEEEECCCCCCCHHHHHHHCCCCEEECCCCCCCEEEEEECC
EQQIAEVPLVALETVDQAGIFGRAWDAIRLWIK
HHHHHHCCHHHHHHHHHCCCCHHCCHHEEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 3279397; 8905232; 9278503; 7042389 [H]