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The map label for this gene is gidB

Identifier: 120608763

GI number: 120608763

Start: 58639

End: 59370

Strand: Direct

Name: gidB

Synonym: Aave_0052

Alternate gene names: 120608763

Gene position: 58639-59370 (Clockwise)

Preceding gene: 120608762

Following gene: 120608764

Centisome position: 1.1

GC content: 68.58

Gene sequence:

>732_bases
GTGACGGTGGCTGCCGACGCTTTGTCGGCACCTCTGCGTGCAGGGGCGGAGGCCCTGGGCCTGGATCTGTCGGAGGCCCA
CCTGGGGCAATTGCTGGAGTTCCTGGCCCTGCTGCAGAAGTGGAACCAGGTCTATAACCTGACGGCGGTGCGTGATCCGC
AGGAGATGCTCACGCACCACCTGCTCGACAGCCTCGCGGCGGTGGCGCCGCTGCAGCGCCATCTCCGGGGGATGCAGGAC
CTGCCGGGCAGCGCGGGCGATGGCGCCAAGCTGCGCCTGCTGGATGTGGGTTCGGGCGGTGGCCTGCCGGGCGTGGTGTT
CGCCATCTGCTGTCCCGCGCTGGACGTGAGCTGTGTGGATACGGTGGCCAAGAAGGCGGCCTTCATCCAGCAGGCCGCCG
TGTCGCTGCGGCTGCGCAACCTGCGAGGCATCCATGCGCGTGTGGAAAACCTGGCGGGGCCGTTCGACGTGGTGAGCTGC
CGGGCGTTCGCCTCGCTGCCGGATTTCGTGGCGTGGTCGCAGGCGGCTATCGCCGCGAACGGCGTTTGGCTGGCGATGAA
GGGCCGTGACCCGTCCGATGAAATCACCGGACTGCCTCCCATCGCGGAAGTGTTCCACGTGGAACAACTCGCCGTGCCGG
GCCTCGACGCCGAACGGTGCATTGTCTGGATGCGGCCGCGAAAGGGTGCCGAAGCCGGCGCGGATGGCGTGGGCGGTCCA
GCCCTGCCTTAA

Upstream 100 bases:

>100_bases
TTTCCGGGGTGACGCCGGCCGCGGTATCGCTGTTGCTGGTGCACCTGAAGAAGGGCGGCTTCCGGGGCTTCACGGCCCAG
CAGGCTGACGAGGTGGCCGC

Downstream 100 bases:

>100_bases
ACTCCCGCTTCCAATTTTCGGGGGTGCTGATGTTTGGCATTGCGGACTACGGCGCATTCGTCGCCGCCATCCTGTTGTTC
CTGGCCATTCCCGGCCCGGG

Product: 16S rRNA methyltransferase GidB

Products: NA

Alternate protein names: 16S rRNA 7-methylguanosine methyltransferase; 16S rRNA m7G methyltransferase

Number of amino acids: Translated: 243; Mature: 242

Protein sequence:

>243_residues
MTVAADALSAPLRAGAEALGLDLSEAHLGQLLEFLALLQKWNQVYNLTAVRDPQEMLTHHLLDSLAAVAPLQRHLRGMQD
LPGSAGDGAKLRLLDVGSGGGLPGVVFAICCPALDVSCVDTVAKKAAFIQQAAVSLRLRNLRGIHARVENLAGPFDVVSC
RAFASLPDFVAWSQAAIAANGVWLAMKGRDPSDEITGLPPIAEVFHVEQLAVPGLDAERCIVWMRPRKGAEAGADGVGGP
ALP

Sequences:

