Click here to switch to the map view.

The map label for this gene is minE

Identifier: 120608834

GI number: 120608834

Start: 137908

End: 138174

Strand: Direct

Name: minE

Synonym: Aave_0126

Alternate gene names: 120608834

Gene position: 137908-138174 (Clockwise)

Preceding gene: 120608833

Following gene: 120608836

Centisome position: 2.58

GC content: 61.42

Gene sequence:

>267_bases
ATGGCATCCTTTCTCTCATTCCTGCTCGGCGAAAAGAAGAAGACCGCCAGTGTCGCCAAGGAGCGGCTGCAGATCATCCT
CGCGCACGAGCGCAATGGCCGCAATGCCTCGGAGCCGGACTACCTGCCCGCGCTGCAGCGCGAACTCGTCGCCGTGATTT
CCAAATACGTGAAGATCAGCCCCGAGGACCTGAAGGTGCAGCTGGAGCGCCAGGACAACCTCGAGGTGCTCGAAGTCAAG
ATCGAGCTGCCCGACACCGTGCGCTGA

Upstream 100 bases:

>100_bases
GGACGTGGTGGCGCGCTTCCTGGGCGAGGACAAGCCCCTGCGCTTCATCGACGCGCAGAAGCCCGGCTTCTTCAAGCGCA
TTTTCGGCGGGAGGTAACGC

Downstream 100 bases:

>100_bases
GCGGCCAGGCGCGGCCGGTGGCCGCGGGCGGCTCAGAGAGGATGTTCCGTATAGAAGCGTCCGCCGTGGTAGAGCAGCGG
CGGCACGCCCGGGCGGTGCG

Product: cell division topological specificity factor MinE

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 88; Mature: 87

Protein sequence:

>88_residues
MASFLSFLLGEKKKTASVAKERLQIILAHERNGRNASEPDYLPALQRELVAVISKYVKISPEDLKVQLERQDNLEVLEVK
IELPDTVR

Sequences:

>Translated_88_residues
MASFLSFLLGEKKKTASVAKERLQIILAHERNGRNASEPDYLPALQRELVAVISKYVKISPEDLKVQLERQDNLEVLEVK
IELPDTVR
>Mature_87_residues
ASFLSFLLGEKKKTASVAKERLQIILAHERNGRNASEPDYLPALQRELVAVISKYVKISPEDLKVQLERQDNLEVLEVKI
ELPDTVR

Specific function: Prevents the cell division inhibition by proteins minC and minD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the l

COG id: COG0851

COG function: function code D; Septum formation topological specificity factor

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the minE family

Homologues:

Organism=Escherichia coli, GI1787422, Length=85, Percent_Identity=48.2352941176471, Blast_Score=80, Evalue=2e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): MINE_ACIAC (A1TIF0)

Other databases:

- EMBL:   CP000512
- RefSeq:   YP_968512.1
- ProteinModelPortal:   A1TIF0
- SMR:   A1TIF0
- STRING:   A1TIF0
- GeneID:   4667353
- GenomeReviews:   CP000512_GR
- KEGG:   aav:Aave_0126
- NMPDR:   fig|397945.5.peg.108
- eggNOG:   COG0851
- HOGENOM:   HBG449956
- OMA:   HERSGRN
- PhylomeDB:   A1TIF0
- ProtClustDB:   PRK13989
- BioCyc:   AAVE397945:AAVE_0126-MONOMER
- HAMAP:   MF_00262
- InterPro:   IPR005527
- TIGRFAMs:   TIGR01215

Pfam domain/function: PF03776 MinE

EC number: NA

Molecular weight: Translated: 10031; Mature: 9900

Theoretical pI: Translated: 7.54; Mature: 7.54

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
1.1 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
0.0 %Met     (Mature Protein)
0.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MASFLSFLLGEKKKTASVAKERLQIILAHERNGRNASEPDYLPALQRELVAVISKYVKIS
CHHHHHHHHCCCCHHHHHHHHHHHHHEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHCCC
PEDLKVQLERQDNLEVLEVKIELPDTVR
CHHHEEEECCCCCEEEEEEEECCCCCCC
>Mature Secondary Structure 
ASFLSFLLGEKKKTASVAKERLQIILAHERNGRNASEPDYLPALQRELVAVISKYVKIS
HHHHHHHHCCCCHHHHHHHHHHHHHEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHCCC
PEDLKVQLERQDNLEVLEVKIELPDTVR
CHHHEEEECCCCCEEEEEEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA