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The map label for this gene is basS [H]

Identifier: 120608755

GI number: 120608755

Start: 48630

End: 50078

Strand: Direct

Name: basS [H]

Synonym: Aave_0042

Alternate gene names: 120608755

Gene position: 48630-50078 (Clockwise)

Preceding gene: 120608754

Following gene: 120608757

Centisome position: 0.91

GC content: 73.91

Gene sequence:

>1449_bases
ATGAGCGGCGGTACGCCTGCCGCGGCCCTGCCGCAGAGGCCGGCCCCCTCGCCGCCCTCGCTGCGTGCACGCCTGTTGCG
CCATGTGCTGGTACCACTGGCGCTCACCTGGTTCGCGGGCACGGCCATCTCGGTGCTGGTGGCCAACGGGTTCACGCAGC
GCGCCTTCGACCGGGCGCTGCTGGACGACGCCTATGCCATCGCGGCCAATGTGCGGGTCAAGGGCGGGGCGCTGGACCTG
GCGCTGAGTTCGCGCGAGCTCAAGTCGGTGCTGTTCGACCAGGCGGAGACGGTGTATTTCGCCGTGCTGCTGCCCGGCGG
GTCGATGCTCTCGGGCAATGCCAGCCTGCCGGTGCCGCCGCCGCCGCGCGACGAGGCCTATCGCTTCTCCGACATCAGCT
ACCGCGGACGGGCACTGCGGGCCGTGCGGGTGCGGGTGAACGAGCCGCAGGCCTTCGAGGTCATCACCGCCCAGACGGTG
CATGCGCGCAGCGCCATGCTGCGCGGCGTGCTGCTGTATTCGGTGGTGTCGCAGGTACTGCTGCTGGGCGCGCTGGCGTT
CTGGCTGCGGCGGGCCATCCAGTCGGACCTGCAGCCCCTGGCGGCGTTCCAGTCGGAGCTGGCGGGCCGCGATGCGCGGG
ACCTGGAGCCGGTGGCGGTGCAGGCCTCCACGCGCGATCTGCAGCACCTGGGCGCTGCCGTGAACGGCCTGCTGGCGCGG
GTGGCCGAGGGCGTGCGCGCGCAGCGGGAGTTCGCCGGCAACGTGGCGCACGAGCTGCGCACGCCGCTGGCGGGCATCCG
GGCGCTCGCGGCCTATGGCCTGGCCCACAAGGACCCGGCCGTGTGGCACGAGCAGCTCGCCGGCGTGGCCGCCAGCGAGG
CCCGCGCCAGCCACCTCGTGGACCAGTTGCTGGCCCTGGCGCTGGCCGACGAGGTGCGCGGTGCCGTGCCGCGCCAGCCC
GTGGCGCTGGACGATCTGGCGCGGGATGCCGTGCTGCGCTTCCTGCCGCGTGCCGACGCGGCGGGCGTGGACCTGGGTGC
CCGCGGGCTGGACCAGCCCGTGGTGGTGCAGGGGCAGACCGTGCTGATCGAAGGTGTGCTGGGCAACCTGATCGACAACG
CGCTGCGCTACGGCCGCCCGGCGCAGGAAGGCGTGGGGCCGCGCATCACCGTGGAGATCGCTCATGAGCAGGCGGAAAAC
GGGACGGGCGAGGTCGTGCTGTCGGTGGTGGACAACGGCCCTGGCATCCCGCAGGGGCTGCGCACCGACCTGATGCAGCG
CTGGGCCCAGGGCCGCGAGGGCGAGCGCCTGGGGCAGGGCGCGGGCCTGGGCCTGGCCATCGTGGCGCGCTATGCCGAGC
TGCTGGGCGCGCGCCTGGTGCTGGGCACGGGCCCGGACGCGGAGGGGCTGCGGGTGGGGCTGGTGTTCGTTCCCGTGGAG
CCAGCCTAA

Upstream 100 bases:

>100_bases
TGCGCAAGAAGCTGCAGGGCAGCGGCGCCGGCATCCGCACGCTGCGCGGGCTGGGCTACATGCTGGAGGCGACCGACGCC
TCCGCGACGCAAGGGGATGC

Downstream 100 bases:

>100_bases
GCCGGCCCGGTGCCGAACACCGGCCGGAAGAAACTGCGCTCGTAGCTCACGATGCAGCGGGTCTCTTCCGCGTACCGGAA
GGCCGCGAGGCATTCGGCGT

Product: integral membrane sensor signal transduction histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 482; Mature: 481

Protein sequence:

>482_residues
MSGGTPAAALPQRPAPSPPSLRARLLRHVLVPLALTWFAGTAISVLVANGFTQRAFDRALLDDAYAIAANVRVKGGALDL
ALSSRELKSVLFDQAETVYFAVLLPGGSMLSGNASLPVPPPPRDEAYRFSDISYRGRALRAVRVRVNEPQAFEVITAQTV
HARSAMLRGVLLYSVVSQVLLLGALAFWLRRAIQSDLQPLAAFQSELAGRDARDLEPVAVQASTRDLQHLGAAVNGLLAR
VAEGVRAQREFAGNVAHELRTPLAGIRALAAYGLAHKDPAVWHEQLAGVAASEARASHLVDQLLALALADEVRGAVPRQP
VALDDLARDAVLRFLPRADAAGVDLGARGLDQPVVVQGQTVLIEGVLGNLIDNALRYGRPAQEGVGPRITVEIAHEQAEN
GTGEVVLSVVDNGPGIPQGLRTDLMQRWAQGREGERLGQGAGLGLAIVARYAELLGARLVLGTGPDAEGLRVGLVFVPVE
PA

Sequences:

>Translated_482_residues
MSGGTPAAALPQRPAPSPPSLRARLLRHVLVPLALTWFAGTAISVLVANGFTQRAFDRALLDDAYAIAANVRVKGGALDL
ALSSRELKSVLFDQAETVYFAVLLPGGSMLSGNASLPVPPPPRDEAYRFSDISYRGRALRAVRVRVNEPQAFEVITAQTV
HARSAMLRGVLLYSVVSQVLLLGALAFWLRRAIQSDLQPLAAFQSELAGRDARDLEPVAVQASTRDLQHLGAAVNGLLAR
VAEGVRAQREFAGNVAHELRTPLAGIRALAAYGLAHKDPAVWHEQLAGVAASEARASHLVDQLLALALADEVRGAVPRQP
VALDDLARDAVLRFLPRADAAGVDLGARGLDQPVVVQGQTVLIEGVLGNLIDNALRYGRPAQEGVGPRITVEIAHEQAEN
GTGEVVLSVVDNGPGIPQGLRTDLMQRWAQGREGERLGQGAGLGLAIVARYAELLGARLVLGTGPDAEGLRVGLVFVPVE
PA
>Mature_481_residues
SGGTPAAALPQRPAPSPPSLRARLLRHVLVPLALTWFAGTAISVLVANGFTQRAFDRALLDDAYAIAANVRVKGGALDLA
LSSRELKSVLFDQAETVYFAVLLPGGSMLSGNASLPVPPPPRDEAYRFSDISYRGRALRAVRVRVNEPQAFEVITAQTVH
ARSAMLRGVLLYSVVSQVLLLGALAFWLRRAIQSDLQPLAAFQSELAGRDARDLEPVAVQASTRDLQHLGAAVNGLLARV
AEGVRAQREFAGNVAHELRTPLAGIRALAAYGLAHKDPAVWHEQLAGVAASEARASHLVDQLLALALADEVRGAVPRQPV
ALDDLARDAVLRFLPRADAAGVDLGARGLDQPVVVQGQTVLIEGVLGNLIDNALRYGRPAQEGVGPRITVEIAHEQAENG
TGEVVLSVVDNGPGIPQGLRTDLMQRWAQGREGERLGQGAGLGLAIVARYAELLGARLVLGTGPDAEGLRVGLVFVPVEP
A

Specific function: Member of the two-component regulatory system BasS/BasR Autophosphorylates and activates BasR by phosphorylation [H]

COG id: COG0642

COG function: function code T; Signal transduction histidine kinase

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 histidine kinase domain [H]

Homologues:

Organism=Escherichia coli, GI1790551, Length=305, Percent_Identity=31.4754098360656, Blast_Score=104, Evalue=1e-23,
Organism=Escherichia coli, GI1789403, Length=457, Percent_Identity=25.164113785558, Blast_Score=87, Evalue=2e-18,
Organism=Escherichia coli, GI1788279, Length=321, Percent_Identity=25.5451713395639, Blast_Score=75, Evalue=8e-15,
Organism=Escherichia coli, GI1788393, Length=259, Percent_Identity=28.1853281853282, Blast_Score=66, Evalue=4e-12,
Organism=Escherichia coli, GI1789149, Length=297, Percent_Identity=23.9057239057239, Blast_Score=65, Evalue=7e-12,
Organism=Escherichia coli, GI1786783, Length=331, Percent_Identity=22.9607250755287, Blast_Score=64, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR003660
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF00672 HAMP; PF02518 HATPase_c; PF00512 HisKA [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 50958; Mature: 50827

Theoretical pI: Translated: 7.33; Mature: 7.33

Prosite motif: PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
0.8 %Met     (Translated Protein)
0.8 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
0.6 %Met     (Mature Protein)
0.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSGGTPAAALPQRPAPSPPSLRARLLRHVLVPLALTWFAGTAISVLVANGFTQRAFDRAL
CCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHH
LDDAYAIAANVRVKGGALDLALSSRELKSVLFDQAETVYFAVLLPGGSMLSGNASLPVPP
HHHHHHEEEEEEEECCEEEEEECHHHHHHHHHCCCCEEEEEEEECCCCEECCCCCCCCCC
PPRDEAYRFSDISYRGRALRAVRVRVNEPQAFEVITAQTVHARSAMLRGVLLYSVVSQVL
CCCCCCEEECCCCCCCCEEEEEEEEECCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHH
LLGALAFWLRRAIQSDLQPLAAFQSELAGRDARDLEPVAVQASTRDLQHLGAAVNGLLAR
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEECHHHHHHHHHHHHHHHHHH
VAEGVRAQREFAGNVAHELRTPLAGIRALAAYGLAHKDPAVWHEQLAGVAASEARASHLV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHH
DQLLALALADEVRGAVPRQPVALDDLARDAVLRFLPRADAAGVDLGARGLDQPVVVQGQT
HHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCEEECCCE
VLIEGVLGNLIDNALRYGRPAQEGVGPRITVEIAHEQAENGTGEVVLSVVDNGPGIPQGL
EEEHHHHHHHHHHHHHCCCCHHHCCCCEEEEEEECHHCCCCCCEEEEEEECCCCCCCHHH
RTDLMQRWAQGREGERLGQGAGLGLAIVARYAELLGARLVLGTGPDAEGLRVGLVFVPVE
HHHHHHHHHCCCCCCHHCCCCCHHHHHHHHHHHHHCCEEEEECCCCCCCEEEEEEEEECC
PA
CC
>Mature Secondary Structure 
SGGTPAAALPQRPAPSPPSLRARLLRHVLVPLALTWFAGTAISVLVANGFTQRAFDRAL
CCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHH
LDDAYAIAANVRVKGGALDLALSSRELKSVLFDQAETVYFAVLLPGGSMLSGNASLPVPP
HHHHHHEEEEEEEECCEEEEEECHHHHHHHHHCCCCEEEEEEEECCCCEECCCCCCCCCC
PPRDEAYRFSDISYRGRALRAVRVRVNEPQAFEVITAQTVHARSAMLRGVLLYSVVSQVL
CCCCCCEEECCCCCCCCEEEEEEEEECCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHH
LLGALAFWLRRAIQSDLQPLAAFQSELAGRDARDLEPVAVQASTRDLQHLGAAVNGLLAR
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEECHHHHHHHHHHHHHHHHHH
VAEGVRAQREFAGNVAHELRTPLAGIRALAAYGLAHKDPAVWHEQLAGVAASEARASHLV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHH
DQLLALALADEVRGAVPRQPVALDDLARDAVLRFLPRADAAGVDLGARGLDQPVVVQGQT
HHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCEEECCCE
VLIEGVLGNLIDNALRYGRPAQEGVGPRITVEIAHEQAENGTGEVVLSVVDNGPGIPQGL
EEEHHHHHHHHHHHHHCCCCHHHCCCCEEEEEEECHHCCCCCCEEEEEEECCCCCCCHHH
RTDLMQRWAQGREGERLGQGAGLGLAIVARYAELLGARLVLGTGPDAEGLRVGLVFVPVE
HHHHHHHHHCCCCCCHHCCCCCHHHHHHHHHHHHHCCEEEEECCCCCCCEEEEEEEEECC
PA
CC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8282725; 7610040; 9278503 [H]