>Translated_243_residues
MTVAADALSAPLRAGAEALGLDLSEAHLGQLLEFLALLQKWNQVYNLTAVRDPQEMLTHHLLDSLAAVAPLQRHLRGMQD
LPGSAGDGAKLRLLDVGSGGGLPGVVFAICCPALDVSCVDTVAKKAAFIQQAAVSLRLRNLRGIHARVENLAGPFDVVSC
RAFASLPDFVAWSQAAIAANGVWLAMKGRDPSDEITGLPPIAEVFHVEQLAVPGLDAERCIVWMRPRKGAEAGADGVGGP
ALP
>Mature_242_residues
TVAADALSAPLRAGAEALGLDLSEAHLGQLLEFLALLQKWNQVYNLTAVRDPQEMLTHHLLDSLAAVAPLQRHLRGMQDL
PGSAGDGAKLRLLDVGSGGGLPGVVFAICCPALDVSCVDTVAKKAAFIQQAAVSLRLRNLRGIHARVENLAGPFDVVSCR
AFASLPDFVAWSQAAIAANGVWLAMKGRDPSDEITGLPPIAEVFHVEQLAVPGLDAERCIVWMRPRKGAEAGADGVGGPA
LP

Specific function: Specifically methylates the N7 position of guanosine in position 527 of 16S rRNA

COG id: COG0357

COG function: function code M; Predicted S-adenosylmethionine-dependent methyltransferase involved in bacterial cell division

Gene ontology:

Cell location: Cytoplasm (Potential)

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the methyltransferase superfamily. RNA methyltransferase rsmG family

Homologues:

Organism=Escherichia coli, GI1790179, Length=211, Percent_Identity=39.3364928909953, Blast_Score=150, Evalue=7e-38,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): RSMG_ACIAC (A1TI79)

Other databases:

- EMBL:   CP000512
- RefSeq:   YP_968441.1
- ProteinModelPortal:   A1TI79
- SMR:   A1TI79
- STRING:   A1TI79
- GeneID:   4666794
- GenomeReviews:   CP000512_GR
- KEGG:   aav:Aave_0052
- NMPDR:   fig|397945.5.peg.43
- eggNOG:   COG0357
- HOGENOM:   HBG686577
- OMA:   HIMDSIV
- PhylomeDB:   A1TI79
- ProtClustDB:   PRK00107
- BioCyc:   AAVE397945:AAVE_0052-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00074
- InterPro:   IPR003682
- PIRSF:   PIRSF003078
- TIGRFAMs:   TIGR00138

Pfam domain/function: PF02527 GidB

EC number: =2.1.1.170

Molecular weight: Translated: 25502; Mature: 25371

Theoretical pI: Translated: 5.93; Mature: 5.93

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTVAADALSAPLRAGAEALGLDLSEAHLGQLLEFLALLQKWNQVYNLTAVRDPQEMLTHH
CCCCCHHHHHHHHHCHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHH
LLDSLAAVAPLQRHLRGMQDLPGSAGDGAKLRLLDVGSGGGLPGVVFAICCPALDVSCVD
HHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEEECCCCCHHHHHHHHHHHCCCHHHHH
TVAKKAAFIQQAAVSLRLRNLRGIHARVENLAGPFDVVSCRAFASLPDFVAWSQAAIAAN
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCHHHHHHHHHHEEC
GVWLAMKGRDPSDEITGLPPIAEVFHVEQLAVPGLDAERCIVWMRPRKGAEAGADGVGGP
CEEEEEECCCCCCCCCCCCHHHHHHHHHHHHCCCCCHHHEEEEECCCCCCCCCCCCCCCC
ALP
CCC
>Mature Secondary Structure 
TVAADALSAPLRAGAEALGLDLSEAHLGQLLEFLALLQKWNQVYNLTAVRDPQEMLTHH
CCCCHHHHHHHHHCHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHH
LLDSLAAVAPLQRHLRGMQDLPGSAGDGAKLRLLDVGSGGGLPGVVFAICCPALDVSCVD
HHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEEECCCCCHHHHHHHHHHHCCCHHHHH
TVAKKAAFIQQAAVSLRLRNLRGIHARVENLAGPFDVVSCRAFASLPDFVAWSQAAIAAN
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCHHHHHHHHHHEEC
GVWLAMKGRDPSDEITGLPPIAEVFHVEQLAVPGLDAERCIVWMRPRKGAEAGADGVGGP
CEEEEEECCCCCCCCCCCCHHHHHHHHHHHHCCCCCHHHEEEEECCCCCCCCCCCCCCCC
ALP
CCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA