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The map label for this gene is tauC [H]

Identifier: 120608758

GI number: 120608758

Start: 53864

End: 54784

Strand: Direct

Name: tauC [H]

Synonym: Aave_0047

Alternate gene names: 120608758

Gene position: 53864-54784 (Clockwise)

Preceding gene: 120608757

Following gene: 120608762

Centisome position: 1.01

GC content: 71.44

Gene sequence:

>921_bases
ATGTCCATGCCTGAGGAAGCGTTGATGCCGTCGCTCCCCGGCATGGCGGCGCAGCCCCGGCGCGAGGCTGCTGCGCCGGG
TCCGACCCTGGCGCCTGCGGAGGCCGCCCCGTCGCCCGCCTTGCGGGCCGTTGCCCCGTACCGCCTGCCTGGCCAGGGGC
CGAGCCGGGGCCTGAGCGTGGCCTGCGTCGCCGCATTCGCGCTGCTGTGGTGGCTGGCCACGCAGTTGCAGTGGGTCAAA
CCGCTGTTCCTGCCCGCACCCCAGGCCGTGCTGCTGGCGCTGCGCGATGCCTGGGAAGGGCGCATCCAGGGCGGGGAACC
CCTGTGGCGGCACCTGCAGTGGAGCGCGATCCGGGTCTTCGGCGCTTTCGTGCTCGCGGCCCTGACGGCGGTTCCCGTCG
GCATCGCCATGGGGGTGAGCCGCGTGGCGCGCGGCGTGTTCGATCCACCCATCGAGTTCTACCGGCCGCTGCCGCCGCTG
GCCTACCTGCCGCTCATCGTCATCTGGTTCGGCATCGACGAGACGGCCAAGATCCTGCTGATCTACCTCGCCTGCTTCGC
GCCCATCGCGCTGGCAGCGCGGGCCGGAGTGCGCAGCGCGAGCGTGGAGCAGGTCCATGCCGCGCTGTCGCTGGGCGCGA
GCCGCTGGCAGCTGGTGCGGCACGTGATCGTGCCGGCGGCACTGCCCGAGATCCTGGTGGGGCTGCGCATCGCCATCGGT
TTCGGCTGGACGACGCTGGTAGCCGCGGAAATGGTGGCGGCAACGGTGGGCATCGGTCAGATGGTGCTCAATGCCTCGAA
CTTCCTGCGCACCGACCTCGTGGTGGCCGGCATCCTGGTGATCGGCCTGGTGGCCTGGACATTCGATCTGGTCATGCGCT
GGGTGGAGGCCCGCGCAGTGCCCTGGAAGGGACGGGCCTGA

Upstream 100 bases:

>100_bases
TCCAGCTCGGCTTTCATCGACGGGCGTGAGCGTGTTCTGGACGAGGTGGCGCCATCGCTGGCCCCGCAGGCAGCGGCCCG
GCAACCGGAGCACGTGGAGC

Downstream 100 bases:

>100_bases
ACGCGGGCCCGTCCTGTTCCTGCAAGCCTGGGAAGGCTTACTTCTGCAGGCCCTCTGCCTTGAGGGCGGCCTGCACGGCC
GGGCGGGAGCCCACGCGTGC

Product: binding-protein-dependent transport systems inner membrane component

Products: taurine [Cytoplasm]; ADP; phosphate [C]

Alternate protein names: NA

Number of amino acids: Translated: 306; Mature: 305

Protein sequence:

>306_residues
MSMPEEALMPSLPGMAAQPRREAAAPGPTLAPAEAAPSPALRAVAPYRLPGQGPSRGLSVACVAAFALLWWLATQLQWVK
PLFLPAPQAVLLALRDAWEGRIQGGEPLWRHLQWSAIRVFGAFVLAALTAVPVGIAMGVSRVARGVFDPPIEFYRPLPPL
AYLPLIVIWFGIDETAKILLIYLACFAPIALAARAGVRSASVEQVHAALSLGASRWQLVRHVIVPAALPEILVGLRIAIG
FGWTTLVAAEMVAATVGIGQMVLNASNFLRTDLVVAGILVIGLVAWTFDLVMRWVEARAVPWKGRA

Sequences:

>Translated_306_residues
MSMPEEALMPSLPGMAAQPRREAAAPGPTLAPAEAAPSPALRAVAPYRLPGQGPSRGLSVACVAAFALLWWLATQLQWVK
PLFLPAPQAVLLALRDAWEGRIQGGEPLWRHLQWSAIRVFGAFVLAALTAVPVGIAMGVSRVARGVFDPPIEFYRPLPPL
AYLPLIVIWFGIDETAKILLIYLACFAPIALAARAGVRSASVEQVHAALSLGASRWQLVRHVIVPAALPEILVGLRIAIG
FGWTTLVAAEMVAATVGIGQMVLNASNFLRTDLVVAGILVIGLVAWTFDLVMRWVEARAVPWKGRA
>Mature_305_residues
SMPEEALMPSLPGMAAQPRREAAAPGPTLAPAEAAPSPALRAVAPYRLPGQGPSRGLSVACVAAFALLWWLATQLQWVKP
LFLPAPQAVLLALRDAWEGRIQGGEPLWRHLQWSAIRVFGAFVLAALTAVPVGIAMGVSRVARGVFDPPIEFYRPLPPLA
YLPLIVIWFGIDETAKILLIYLACFAPIALAARAGVRSASVEQVHAALSLGASRWQLVRHVIVPAALPEILVGLRIAIGF
GWTTLVAAEMVAATVGIGQMVLNASNFLRTDLVVAGILVIGLVAWTFDLVMRWVEARAVPWKGRA

Specific function: Part of a binding-protein-dependent transport system for taurine. Probably responsible for the translocation of the substrate across the membrane [H]

COG id: COG0600

COG function: function code P; ABC-type nitrate/sulfonate/bicarbonate transport system, permease component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1786564, Length=248, Percent_Identity=53.2258064516129, Blast_Score=226, Evalue=1e-60,
Organism=Escherichia coli, GI87081802, Length=235, Percent_Identity=36.5957446808511, Blast_Score=134, Evalue=8e-33,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000515 [H]

Pfam domain/function: PF00528 BPD_transp_1 [H]

EC number: NA

Molecular weight: Translated: 32741; Mature: 32610

Theoretical pI: Translated: 10.49; Mature: 10.49

Prosite motif: PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSMPEEALMPSLPGMAAQPRREAAAPGPTLAPAEAAPSPALRAVAPYRLPGQGPSRGLSV
CCCCHHHHCCCCCCCCCCCCHHCCCCCCCCCCCCCCCCCHHHHCCCCCCCCCCCCCCHHH
ACVAAFALLWWLATQLQWVKPLFLPAPQAVLLALRDAWEGRIQGGEPLWRHLQWSAIRVF
HHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHH
GAFVLAALTAVPVGIAMGVSRVARGVFDPPIEFYRPLPPLAYLPLIVIWFGIDETAKILL
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHCCCCCHHHHHHHHHHHCCCHHHHHHH
IYLACFAPIALAARAGVRSASVEQVHAALSLGASRWQLVRHVIVPAALPEILVGLRIAIG
HHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FGWTTLVAAEMVAATVGIGQMVLNASNFLRTDLVVAGILVIGLVAWTFDLVMRWVEARAV
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
PWKGRA
CCCCCC
>Mature Secondary Structure 
SMPEEALMPSLPGMAAQPRREAAAPGPTLAPAEAAPSPALRAVAPYRLPGQGPSRGLSV
CCCHHHHCCCCCCCCCCCCHHCCCCCCCCCCCCCCCCCHHHHCCCCCCCCCCCCCCHHH
ACVAAFALLWWLATQLQWVKPLFLPAPQAVLLALRDAWEGRIQGGEPLWRHLQWSAIRVF
HHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHH
GAFVLAALTAVPVGIAMGVSRVARGVFDPPIEFYRPLPPLAYLPLIVIWFGIDETAKILL
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHCCCCCHHHHHHHHHHHCCCHHHHHHH
IYLACFAPIALAARAGVRSASVEQVHAALSLGASRWQLVRHVIVPAALPEILVGLRIAIG
HHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FGWTTLVAAEMVAATVGIGQMVLNASNFLRTDLVVAGILVIGLVAWTFDLVMRWVEARAV
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
PWKGRA
CCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: taurine [Periplasm]; ATP; H2O [C]

Specific reaction: taurine [Periplasm] + ATP + H2O = taurine [Cytoplasm] + ADP + phosphate [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 8808933; 9278503 [H]