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The map label for this gene is plcN [H]

Identifier: 120608924

GI number: 120608924

Start: 242595

End: 244907

Strand: Direct

Name: plcN [H]

Synonym: Aave_0219

Alternate gene names: 120608924

Gene position: 242595-244907 (Clockwise)

Preceding gene: 120608923

Following gene: 120608926

Centisome position: 4.53

GC content: 69.87

Gene sequence:

>2313_bases
ATGACCCGTGCCTTTTCGTACAACAAACACTCCTCCAACATGACCGTCGATTCCTCCAAACGCAAGTTCCTCTCCGGCGT
GCTCGGCACCGGAGCGGCCGCGGCCACGCTCACGGCCTTCCCGCCCGCCATCCGGCGCGCGCTCGCCATCGAGGCGAACA
ACGCCACCGGCACCATCCAGGACGTGCAGCACGTGGTTCTGCTGATGATGGAAAACCGCTCGTTCGACAGCTATTTCGGC
ACCTTCAAGGGCGTGCGCGGTTTCGGCGACCGCTTCGCCGTGCCCACGCCGAATGGCCGCAATGTCTTCTACCAGACCTA
CACCAAGACCACGCCCGCCAGCACCTACGTGCCCTTCCGGCTGGACGAGGCCCAGGGCAACGCCCAGCGCGCCGGCAGCA
CGCCGCACACCTGGGTGGATTCGCAGGCGGCCTGGGACCATGGCCGCATGTCGCGCTGGCCCGATGCGAAACTGCCCCTC
TCGATGGGCTACTACGAGACGGCCGAGGTCTCGTTCCAGCGCGCCCTGGCCGATGCCTTCACGCTGTGCGACCACTACCA
CTGCGGCATGCACACGGGCACCATCGCCAACCGGCTCTTCTACTGGACGGGCACCAACGGCCCCAACGGCATCAGCCCGC
TCGACGGCTCCCGCGTGCGCGTGGCGGGCCTGAACAACCAGTTCAACGGAGGCAACGACGTCGGCGCCTCCACCGAAGGC
TGGACGTGGACGACCTATGCCGACCGCCTGGAGAAGGCCGGCGTGTCGTGGAAGGTCTACCAGAGCCTGATCGACAACTT
CGGCTGCAACGAGATGATGGGATTTCGCCACTGGCGCGCCGAGATCGAGAAGATGCCCGCGGACCGCAAGCCGCTCTACG
TGGCCAAGACCGACATCACGCAGCCGCAGGACCTGGCCGGCCCCACCTACGACCCGGCCATCGACGACGCCCTGAGCCCG
CTCGCCAAGGGCTTCGGCAACACCATGCCGCAGGGCTTCCTGGAGACCTTCCGCGAGGACATCCGCCAGGGCCGGCTGCC
GGCGGTGTCGTGGATCATCGCGCCCTCGGTCTATAGCGAGCACCCCGGCCCGTCGAGCCCCGCGCAGGGTGGCTGGTACG
TGCAGGAAGTGCTGGACGCGCTCACCGCCAATCCGGAGGTGTGGAGCAAGACGGTGCTGCTCATCAACTACGACGAGAAC
GACGGCTTCTTCGACCACCTGCCGTCGCCCGCCGTGCCTTCGCGCAACGCCGACGGCAGCCTGGCCGGCGCCTGCACGCT
GTCCGCCGCCGACGTGGCCGTGGAATACCACGACTTCCAGCCCGCCACCTCCAGCCAGCCTGCGGCCGACGGCAAGCCCT
ACGGCCCCGGCCCGCGCGTGCCGATGTGGGTCGTCTCGCCCTGGAGCCGCGGCGGCTGGGTGAATTCGCAGGTGTTCGAC
CACACCTCCACGCTCATGTTCCTGGAGAAGCGCTTCGGCGTGGCCGAGCCGCAGATCAGCGCCTACCGCCGCGCGGTCTG
CGGCGACCTGACCAGCTGCTTCAACTTCGTCAACCCGAACACCGAGGCCCTGCCCACGCTGGCCGGCCGCACCAGCAAGA
CGGCCGTGGACGCGCGCATCGCCGCGCAGGTGCGTGCCGCCAAACTGCCCCAACCCGCCGCGGCCACGGATGCGGCCCTG
CCGGTGCAGGCGCCGGGCGTGCGGCCTTCGCGCGCGCTGCCCTATGAACTGCACGCCACGGCCCAGGCGAATGCCGGCGC
GGGCACGGTGACGCTGCTCTTCGCCAACACGGCCAAGACCGGCAGCCCCGCCGCGGTGTTCCACGTCTATGACAGGAAGC
ACCTGGACGCGATCCCGCGCCGCTACGTGGTCGAGGCCGGCAAGACGCTGAACGGCGTCTGGAACGTGGCGGCCGACGGC
GGCGCCTACGACCTGTGGGTGCTGGGTCCCAACGGCTTCCACCGCGCCTTCGCGGGCGACCTCGCGCAGCAGGCCTCCGC
CGGCATGCCCGAGGTGCAGGTCTGCTACGAACTGTGCGACCCGCCGCAGGTGCGCGTGAAGCTCTACAACCGCGGCACCG
CGGCCATCGGCTTCACCGCCGAGGCCCGCGCCTACCGCTCGGACGGCCCCTGGACGCGCACCGTGCAGCCCGGCGCAGTG
GAGGAACTGGCCTGGGCCCTGGGCGACAGCGGCAACTGGTACGACTTCACCGTGCGCTGCAGCGCGGCCCCTGCCTTCGT
GCGCCGCTTCGCGGGCCGCGTCGAGACGGGCCGGCATTCCGTGTCCGATCCGGCGATGGGGCAGGGGGCCTGA

Upstream 100 bases:

>100_bases
AACCCTGACACGCACTGCGCGCCCAAGCCCTGAGCCGGGCCCGCGGGCGCTCCGGCGCCTGTCCTGCCCTGCGCCTGCCG
CGACGCCGCGCGCGCGGTGC

Downstream 100 bases:

>100_bases
GCCGGAGCGGAGCGGTCACCGTTGCGACGCGATGTCCAGCGATGCCTCCGCCGCCGATTTCGCGCTCTCCGCCATGGCGA
ACCCGCCCCCGCGCCGCTTG

Product: phospholipase C

Products: NA

Alternate protein names: PLC-N; Phosphatidylcholine cholinephosphohydrolase; Phosphatidylcholine-hydrolyzing phospholipase C; PC-PLC [H]

Number of amino acids: Translated: 770; Mature: 769

Protein sequence:

>770_residues
MTRAFSYNKHSSNMTVDSSKRKFLSGVLGTGAAAATLTAFPPAIRRALAIEANNATGTIQDVQHVVLLMMENRSFDSYFG
TFKGVRGFGDRFAVPTPNGRNVFYQTYTKTTPASTYVPFRLDEAQGNAQRAGSTPHTWVDSQAAWDHGRMSRWPDAKLPL
SMGYYETAEVSFQRALADAFTLCDHYHCGMHTGTIANRLFYWTGTNGPNGISPLDGSRVRVAGLNNQFNGGNDVGASTEG
WTWTTYADRLEKAGVSWKVYQSLIDNFGCNEMMGFRHWRAEIEKMPADRKPLYVAKTDITQPQDLAGPTYDPAIDDALSP
LAKGFGNTMPQGFLETFREDIRQGRLPAVSWIIAPSVYSEHPGPSSPAQGGWYVQEVLDALTANPEVWSKTVLLINYDEN
DGFFDHLPSPAVPSRNADGSLAGACTLSAADVAVEYHDFQPATSSQPAADGKPYGPGPRVPMWVVSPWSRGGWVNSQVFD
HTSTLMFLEKRFGVAEPQISAYRRAVCGDLTSCFNFVNPNTEALPTLAGRTSKTAVDARIAAQVRAAKLPQPAAATDAAL
PVQAPGVRPSRALPYELHATAQANAGAGTVTLLFANTAKTGSPAAVFHVYDRKHLDAIPRRYVVEAGKTLNGVWNVAADG
GAYDLWVLGPNGFHRAFAGDLAQQASAGMPEVQVCYELCDPPQVRVKLYNRGTAAIGFTAEARAYRSDGPWTRTVQPGAV
EELAWALGDSGNWYDFTVRCSAAPAFVRRFAGRVETGRHSVSDPAMGQGA

Sequences:

>Translated_770_residues
MTRAFSYNKHSSNMTVDSSKRKFLSGVLGTGAAAATLTAFPPAIRRALAIEANNATGTIQDVQHVVLLMMENRSFDSYFG
TFKGVRGFGDRFAVPTPNGRNVFYQTYTKTTPASTYVPFRLDEAQGNAQRAGSTPHTWVDSQAAWDHGRMSRWPDAKLPL
SMGYYETAEVSFQRALADAFTLCDHYHCGMHTGTIANRLFYWTGTNGPNGISPLDGSRVRVAGLNNQFNGGNDVGASTEG
WTWTTYADRLEKAGVSWKVYQSLIDNFGCNEMMGFRHWRAEIEKMPADRKPLYVAKTDITQPQDLAGPTYDPAIDDALSP
LAKGFGNTMPQGFLETFREDIRQGRLPAVSWIIAPSVYSEHPGPSSPAQGGWYVQEVLDALTANPEVWSKTVLLINYDEN
DGFFDHLPSPAVPSRNADGSLAGACTLSAADVAVEYHDFQPATSSQPAADGKPYGPGPRVPMWVVSPWSRGGWVNSQVFD
HTSTLMFLEKRFGVAEPQISAYRRAVCGDLTSCFNFVNPNTEALPTLAGRTSKTAVDARIAAQVRAAKLPQPAAATDAAL
PVQAPGVRPSRALPYELHATAQANAGAGTVTLLFANTAKTGSPAAVFHVYDRKHLDAIPRRYVVEAGKTLNGVWNVAADG
GAYDLWVLGPNGFHRAFAGDLAQQASAGMPEVQVCYELCDPPQVRVKLYNRGTAAIGFTAEARAYRSDGPWTRTVQPGAV
EELAWALGDSGNWYDFTVRCSAAPAFVRRFAGRVETGRHSVSDPAMGQGA
>Mature_769_residues
TRAFSYNKHSSNMTVDSSKRKFLSGVLGTGAAAATLTAFPPAIRRALAIEANNATGTIQDVQHVVLLMMENRSFDSYFGT
FKGVRGFGDRFAVPTPNGRNVFYQTYTKTTPASTYVPFRLDEAQGNAQRAGSTPHTWVDSQAAWDHGRMSRWPDAKLPLS
MGYYETAEVSFQRALADAFTLCDHYHCGMHTGTIANRLFYWTGTNGPNGISPLDGSRVRVAGLNNQFNGGNDVGASTEGW
TWTTYADRLEKAGVSWKVYQSLIDNFGCNEMMGFRHWRAEIEKMPADRKPLYVAKTDITQPQDLAGPTYDPAIDDALSPL
AKGFGNTMPQGFLETFREDIRQGRLPAVSWIIAPSVYSEHPGPSSPAQGGWYVQEVLDALTANPEVWSKTVLLINYDEND
GFFDHLPSPAVPSRNADGSLAGACTLSAADVAVEYHDFQPATSSQPAADGKPYGPGPRVPMWVVSPWSRGGWVNSQVFDH
TSTLMFLEKRFGVAEPQISAYRRAVCGDLTSCFNFVNPNTEALPTLAGRTSKTAVDARIAAQVRAAKLPQPAAATDAALP
VQAPGVRPSRALPYELHATAQANAGAGTVTLLFANTAKTGSPAAVFHVYDRKHLDAIPRRYVVEAGKTLNGVWNVAADGG
AYDLWVLGPNGFHRAFAGDLAQQASAGMPEVQVCYELCDPPQVRVKLYNRGTAAIGFTAEARAYRSDGPWTRTVQPGAVE
ELAWALGDSGNWYDFTVRCSAAPAFVRRFAGRVETGRHSVSDPAMGQGA

Specific function: Hydrolyzes phosphatidylserine as well as phosphatidylcholine [H]

COG id: COG3511

COG function: function code M; Phospholipase C

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the bacterial phospholipase C family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR007312
- InterPro:   IPR008475
- InterPro:   IPR017767
- InterPro:   IPR006311 [H]

Pfam domain/function: PF05506 DUF756; PF04185 Phosphoesterase [H]

EC number: =3.1.4.3 [H]

Molecular weight: Translated: 83454; Mature: 83323

Theoretical pI: Translated: 7.26; Mature: 7.26

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTRAFSYNKHSSNMTVDSSKRKFLSGVLGTGAAAATLTAFPPAIRRALAIEANNATGTIQ
CCCCCCCCCCCCCCEECHHHHHHHHHHHCCCHHHHHHHHCCHHHHHEEEEECCCCCCCHH
DVQHVVLLMMENRSFDSYFGTFKGVRGFGDRFAVPTPNGRNVFYQTYTKTTPASTYVPFR
HHHHHHHHHCCCCCCHHHHHHHHHHCCCCCCCCCCCCCCCEEEEEEECCCCCCCEEEEEE
LDEAQGNAQRAGSTPHTWVDSQAAWDHGRMSRWPDAKLPLSMGYYETAEVSFQRALADAF
EECCCCCHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEECCCCHHHHHHHHHHHHHHH
TLCDHYHCGMHTGTIANRLFYWTGTNGPNGISPLDGSRVRVAGLNNQFNGGNDVGASTEG
HHHHHCCCCCCCCCHHCEEEEEECCCCCCCCCCCCCCEEEEEECCCCCCCCCCCCCCCCC
WTWTTYADRLEKAGVSWKVYQSLIDNFGCNEMMGFRHWRAEIEKMPADRKPLYVAKTDIT
CEEHHHHHHHHHCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCCCCEEEEECCCC
QPQDLAGPTYDPAIDDALSPLAKGFGNTMPQGFLETFREDIRQGRLPAVSWIIAPSVYSE
CCHHCCCCCCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCEEEEEECCHHHCC
HPGPSSPAQGGWYVQEVLDALTANPEVWSKTVLLINYDENDGFFDHLPSPAVPSRNADGS
CCCCCCCCCCCHHHHHHHHHHCCCCCCCCEEEEEEEECCCCCHHHCCCCCCCCCCCCCCC
LAGACTLSAADVAVEYHDFQPATSSQPAADGKPYGPGPRVPMWVVSPWSRGGWVNSQVFD
CEEEEEEEHHHEEEEEECCCCCCCCCCCCCCCCCCCCCCCCEEEECCCCCCCCCCCHHHH
HTSTLMFLEKRFGVAEPQISAYRRAVCGDLTSCFNFVNPNTEALPTLAGRTSKTAVDARI
HHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHCCCCCCHHHHHHH
AAQVRAAKLPQPAAATDAALPVQAPGVRPSRALPYELHATAQANAGAGTVTLLFANTAKT
HHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEECCCCCCCCCEEEEEEEECCCC
GSPAAVFHVYDRKHLDAIPRRYVVEAGKTLNGVWNVAADGGAYDLWVLGPNGFHRAFAGD
CCCEEEEEECCHHHHHHHHHHHHHHCCCCCCCEEEEEECCCEEEEEEECCCCCHHHHHHH
LAQQASAGMPEVQVCYELCDPPQVRVKLYNRGTAAIGFTAEARAYRSDGPWTRTVQPGAV
HHHHHHCCCCHHHHHHHHCCCCEEEEEEEECCCEEEEEEHHHHHCCCCCCEEECCCCCHH
EELAWALGDSGNWYDFTVRCSAAPAFVRRFAGRVETGRHSVSDPAMGQGA
HHHHHHHCCCCCEEEEEEEECCCHHHHHHHHHHCCCCCCCCCCCCCCCCC
>Mature Secondary Structure 
TRAFSYNKHSSNMTVDSSKRKFLSGVLGTGAAAATLTAFPPAIRRALAIEANNATGTIQ
CCCCCCCCCCCCCEECHHHHHHHHHHHCCCHHHHHHHHCCHHHHHEEEEECCCCCCCHH
DVQHVVLLMMENRSFDSYFGTFKGVRGFGDRFAVPTPNGRNVFYQTYTKTTPASTYVPFR
HHHHHHHHHCCCCCCHHHHHHHHHHCCCCCCCCCCCCCCCEEEEEEECCCCCCCEEEEEE
LDEAQGNAQRAGSTPHTWVDSQAAWDHGRMSRWPDAKLPLSMGYYETAEVSFQRALADAF
EECCCCCHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEECCCCHHHHHHHHHHHHHHH
TLCDHYHCGMHTGTIANRLFYWTGTNGPNGISPLDGSRVRVAGLNNQFNGGNDVGASTEG
HHHHHCCCCCCCCCHHCEEEEEECCCCCCCCCCCCCCEEEEEECCCCCCCCCCCCCCCCC
WTWTTYADRLEKAGVSWKVYQSLIDNFGCNEMMGFRHWRAEIEKMPADRKPLYVAKTDIT
CEEHHHHHHHHHCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCCCCEEEEECCCC
QPQDLAGPTYDPAIDDALSPLAKGFGNTMPQGFLETFREDIRQGRLPAVSWIIAPSVYSE
CCHHCCCCCCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCEEEEEECCHHHCC
HPGPSSPAQGGWYVQEVLDALTANPEVWSKTVLLINYDENDGFFDHLPSPAVPSRNADGS
CCCCCCCCCCCHHHHHHHHHHCCCCCCCCEEEEEEEECCCCCHHHCCCCCCCCCCCCCCC
LAGACTLSAADVAVEYHDFQPATSSQPAADGKPYGPGPRVPMWVVSPWSRGGWVNSQVFD
CEEEEEEEHHHEEEEEECCCCCCCCCCCCCCCCCCCCCCCCEEEECCCCCCCCCCCHHHH
HTSTLMFLEKRFGVAEPQISAYRRAVCGDLTSCFNFVNPNTEALPTLAGRTSKTAVDARI
HHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHCCCCCCHHHHHHH
AAQVRAAKLPQPAAATDAALPVQAPGVRPSRALPYELHATAQANAGAGTVTLLFANTAKT
HHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEECCCCCCCCCEEEEEEEECCCC
GSPAAVFHVYDRKHLDAIPRRYVVEAGKTLNGVWNVAADGGAYDLWVLGPNGFHRAFAGD
CCCEEEEEECCHHHHHHHHHHHHHHCCCCCCCEEEEEECCCEEEEEEECCCCCHHHHHHH
LAQQASAGMPEVQVCYELCDPPQVRVKLYNRGTAAIGFTAEARAYRSDGPWTRTVQPGAV
HHHHHHCCCCHHHHHHHHCCCCEEEEEEEECCCEEEEEEHHHHHCCCCCCEEECCCCCHH
EELAWALGDSGNWYDFTVRCSAAPAFVRRFAGRVETGRHSVSDPAMGQGA
HHHHHHHCCCCCEEEEEEEECCCHHHHHHHHHHCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 2120196; 10984043 [H]